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degenerative disc
相关语句
  椎间盘退变
     BMP7 Recombinant Adenovirus Therapy of Degenerative Disc Disease
     重组BMP7腺病毒治疗椎间盘退变的实验研究
短句来源
     Association of vitamin D receptor gene TruⅠ and FokⅠ polymorphisms with lumbar degenerative disc disease in Han nationality
     汉族人维生素D受体基因TruⅠ和FokⅠ多态性与腰椎间盘退变的关系
短句来源
     Sox9 gene therapy for intervertebral degenerative disc of animal model
     腺病毒介导的Sox9基因对椎间盘退变动物模型的疗效
短句来源
     Degenerative Disc Animal Model
     椎间盘退变动物模型研究概况
短句来源
     The development of a degenerative disc animal model in bipedal rats
     双后肢大鼠椎间盘退变动物模型的建立
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  退变椎间盘
     Conclusion:Eukaryotic vector PCI-hTGF-β1 constructed in our laboratory can transfect adult degenerative disc cells cultured in vitro. The gene product of hTGF-β1 can be expressed.
     结论:真核表达载体PCI-hTGF-茁1可以成功转染体外培养的成人退变椎间盘细胞,并可获得hTGF-茁1基因产物的高表达。
短句来源
     Methods A new effective CAD method was used to accurately establish 9 finite element models(FEM)which were assembled respectively with facet-joint angle 65°, 45°, 25°, with normal disc, light degenerative disc and severe degenerative disc.
     方法采用一种新型CAD方法精确构建65°小关节角、45°小关节角、25°小关节角与正常椎间盘、轻度退变椎间盘、重度退变椎间盘相组配的9种腰椎L4-L5活动节段有限元模型。
短句来源
     Objectives: 1) To provide experimental foundation for the clinical practice of gene therapy of disc degeneration diseases with transfecting adult degenerative disc cells cultured in vitro and determining the expressive product of hTGF-?
     1(hTGF-?1)基因真核表达质粒并转染体外培养的成人退变椎间盘细胞,测定hTGF-? 1基因的表达产物,为椎间盘退变基因治疗的临床应用提供实验基础。
短句来源
     A STUDY ON CELL CULTURE OF HUMAN DEGENERATIVE DISC AND APOPTOSIS
     人退变椎间盘细胞培养及细胞凋亡的研究
短句来源
     Methods rCreating mechanical model of L3-5 motion segment of nomai and degenerative disc with three dimensional finite element method and the five kinds of stress conditions simulated five kinds of physiologic positions was analyzed comparatively.
     方法:用三维有限元法建立正常及退变椎间盘的L3-5活动节段的力学模型,并对其在直立、前屈、后伸、侧弯及旋转五种外加载荷下的应力分布进行对比分折。
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  “degenerative disc”译为未确定词的双语例句
     In order to make clear the normal height of lumbosacral space, so as to have earlier diagnosis of possible degenerative disc problems therein, olservations and measurements were made on lateral films of normal lumbar spines of 70 males and 50 females at the ages between 20 and 30. The results are as follows: Average height of L_5-S_1 in males, 0.98 cm, S.D.
     为③明确L_5—S_1椎间隙的正常宽度,以期有助于该部位间盘退变的早期诊断,对20—30岁正常男性70例、女性50例侧位平片进行了L_5—S_1椎间隙高度的观测。
短句来源
     Degenerative disc disease pain and gene therapy
     椎间盘退变性疼痛与基因治疗
短句来源
     The expression of the Fas receptor,bcl-2 in the degenerative disc was detected with the immunohistochemistry ABC.
     采用免疫组织化学ABC法检测椎间盘石蜡切片中Fas、bcl 2蛋白的表达情况。
短句来源
     The quantity of NO and IL-6 secreted by Group 3 was significantly greater than Group 1 and Group 5 (P<0.05). Conclusions:Herniated or degenerative disc tissue was of the capacity to secrete inflammatory mediators such as NO and IL-6, and it was increased significantly after nicotine stimulation.
     单个核细胞 +烟碱组比单独单个核细胞组产生的NO和IL - 6量增高 ,差异有显著性 (P <0 .0 5 ,P <0 .0 5 ) ,灭活椎间盘 +单个核细胞培养组比单独椎间盘组和单独单个核细胞组产生生的NO和IL - 6量增高 ,差异有显著性 (P <0 .0 5 ,P <0 .0 5 )。
短句来源
     PDN replacement for the treatment of degenerative disc disease
     人工髓核置换术治疗退变性腰椎间盘病的近期效果
短句来源
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  degenerative disc
Announcement: International Symposium: Degenerative Disc...Disease
      
More recently, an autoimmune reaction has been demonstrated to occur in cases with degenerative disc protrusion.
      
More recently, an autoimmune reaction has been demonstrated to occur in cases with degenerative disc protrusion.
      
The indications for surgery were: degenerative disc disease, degenerative spondylolisthesis and nonunion following previous posterolateral fusion of lumbar spine segments.
      
No changes were observed in von Mises stress on the vertebral endplates or annulus fibrosus in the degenerative disc model, but von Mises stress on the facet joints was about 2.5 times that seen in the normal disc model.
      
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In order to make clear the normal height of lumbosacral space, so as to have earlier diagnosis of possible degenerative disc problems therein, olservations and measurements were made on lateral films of normal lumbar spines of 70 males and 50 females at the ages between 20 and 30. The results are as follows: Average height of L_5-S_1 in males, 0.98 cm, S.D. 0.11 cm; in females, 0.95 cm, S.D. 0.12 cm. Average of L_5-S_1/L_5 ratio, male, 0.299, S.D. 0.040; female, 0.309, S.D. 0.027. It amounts to 89.0% in...

