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ectopic
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  异位
     Experimental Study on Ectopic Endometrium of Endometriosis
     子宫内膜异位异位内膜的实验研究
短句来源
     Ectopic Pinealoma
     异位松果体瘤
短句来源
     ECTOPIC URETERAL ORIFICE IN FEMALE:A REPORT OF 18 CASES
     女性输尿管异位开口的手术治疗(附18例报告)
短句来源
     Ectopic Ureteral Orifice in Children: An Analysis of 21 Cases
     小儿输尿管异位开口21例临床分析
短句来源
     Diagnosis and Treatment of Children with Ectopic Ureteral Orifice
     小儿输尿管异位开口的诊断与治疗
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  异位的
     the coincidence rate of B-ultrasound located ectopic IUD is 54.55 percent;
     B超定位IUD异位的符合率为54.55%;
短句来源
     Diagnosis and treatment of ectopic ureter in children (report of 22 cases)
     小儿输尿管开口异位的诊断和治疗(附22例报告)
短句来源
     From 1972 through 1995,9 cases of ectopic bowel were found among 80 cases of bladder extrophy,including 6 boys and 3 girls with an average of 2.9 years old.
     为了提高对膀胱外翻合并肠异位的认识及提高诊治效果,报告自1972~1995年收治各型膀胱外翻80例中合并肠异位者9例,占11%。 其中男6例,女3例,平均年龄2.9岁。
短句来源
     Diagnosis and Treatment of Congenital Ectopic Kidney With Ectopic Opening of Ureter (Report of 7 cases)
     先天性异位肾伴输尿管开口异位的诊断和治疗(附7例报告)
短句来源
     Objective : To evaluate the methods for diagnosis and treatment of ectopic intrauterine contraceptive devices(IUD) .
     目的:探讨宫内节育器(Intrauterine Contraceptive Device,IUD)异位的诊断及其防治措施。
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  “ectopic”译为未确定词的双语例句
     Inhibition of Cell Proliferation and Induction of p21~(WAF1) by Ectopic Expression of Cyclin G2
     Cyclin G2抑制细胞增殖的实验研究
短句来源
     Anti-tumor Effects of a Novel Gene Vaccine Against Ectopic Human Chorionic Gonadotrophin (ehCG)
     基于ehCG新型肿瘤基因疫苗的分子设计及其抗瘤效应
短句来源
     Efects of Eleng Capsule on the Expression of MMPs, TIMPs and VEGF in Ectopic and Eutopic Endometrium from Endometriosis
     莪棱胶囊治疗子宫内膜异位症对MMPs/TIMPs和VEGF表达的影响
短句来源
     An Experimental Study of Establishment of Brain Tumor Animal Model and Gene Therapy for Glioma with Ectopic P21~(WAFI/CIP1) Gene
     脑胶质瘤动物模型的建立及外源性P21~(WAFI/CIP1)基因治疗胶质瘤的实验研究
短句来源
     1.Expressions and Partial Purifications of hBMP2 and hBMP3 in Insect Cells and Their Ectopic Bone-inducingActivities in Mice and Some Effects on Mc3T3 Cells
     1.人骨形成蛋白2和3在昆虫杆状病毒表达系统中的表达纯化及活性研究 2.人骨形成蛋白2和3鼠单克隆抗体的制备及初步鉴定
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  ectopic
The capacity of stromal cells to form ectopic hematopoietic foci was considerably decreased and also remained low for 10 months.
      
Our main message in this report is that repositioning of a new duplicate to an ectopic site epigenetically alters its expression pattern, and concomitantly the rate and direction of mutations.
      
A similar set of homologous regulatory and nuclear genes controls morphogenesis during formation of the ectopic eyes in Drosophila and vertebrates.
      
Chondrogenesis and Osteogenesis in Ectopic Transplants of the Fetal Liver in Mice
      
The method of ectopic transplantation of embryonic CNS rudiments makes it possible to study the mechanisms underlying adaptation of the transplanted embryonic rudiments.
      
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Vagal excitation has been alleged to be responsible for the setious ventricular irregularities during antimortial therapy of schistosomiasis.However,the facts that potassium antimony tartrate(PAT)potentiates the fibr.1latory action of adrenaIine experimentally and that the cholinolytic,atropine,has not been entirely successful in treating antimonial arrhythmia clinicany,suggested the desirability of reinvestigating the mechanism of this arrhythmia. Rabbits of either sex were anesthetized bv intravenous sodium...

