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oral
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  口服液
    Study of DiGan Oral Liquid on Mechanism of Action for Leulcopenia in Micelnjured by Radiation and Chemistry
    地甘口服液对小鼠受辐射和化学损伤致白细胞减少症保护作用机理的研究
短句来源
    Study on Pharmacodynamics and Quality Control Methods of Xinshu Oral Liquid by Using Capillary Electrophoresis
    心舒口服液的高效毛细管电泳质量控制方法及药效学研究
短句来源
    The Effect of Dihuang Guanshitong Oral Liquid on the Esophagus Carcinoma Cell Apoptosis and β-catenin and c-myc of Wnt Pathway
    地黄管食通口服液对食管癌细胞凋亡及Wnt通路β-catenin和c-myc的影响
短句来源
    Study on Pharmacodynamic Action of Xiaochaihu Oral Liquid(Radix Bupleuri)
    小柴胡汤口服液药效作用的研究
短句来源
    Study on Quality Control Method for Renshensinitang Oral Liquid(Radix Ginseng,Radix Aconiti Praeparata,etc.)
    人参四逆汤口服液质量控制方法的研究
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  “oral”译为未确定词的双语例句
    Oral LD_(50) of TNT and Its Specific Damage to the Liver in Rats
    TNT对大鼠LD_(50)及肝脏特异病变观察
短句来源
    DETERMINATION OF TANNIN IN DUOYEYANNING ORAL LIQUID
    “多叶咽宁口含液”中鞣酸含量测定方法探讨
短句来源
    Experimental Study of Oral Use of Zheng Mai Liquor In Rabbits With Hemorrhaglc Shock
    整脉液抗兔失血性休克的实验观察
短句来源
    Effect of Composite Jiannao Oral Liquor(复方健脑液)on Cerebral Monoamine Neurotransmitter in Reserpinified Growth Period in Mice
    复方健脑液对利血平化发育期小鼠脑内单胺类神经递质的影响
短句来源
    STUDY ON QUALITY STANDARD OF RONGYANBULAO ORAL LIQUID
    容颜不老液的质量标准研究
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  oral
Pre-clinical studies were carried out (N=3) by oral, intramuscular and intravenous routes, while clinical studies (N=13) were performed intramuscularly.
      
5-FU-PT was given to rats by oral administration at a dosage of 22.5?mg kg-1.
      
Immure response induced by oral DNA vaccination against FMDV delivered by attenuated Salm onella choleraesuis C500
      
Specific immune response to this recombinant strain was evaluated by oral administration of the recombinant live bacteria pBO1/S.
      
The sequence of fetation might have appeared on the corolliform oral region of Punctatus emeiensis.
      
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1. Most of the pigeons vomitted to intravenous α-,β-,γ-Dichroines(alkaloids of Ch'ang Shan),intravenous digitoxin, and oral copper sulfate; a large number vomitted within 30 mins., a few between 1/2 to 2 1/2 hrs. and the rest after 2 1/2 hrs. 2.Chlorpromazine could decrease the 30 mins.—emetic—rate of pigeons by the three dichroines, digitoxin and copper sulfate. As a matter of fact, it did not'abolish the emetic actions induced by these emetics, but merely delayed their action. 3. The mechanism of vomiting...

1. Most of the pigeons vomitted to intravenous α-,β-,γ-Dichroines(alkaloids of Ch'ang Shan),intravenous digitoxin, and oral copper sulfate; a large number vomitted within 30 mins., a few between 1/2 to 2 1/2 hrs. and the rest after 2 1/2 hrs. 2.Chlorpromazine could decrease the 30 mins.—emetic—rate of pigeons by the three dichroines, digitoxin and copper sulfate. As a matter of fact, it did not'abolish the emetic actions induced by these emetics, but merely delayed their action. 3. The mechanism of vomiting by the dichroines and digitoxin is discussed.