In order to make clear the normal height of lumbosacral space, so as to have earlier diagnosis of possible degenerative disc problems therein, olservations and measurements were made on lateral films of normal lumbar spines of 70 males and 50 females at the ages between 20 and 30. The results are as follows: Average height of L_5-S_1 in males, 0.98 cm, S.D. 0.11 cm; in females, 0.95 cm, S.D. 0.12 cm. Average of L_5-S_1/L_5 ratio, male, 0.299, S.D. 0.040; female, 0.309, S.D. 0.027. It amounts to 89.0% in males and 96.0% in females, who have the heights of their lumbosacral spaces equal to or larger than these of their L_(1-2). The above parameters Can also be applied to young people of the age group between 16 and 19.

为③明确L_5—S_1椎间隙的正常宽度,以期有助于该部位间盘退变的早期诊断,对20—30岁正常男性70例、女性50例侧位平片进行了L_5—S_1椎间隙高度的观测。实测数据均值和标准差如下:男性0.98cm,标准差0.11cm;女性0.95cm,标准差0.12cm。L_5—S_1/L_5比率均值男性0.299,标准差0.040;女性0.309,标准差0.027。L_5—S_1椎间隙高度等于L_(1-2)或>L_(1-2)椎间隙高度者,男性占89.0%,女性占96.0%。前述参数亦适用于20岁以下、16岁以上年令组。

The CT discographic findings from 146 discs in 73 low-back pain and sciatica patients were compared to the provocative pain during the injection of contrast into the disc. Pain reaction to the discogram at each level was recorded as following no pain, dissimilar pain, similar pain, or exact reproduction of the patient's clinical pain. The more precise analysis demonstrated a significant relationship between pain and deterioration of the discs. There were the similar pain and pain reproduction...

The CT discographic findings from 146 discs in 73 low-back pain and sciatica patients were compared to the provocative pain during the injection of contrast into the disc. Pain reaction to the discogram at each level was recorded as following no pain, dissimilar pain, similar pain, or exact reproduction of the patient's clinical pain. The more precise analysis demonstrated a significant relationship between pain and deterioration of the discs. There were the similar pain and pain reproduction in 68. 9% of disruption. The degenerative discs were usually painful and non degenerative discs were generally not painful. The provocative pain is valuable in the diagnosis of low-back pain and sciatica patients with CT discography.

作者对73例腰腿痛患者进行了CTM间盘造影检查,共146个间盘,其中突出51个,退变95个。根据造影中出现诱发疼痛与否,可分为无痛、非类似疼痛、类似疼痛和疼痛再现4类。椎间盘突出中68. 9%有类似疼痛和疼痛再现。突出不合并或合并轻度退变时容易出现疼痛再现,合并严重退变则疼痛再现明显减少。无退变间盘常常是无痛的,退变间盘常有非类似疼痛。椎间盘造影诱发出的不同性质的疼痛有辅助诊断价值。疼痛的病理机制仍有待探讨。

In order to illustrate the pathologic basis and clinic significance of MRI signs of de-generative disc,11 adult cadaver specimens were studied with MRI and pathology. According to the result of examination,the discs were classified into four types. TypeⅠ:normal disc,the shape and signal intensity on MRI appeared to be normal.Type Ⅱ:degenerative disc the shape might be regular or irregular with inhomogeneous decrease of signal intensity.The disc did not extend beyond the pos-terior margin of endplate....

In order to illustrate the pathologic basis and clinic significance of MRI signs of de-generative disc,11 adult cadaver specimens were studied with MRI and pathology. According to the result of examination,the discs were classified into four types. TypeⅠ:normal disc,the shape and signal intensity on MRI appeared to be normal.Type Ⅱ:degenerative disc the shape might be regular or irregular with inhomogeneous decrease of signal intensity.The disc did not extend beyond the pos-terior margin of endplate. Pathologic examination revealed necrotic cartilage cell in annular fibrosus and cartilage endplate,fragmented nucleus pulposus with hemorrhage inflammation, granulation tis-sue overgrowth,fibrotic and cystic changes etc. Type Ⅲ:bulging disc on the basis of type Ⅱ dege-neration,the disc enlarged concentrically and extended beyond the posterior margin of endplate,but without localized herniation. Pathologic examination indicated that annulus fibrosus was torn off,in-vovling the outer layer but with intact xternal surface. Type Ⅳ:disc herniation,besides the changes of signal intensity of typeⅡ,the nucleus pulposus protruded posteriorly through the rup-tured annulus. The posterior longitudinal ligament was displaced or ruptured.

为阐明退变椎间盘MRI征象的病理学基础及临床意义,作者对11具成人脊柱标本椎间盘进行了MRI与病理检查。根据检查结果,将间盘分为四型:Ⅰ型:正常间盘。MRI上其形态及信号强度未见异常,病理仅见纤维环局部断裂。Ⅱ型:退变间盘。其形态不规则,信号强度不均匀减低,间盘未超过终板后缘。病理发现纤维环及软骨终板内有坏死的软骨细胞、破碎的髓核、出血、炎症、肉芽组织、纤维化及囊变等。Ⅲ型:间盘膨出。在退变的基础上,间盘呈同心性扩大并超出终板后缘,但无髓核局部脱出。病理见纤维环断裂,累及外环,表层尚完整。Ⅳ型:间盘脱出。除有Ⅱ型的改变外,髓核通过破裂的纤维环向后脱出,后纵韧带移位或破裂。

 
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