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Objective To study the relation ship between symptoms and pathogens of vulvitis in prepubertal girls. Methods The symptoms of patients were observed and inflammation cells, clue cells, Candida, pinworm ovum, N.gonorrhea(Ng), U. urealyticum(Uu), C. tracholitic(Ct) in the vulval secretion were detected. The plasma from lesion for P. pallidum was examined and rapid plasma reagin(RPR) was tested with blood serum. Results The symptoms of the vulvitis of 93 prepubertal girls involved increase of discharge or...

Objective To study the relation ship between symptoms and pathogens of vulvitis in prepubertal girls. Methods The symptoms of patients were observed and inflammation cells, clue cells, Candida, pinworm ovum, N.gonorrhea(Ng), U. urealyticum(Uu), C. tracholitic(Ct) in the vulval secretion were detected. The plasma from lesion for P. pallidum was examined and rapid plasma reagin(RPR) was tested with blood serum. Results The symptoms of the vulvitis of 93 prepubertal girls involved increase of discharge or purulent, abnormal smell, vaginal itching, dysuria, frequent micturition. The primary signs are vaginal mernbrance congestion, skin redness or erythema of vulva. The positive results of pathogens examination are 14 gram-negative or gram-positive bacteria, 8 Candida, 9 pinworm ovum, 5 Ng, 5 Ct, 22 Uu, 3 RPR and 1 P. pallidum respectively. Conclusion The results suggest that the pathogens of the vulvitis in prepubertal girls are mainly gram-negative or gram-positive bicteria, Candida and pinworm. Perhaps the anatomy of prepubertal girl associated with microorganisms infection. Although the prepubertal girls with vulvitis have no experience of being abused, their parents have history of STD. And it shows that close family contact, poor sanitation and bad presonal habit are responsible for the vulvitis in prebertal girls. It is noteworthy that the symptoms of vulvitis in prepubertal girls has no specific characteristics except infected by N.gonorrhea and P.pallidum. Especially pinworm vulvitis were often misdiagnosed as generative vulvitis.

目的探讨女童外阴炎临床表现与病因的关系。方法观察患有外阴炎女童的临床表现,取外阴分泌物检查炎性细胞、线索细胞、念珠菌、蛲虫卵、淋球菌(Ng)、沙眼衣原体(Ct)、解脲脲原体(Uu)。取皮损渗出液和静脉血分别检查梅毒螺旋体和RPR。结果女童外阴炎的主要症状有外阴分泌物增多,或脓性,有异味,外阴瘙痒、尿疼、尿频。临床体征有外阴黏膜充血,外阴或肛周皮肤发红或红斑。病原学检查阳性结果分别是G-或G+细菌14例,念珠菌8例,蛲虫卵9例,Ng5例,Ct4例,Uu22例,RPR3例,梅毒螺旋体1例。结论临床表现和病原学结果显示引起女童外阴炎的病因主要有G-或G+细菌、念珠菌、蛲虫。女童生殖道结构特点可能是其易受外界病原菌感染的主要原因。患有性病病原性外阴炎的女童,虽无性疟待史,但其父亲或母亲多有性病史,提示家庭密切接触或不良的环境卫生和个人卫生习惯可致女童性病性外阴炎。值得注意的是:除淋菌和梅毒感染者的临床症状具有特征性,其他几种病原菌所致的女童外阴炎,其临床表现特异性较差,尤其是蛲虫所致的外阴炎常被误诊为性病性外阴炎。

Objective To explore the relationship for women with reproductive tract human papillomaviruses (HPV) infection and other reproductive tract pathogen infection. Method There were 950 women with reproductive tract infection symptoms to join it. Pathogen examinations were done and which included vagina trichomonad, candida albicans, chlamydia trachomatis, ureaplasma urealyticu, gonorrhoea, HPV6,11,16,18 and syphilis. The single factor logistic recurrence analysis was used, and the relationship of women...

Objective To explore the relationship for women with reproductive tract human papillomaviruses (HPV) infection and other reproductive tract pathogen infection. Method There were 950 women with reproductive tract infection symptoms to join it. Pathogen examinations were done and which included vagina trichomonad, candida albicans, chlamydia trachomatis, ureaplasma urealyticu, gonorrhoea, HPV6,11,16,18 and syphilis. The single factor logistic recurrence analysis was used, and the relationship of women with HPV6,11,16,18 infection and other reproductive tract pathogen infection was analysed. Results The positive rate of reproductive tract infection HPV6,11 combining ureaplasma urealyticu infection was high. The correlation between HPV6,11 infection and ureaplasma urealytic infection was evident(P=0.01). There were certain correlations between reproductive tract infection HPV6,11,16,18 infection and other reproductive tract pathogeny infection, and which was ureaplasma urealytic infection (P=0.02), chlamydia trachomatis infection(P=0.04) and syphilis infection(P=0.01). Conclusions The reproductive tract HPV infection on women is related to ureaplasma urealytic infection, chlamydia trachomatis infection and syphilis infection. The mechanism between HPV and other reproductive tract pathogen infection is worth to be probed in further.

目的探讨妇女生殖道人乳头瘤病毒(HPV)感染与生殖道其他病原体感染的相互关系及危险因素分析。方法共计950名伴有各种生殖道感染症状与体征的妇女,病原体的检测包括阴道滴虫、白色念珠菌、沙眼衣原体、解脲支原体、淋病奈瑟菌、HPV和梅毒。用单因素Logistic回归分析HPV感染与其他生殖道病原体感染的相关性。结果生殖道HPV6、11感染合并解脲支原体阳性检出率较高,HPV6、11感染与解脲支原体感染有明显相关性(P=0.01),HPV6、11、16、18感染与解脲支原体(P=0.02),沙眼衣原体(P=0.04),梅毒(P=0.01)感染有一定的相关危险性。结论妇女生殖道HPV感染与解脲支原体、沙眼衣原体、梅毒的感染有关。HPV与生殖道病原体感染相互作用的机制值得进一步探讨。

 
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