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diabetic     
相关语句
  糖尿病
     CLINICAL AND EXPERIMENTAL STUDIES ON THE TREATMENT OF DIABETIC CARDIOPATHY WITH KAIXIN CAPSULE
     开心胶囊治疗糖尿病性心脏病的临床与实验研究
短句来源
     Research on Molecular Genetics and Early Prevention of Diabetic Nephropathy
     糖尿病肾病分子遗传学和早期防治研究
短句来源
     THE RESEARCHES ON TREATMENT OF DIABETIC NEPHROPATHY BY TANGSHENKANG AND INFLUENCE ON IL-13 AND ET-1
     糖肾康治疗糖尿病肾病及对白细胞介素-13和内皮素-1影响的研究
短句来源
     The Study of Renoprotective Effects of Angiotensin Ⅱ Receptor Antagonist on Diabetic Rat and Its Mechanism
     血管紧张素Ⅱ受体拮抗剂对糖尿病大鼠肾脏的保护作用及其作用机制的研究
短句来源
     Relation between Syndrome Differentiation Type of 2 Type Diabetic Microangiopathy and ACE Gene Polymorphism
     糖尿病辨证分型与ACE基因多态性相关研究
短句来源
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  糖尿病患者
     Clinieal Characteristics of Acute Cerebrovascular Diseases in Diabetic Elderly Patients
     老年糖尿病患者的急性脑血管病的临床特点
短句来源
     VITRECTOMY FOR VITREOUS HEMORRHAGE IN CHINESE DIABETIC PATIENTS
     玻璃体切割术治疗中国糖尿病患者的玻璃体出血
短句来源
     NEGATIVE BALANCE OF MAGNESIUM AND HYPOMAGNESEMIA IN DIABETIC PATIENTS
     糖尿病患者镁负平衡与低镁血症
短句来源
     ERYTHROCYTE SODIUM CONTENT AND SODIUM TRANSPORT IN DIABETIC PATIENTS
     糖尿病患者红细胞钠含量和钠转运
短句来源
     Influence of Different Sensitivities on the.Duration and Amplitude of Electromyogram in 60 Diabetic Patients
     不同灵敏度对糖尿病患者60例肌电图时限和波幅的影响
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  糖尿病性
     CLINICAL AND EXPERIMENTAL STUDIES ON THE TREATMENT OF DIABETIC CARDIOPATHY WITH KAIXIN CAPSULE
     开心胶囊治疗糖尿病性心脏病的临床与实验研究
短句来源
     CGT and CalpainⅡ Expressions in Experimental Diabetic Polyneuropathy and the Effects of Human Nerve Growth Factor
     实验性糖尿病性多发性神经病CGT、calpainⅡ的表达及人神经生长因子的干预作用
短句来源
     The Pharmacodynamics Experiment and Mechanism Study on Treatment of Diabetic Coronary Heart Disease by Tangguankang Capsule
     芪玄益心胶囊治疗糖尿病性冠心病的药效学实验及机制研究
短句来源
     The Role of Angiotensin Ⅱ and Nerve Growth Factor in the Pathogenesity of Diabetic Erectile Dysfunction
     血管紧张素Ⅱ和神经生长因子与糖尿病性勃起功能障碍的相关性研究
短句来源
     Diabetic Osteoporosis and Changes of Calcium and Phosphorus: Observation in 100 Diabetics
     糖尿病性骨质疏松与钙磷变化(附100例糖尿病人的观察与讨论)
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  型糖尿病
     Experimental Study of Tang Mai Ping in Treating Type 2 Diabetic Rats
     糖脉平对2型糖尿病及血管病变大鼠治疗作用的实验研究
短句来源
     Study on the Relationship between Chymase Gene Polymorphism and Type 2 Diabetic Complications
     糜酶基因多态性与2型糖尿病并发症关系的研究
短句来源
     The Factors Influencing Plasma Homocysteine in Type 2 Diabetes and the Relationship between Homocysteine and Diabetic Vascular Disease
     2型糖尿病中影响血浆同型半胱氨酸水平的因素及其与血管并发症的关系
短句来源
     Analysis of Clinico-pathological Features and Prognosis in Patients with Type 2 Diabetic Nephropathy
     2型糖尿病肾病临床病理特征及预后分析
短句来源
     Mutation-function Analysis in the Lipoprotein Lipase Gene in Hypertriglyceridemic Members of Type 2 Diabetic Pedigrees
     2型糖尿病家系中高甘油三酯血症患者脂蛋白酯酶基因突变及功能分析
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  diabetic
The increased glucose flux through this metabolic pathway has been linked to the development of diabetic complications such as neuropathy, nephropathy, retinopathy, and cataract.
      
