The test with the marker Phi057 revealed that the segregation ratio of two genotypes, o2o2 and O2o2, in the BCiF, families of (CA335×Huangzao4) ×CA335 with 224 individuals was 1:1.24 as it was expected according to Mendelian segregation.
Objective Congenital fibrosis of the extraocular muscles (CFEOM) is a kind of syndrom following Mendelian inheritance. In our study,eight short tandem repeat(STR) loci including D12S1048, D12S59, D12D331, D12S345 on chromosome 12 and D16S3026, D16S689, D16S3063, D16S3121 on chromosome 16 were chosen as DNA markers for linkage analysis.
目的 在先天性眼外肌纤维化(congenital fibrosis of the extraocular muscles CFEOM)的CFEOM1和CFEOM3位点,分别选择了位于12号染色体上D12S1048、D12S59、D12D331、D128345和位于16号染色体上的D1683026、D168689、D16S3063、D16S3121共8个STR多态标记进行连锁分析。
The personal identification was studied in Chinese of Han nationality by using six dinucleotide simple tandem repeat polymorphism loci that located in different chromosomes and showed Mendelian codominant inheritances. These six loci are: D1S103,D4S175, D5Sl07,D19S49,D6S89 and D9S58. The results showed;
The separation in F2 between the resistance and sensistive basically according 3:1, while in B1F1 generation is 1:1. The result showed that the inheritance of Bar gene was a single dominant gene and accorded with the law of Mendelian segregationbasically.