(一) 靜脉注射常山碱甲,乙,丙,洋地黃毒苷及口服硫酸銅能引起大部分鴿子嘔吐,多数是在30分鐘內催吐的,也有一部分在1/2—2 1/2小时間嘔吐,另有少数鴿子的催吐潜伏期超过2 1/2小时。 (二) 氯丙嗪使常山碱甲,乙,丙,洋地黃毒苷及硫酸銅在30分鐘內的鴿催吐率降低。实际上氯丙嗪并不能阻止上述各种催吐药的鴿催吐作用,它仅仅是把催吐作用推迟一些,即延長催吐的平均潜伏期。 (三) 本文又探討了常山碱及洋地黄毒苷鴿催吐作用的机制問題。

1.Twenty-two agents were tested in vitro, and four of them also in vivo for their antituber- culous activity. 2.Ginkgolic.acid,the active principle of ginkgo fruit against tubercle bacilli,was found to exist only in the fleshy part(endocarp)of the fruit.The tuberculostatic action of ginkgolic acid in vitro was not influenced by heating,but the presence of serum raised the minimal effec- tive concentration from 1:400,000 to 1:1000.The results of in vivo tests failed to demonstrate any effect of the different...

1.Twenty-two agents were tested in vitro, and four of them also in vivo for their antituber- culous activity. 2.Ginkgolic.acid,the active principle of ginkgo fruit against tubercle bacilli,was found to exist only in the fleshy part(endocarp)of the fruit.The tuberculostatic action of ginkgolic acid in vitro was not influenced by heating,but the presence of serum raised the minimal effec- tive concentration from 1:400,000 to 1:1000.The results of in vivo tests failed to demonstrate any effect of the different parts of ginkgo fruit in- cluding ginkgolic acid on the experimental tuber- culosis of mice.No apparent difference was found between the activity of ginkgo fruit with or without previous preparation with vegetable oil. 3.(?)In vitro,garlic exhibited rather weak tuberculostatic action,which decreased slightly in thè presence of serum.The in vitro effect of the winter garlic was better than that of the spring one.No curative effect was exerted by garlic on the experimental tuberculosis of mice. 4.The minimal tuberculostatic concentra- tion of berberine in vitro was found to be around 1:4000,and the èffect slightly decreased in the presence of serum.The development of experi- mental tuberculosis of mice was delayed by the administration of berberine sulfate in daily oral doses of 1.5—2.5 gm./kg. 5.There was definite curative effect of stepharanthine on the experimental tuberculosis of mice in daily doses of 200 mg./kg.;significant toxicity appeared,however,at that dosage level. 6.No significant tuberculostatic effect in vitro was found among other crude drugs. 7.“Hei pao”was ineffective in vitro,while citrinin was definitely effective and its minimal tuberculostatic concentration determined as 1:20.000. 8.Amon synthetic compounds tested,the in vitro tuberculostatic potency of an isomer of PAS was only one-hundredth of that of sodium para- amino-salicylate.The tuberculostatic effects of four sulfones were not satisfactory.The minimal tuberculostatic concentration in vitro of syn- thotic compound Ⅵ was 1:200,000. 9.It was found that the effectlve ranges of the concentration and dosage of thiosemicarba- sone in viro and in vivo were very broad,and the lower margins were comparable with those of isonicotinyl hydrazine.These facts may explain the elinieal effectiveness of thiosemicarbazone used in small doses.