Inhibitors of AR thus seem to have the potential to prevent or treat diabetic complications.
      
Diabetic complications including nephropathy, neuropathy, and cataract are leading causes of end-stage renal diseases and neurological disorders.
      
Excessive accumulation of intracellular sorbitol found in various tissues of diabetic animals and in cells cultured under high glucose conditions has been proposed to be an important factor for the pathogenesis of diabetic complications.
      
Indole ring-containing AR inhibitors have received considerable attention as potential treatments for diabetic complications.
      
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Problems concerning the toxicity of tetracycline, 4-epitetracycline, anhydrotetracycline and anhydro-4-epi-tetracycline are discussed in this paper. Among the above preparations, the 4-epi-tetracycline is most toxic to mice. When given intravenously its LD_(50) to mice is 85.8 mg/kg, as compared with 160.7 mg/kg of tetracycline, 134.2 mg/kg of anhydrotetracycline and 193 mg/kg of anhydro-4-epi-tetracycline. In sub-acute toxicity study anhydro-4-epi-tetracycline exhibited most toxic effects in mice. When given...

Problems concerning the toxicity of tetracycline, 4-epitetracycline, anhydrotetracycline and anhydro-4-epi-tetracycline are discussed in this paper. Among the above preparations, the 4-epi-tetracycline is most toxic to mice. When given intravenously its LD_(50) to mice is 85.8 mg/kg, as compared with 160.7 mg/kg of tetracycline, 134.2 mg/kg of anhydrotetracycline and 193 mg/kg of anhydro-4-epi-tetracycline. In sub-acute toxicity study anhydro-4-epi-tetracycline exhibited most toxic effects in mice. When given intravenously 1 mg/day, or even 12 mg/day orally, severe diabetic urine and proteinuria were observed, and serious pathologic change of the convoluted tube appeared. Our experiment indicates that anhydro-4-epi-tetracycline may be the chief material responsible for Fanconi syndrome.

本文比较了四环素,脱水四环素,叉向四环素及脫水叉向四环素的毒性。急性毒性以叉向四环素为最大,小白鼠靜脉LD_(50)为85.8毫克/公斤,而四环素,脫水四环素及脫水叉向四环素的LD_(50)分別为160.7毫克/公斤,134.2毫克/公斤及193毫克/公斤。亚急性毒性则以脫水叉向四环素为最大,小白鼠不论靜脉注射1毫克/0.5毫升或口服12毫克/0.2毫升,均能出现较重的糖尿及蛋白尿,肾曲管发生较重的病变,可能是临床引起Fanconi症候羣的主要物质。

14 cases of hyperosmolar nonketotic diabetic coma were reported. These accounted for 15.5% of diabetic coma patients seen during the past 20 years. There were 9 female and 5 male patients. 8 were over 60 years old. Half or them gave no history of diabetes. The most important precipitating factor was infection (8 cases). Other factors included infusion of large dose of glucose or hydrocortisone, intake of large amount of sweet beverage, withdrawal of insulin, psychic stress and gastrointestinal disorders....