Vagal excitation has been alleged to be responsible for the setious ventricular irregularities during antimortial therapy of schistosomiasis.However,the facts that potassium antimony tartrate(PAT)potentiates the fibr.1latory action of adrenaIine experimentally and that the cholinolytic,atropine,has not been entirely successful in treating antimonial arrhythmia clinicany,suggested the desirability of reinvestigating the mechanism of this arrhythmia. Rabbits of either sex were anesthetized bv intravenous sodium pentobarbitaI Two electrodes were attached to the base and the apex of the exposed heart,and the threshold voItage for inducing ventricular fibrillation(EVFT)was determined. PAT in Successive doses of 3,6,12mg/kg was found to lowet the EVFT,accelerate the heart,alld depress gradually the arterial blood pressure;a subsequent larger dose of PAT(24 Or 36 mg/kg)tlsuaUy induced ventricular fibrillation(VF)by itself.This EVFT-lowering effect of PAT was totally reversed by bilateral vagotomy,bilateral sympathectomy or reserpinization,but was scarcely affected by atropine at the dosage level of 0.2 or 2mg/kg.The cardiac acceleration was reversed into bradycardia by sympathectomy,resetpinization or 2mg/kg of atropime but remained unchanged after vagotomy or O.2 mg/kg of atropiDe.Against the PAT-induced VF,however,Deither vagotomy nor the smalI dose of atropine gave any protection,whiIe sympathectomy,resetpinization or the large dose of atropine totally abolished this effect.Moreover,atroplne in 0.2mg/kg doses,definitely vagolytic in pentobarbitaIized rabbits,did not prevent the ventricular irregularities(or ectopic rhvthm)of noradrenaline in unanesthetized rabbits,although the larger dose(2mg/kg)did prevent them. From the above findings,it may be deduced that,under these experimental condltions,the EVFT—loweting effect of PAT is closely related to the intactness of the cardlac sympathetjc or the cardiac store of its transmitter.The natulTe of the vagal role in thls connection remains to be determined,probably the vagus acts as the afferent path in the reflex arc,in which the sympathetic acts as the efferent.The PAT-induced cardiac acceleration and VF apparently bear no relationship to the vagus;their developmerit is chiefly,if not soleIy,depelldent on the cardiac symoathetic or its catecholamine store.

在戊巴比妥钠麻醉兔观察酒石酸锑钾(锑钾)对电致颤阈的影响,锑钾本身所致的心室颤动,以及心脏神经对锑钾作用的影响。结果发现:一定剂量的锑鉮(依次地静脉注射3,6,12毫克/公斤)能显著地降低电致颤阈(9/10兔),并使心率稍有加速(8/10兔),血压缓慢而逐步下降;大剂量(24—36毫克/公斤)使血压迅速而显著下降,6/10兔出现锑致性心室颤动。在切断迷走神经,切除交感神经或利血平化以后,锑钾的降低电致颤阈的作用不仅被防止并且全部翻轉,阿托品(0.2或2毫克/公斤)均不能显著地影响这种致颤阈的降低。锑钾所致的心率加速作用为切除交感神经,利血平化或大剂量阿托品所防止而且翻轉,相反,在切断迷走神经与小剂量阿托品后,心率加速仍然出现。切断迷走神经与小剂量阿托品完全不能防止锑致性心室颤动,分别仍有4/5与5/6兔出现颤动,而切除交感神经,利血平化或大剂量阿托品则能完全防止之。此外,于不麻醉兔小剂量阿托品不影响,而大剂量阿托品能防止去甲腎上腺素的心律紊乱。根据实验结果,可以作出推论如下:在本实验条件下锑钾的降低电致颤阈的作用是与心脏交感神经的完整性或心内儿茶酚胺储存量有关;至于迷走神经的意义尚待阐明,可能为组成此反射弧的...

