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narcotics
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  麻醉药品
     Analysis of narcotics uses in our hospital in the period of 2001-2004
     2001-2004年我院麻醉药品应用分析
短句来源
     Analysis of Narcotics Used in Hospitals of Guangdong Province During the Period 2002~2004
     2002年~2004年广东地区医院麻醉药品应用分析
短句来源
     Analysis of Narcotics Used in Our Hospital During the Years 2001~2003
     2001~2003年我院麻醉药品应用情况分析
短句来源
     Analysis of Narcotics Used in Our Hospital During the Period 2000~2002
     2000年~2002年我院麻醉药品应用分析
短句来源
     Strict management methods of narcotics
     麻醉药品的严格管理方法
短句来源
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  毒品
     26.4% arrested by police,22.5% selled narcotics,36%(9/25) had sexual behavior with others for narcotics,15.5% stole,robbed,cheated in the past six months.
     在过去的6个月中,26.4%被公安抓过,22.5%贩卖过毒品; 36%(9/25)为了毒品和别人发生过性行为,15.5%为了吸毒而有偷、抢、骗。
短句来源
     GC/MS to Test Narcotics Composition in the Hemp Plant
     GC/MS法检测大麻植物中的毒品成分
短句来源
     X-ray Diagnosis of Concealment of Narcotics in the Body
     体内藏匿毒品的X线诊断
短句来源
     The cultural countermeasurews of preventive narcotics should be to strengthen the construction of cultures and a system of control to the flowing people in the district and to bulid harmonious community.
     预防该区毒品犯罪的文化对策应是大力发展当地教育、加强社区的文化和人口流动监控系统等建设,消除毒品犯罪的内在文化根源和外在诱发因素,构建和谐社区。
短句来源
     Studies of Narcotics by Micro Raman Spectroscopy
     显微拉曼技术对毒品检测分析的研究
短句来源
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  麻醉品
     In reverse, Federal government impels states’ marijuana laws formation and unification by Federal Bureau of Narcotics.
     反过来,联邦政府通过联邦麻醉品局的活动又推动了州大麻法的出台和统一。
短句来源
  “narcotics”译为未确定词的双语例句
     for the type of narcotics:meperidines 39.6%, morphine 57.1%;
     对病人使用药物种类:哌替啶39·6%,吗啡57·1%;
短句来源
     The total positive rate of narcotics was 55.35%.
     结果经监测检出吸毒阳性1096例,阳性率55.35%。
短句来源
     ③ At the second day after stopping using narcotics, the rats in Quqianling group were treated with gastric perfusion of the corresponding type solution at the dosage of 10 μL/g Chinese compound Quqianling with once a day and at the 11th day stopped for one day totally for 3 weeks.
     ③停止染毒后第2天,驱铅灵各组分别用相应剂型的中药复方驱铅灵10μL/g体质量灌胃,1次/d,第11天停1d,共3周。
短句来源
     Postoperative incision pain was recorded by VAS(visual analogue scales) including recording the dosage of narcotics, pulmonary function on 3, 7, 15, 30, 90 postoperative days.
     两组患者分别于术后第 3,7,15 ,30 ,90天测定肺功能。
短句来源
     All patients were treated for 6 to 8 weeks,type ⅢA with antibiotics and α 1 receptor inhibitor,type ⅢB with α 1 receptor inhibitor,diazepam diclogenatis and other narcotics.
     综合性治疗 6~ 8周。 ⅢA型患者以广谱抗生素及α1受体阻滞剂治疗为主 ,ⅢB型则分别给予α1受体阻滞剂、镇静剂、镇痛肌松剂治疗 ;
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  narcotics
Conditions of the simultaneous separation of most familiar narcotics by HPLC on one column with high precision and low detection limit were optimized.
      
Rapid Determination of Explosives and Narcotics Using a Multicapillary-Column Gas Chromatograph and an Ion-Mobility Spectrometer
      
A Thermal-Desorption Surface-Ionization Indicator of Narcotics and Other Drug Preparations
      
The results of the development of a new method and instrument for determining trace narcotics and other abused drugs in extracts of biological samples (urine, blood, and postmortem specimens) from users of the above substances are reported.
      
A narcotics case register - Some perspective on multiple reports
      
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(1) The sciatic and medial nerves are stimulated by rectangular impulses with. a definite strength and duration(so called etectro acupuncture), and a narcotic state of animal is induced within 20-30 minutes, during which the animal shows no response to nociceptive stimuli. (2) The blood pressure rises immediately after, the application of electroacuptuncture, and then retnrns to about control level although the electro-acupuncture lasts. with the withdrawal of etecfro-acu Punoture, the bood pressure is...

(1) The sciatic and medial nerves are stimulated by rectangular impulses with. a definite strength and duration(so called etectro acupuncture), and a narcotic state of animal is induced within 20-30 minutes, during which the animal shows no response to nociceptive stimuli. (2) The blood pressure rises immediately after, the application of electroacuptuncture, and then retnrns to about control level although the electro-acupuncture lasts. with the withdrawal of etecfro-acu Punoture, the bood pressure is completely recovered, it is therefore shown that electro-acuPuncture does not exert undesirable action on the cardiovascular system. (3) The pressor reflex caused by occlusion of carotid artery shows an exaggeration during the course of elect ro-acupuncture and restores to control leel as the electro- acupuncture is discontinued. (4) During the course of electroacupuneture, the pressor reflex elicited by stimulation of central end of depressor nerve with various strength of Fa adic curreut reveals typical phasic changes of Wedensky s parabiotic inhibition. (5) On the basis of above observations it is suggested that the physiological mechanism of the electro-acupunetare narcosis is the development of parabiosis in the nerve centers as the consequence of prolonged actionof afferent impules from eletroacupuncture regions.

