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bioassay     
相关语句
  生物测定
     Bioassay tests showed that compound 3f could inhibit PC3 cell proliferation at the concentration of 20 μg/mL with the inhibition rate 84.3%.
     生物测定表明化合物3f在20μg/mL浓度下对PC3细胞的抑制率为84.3%.
短句来源
     The results of bioassay indicated that the LC 50 of 2nd and 3rd instar of Spodoptera exigua was 6.6 ×10 4 and 2.6×10 5 PIB/ml.
     生物测定的结果表明其对二龄、三龄甜菜夜蛾的LC50 分别为 6 .6× 10 4,2 .6× 10 5PIB/mL .
短句来源
     Toxicity bioassay showed 4Q7(pHcy1) and 4Q7(pHcy3) exhibited a comparable mosquito-larvicidal activity against 3~(rd)-instar Culex quinquefasciatus.
     另外,生物测定结果表明重组菌株4Q7(pHcy1)和4Q7(pHcy3)对三龄致倦库蚊的杀虫活性没有显著性差异。
短句来源
     BIOASSAY OF ANTIBIOTIC 2233wp
     抗生素2233wp的生物测定方法
短句来源
     Bioassay for Herbicidal Activity of New Compound JS412
     新化合物JS412除草活性的生物测定
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  生物测试
     Method WHO standard bioassay was employed to calculate LC(50 ), regression equation and synergistic coefficients.
     方法采用WHO生物测试法,计算LC50、回归方程、增效系数。
短句来源
     Methods: WHO standard bioassay was employed to calculate LC50, regression equation and synergistic coefficient.
     方法:采用WHO生物测试法,计算LC50、回归方程、增效系数。
短句来源
     Methods WHO standard bioassay was employed to calculate LC_ 50 , regression equation and resistance index.
     方法采用WHO标准生物测试法,计算LC50、回归方程及抗性倍数。
短句来源
     Methods WHO standard bioassay was employed to calculate LC_~50 and synergistic coefficient.
     方法采用WHO生物测试法,计算LC50、增效系数。
短句来源
     Method WHO standard bioassay was employed to calculate LC50,regression equation and synergistic coefficients.
     方法采用WHO生物测试法,计算LC50、回归方程、增效系数。
短句来源
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  生物鉴定
     Using the bioassay of porcine coronary artery strips, F 3(10 -6 , 10 -5 and 10 -4 moL/L)were added into the bath medium prior to KCl(10~40mmoL/L)administration to observe the effect of F 3 on dose-response curve of contraction induced by KCl, and the block action of F 3(10 -4 moL/L)on the contraction induced by KCl respectively;
     利用猪冠状动脉条生物鉴定 ,观察F3( 10 - 6 ,10 - 5 and 10 - 4moL/L)对KCl( 10~ 4 0mmoL/L)诱导的冠脉条收缩的拮抗作用 ,阻断由KCl( 40mmoL/L)诱导的冠脉条的收缩 ;
短句来源
     Synthesis and Bioassay of a Fluorine-Containing Cytokinin,N~6-Pentafluorobenzyladenosine
     含氟细胞分裂素,N~6-五氟苄基腺苷的合成和生物鉴定
短句来源
     The Bioassay, Extraction and Toxicity of T-2 Toxin
     T-2毒素的生物鉴定、提取及对动物的毒性
短句来源
     The results as following:In aspect of the bioassay of Picea schrenkiana autotoxicity , the results showed that the aqueous extracts from the needles of Picea schrenkiana has autotoxicity on seed germination and seedling growth of Picea schrenkiana under two different temperature conditions (①photoperiod 20℃, 16h, dark cycle 15℃, 8h;②The photoperiod 15℃, 16h, the dark cycle 10℃, 8h).
     研究所得结果如下:在自毒作用的生物鉴定方面,两种温度条件(①光周期20℃、16h,暗周期15℃、8h;②光周期15℃、16h,暗周期10℃、8h)的实验表明,天山云杉针叶水浸提取液对其种子萌发和幼苗生长存在自毒作用。
短句来源
     Improvement of a Method of IAA Bioassay
     生长素(IAA)生物鉴定方法的改良
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  生物检定
     Methods: Using the bioassay of rat aorta spiral strips, F 2( 2×10 -6 ?6 32×10 -6 ?2×10 -5 mol/L)was added into the bath medium prior to KCl(10~40mmol/L)admi nistration to observe the effect of F 2 on dose respons e curve of constriction in duced by KCl, respectively.
     方法 :采用生物检定法 ,以大鼠胸主动脉螺旋条为标本 ,观察F2 (2× 10 - 6 、 6 32× 10 - 6 、 2× 10 - 5mol L)对KCl(10~4 0mmol L)诱导的肌条收缩的拮抗作用 ;
短句来源
     METHODS :By using bioassay of porcine coronary strips,Hal(10-4 mol/L/and 2×l0-4 mol/L)was added into the bath medium prior to KCl(10~50 mmol/L)administration separately to observe the effect of Hal on dose-response curve of contraction induced by KCl.
     方法:利用猪冠脉条生物检定,分别加入10-4mol/L和2×10-4mol/LHal于孵育液内,观察对KCl(10~50mmol/L)致猪冠脉条收缩量效曲线的影响。
短句来源
     A BC1 population derived from a artificially selected elite clone "Populusdeltoides Bartr. CL. 'Nankang1'" with borer properties back-cross with its maleparent as materials, by using the methods of bioassay and quantitative trait locus(QTLs), the chemical plant defense mechanism was studied in the erperiment.
     本文以经人工选育出对天牛具有抗性的优良美洲黑杨无性系一南抗杨1号(Populuf. deltoides Bartr.CL.‘Nankangl’)与其父本回交产生的回交一代(BC1)为实验材料,通过生物检定(Bioassay)和数量性状基因定位(Quantitative Trait Locus,QTLs)的方法,研究了植物的化学防御机理。
短句来源
     Methods: The level of slow reaction substance (SRS) and leukotriene B4 ( LTB4) in polymor-phonuclear leukocytes ( PMNs ) in rats in vitro were determined with bioassay and HPLC.
     方法:采用生物检定法和HPLC法测定大鼠多形核粒细胞(PMNs)中慢反应物质(SRS)和白三烯B_4(LTB_4)的含量。
短句来源
     Thrombopoietin(Tpo) concentration-dependent proliferation of TD-3 celis of Mpl receptor gene transfected celi line was observed by means of MTT method for the purpose of establishing a new bioassay method to determine the biological activity of Tpo in samples or products in vitro.
     为建立体外检测血小板生成素(thrombopoietin,Tpo)生物活性的生物检定方法,采用MTT法观察了转染Mpl受体基因的TD-3细胞株依赖于Tpo浓度的增殖特性。
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  bioassay
Bioassay showed that some of the title compounds had high plant-growth regulatory activity.
      
