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trisomic
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  三体
     His father and uncle are carriers of the balanced translocation between chromosome 1 and 4. Both karyotypes of theirs are 46, XY, t(1;4) (lpter→1q43::4q25→4qter; 4pter→4q25::1q43→1qter). It is supposed that the trisomic segment 4q25→4qter of the infant originated from his father.
     其母亲核型正常,父亲和伯父核型均为46,XY,t(1;4)(1pter→1q43∷4q25→4qter;4pter→4q25∷1q43→1qter),认为患儿的4q部分三体片段(4q25→4qter)得自父亲。
短句来源
     By chromosome number observation, most progeny plants revealed aneuploids in which trisomic plants was 33.3% for 3x×2x and 40.70% for 2x×3x.
     经染色体数目检查 ,杂交子代植株绝大多数为非整倍体 ,其中三体植株占 33.3% (3x× 2x)和4 0 .70 % (2x× 3x)。
短句来源
     Trisomic types A, B, C, D, E and H were confirmed to have individual extra chromosomes K5, K6, K12, K7, K. 8 and K10 respectively.
     结果表明:A型、B型、C型、D型、E型和H型三体的额外染色体分别为K5、K6、K12、K7、K8和K10。
短句来源
     Conclusions were followed:1 Aneuploid line 9404-4-1 was designated as trisomic 3,line 9405-8 as trisomic 4,line 9405-9 as trisomic 5,line 9405-10 as trisomic 7,Iine 9405-11 as trisomic 10,line 9405-12 as monosomic 3,Iine 9405-13 as monosomic 5,line 9405-14 as monomic 6 and line 9405-15 as monosomic 10.2There were abnormal phenomenon during meiosis .
     1.通过有丝分裂中期核型分析,确定9405-8为4号三体、9405-9为5号三体、9405-10为7号三体、9405-11为随体三体、9405-12为3号单体、9405-13为5号单体、9405-14为6号单体、9405-15为随体单体。
短句来源
     The segregation ratio of fertility to sterility is 3∶1 in F_2 generation of trisomics 2, 3, 4, 5, 7, 8 and 9; and 14∶1 only in F_2 generation of trisomic 6 (χ2_ 0.05=0.012).
     结果是三体 3、5、7、8、9的F2 代分离出的可育株与不育株之比为 3∶1,三体 6的可育株与不育株之比为 14∶1(χ2 =0 .0 12 ,P =0 .0 1)。
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  三体的
     Trisomic types A, B, C, D, E and H were confirmed to have individual extra chromosomes K5, K6, K12, K7, K. 8 and K10 respectively.
     结果表明:A型、B型、C型、D型、E型和H型三体的额外染色体分别为K5、K6、K12、K7、K8和K10。
短句来源
     5. Pollen activity of trisomic 2,7,9 was lower than that of diploid significantly;
     5.9号三体的花粉活力显著低于二倍体; 2号、7号三体的花粉活力极显著低于二倍体;
短句来源
     6 Pollen development courses of trisomic 5 were normal.
     6 5号三体的花粉发育过程与二倍体相似,无异常现象。
短句来源
     Identification of the Double Trisomic and Its Primary Trisomics in Cabbage
     结球甘蓝1号和4号染色体双三体及其初级三体的分离与鉴定
短句来源
     Pollen activity of trisomic 7 was the lowest.
     7号三体的花粉活力最低。
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  “trisomic”译为未确定词的双语例句
     The results of chromosome analysis are as follows:1. Forty patients had the clinical and cytogenetic features of Down's syndrome, of which 36 were trisomic for chromosome 21 [47, XX(or XY), + 21]; 2 were translocation between D group and G group [46, XX, - D, +t(DqGq)]; 2 were translation between G group and G group [46, XX (or XY), - G, +t(GqGq)].
     先天愚型:第21染色体三体征[47,XX(或XY),+21]36例,D/G易位[46,XX,-D,+t(DqGq)]2例,G/G易位[46,XX(或XY),-G,+t(GqGq)]2例;
短句来源
     The karyotype of a group of root tip cells(2n=38) was analyzed and it was found that the sixth pair of chromosomes was trisomic; a univalent chromosome with one satellite was also found,its karyotype and karyotype formula were 2B and 2n=38=26m+8sm+1Ш+1Ι,respectively.
     对2n=38的一组根尖细胞的核型分析发现,第6对染色体为一个三价体,还发现一个单价体,且带有随体,其核型为2B,核型公式2n=38=26m+8sm+1Ш+1Ι。
短句来源
     2. 2 patients had trisomic 18 [47, XX, +18]. 3. 7 had large short arm of G group [46, XX (or XY), Gp +].
     第18染色体三体征[47,XX(或XY)+18]2例;
短句来源
     and 4 cases are No. 18 and 13 trisomic high risk which is 0.2% in the total. The confirmed diagnosis abnormal foefus is 9 cases, therein, 7 cases are chromosome abnormality, and 2 cases are rachischisis.
     18及13三体高风险4例,占0.2%,确诊异常胎儿9例,其中染色体异常7例,脊柱裂2例。
短句来源
     The karyotype of the mosaics was followed up regularly and found that there was a kinetic change of the proportion of the normal cells and 21 trisomic cells within the first year of life, and it tended to be stable after 2 years of age.
     对嵌合型定期进行了核型随访,发现在患儿1岁左右正常细胞与21三体细胞嵌合的比例呈动态变化,而在2岁以后则渐趋稳定。
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  trisomic
The cells carrying der(3)t(3;10) are monosomic for a proportion of 3p25 and trisomic for 10q24.3 → qter.
      