在戊巴比妥钠麻醉兔观察酒石酸锑钾(锑钾)对电致颤阈的影响,锑钾本身所致的心室颤动,以及心脏神经对锑钾作用的影响。结果发现:一定剂量的锑鉮(依次地静脉注射3,6,12毫克/公斤)能显著地降低电致颤阈(9/10兔),并使心率稍有加速(8/10兔),血压缓慢而逐步下降;大剂量(24—36毫克/公斤)使血压迅速而显著下降,6/10兔出现锑致性心室颤动。在切断迷走神经,切除交感神经或利血平化以后,锑钾的降低电致颤阈的作用不仅被防止并且全部翻轉,阿托品(0.2或2毫克/公斤)均不能显著地影响这种致颤阈的降低。锑钾所致的心率加速作用为切除交感神经,利血平化或大剂量阿托品所防止而且翻轉,相反,在切断迷走神经与小剂量阿托品后,心率加速仍然出现。切断迷走神经与小剂量阿托品完全不能防止锑致性心室颤动,分别仍有4/5与5/6兔出现颤动,而切除交感神经,利血平化或大剂量阿托品则能完全防止之。此外,于不麻醉兔小剂量阿托品不影响,而大剂量阿托品能防止去甲腎上腺素的心律紊乱。根据实验结果,可以作出推论如下:在本实验条件下锑钾的降低电致颤阈的作用是与心脏交感神经的完整性或心内儿茶酚胺储存量有关;至于迷走神经的意义尚待阐明,可能为组成此反射弧的传入通路,而以交感神经为其传出通路。锑钾加速心率的作用及大剂量所致的锑致性心室颤动则与迷走神经无关,而是取决于交感神经的完整性或心肌内的儿茶酚胺储存量。大剂量阿托品对锑致性心室颤动与去甲腎上腺素的心律紊乱均有保护作用,这可能是通过对抗迷走神经以外的机制。

Radix trichosanthes is an abortifacient drug of mid-gestation and is extracted from the root tuber of Trichosanthes kirilowii Maxim (Cucurbitaceae).The purified effective principle is a basic protein of molecular weight of appoximately 18,000 and is named "Trichosan'thin".It is proved to be very effective in abortion induction of mid-gestation,particularly effective in treating ectopic pregnancy,hydatidiform mole and invasive mole,and it has also some therapeutic action on choriocarcinoma.Based upon the...

Radix trichosanthes is an abortifacient drug of mid-gestation and is extracted from the root tuber of Trichosanthes kirilowii Maxim (Cucurbitaceae).The purified effective principle is a basic protein of molecular weight of appoximately 18,000 and is named "Trichosan'thin".It is proved to be very effective in abortion induction of mid-gestation,particularly effective in treating ectopic pregnancy,hydatidiform mole and invasive mole,and it has also some therapeutic action on choriocarcinoma.Based upon the experimental results on its initial site of action,its morphological and functional injury on trophoblast cells of placenta both in vivo and in,vitro and its effect on prostaglandin synthesis,the following conclusions are drawn concerning the mechanism of abortifacient action of triohosanthin:(1)Trichosanthin exerts its action directly on the placental trophoblasts and possesses a certain degree of specificity.(2)It selectively produces necrotic degeneration of the syneytiotrophoblasts of placental villi,resulting in fragments of the disintegrated cells clumped in the blood sinus,and the coagulation of blood causing circulation hinderan'ce and followed by large scale tissue necrosis.The necrosis of placental villi is considered to be the primary response.(3)Beside structural injuries the impairemerit of functional activities were also observed.The concentrations of HCG and steroid hormones fell rapidly below the threshold values of threatened abortion.Serious structural and functional injuries brought about destructive effects upon the normal endocrine relationship between the mother and fetus and upon metabolic exchanges.It was further postulated that through certain unknown mechanism the synthesis of prostaglandin was increased,uterine contraction was initiated and abortion ensued.In summary,trichosanthin,a plant protein discovered from Chinese medical herbs,is a drug for abortion induction and also a drug against trophoblastie neoplasms.The preliminary elucidation of the mechanism of this drug on abortion induction has afforded basis for the clinical application with better efficacy and its possible use for an abortifacient in early pregnancy as well as for the discovery of newer cancer chemotherapeutie agents.

天花粉粗提物是从葫芦科植物栝楼的根提取出的中期引产药物,其纯化的引产有效成分为分子量约18,000的碱性蛋白质,称为“天花粉蛋白”。经鉴定对中期妊娠有很好的引产效果。同时,对宫外孕、葡萄胎、恶性葡萄胎有独特的疗效,对绒毛膜上皮癌也有一定的疗效, 根据对天花粉蛋白的原初作用部位,胎盘和离体培养的人滋养层细胞的形态和功能损伤,以及抑制前列腺素合成对天花粉蛋白引产的影响等方面的研究结果,互相印证,初步阐明了天花粉蛋白引产作用原理:(1)天花粉蛋白直接作用于胎盘的滋养层细胞,并有一定的细胞专一性:(2)天花粉蛋白能选择地使胎盘绒毛合体滋养层细胞变性坏死,解体的细胞碎片留在血窦中,引起凝血,造成循环障碍和进一步的大量组织坏死,胎盘绒毛坏死是原发的,循环障碍是继发的:(3)胎盘绒毛的损伤反映在功能方面,HCG和甾体激素迅速下降到先兆流产的临界水平以下。由于胎盘形态和功能严重损伤的结果,破坏了母体和胎儿之间的内分泌关系和代谢物的交换,并假定可能通过尚未弄清楚的机制,引起前列腺素合成的增加,发动宫缩而导致流产。总之,天花粉蛋白是从中草药发掘出来的一个植物蛋白性的中期引产和抗增生性滋养层细胞疾病的药物。天花粉蛋白引产作用原理的...