The antifeedant rate in choice test reached 62%-86% at the dose 2.5 mg/mL, while in non-choice bioassay the rate was only 20%-29%.
      
In choice bioassay, the antifeedant rate increased with larval instars of C.
      
The obtained myoblast cultures were used in the clinical tests of cell-mediated gene therapy of Duchenne's muscular dystrophy as well as in the bioassay for the effects of biologically active compounds.
      
On bioassay, BBAP1 exhibited antiviral activity against sunnhemp rosette virus infecting Cyamopsis tetragonoloba leaves in which 95% inhibition of local lesion formation was observed.
      
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Uterine spontaneous contraction and the irregular responses of uteri towards same doses of pituitary extract were very often encountered in the uterus method for pituitary bioassay.The rate of successful experiments was variable.It was found that uteri obtained from rats in proestrus stage gave much better results than those in either diestrus or estrus.Experiments employing ovarietomised rats treated or untreated with hexoestrol dipropionate also showed that uteri from rats in artificial diestrus gave...

Uterine spontaneous contraction and the irregular responses of uteri towards same doses of pituitary extract were very often encountered in the uterus method for pituitary bioassay.The rate of successful experiments was variable.It was found that uteri obtained from rats in proestrus stage gave much better results than those in either diestrus or estrus.Experiments employing ovarietomised rats treated or untreated with hexoestrol dipropionate also showed that uteri from rats in artificial diestrus gave disappointing results but uteri in artificial proestrus were as good as those in normal proestrus(Table Ⅰ). Table Ⅰ.Rate of Successful Experiments of Pituitary Assay Using Rat Uterus Method on Uteri in Different Stages of Estrous Cycle Rats(120—230g) Groups No.of Animals Used Rate of Successful Experiments Normal Diestrus 10 2/10 Proestrus 10 10/10 Estrus 10 6/10 Ovariectomised Treated with Hexoestrol dipropionate(artificial proestrus) 5 5/5 Untreated(artificial diestrus) 5 0/5 Reports on using diestrus uteri in rat uterus method for pituitary assay in previous literature are therefore proved to be not well founded. The possibility and problems involved in employing artificial proestrus uteri in pituitary assay are discussed.