14 cases of hyperosmolar nonketotic diabetic coma were reported. These accounted for 15.5% of diabetic coma patients seen during the past 20 years. There were 9 female and 5 male patients. 8 were over 60 years old. Half or them gave no history of diabetes. The most important precipitating factor was infection (8 cases). Other factors included infusion of large dose of glucose or hydrocortisone, intake of large amount of sweet beverage, withdrawal of insulin, psychic stress and gastrointestinal disorders. The clinical pictures consisted mainly of neurological syndrome and profound dehydration. About half of the patients were in frank coma, the others were unconscious or mentally confused. 2 had paralysis, 1 had seizures and 3 had circulatory collapse. Laboratory findings were: mean plasma glucose 656.7 mg/dl, mean serum sodium 147.7 mEq/l and mean serum osmolarity 356.3 mOsm/kg. The mortality rate was 64.3% in this series. The main causes of death were infections, shock, electrolyte disturbances and cerebral edema. With adequate hydration, use of hypotonic saline, correction of electrolyte disturbances, small dose of insulin and vigorous treatment of infections, our last 4 patients survived.

本文报道14例高渗性非酮症性糖尿病昏迷。本病多见于老年,其主要诱因为感染,其他为胃肠道功能紊乱,停用胰岛素,进食过多甜食,精神刺激和用药不当。主要临床特征为神经系症状昏迷,严重脱水,重度高血糖,血浆渗透压增高。本综台征易于误诊,本组死亡率高达64.3%。治疗上补液要足量,一部分补液须用0.45%低渗盐水,胰岛素剂量宜较小,补钾要充分,需密切观察,随时调整,以期提高治愈率,降低死亡率。

The beat to beat variation of heart rate, Valsalva test and the difference in blood pressure taken in supine and upright position were studied in 3 groups of individuals, namely, group A——100 normal persons as control; group B——45 cases of diabetes without autonomic neuropathy, and group C——70 cases of diabetes with autonomic neuropathy. In group A, B and C, (1) the difference in heart rate between deep inspiration and expiration was 19.5±1.3, 18.7±1.3 and 11.1±1.2 beats per minute; (2) the response index to...

The beat to beat variation of heart rate, Valsalva test and the difference in blood pressure taken in supine and upright position were studied in 3 groups of individuals, namely, group A——100 normal persons as control; group B——45 cases of diabetes without autonomic neuropathy, and group C——70 cases of diabetes with autonomic neuropathy. In group A, B and C, (1) the difference in heart rate between deep inspiration and expiration was 19.5±1.3, 18.7±1.3 and 11.1±1.2 beats per minute; (2) the response index to Valsalva maneuver was 1.215±0.020, 1.237±0.037 and 1.109±0.022; (3) the difference of heart rate in upright and supine position was 17.9±1.7, 21.6±2.4 and 13.1±1.7 beats per minute; (4) the ratio of 30th to 15th R-R intervals was 1.105±0.15, 1.063±0.021 and 1.001±0.011 and (5) the average difference in blood pressure taken in supine and upright position was 2.76, 7.87 and 11.57 mmHg respectively. 11 eases (15.7%) in group C showed orthostatic hypotension. There were significant difference (p<0.001) between group A or B and group C in beat to beat variation of heart rate. All the above methods are non-invasive and easily accepted by patients, while these methods may be quite helpful in early diagnosis of diabetic cardiovascular autonomic neuropathy.

本文报道对100名正常人(对照组),45例无植物神经病变的糖尿病者(糖尿组)及70例伴植物神经病变的糖尿病者(糖植组)分别作心搏间距变化及卧立位血压差等无创性测定的结果。对照组或糖尿组的吸呼差、乏氏动作反应指数、立卧差、30/15比值与糖植组相比均有显著差异(P<0.001),且糖植组中有11例为姿位性低血压,故提示心搏间距变化及卧立位血压等测定有助于糖尿病性心血管植物神经病变的早期诊断。

 
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