The chromosomal abnormalities were structural (34.4%) and numerical (65.1%) of which 26.1, 21.7, 8.7 and 8.7% were fetal sex aneuploid, triploid, mosaics and trisomic, respectively.
      
The induction of apoptosis by daunorubicin and idarubicin in human trisomic and diabetic fibroblasts
      
In this study, we investigated apoptosis induced in human trisomic and diabetic fibroblasts by daunorubicin (DNR) and its derivative, idarubicin (IDA).
      
Our findings also demonstrated that idarubicin was more cytotoxic and more effective than daunorubicin in inducing apoptosis in trisomic and diabetic fibroblasts.
      
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The paper presents in detail the technique of leucocytes culture from human peripheral blood for the study of human chromosomes. The techniques involve both the standard method and the semi-micro method with some modifications which have been developed in this laboratory to suit our purposes. With the aid of these techniques, cytogenetic analyses for 7 different cases belonging to 4 different types of congenital defects were made, and the main results are briefly described as follows:1. Down's syndrome (4 cases)....

The paper presents in detail the technique of leucocytes culture from human peripheral blood for the study of human chromosomes. The techniques involve both the standard method and the semi-micro method with some modifications which have been developed in this laboratory to suit our purposes. With the aid of these techniques, cytogenetic analyses for 7 different cases belonging to 4 different types of congenital defects were made, and the main results are briefly described as follows:1. Down's syndrome (4 cases). Most of the cells analyzed in each case showed 47 chromosomes, and the extra chromosome was found to be one of the smallest chromosome in the karyotype. This finding is apparently in agreement with trisomic G-type as previously reported in the literatures. It is highly probable that the origin of this aberration may arise from non-disjunction of one pair of the smallest chromosomes occured in o?genesis, since there is an indication in the rise of the frequencies of Down's syndrome with the age of the mother.2. Testicular feminization syndrome (1 case). The case reported here involves the finding of the same syndrome in 3 successive generations in one family. Chromosomal analysis was available from only one patient and the result demonstrated that most cells showed a chromosome number of 46 with the normal male XY complement, which was found to be in conformity with the discovery that the chromatin was negative on nuclear sexing. This finding is in obvious disagreement with XXY constitution as suggested by some authors to account for the clinical manifestations of this syndrome. Together with the reports of some other workers, analysis of the familial history of the case gives further evidence in support of the suggestion by Grumbach and Barr that this syndrome may be inherited as due to either a sex-linked recessive or a sex-limited dominant factor, though the existing genetic evidence does not suffice to distinguish between the two possibilities.3. Anorchism (1 case). Chromosome analysis of the patient in question revealed the diploid chromosome number to be 46, including an X and a Y chromosome. The nuclear chromatin pattern was also demonstrated to be of male type. Since this case was a sporadic one, it could be assumed to have been originated by mutation. 4. Female pseudohermaphroditism (1 case). A preliminary analysis of the patient revealed the possibility of being an XO(45)/XY(46) mosaic. But this can not be ascertained without further verification from the observations on the skin and bone marrow cultures.

