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the redistribution
相关语句
  再分布
    The results of electrochemical corrosion tests show that the thermodynamic stability, passivation stability and anti-breakdown property is also improved in vitro simulated body environment (37±rCTyrode's simulated body fluid), especially the Ti/TiN(45/45s) coating, and the reason is that the sandwich structure, composed of Ti layer-graded layer-TiN layer, plays an important role in inhibition of the penetration of test solution and causes the redistribution of interphase corrosion current density.
    在体外模拟生理环境中,Ti/TiN纳米多层薄膜有效提高金属基体的热力学稳定性、钝态稳定性与抗击穿能力,其中Ti/TiN(45/45s)纳米多层薄膜表现最佳。 Ti层-过渡层-TiN层“三明治”结构可有效抑制腐蚀溶液渗入,且导致相间腐蚀电流的再分布,降低薄膜的腐蚀速率。
短句来源
    Objective To study the effects of mechanical strain on the proliferation of the human pulmonary epithelial cell and the redistribution of its membrane receptors, integrins α 5 and β 1. Methods A cyclic strain unit in vitro was designed.
    目的 探讨机械拉伸应变对人肺上皮细胞增殖及其膜受体———整联蛋白α5、β1 再分布的调控作用。
短句来源
    The cellular proliferative index was measured by flow cytometry and the redistribution of α 5 and β 1 integrins was analyzed in human pulmonary epithelial cell line H727 by laser confocal microscopy.
    方法 建立体外周期性拉伸装置 ,应用流式细胞术测定细胞的增殖活性 ,激光共聚焦显微镜分析整联蛋白α5、β1 再分布
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  the redistribution
On the other hand, the barrier could be significantly altered by the redistribution of excessive charges in the micrometer long SWCNTs, which have only one layer of carbon atoms.
      
A Study of the Redistribution Conditions of Carbon Black Particles from the Bulk to the Interface in Heterogeneous Polymer Blend
      
The redistribution conditions of carbon black particles to the interface between polymers were studied based on the measurement of the value of superadditive conductivity of several heterogeneous polymer blends filled with powdered carbon black.
      
The redistribution of carbon black from the polymer phase that has low ability to wet the powder proceeds efficiently only to the boundary with polymer having better wetting ability.
      
As the storage time of the system increases, the spectrum of diffusion coefficient values varies, thereby indicating the redistribution of PEG400 molecules in the blend with PVP.
      
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Objective To study the effects of mechanical strain on the proliferation of the human pulmonary epithelial cell and the redistribution of its membrane receptors, integrins α 5 and β 1. Methods A cyclic strain unit in vitro was designed. The cellular proliferative index was measured by flow cytometry and the redistribution of α 5 and β 1 integrins was analyzed in human pulmonary epithelial cell line H727 by laser confocal microscopy. Results The cellular proliferative index reduced significantly...

Objective To study the effects of mechanical strain on the proliferation of the human pulmonary epithelial cell and the redistribution of its membrane receptors, integrins α 5 and β 1. Methods A cyclic strain unit in vitro was designed. The cellular proliferative index was measured by flow cytometry and the redistribution of α 5 and β 1 integrins was analyzed in human pulmonary epithelial cell line H727 by laser confocal microscopy. Results The cellular proliferative index reduced significantly after cells were subjected to 15% elongation at frequencies of 20 cycles/min or 40 cycles/min for 24 h. In human pulmonary epithelial H727 cells, α 5 and β 1 integrins transferred from the apical layer to the basal layer and formed an adhesion plaque after 24 h exposure to 15% elongation at frequency of 40 cycles/min. Conclusion The results suggest that α 5 and β 1 integrins in pulmonary epithelial cells may play an important role in the transduction of mechanical stress.

目的 探讨机械拉伸应变对人肺上皮细胞增殖及其膜受体———整联蛋白α5、β1 再分布的调控作用。方法 建立体外周期性拉伸装置 ,应用流式细胞术测定细胞的增殖活性 ,激光共聚焦显微镜分析整联蛋白α5、β1 再分布。结果 在应变为 15 % ,频率为 2 0次 min、40次 min的拉伸刺激下 ,2 4h后 ,细胞的增殖活性指数明显降低 ,H72 7细胞的DNA合成受到显著抑制。在 40次 min的拉伸频率下 ,整联蛋白α5、β1 的分布发生重组并向基底层转移 ,形成局部粘附连接。结论 整联蛋白α5、β1 可能在肺上皮细胞感应机械应力过程中起了重要的作用

In order to study the effects of mechanical strain on distribution of integrins in normal human pulmonary epithelial cell line H727, a cyclic strain unit in vitro was set up, and the redistribution of α3,α5,β1 integrin in H727 cells subjected to 24 h cyclic strain was analyzed. Human pulmonary epithelial H727 cells seeded on either fibronectin or collagen Ⅳ surfaces were subjected to 15% elongation at a frequency of 40 cycles/min. Confocal microcopy revealed that α3,α5,β1 integrin in H727 cells were concentrated...

In order to study the effects of mechanical strain on distribution of integrins in normal human pulmonary epithelial cell line H727, a cyclic strain unit in vitro was set up, and the redistribution of α3,α5,β1 integrin in H727 cells subjected to 24 h cyclic strain was analyzed. Human pulmonary epithelial H727 cells seeded on either fibronectin or collagen Ⅳ surfaces were subjected to 15% elongation at a frequency of 40 cycles/min. Confocal microcopy revealed that α3,α5,β1 integrin in H727 cells were concentrated and brighter,and cells created a large fusion of focal adhesion or adhesion plaques after 24 h exposure to strain. Under static condition, α3,α5,β1 integrin in H727 cells maintained a diffuse pattern with an occasional speckle concentration in some regions. Furthermore α3,α5,β1 integrin in H727 cells transferred from the apical layer to the basal layer and created adhesion plaques, and affinity between integrins and extracellular matrices(ECM) was enhanced. It is concluded that the formation of effective focal contacts is the concerted interaction between receptors recruitment and ligand occupy. This interaction plays an important role in transducing mechanical stimuli into intracellular signals.

为了探讨机械拉伸应变对人肺上皮细胞表面整联蛋白α3 、α5和 β1分布的调控作用 ,建立了体外周期性拉伸应变装置 ,并应用胞外基质蛋白———纤连蛋白 (Fn)、胶原蛋白Ⅳ (ColⅣ )裱衬基底膜 ,激光共聚焦显微镜分析了在应变为 15 % ,频率为 4 0次 /min的拉伸刺激下 ,正常人肺上皮细胞H72 7表面α3 、α5和 β1整联蛋白的再分布 .结果表明 :在人肺上皮细胞H72 7中 ,α3 、α5和 β1整联蛋白是对拉伸应变敏感的膜受体 ,周期性拉伸刺激可诱导其激活 ,使之发生分布的重组 ,并向基底层转移 ,形成局部粘附连接 ,增强了整联蛋白受体与其特异性配体的结合能力 .结果提示 :一个有效的局部粘附连接的形成是受体聚集和配体占据共同启动的一个协调反应 ,该反应可能参与了细胞响应机械应力的起始过程 ,可能进一步通过力 化学信号的耦合或张力整合的形式 ,最终对细胞的生物学行为产生影响

 
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