1.利用大白鼠子宫法来测定脑垂体后叶时,以采用在前情期的动物可以得到最高的成功率.研究中所用的十个动物得到完全成功的结果,在经常检定工作中亦证实了此点.因此对大白鼠法提供了通过阴道涂片选择动物的改进方法.2.实验结果否定了关于过去文献介绍应用间情期动物的记载.3.讨论了雌性激素处理过的大白鼠(人工前情期)应用于脑垂体后叶检定的可能性,和可能影响检定结果的因素.

Since 1954 in authors' laboratory, various digitalis preparations, including digitalis leaves, tablets and tinctures and digitoxin and its injections, were assayed by both guineapig method and pigeon (lethal dose) method, using standardized digitalis powder as reference standard. It was found that results of digitalis leaf preparations obtained by guinea pig method and those by pigeon method were reasonably agreeable; while the results of digitoxin preparations obtained by guinea pig method were always significantly...

Since 1954 in authors' laboratory, various digitalis preparations, including digitalis leaves, tablets and tinctures and digitoxin and its injections, were assayed by both guineapig method and pigeon (lethal dose) method, using standardized digitalis powder as reference standard. It was found that results of digitalis leaf preparations obtained by guinea pig method and those by pigeon method were reasonably agreeable; while the results of digitoxin preparations obtained by guinea pig method were always significantly lower than those obtained by pigeon method. In this paper, these facts were again shown, when 6 digitalis leaf preparations and 7 commercial digitoxin preparations were investigated. In digitoxin preparations, the potency estimated by pigeon method could be 2.36 times greater than that estimated by guinea pig method. The authors ascribed the difference to the inadequate standard preparation employed in the assay, as digitalis purpurea consisting of chiefly purpurea glycosides A and B being different in the mode of action to digitoxin (commercial) which was chiefly degraded product of purpurea glycoside A. They concluded that in bioassay of digitoxin against a digitalis standard, a suitable authorised method should be strictly followed; and the 4 methods employing different kinds of animals recommended by British Pharmacopeia 1953 and quoted by Bristish Pharmacopeia Codex 1954 for digitoxin would make confusions.

1、本文用豚鼠法和鸽法比較了6种国产洋地黄粉、2种国产洋地黄毒甙和5种进口洋地黄毒甙的生物效价,用洋地黄粉作标准品。 2、洋地黄粉用两种方法測定的結果比較接近。洋地黄毒甙相差达一倍,鸽法的結果较高,此种較大的差异,显然是与样品和标准品在成分上的不同有关。 3、本文指出英国副藥典(1954)对洋地黃毒甙的检驗,叫种方法并列,并以洋地黄叶粉为标准品是有問題的。作者考虑到如果用一定純度的洋地黄毒甙作为生物检定的标准品时,各法可以并用,否則应按一种規定的方法进行。本室張淑坤、赵秀文、周海鈞三位同志曾参与本文一部分实驗工作。

Divasid, a cardiac glucosidal preparation obtained from the fruits of Yang-chiao-ou [Stropanthus divaricatus (Lour) Hook et Arn.], has been used as a substitute for kstrophanthin in the treatment of heart failure. The authors' study was to determine whether the methods for estimating the potency of digitalis preparations described in the Pharmacopeia of People's Republic of China could be applied to the assay of divasid. It was observed that in several, batches of samples the ratio of the M.L.D. of divasid...

Divasid, a cardiac glucosidal preparation obtained from the fruits of Yang-chiao-ou [Stropanthus divaricatus (Lour) Hook et Arn.], has been used as a substitute for kstrophanthin in the treatment of heart failure. The authors' study was to determine whether the methods for estimating the potency of digitalis preparations described in the Pharmacopeia of People's Republic of China could be applied to the assay of divasid. It was observed that in several, batches of samples the ratio of the M.L.D. of divasid in pigeons to that in cats was almost constant, which was analogous to the ratio obtained with g-strophanthin. Experiments in pigeons gave a coefficient of variation of 9.75% and those in cats 14.56%. Hence, a non-anesthetized pigeon method for bioassay of divasid with strophanthin G as standard was proposed. According to the method proposed the potencies of 18 batches of divasid (both the powder and the injection) were estimated. The fiducial limits of error (P=0.95) of the estimated potencies were around 10%.

1.证明了以鸽法测定g-毒毛旋花子甙最小致死量的实验误差远较猫法为小,而精密度较高。 2.g-毒毛旋花子甙或羊角拗甙对鴿与猫的公斤致死量之比值为2,几乎是恆定的。 3.以g-毒毛旋花子甙为标准品,应用不麻醉鴿法,进行羊角拗甙的效价测定,是一种简易可靠的方法。 4.不同的麻醉剂与稀释剂,并不影响猫的最小致死量。

 
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