1.在玻器内试验了22种药物,在动物体内试验了四种药物的抗结核杆菌作用。2.白果的抗结核杆菌有效成分(白果酸)仅存在于白果果浆中。白果酸在玻器内的抗菌作用不受加热的影响;但血清能使其最低有效浓度从1:400,000跃至1:1000。白果各部分及白果酸对小鼠的实验结核症并无肯定的疗效。油浸过的白果与未浸过的作用并无显著不同。3.大蒜在玻器内具有较弱的抗结核杆菌作用,遇血清则效力略减;冬季大蒜比春季大蒜的效力高。对小鼠的实验结核症并无疗效。4.黄连硷在玻器内的最低抑制结核杆菌浓度是1:4000左右,遇血清则效力略减。每日食入硫酸黄连硷约1.5—2.5克/公斤时,可以延缓小鼠实验结核症的发展。5.使他肺安定每日200毫克/公斤时,对小鼠实验结核症有肯定的疗效,但已表现相当大的毒性。香豆素在玻器内当浓度为1:2000时有部分抗结核杆菌作用。6.其他生药中,仅韭菜及青蒜在修改的都氏培养基中具有微弱的抗结核杆菌能力,但在尤氏培养基中无效。7.海宝在玻器内无效,橘霉素的最低制菌浓度是1:20,000。8.所试的化学合成品中,对氨水杨酸的同质异构物的抗结核杆菌作用仅为对氨水杨酸钠的1/100。砜类化合物的抗结核杆菌作用很微弱...

1.在玻器内试验了22种药物,在动物体内试验了四种药物的抗结核杆菌作用。2.白果的抗结核杆菌有效成分(白果酸)仅存在于白果果浆中。白果酸在玻器内的抗菌作用不受加热的影响;但血清能使其最低有效浓度从1:400,000跃至1:1000。白果各部分及白果酸对小鼠的实验结核症并无肯定的疗效。油浸过的白果与未浸过的作用并无显著不同。3.大蒜在玻器内具有较弱的抗结核杆菌作用,遇血清则效力略减;冬季大蒜比春季大蒜的效力高。对小鼠的实验结核症并无疗效。4.黄连硷在玻器内的最低抑制结核杆菌浓度是1:4000左右,遇血清则效力略减。每日食入硫酸黄连硷约1.5—2.5克/公斤时,可以延缓小鼠实验结核症的发展。5.使他肺安定每日200毫克/公斤时,对小鼠实验结核症有肯定的疗效,但已表现相当大的毒性。香豆素在玻器内当浓度为1:2000时有部分抗结核杆菌作用。6.其他生药中,仅韭菜及青蒜在修改的都氏培养基中具有微弱的抗结核杆菌能力,但在尤氏培养基中无效。7.海宝在玻器内无效,橘霉素的最低制菌浓度是1:20,000。8.所试的化学合成品中,对氨水杨酸的同质异构物的抗结核杆菌作用仅为对氨水杨酸钠的1/100。砜类化合物的抗结核杆菌作用很微弱。合成品〔Ⅵ〕的最低制菌浓度是1:200,000。9.硫脲胺的部分制菌浓度范围和其对小鼠实验结核症有效剂量的范围都很广,可以追及异烟肼的水平,这可解释临床上其剂量很小,但仍能生效的原因。

The LD_(50) in mice was found to be 19.4 g/kg and 0.98±0.075 g/kg respectively for the infusion and crude extract of Chou-wu-tung, given by intravenous injections. The subacute toxicity is negligible when the infusion was crally administered to rats (0.25—2.5 g/kg/day) for 60 days, except that some animals showed quietness, slight fall of systolic pressure and soft stool. No apparent toxic effects were observed. A crude extract and infusion of Chou-wu-tung, when injected intravenously at respective dosages...