(一)用一定强度和时间的电针刺激家兔,能引起动物的麻醉状态,使动物对一般损伤性刺激不出现反应;停止电针后10——15分钟,动物对损伤性刺激的反应恢复。 (二)动脉血压在电针刚开始时突然增高,随后恢复至接近正常水平,电针停止后血压完全恢复,由此表明电针本身对心臟——血管系统并无不良影响。 (三)阻塞一侧颈总动脉所致的加压反射,在电针过程中表现加强,电针停止后又恢复正常。 (四)以感应电刺激减压神经向中段所致的减压反射,在电针过程中有特異性变化,表现为减压神经强刺激引起的减压效应较针前为弱,而弱刺激的效应反较针前为强,并出现了均等和反常的间生性效应。 (五)从本实验的结果来看,电针麻醉的机制是在于电针刺激的大量冲动,引起了神经中枢间生态的发展,并且这种发展取决于电针刺激的强度和时间,而在各动物之间有一定的个体差異。

The methyl-eugenol is an active principle isolated from the essential oil of Asarum forbesii Maxium. Pharmacological studies showed that methyl-eugenol had marked depressant effect on central nervous system.It was found to potentiate the hypnotic action of pentobarbital and thiopental and the central depressant effect of chlorpromazine. When injected intravenously, methyleugenol showed narcotic effect in rabbits, cats, dogs and monkeys. It caused disappearence of righting-reflex, pain sensation and hearing...

The methyl-eugenol is an active principle isolated from the essential oil of Asarum forbesii Maxium. Pharmacological studies showed that methyl-eugenol had marked depressant effect on central nervous system.It was found to potentiate the hypnotic action of pentobarbital and thiopental and the central depressant effect of chlorpromazine. When injected intravenously, methyleugenol showed narcotic effect in rabbits, cats, dogs and monkeys. It caused disappearence of righting-reflex, pain sensation and hearing reflex and slowness of corneal reflex. Average narcotic time with methyl-eugenol varied with different species; rabbits (50mg/kg)13.9, cats (50mg/kg) 9.0; dogs (40mg/kg) 25.0, and monkeys (80mg/kg) 30/0 minutes. It also exhibited marked inhibition of the spontaneous E E G of the cortex and mid-brain RF.Methyl-eugenol exhibited slight depressant action on the cardiovascular system and decrease of blood pressureby 20~30 mmHg in cats and lowering of body temperature in rats.Rapid administration of the drug or overdosage brought about depressant action on respiration (decreased in frequency or even stopp) but it may quickly recover.It may be concluded that methyl-eugenol possesses narcotic action which is similar to commonly used short-acting anaesthetics.

甲基丁香酚(metliyl eugenol)为马辛(Asarum forbesii Maxim)挥发油提得的一个纯品,具有明显的中枢抑制作用:(1)协同中枢抑制药的效应;(2)对多种动物均能产生麻醉作用,且随着剂量变化而麻醉时间长短不同;(3)能抑制免大脑皮层及中脑网状结构的自发脑电活动。此外,给药过快或剂量过大可出现呼吸减慢或停止,但能迅速恢复。持续给药1~2小时或多次给药后进行血象、肝肾功能及各脏器的病理切片等检查,结果除白细胞略有上升外其它均属正常。

A new potent narcotic analgesic, N-[1-(β-hydroxy β-phenylethyl)-3-methyl-4-piperidyl]-N-phenylpropionamide (simply named as F-7302) was labelled by tritiumhalogen exchange and catalytic reduction of N-[1-(p-bromo-benzoyl methyl)-3-methyl-4-piperidyl]-N-phenylpropionamide with tritium gas, using PdO/BaSO_4 as catalyst, removal of labile tritium by treating with alcohol, and final purification with silica-gel paper chromatography. Methyl orange was employed for the quantitative determination of [~3H] F-7302....

A new potent narcotic analgesic, N-[1-(β-hydroxy β-phenylethyl)-3-methyl-4-piperidyl]-N-phenylpropionamide (simply named as F-7302) was labelled by tritiumhalogen exchange and catalytic reduction of N-[1-(p-bromo-benzoyl methyl)-3-methyl-4-piperidyl]-N-phenylpropionamide with tritium gas, using PdO/BaSO_4 as catalyst, removal of labile tritium by treating with alcohol, and final purification with silica-gel paper chromatography. Methyl orange was employed for the quantitative determination of [~3H] F-7302. The specific radioactivity was 59 ci/mM, and the radiochemical purity was 98%.[~3H] F-7302 binding experiments with opiate receptors of mouse brain showed a high affinity and specificity. The saturation concentration for the stereospecific binding of [~3H]F-7302 was 4.5×10~(-9)M. and the dissociation constant was 1.25×10~(-9)M.The retio of specific/nonspecific binding was 10~15.

本文报道以N-[1-(对-溴苯甲酰甲基)-3-甲基-4-哌啶基]-N-丙酰苯胺(Ⅲ)为前体,以PdO/BaSO_4作催化剂,用氚气进行卤—氚置换,氚化还原羰基的反应。反应产物经硅胶纸层析纯化后,用甲基橙比色法定量测定,得到N-{1-[β-羟基-β-氚-β-(对-氚苯基)乙基]-3-甲基-4-哌啶基}-N-丙酰苯胺(Ⅳ,[~3H]F-7302),其比放射性为59 Ci/mM,放化纯度为98%。[~3H]F-7302与小鼠脑内阿片受体的特异性结合在浓度为4.5×10~(-9)M时达到饱和,解离常数Kd=1.25×10~(-9)M,最大结合量B_(max)=93.08×10~(12)M/g蛋白,其特异性结合与非特异性结合比值达10~15。

 
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