天花粉粗提物是从葫芦科植物栝楼的根提取出的中期引产药物,其纯化的引产有效成分为分子量约18,000的碱性蛋白质,称为“天花粉蛋白”。经鉴定对中期妊娠有很好的引产效果。同时,对宫外孕、葡萄胎、恶性葡萄胎有独特的疗效,对绒毛膜上皮癌也有一定的疗效, 根据对天花粉蛋白的原初作用部位,胎盘和离体培养的人滋养层细胞的形态和功能损伤,以及抑制前列腺素合成对天花粉蛋白引产的影响等方面的研究结果,互相印证,初步阐明了天花粉蛋白引产作用原理:(1)天花粉蛋白直接作用于胎盘的滋养层细胞,并有一定的细胞专一性:(2)天花粉蛋白能选择地使胎盘绒毛合体滋养层细胞变性坏死,解体的细胞碎片留在血窦中,引起凝血,造成循环障碍和进一步的大量组织坏死,胎盘绒毛坏死是原发的,循环障碍是继发的:(3)胎盘绒毛的损伤反映在功能方面,HCG和甾体激素迅速下降到先兆流产的临界水平以下。由于胎盘形态和功能严重损伤的结果,破坏了母体和胎儿之间的内分泌关系和代谢物的交换,并假定可能通过尚未弄清楚的机制,引起前列腺素合成的增加,发动宫缩而导致流产。总之,天花粉蛋白是从中草药发掘出来的一个植物蛋白性的中期引产和抗增生性滋养层细胞疾病的药物。天花粉蛋白引产作用原理的初步阐明,在实践上为提高和扩大天花粉蛋白的?

111 cases of Cushing's syndrome were analysed in which 101 cases were pathologically proved and 10 were clinically diagnosed. The choice of treatment according to the different pathological types was discussed. In cases of bilateral hyperplastic type without evidence of pituitary tumor (52 cases), bilateral subtotal adrenalectomy followed by pituitary irradiation was preferred. In cases of hyperplastic type with apparent evidence of pituitary tumor (11 cases including one case of Nelson's syndrome), operation...

111 cases of Cushing's syndrome were analysed in which 101 cases were pathologically proved and 10 were clinically diagnosed. The choice of treatment according to the different pathological types was discussed. In cases of bilateral hyperplastic type without evidence of pituitary tumor (52 cases), bilateral subtotal adrenalectomy followed by pituitary irradiation was preferred. In cases of hyperplastic type with apparent evidence of pituitary tumor (11 cases including one case of Nelson's syndrome), operation on pituitary gland should be performed first irrespective of absence of compression syndrome and 3-6 months later followed by subtotal adrenolectomy if necessary, o,p'-DDD and adrenal blockers were used in some of these patients or just pre-operatively. In cases of adrenal cortical adenoma (29 cases), simple unilateral adrenolectomy would produce satisfactory results. Adenocarcinomas of adrenal cortex (8 cases) should receive radical operation while in late inoperable cases, o,p'-DDD was the drug of choice. In one case of ectopic ACTH syndrome, hypercortisolism remitted after an effective treatment of the primary lesion.

本文结合111例皮质醇增多症的临床分析,根据其不同病理类型,对治疗方案的选择进行了讨论。增生型无明确垂体瘸者主张肾上腺次全切除加垂体放疗;有明显垂体瘤者,不论有无压迫症状均主张先行垂体手术,3~6月后皮质醇增多症症状未缓解者,再行肾上腺次全切除术。肾上腺腺瘤手术疗效满意。腺癌应手术根治,晚期不能手术者可用二氯苯二氯乙烷治疗。异位ACTH综合征根治原发病灶后皮质醇增多症可期缓解。

 
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