本文详细地介绍了以外周血液培养来研究人类染色体的技术,这些都是我们实验室几年来根据国外文献作了一些修改,以适合于我们的具体条件而拟订的.同时应用这些方法对若干病例作了细胞遗传学的研究,主要结果如下:1.四例先天愚型:在这些病例中,绝大多数中期细胞的染色体数均为47.核型分析表明为G-三体型.一般认为这是由于母亲在卵细胞形成时发生了染色体不分离的结果.2.睾丸女性化:这里报导了一个很大的家系,这一综合症的患者在该家系中已络续出现了三代.其中的一个病人用于白细胞的染色体研究.结果是正常人的双倍体数(2n=46), 具有正常男性的核型,即XY.口腔粘膜及多形核嗜中性球的性染色质扦查为阴性.这种结果显然不符合于这样的假设,即认为该种综合症的性染色体组成是XXY.结合以往一些作者的研究,我们认为该综合症是以伴性隐性或限性的常染色体显性而遗传的.但从现有证据尚不足以区分这两种的可能性.3.无睾畸形:白细胞的双倍体数为2n=46,显示正常的男性核(XY).性染色质为阴性.鉴于该病例为散发性的,我们认为它有可能起因于基因突变.4.女性假两性畸形:由白细胞的初步分析,认为可能是XO(45)/XY(46)嵌合体.但为了肯定其确切...

本文详细地介绍了以外周血液培养来研究人类染色体的技术,这些都是我们实验室几年来根据国外文献作了一些修改,以适合于我们的具体条件而拟订的.同时应用这些方法对若干病例作了细胞遗传学的研究,主要结果如下:1.四例先天愚型:在这些病例中,绝大多数中期细胞的染色体数均为47.核型分析表明为G-三体型.一般认为这是由于母亲在卵细胞形成时发生了染色体不分离的结果.2.睾丸女性化:这里报导了一个很大的家系,这一综合症的患者在该家系中已络续出现了三代.其中的一个病人用于白细胞的染色体研究.结果是正常人的双倍体数(2n=46), 具有正常男性的核型,即XY.口腔粘膜及多形核嗜中性球的性染色质扦查为阴性.这种结果显然不符合于这样的假设,即认为该种综合症的性染色体组成是XXY.结合以往一些作者的研究,我们认为该综合症是以伴性隐性或限性的常染色体显性而遗传的.但从现有证据尚不足以区分这两种的可能性.3.无睾畸形:白细胞的双倍体数为2n=46,显示正常的男性核(XY).性染色质为阴性.鉴于该病例为散发性的,我们认为它有可能起因于基因突变.4.女性假两性畸形:由白细胞的初步分析,认为可能是XO(45)/XY(46)嵌合体.但为了肯定其确切的核型,还有待于对病者的皮肤和骨髓作进一步的研究.

One hundred and fifty-five children in Peking with mental retardation were examined karyologically with the aid of peripheral blood culture techniques. A total of 74 patients were found to have abnormal karyotypes. The results of chromosome analysis are as follows:1. Forty patients had the clinical and cytogenetic features of Down's syndrome, of which 36 were trisomic for chromosome 21 [47, XX(or XY), + 21]; 2 were translocation between D group and G group [46, XX, - D, +t(DqGq)]; 2 were translation between...

