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crossover experiment     
相关语句
  交叉实验
     In the crossover experiment designed study,the plasma in the six dogs was determined and the bioequivalence was assessed by 6 factors analysis of variance and two or one side test.
     采用交叉实验设计 ,对 6条健康家犬体内血药复方阿司匹林 /双嘧达莫缓释片浓度进行实际测定 ,采用三因素方差分析及双单侧检验进行生物等效性研究。
短句来源
  交叉实验
     In the crossover experiment designed study,the plasma in the six dogs was determined and the bioequivalence was assessed by 6 factors analysis of variance and two or one side test.
     采用交叉实验设计 ,对 6条健康家犬体内血药复方阿司匹林 /双嘧达莫缓释片浓度进行实际测定 ,采用三因素方差分析及双单侧检验进行生物等效性研究。
短句来源
  “crossover experiment”译为未确定词的双语例句
     THE TEST PRINCIPLE BY COMBINING CROSS OVER EXPERIMENT WITH ALGEBRAIC METHOD
     正交试验法与代数法的联用原理
短句来源
     In the process of microwave processing, in addition to heat effect of microwave, non-heat effect of microwave also exists, which increases the rate of activation process and decreases activated energy of reactionThe effects of power of microwave, radiation time and activated carbon sizes on desulfurization were studied by a Crossover experiment.
     应用正交实验研究了微波功率、辐照时间、活性炭粒径对微波改性活性炭脱硫效果的影响,显示微波功率是决定改性活性炭502吸附容量的关键因素,微波功率的增加可以加强改性活性炭的502吸附能力,辐照时间对活性炭改性的影响在4一smin内突出,活性炭粒径越小,改性效果越好,对50:吸附容量也越大。
短句来源
     Method Eight male healthy young volunteers were exposed to two 24 h periods of continuous wakefulness during the crossover experiment. In one period, 200 mg doses of modafinil were given and in the other, separated by one week, matching placebos were administered. The SD time started from 8:00 of the first day to 8:00 of the second day.
     方法以8名健康男性青年志愿者为对象,在间隔1周的两次24h SD(从第1天8:00至第2天8:00)实验中交叉服用莫达非尼和安慰剂200mg(于第2天0:00服用),于第1天21:00及服药后1h、3h、5h、7h进行前庭功能测定。
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  相似匹配句对
     experiment:
     二、维生素E干预实验研究结果显示:
短句来源
     In the experiment:
     在实验中:
短句来源
     2. Subject crossover.
     其次,学科交叉研究。
短句来源
     Self-crossover Operator
     自交叉算子
短句来源
     Poetry Slam And Crossover
     “诗歌角斗”与跨界表演
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  crossover experiment
Rats were given dFUR alone (500 mg kg-1) and dFUR (300 mg kg-1) plus UR (4.5 g kg-1) in a random crossover experiment.
      
The effects of three gastric antisecretory drugs on the pharmacokinetics of ethanol have been studied in a randomized crossover experiment.
      
The marijuana-induced acute memory impairment was assessed in a double-blind, crossover experiment.
      
Naloxone-induced hyperalgesia before and after 20 min of intermittent shock was assessed in a 3-day placebo crossover experiment designed to provide control comparisons of time effects.
      
In a double-blind, double crossover experiment, 18 healthy young men received over 3-day periods either 100 mg atenolol, 80 mg propranolol, or placebo.
      
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Objective To investigate the effects of modafinil, a new central stimulant, on visual and auditory motion reaction ability and subjective fatigue level during 48 h sleep deprivation(SD). Method Six male healthy young volunteers were exposed to two 48 h periods of continuous wakefulness during the crossover experiment. In one period, three 200 mg doses of modafinil were given and in the other, separated by two weeks, matching placebos were administered. The SD time started from 7∶00 of the first day to...