The LD_(50) in mice was found to be 19.4 g/kg and 0.98±0.075 g/kg respectively for the infusion and crude extract of Chou-wu-tung, given by intravenous injections. The subacute toxicity is negligible when the infusion was crally administered to rats (0.25—2.5 g/kg/day) for 60 days, except that some animals showed quietness, slight fall of systolic pressure and soft stool. No apparent toxic effects were observed. A crude extract and infusion of Chou-wu-tung, when injected intravenously at respective dosages of 50—100 mg/kg and 150 mg/kg, produced primary and secondary falls of blood pressure on anaesthetized rats and dogs, but with intramuscular injection or oral administration, only the secondary fall of blood pressure was apparent. This hypotensive effect might last for 2—3 hours. Intravenous injection of the decoction to anaesthetized animals produced only primary fall of blood pressure, the infusions of alcohol, ether and ,chloroform, given by the same route, did not lower the blood pressure. Twenty-eight renal hypertensive rats were divided into three groups, the first (11 rats) and the second (7 rats) groups were treated with the infusion at respective dosages of 0.5 g/kg/day and 5 g/kg/day, and the third (10 rats) with the crude extract at 50 mg/kg/day. The drug was given to all the rats for 2 weeks by oral administration. Hypotensive effect was observed in 3—10 days after medication, and became more remarkable in the second week of the therapeutic period or the first week after cessation of medication; the blood pressure dropped 57.4%. The blood pressure in most rats returned in 2 weeks, and in some rats in 2—4 days or 4 weeks after the stopping of medication.

1.本文就臭梧桐的一般性质作了实验性研究,结果证明其降血压成分易溶于水,难溶或不溶于乙醚、乙醇和氯仿,对热稳定,在碱性溶液中可被氯化钙沉淀出来。臭梧桐降血压效果可因产地而不同。开花前的和新鲜的臭梧桐降血压作用分别较开花后的和经长时间保存的要强。 2.臭梧桐毒性甚小,其热浸剂和提出物给小鼠静脉注射时半数致死量分别为19.4克/公斤和0.98±0.075克/公斤。给大鼠每天用热浸剂(0.25—2.5克/公斤)灌胃经60天,除少数动物出现安静、轻度收缩压下降和大便变稀外,未发现其他毒性反应。 3.臭梧桐提出物(50—100毫克/公斤)和热浸剂(150毫克/公斤)给麻醉大鼠和狗静脉注射时,可引起两度血压下降,但肌肉注射或经口给药,仅引起第二度降血压作用,其作用可维持2—3小时。静脉注射煎剂(麻醉大鼠和狗实验)仅出现第一度降血压作用,经口给药时无效。乙醚、乙醇和氯仿的浸出液不论静脉注射或经口给药,均不引起麻醉动物的血压下降。给肾型高血压大鼠每天经口投予臭梧桐热浸剂(0.5—5克/公斤)和提出物(50毫克/公斤)时,给药的第3—10天卽口出现血压下降,在给药的第二周和停药后的第一周,血压下降最明显,最大降血压作用可达原值...

1.本文就臭梧桐的一般性质作了实验性研究,结果证明其降血压成分易溶于水,难溶或不溶于乙醚、乙醇和氯仿,对热稳定,在碱性溶液中可被氯化钙沉淀出来。臭梧桐降血压效果可因产地而不同。开花前的和新鲜的臭梧桐降血压作用分别较开花后的和经长时间保存的要强。 2.臭梧桐毒性甚小,其热浸剂和提出物给小鼠静脉注射时半数致死量分别为19.4克/公斤和0.98±0.075克/公斤。给大鼠每天用热浸剂(0.25—2.5克/公斤)灌胃经60天,除少数动物出现安静、轻度收缩压下降和大便变稀外,未发现其他毒性反应。 3.臭梧桐提出物(50—100毫克/公斤)和热浸剂(150毫克/公斤)给麻醉大鼠和狗静脉注射时,可引起两度血压下降,但肌肉注射或经口给药,仅引起第二度降血压作用,其作用可维持2—3小时。静脉注射煎剂(麻醉大鼠和狗实验)仅出现第一度降血压作用,经口给药时无效。乙醚、乙醇和氯仿的浸出液不论静脉注射或经口给药,均不引起麻醉动物的血压下降。给肾型高血压大鼠每天经口投予臭梧桐热浸剂(0.5—5克/公斤)和提出物(50毫克/公斤)时,给药的第3—10天卽口出现血压下降,在给药的第二周和停药后的第一周,血压下降最明显,最大降血压作用可达原值的57.4%。多数高血压大鼠的血压在停药后的第二周恢复,少数在停药的2—4天或4周后恢复。

 
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