One hundred and fifty-five children in Peking with mental retardation were examined karyologically with the aid of peripheral blood culture techniques. A total of 74 patients were found to have abnormal karyotypes. The results of chromosome analysis are as follows:1. Forty patients had the clinical and cytogenetic features of Down's syndrome, of which 36 were trisomic for chromosome 21 [47, XX(or XY), + 21]; 2 were translocation between D group and G group [46, XX, - D, +t(DqGq)]; 2 were translation between G group and G group [46, XX (or XY), - G, +t(GqGq)].2. 2 patients had trisomic 18 [47, XX, +18].3. 7 had large short arm of G group [46, XX (or XY), Gp +].4. 1 had translocation of long arm in E group chromosome [46, XY, Eq+].5. 1 had large short arm of a D group [46, XX, Dp + ].6. 1 had translocation of long arm in a G group [46, XY, Gq+].7. 1 had an extra small chromosome of the G group [47, XY, + Gq - ].8. 21 had large Y chromosome [46, XYq+].9. 81 had normal chromosome complements [46, XX (or XY)].The clinical and cytogenetic characteristics of the patients were discribed, the relationships between chromosomal abnormality and mental retardation were discussed.

本文应用染色体组型分析法,研究了155例先天性大脑发育不全儿童的染色体,分析结果可以分成如下几种类型。先天愚型:第21染色体三体征[47,XX(或XY),+21]36例,D/G易位[46,XX,-D,+t(DqGq)]2例,G/G易位[46,XX(或XY),-G,+t(GqGq)]2例;第18染色体三体征[47,XX(或XY)+18]2例;E组染色体长臂易位(46,XY,Eq+)1例;G组长臂易位(46,XY,Gq+)1例;一个额外的G组小染色体(47,XY,+Gq-)1例;此外还有大Y染色体(46,XYq+)21例;G组短臂增大[46,XX(或XY),Gp+]7例;D组短臂增大(46,XX,Dp+)1例。有染色体改变者共74例,未见染色体改变者81例。染色体组型分析可以作为大脑发育不全等遗传疾病诊断的工具之一。

Primary trisomic is one of the most important genetic tester in crops.The following aspects concerning primary trisomics in rice have been reviewed by the author: (1)sources; (2) morphological classification; (3) cytogenetics and ( 4 ) application to genetical researches.A complete set of primary trisomics in Hsien rice (i.e. Indica rice ) has been established both morphologically and cytologically by IRRI in 1975.All eleven types of primary trisomics except the pseudonormal one can be distinguished from...

Primary trisomic is one of the most important genetic tester in crops.The following aspects concerning primary trisomics in rice have been reviewed by the author: (1)sources; (2) morphological classification; (3) cytogenetics and ( 4 ) application to genetical researches.A complete set of primary trisomics in Hsien rice (i.e. Indica rice ) has been established both morphologically and cytologically by IRRI in 1975.All eleven types of primary trisomics except the pseudonormal one can be distinguished from each other by major morphological characters. The transmission rate of extra chromosome ( through female gamete ) is about 33%.Their usefulness in genetical researches is: ( 1 ) examining the reliableness of results of linkage analysis by traditional methods; (2) testing the independence of linkage groups and ( 3 ) locating the new mutation genes.

初级三体是一种十分重要的作物遗传测验种。作者对水稻三体的有关下列问题作了评述:(1)来源;(2)形态分类;(3)细胞遗传学和(4)在遗传研究上的应用。 1975年国际水稻研究所利用形态学和细胞学建立了一套灿稻初级三体。十二类型的三体中除伪正常型外均能从外部形态加以区别,其额外染色体的传递率(通过雌配子)约为33%. 水稻初级三体在遗传研究上的用途为:(1)检验用传统方法所得连锁遗传分析结果的可靠性;(2)测定连锁群的独立性;(3)对新的突变基因进行定位。

 
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