Objective To investigate the effects of modafinil, a new central stimulant, on visual and auditory motion reaction ability and subjective fatigue level during 48 h sleep deprivation(SD). Method Six male healthy young volunteers were exposed to two 48 h periods of continuous wakefulness during the crossover experiment. In one period, three 200 mg doses of modafinil were given and in the other, separated by two weeks, matching placebos were administered. The SD time started from 7∶00 of the first day to 7∶00 of the third day. Drugs were given at 0∶00,16∶00 of the second day and 0:00 of the third day. Variables, including visual and auditory motion reaction time, attention distribution, critical flicker fusion frequency(CFF), Stanford sleepiness scale(SSS) and rating of perceived exertion(RPE), were tested at 21∶00 of the first day and 1,3,5,7 h after each drug administration. Result After 2~3 does of modafinil ,the CFF level was obviously enhanced while the scores of Stanford sleepiness scale and RPE were markedly reduced. The visual and auditory motion reaction ability, as well as the attention distribution, showed no significant change. Conclusion Modafinil can effectively reduced the subjective fatigue and sleepiness levels during SD.

目的观察 48h睡眠剥夺 (sleepdeprivation ,SD)条件下正常人服用新型促醒剂莫达芬尼改善视听反应能力和疲劳感的效果。方法 6名健康男性青年志愿者 ,在 2次SD实验 (间隔 2周 )中交叉服用莫达芬尼和安慰剂 ,SD时间从第 1天 7∶0 0至第 3天 7∶0 0 ,于第 2天 0∶0 0、1 6∶0 0和第 3天 0∶0 0分别服用莫达芬尼 2 0 0mg或安慰剂 ,采用随机双盲给药 ,并在第 1天 2 1∶0 0及每次服药后 1h、3h、5h、7h各完成 1次测试 ,内容包括 :1 )声、光刺激运动反应时 ;2 )注意分配 ;3)临界闪光融合频率 (criticalflickerfusionfre quency ,CFF) ;4) .斯坦福嗜睡量表 (stanfordsleepinessscale ,SSS) ;5 )自认疲劳分级表 (ratingofper ceivedexertion ,RPE)。结果与安慰剂组比较 ,第 2、3次服用莫达芬尼后CFF值较安慰剂组明显升高 ,斯坦福量嗜睡表、RPE表分值较安慰剂组明显下降 ;声、光刺激运动反应时与注意分配无明显变化。结论莫达芬尼能明显...

目的观察 48h睡眠剥夺 (sleepdeprivation ,SD)条件下正常人服用新型促醒剂莫达芬尼改善视听反应能力和疲劳感的效果。方法 6名健康男性青年志愿者 ,在 2次SD实验 (间隔 2周 )中交叉服用莫达芬尼和安慰剂 ,SD时间从第 1天 7∶0 0至第 3天 7∶0 0 ,于第 2天 0∶0 0、1 6∶0 0和第 3天 0∶0 0分别服用莫达芬尼 2 0 0mg或安慰剂 ,采用随机双盲给药 ,并在第 1天 2 1∶0 0及每次服药后 1h、3h、5h、7h各完成 1次测试 ,内容包括 :1 )声、光刺激运动反应时 ;2 )注意分配 ;3)临界闪光融合频率 (criticalflickerfusionfre quency ,CFF) ;4) .斯坦福嗜睡量表 (stanfordsleepinessscale ,SSS) ;5 )自认疲劳分级表 (ratingofper ceivedexertion ,RPE)。结果与安慰剂组比较 ,第 2、3次服用莫达芬尼后CFF值较安慰剂组明显升高 ,斯坦福量嗜睡表、RPE表分值较安慰剂组明显下降 ;声、光刺激运动反应时与注意分配无明显变化。结论莫达芬尼能明显降低SD条件下的疲劳感和困倦程度

OBJECTIVE:To study the influence of ciprofloxacin on the pharmacokinetics of tacrolimus,so as to help the rational administration in clinical practice.METHODS:Ten New Zealand male rabbits were divided into two groups at random.Each animal of one group was administered iv,ciprofloxacin 30min after p.o. one tacrolimus capsule,the another group only p.o. one tacrolimus capsule as control group.The crossover experiment was done after a 2-week washout period.The whole blood concentrations of tacrolimus were...

