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   细胞癌 在 妇产科学 分类中 的翻译结果: 查询用时:0.034秒
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细胞癌
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86 cases of malignant tumors of testis were collected during the past 20 years(dating from 1958). Among them, 52 cases (60%) were classified as germ cell carcinomas (formerly known as seminoma). According to the morphologyand the differentiation of the tumor cells, 4 types can be classified, namely: (1) large cell type, (2) small cell type, (3) undifferentiated type and (4) mixed type. The incidence is most predominant in the 21-50 years age group (87%). The site of tumor is more frequent on the right side than...

86 cases of malignant tumors of testis were collected during the past 20 years(dating from 1958). Among them, 52 cases (60%) were classified as germ cell carcinomas (formerly known as seminoma). According to the morphologyand the differentiation of the tumor cells, 4 types can be classified, namely: (1) large cell type, (2) small cell type, (3) undifferentiated type and (4) mixed type. The incidence is most predominant in the 21-50 years age group (87%). The site of tumor is more frequent on the right side than on the left side, while bilateral growths are rare. Cryptorchidy is present in 15% of cases. 22% were metastasized. Survival rates for 1 year, 5 years, and 10 years are 97%, 38% and 19% respectively.

本文对睾丸生殖细胞癌52例作病理分析、按生殖细胞癌组织的形态分为四型。即1,大细胞型生殖细胞癌。2.小细胞型生殖细胞癌,3.未分化型生殖细胞癌及4.混合型生殖细胞癌。生殖细胞癌在本组占睾丸恶性肿瘤的60%。年龄以21~50岁最常见,占87%。部位以右侧多于左侧,双侧少见。隐睾与肿瘤有一定关系、占15.3%。转移率在本组为22%。生存率一年为97%,五年为38%,十年为19%。

1.In a series of nitrosamine induced changes from hyperplasia,precancerous hyper- plasia to carcinoma in the routine forestomach,the ultrastructural Changes found are only quantitative;a specific morphologic differences are not discernible between the orecancer cells and cancer cells. 2.The specific changes in cancer cells include enlargement of the nucleus,irregula- rity of nuclear membrane,abundance of nuclear chromosome,accumulation of me- tachromic granules in the periphery of the nucleus,enlargement of...

1.In a series of nitrosamine induced changes from hyperplasia,precancerous hyper- plasia to carcinoma in the routine forestomach,the ultrastructural Changes found are only quantitative;a specific morphologic differences are not discernible between the orecancer cells and cancer cells. 2.The specific changes in cancer cells include enlargement of the nucleus,irregula- rity of nuclear membrane,abundance of nuclear chromosome,accumulation of me- tachromic granules in the periphery of the nucleus,enlargement of the nucleoli and appearance of double and multiple nucleoli.In the cytoplasm,there were swelling and vesicular degeneration of the mitochondria,dilatation and vesicular degeneration of the endoplasmic reticulum,irregular distribution of the tensile fibrils,thickening and enlargement of fascicles and varying thickness and breaking of the basal lamella, All these changes to-gether with the maldevelopment of the desmosome constitute the ultrastructural morphologic basis of cancer cell infiltration and metastasis. 3.The appearance of keratin granules in cancer cells marks a tendency towards maturation,a characteristic of squamous cell carcinoma.Keratin granules are the product,of cell metabolism,and mostly are round but may be irregular in shape and size;they become enlarged as they approach the surface of the lesion. 4.Lymphocytes infiltrate between the hyperplastic basal ceils and cancer cells.A zone of hollow seen around some lymphocytes may be an indication of a slight cyto- lysis. 5.For further understanding of the morphologic characteristics of cancerigenesis,a comparison of electron and light microscopy and observations of dioxivesin embedd- ing and thick slides stained with hematoxylin and eosin may result in greater accura- cy.

1.用亚硝胺诱发小鼠前胃肿瘤发生过程中,从增生、癌前变到癌、在亚微结构上未见质的不同,仅是由轻到重,由不明显到明显的量的变化。目前在电镜下还没找到癌前细胞和癌细胞在形态方面的特异性变化。2.癌细胞的特征是核大、核膜不规则,核内常染色质丰富,异染色质的团块向周边积聚,以及核仁变大,出现双核仁或多核仁。胞质内线粒体肿胀及空泡样变,内质网扩张或呈空泡性变,张力原纤维分布不均匀,有的变粗而为大的束状结构;基底板厚薄不均,并发生断裂等现象。这些改变加上桥粒发育不良,为癌细胞浸润转移提供了超微结构形态学依据。3.癌细胞中角质颗粒的出现是表明细胞向成熟方向发展,是鳞状细胞癌的细胞特征。角质颗粒是一种代谢产物,多数为圆形,也有不规则形,大小不一,可见到由小颗粒增长变为大颗粒的过程,且越向表层颗粒越大。4.淋巴细胞侵入增生的基底细胞和癌细胞之间,个别淋巴细胞周围呈空晕状态,是否为轻度溶解细胞的现象、尚待进一步验证。5.为了深入了解上皮癌变的形态特征,通过光镜检查,与超微结构的对比观察,必要时与环氧树脂厚切片 H、E 染色切片后光镜观察对比,可以得到比较正确的结果。

The ConA receptors in normal and hyperplastic esophageal epithelia, carcinoma in situ, and Grade Ⅰ-Ⅲ squamous cell carcinoma are reexamined at the light microscope level. Receptors were found on the plasmalemma of superficial and prickle cells of normal esophageal epithelia. Some nuclei on the basal and prickle cell layers of hyperplastic esophageal epithelia have abundant ConA receptors. The nuclear membrane on cancer cells of Grade Ⅰ-Ⅲ squamous cell carcinoma has more compact ConA receptors with a rise of...

The ConA receptors in normal and hyperplastic esophageal epithelia, carcinoma in situ, and Grade Ⅰ-Ⅲ squamous cell carcinoma are reexamined at the light microscope level. Receptors were found on the plasmalemma of superficial and prickle cells of normal esophageal epithelia. Some nuclei on the basal and prickle cell layers of hyperplastic esophageal epithelia have abundant ConA receptors. The nuclear membrane on cancer cells of Grade Ⅰ-Ⅲ squamous cell carcinoma has more compact ConA receptors with a rise of dedifferentiation degree.

在光学显微镜水平上,再次观察了正常及增生食管上皮、原位癌及Ⅰ~Ⅲ级鳞状细胞癌的ConA受体。在正常食管上皮,表浅细胞及棘细胞的质膜上可见受体。在增生食管上皮,底层细胞和棘细胞的一些胞核有丰富的ConA受体。在Ⅰ~Ⅲ级鳞状细胞癌,随着癌细胞间变程度的增加,癌细胞核膜上的ConA受体更为密集。

 
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