OBJECTIVE:To study the influence of ciprofloxacin on the pharmacokinetics of tacrolimus,so as to help the rational administration in clinical practice.METHODS:Ten New Zealand male rabbits were divided into two groups at random.Each animal of one group was administered iv,ciprofloxacin 30min after p.o. one tacrolimus capsule,the another group only p.o. one tacrolimus capsule as control group.The crossover experiment was done after a 2-week washout period.The whole blood concentrations of tacrolimus were determined by ELISA,and the differences of pharmacokinetic parameters between two groups were compared.RESULTS:The pharmacokinetic parameters of tacrolimus alone and combined with ciprofloxacin were Cmax=(29.8±9.06),(27.9±8.32)ng/ml;T1/2β=(11.6±4.57),(12.8±3.78)h,AUC=(251.0±78.3),(265.7±74.6)ng/(ml·min),respectively.But no significant difference was found between two groups(P>0.05).CONCLUS_ION:The present study in rabbits showed no significant interaction between ciprofloxacin and tacrolimus after combined administration of these two drugs in a single dose.

目的 :研究环丙沙星在兔体内对他克莫司药代动力学的影响 ,为临床合理用药提供参考。方法 :10只兔子随机分成两组 ,一组口服他克莫司胶囊 ,30min后静脉注射环丙沙星 ;另一组仅口服他克莫司胶囊 ,2wk后交叉给药。给药后分别于不同时间点取血 ,用ELISA法测定药物浓度 ,计算药代动力学参数。结果 :单用和与环丙沙星合用的他克莫司药代动力学参数分别为 :Cmax=(29 8±9 06)、(27 9±8 32)ng/ml ,T1/2β= (11 6±4 57)h、(12 8±3 78)h ,AUC= (251 0±78 3)、(265 7±74 6)ng/(ml·min) ;经检验 ,两者均无显著性差异 (P>0 05)。结论 :单剂量的环丙沙星在兔体内对他克莫司的药代动力学无显著影响。

Aim To study the bioequivalence of aspirin-dipyridomole compound sustained-release tablets.Methods The bioavailability of the test preparation and foreign reference preparation in the dogs were determined and assessed by HPLC.In the crossover experiment designed study,the plasma in the six dogs was determined and the bioequivalence was assessed by 6 factors analysis of variance and two or one side test.Results The results showed that the relativity between the release extent in vitro and absorption percent...

Aim To study the bioequivalence of aspirin-dipyridomole compound sustained-release tablets.Methods The bioavailability of the test preparation and foreign reference preparation in the dogs were determined and assessed by HPLC.In the crossover experiment designed study,the plasma in the six dogs was determined and the bioequivalence was assessed by 6 factors analysis of variance and two or one side test.Results The results showed that the relativity between the release extent in vitro and absorption percent in vivo were good.The aspirin-dipyridomole sustained-release tablets were no distinct discrepancy in the absorption comparing to the foreign reference preparation.Conclusion The preparation and reference preparation have the same absorption extent.

目的 考察复方阿司匹林 /双嘧达莫缓释片生物等效性。方法 采用高效液相色谱法 ,对受试样品 (复方阿司匹林 /双嘧达莫缓释片 )及国外参比制剂Aggrenox (复方阿司匹林 /双嘧达莫缓释胶囊 )进行了家犬生物利用度对照研究。采用交叉实验设计 ,对 6条健康家犬体内血药复方阿司匹林 /双嘧达莫缓释片浓度进行实际测定 ,采用三因素方差分析及双单侧检验进行生物等效性研究。结果 自制复方阿司匹林 /双嘧达莫缓释体内外相关 ,并与参比制剂生物等效。结论 研制的复方阿司匹林 /双嘧达莫缓释片具有一定的开发价值。

 
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