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   细胞癌 在 口腔科学 分类中 的翻译结果: 查询用时:0.052秒
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  cell carcinoma
Regulation of matrix metalloproteinase-9 transcription in squamous cell carcinoma of uterine cervix: the role of human papilloma
      
Matrix metalloproteinase-9 (MMP-9) plays an important role in initiation and progression of squamous cell carcinoma (SCC) of human uterine cervix.
      
Extended terminal deletions (56%) prevailed over shorter internal and multiple deletions and dominated (65%) in the most aggressive histopathological kidney cancer subtype, clear-cell carcinoma.
      
Semiquantitative RT-PCR revealed elevated transcription of RHOA in tumors (45 cases of breast cancer, renal cell carcinoma, and epithelial ovarian carcinoma; p >amp;lt; 10-4).
      
The NOLA2 and RPS3A genes as highly informative markers of human squamous cell carcinoma of lung
      
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  cell carcinomas
To reveal early genetic alterations of chromosome 6 that are important for CC progression, we analyzed the loss of heterozygosity (LOH) in DNAs from 45 CIN cases, 47 microcarcinomas, and 19 invasive squamous cell carcinomas stage IB.
      
No change in the reactivity for HBGA was detected in the stratified epithelium overlying squamous cell or basal cell carcinomas, whereas a considerable loss of LAMPs was detected.
      
We investigated 37 head and neck squamous cell carcinomas (HNSCC) at different stages, using immunohistochemical staining for CD4+ infiltrates and real-time reverse transcription polymerase chain reaction (RT-PCR) detection of CD4 mRNA.
      
Signet ring cell carcinomas frequently contained strong CD97stalk and CD55-staining.
      
Effect of the Hypoxic Cell Sensitizer Isometronidazole on Local Control of Two Human Squamous Cell Carcinomas after Fractionated
      
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  carcinoma
Immunohistochemical analysis revealed a high expression level of hSef in kidney, testis, and the corresponding carcinoma tissues.
      
Effect of down-regulating VEGF on proliferation of colon carcinoma cell HT-29
      
Cancer-related genes harbored in the loss regions containing a high frequency of hepatocellular carcinoma (HCC) were selected.
      
The purified 19peptide directly inhibited proliferation and migration of murine B16 melanoma cells, SMMC-7721hepatoma carcinoma cells and human umbilical vein endothelial cells (HUVEC).
      
We recognized and honoured the important contributions of these Chinese pioneers in portal hypertension, recurrent pyogenic cholangitis, hepatocellular carcinoma and liver transplantation.
      
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  cell carcinoma cell
To investigate the effects of ATRA, acitretin and tazarotene on the growth and apoptosis of human tongue squamous cell carcinoma cell line Tca8113.
      
In contrast, the spindle-cell carcinoma cell line CarB exhibited significantly higher PDE activity, concomitant with the lowest cAMP level.
      
Detection of antigenic differences and similarities between human transitional cell carcinoma cell lines using rabbit antisera
      
A new human transitonal cell carcinoma cell line has been established in long term tissue culture.
      
Establishment of three human renal cell carcinoma cell lines (SMKT-R-1, SMKT-R-2, and SMKT-R-3) and their characters
      
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Abstract DMBA can induce buccal squamous cell carcinoma of golden hamster,the process was divided into precancerosis and carcinogenesis stages,The longer DMBA was used the stronger carcinogenicty was.A5g/L DMBA in acetone was painted on hamster cheek pouch three times a week,for 6,9 and 12 weeks respectively.Histology appearances was recorded,37.5% of which were simple hyperplasia and 62.5%were slightly dysplasia in 6 weeks of DMBA treated hamster.25% of which were severedly dysplasia and 75% were preivasive...

Abstract DMBA can induce buccal squamous cell carcinoma of golden hamster,the process was divided into precancerosis and carcinogenesis stages,The longer DMBA was used the stronger carcinogenicty was.A5g/L DMBA in acetone was painted on hamster cheek pouch three times a week,for 6,9 and 12 weeks respectively.Histology appearances was recorded,37.5% of which were simple hyperplasia and 62.5%were slightly dysplasia in 6 weeks of DMBA treated hamster.25% of which were severedly dysplasia and 75% were preivasive carcinoma in 9 weeks of DMBA treated hamsters.12.5% of hamsters which induced by DMBA in 12 weeks were preivasive carcinoma and 87.5%were microinvasive carcinoma,In the 18 weeks group (hamsters were induced by DMBA until the 12th weeks)all of the hamster were well differentiated squamous cell carcinoma.Acetone has not the carcinogenicity.The hamster cheek pouch cancer induced by DMBA is similar to human oral buccal squmaous cell carcinoma in clincal and histology.This model is a simple,convenient.stable and good repetition one,also is a useful expreiment animal oral cancer model.

用5g/L二甲基苯并蒽(DMBA)丙酮溶液涂布地鼠颊囊粘膜每周3次,共6~12周,观察癌变全过程。结果用药6周后有37.5%地鼠颊囊粘膜表现为单纯性上皮增生,62.5%为非典型性上皮增生;9周后有25%为非典型性上皮增生;而75%为原位癌;12周后有12.5%为原位癌,87.5%为早期鳞状细胞癌;用药至第12周而观察到18周时,所有动物均为高分化鳞状细胞癌。丙酮无致癌作用。DMBA所诱导的地鼠颊囊癌类似于人类口腔颊部鳞状细胞癌,方法简便,诱癌时间较稳定,病理过程与人类相似,是一个实用性较强,又比较理想的口腔癌动物模型。

Abstract Twelve pleomorphic adenomas and eight myoepitheliomas were studied by an immunohistochemistry with antiactin,myosin, S-100 protein and glial fibrillary acidic protein(GFAP) antibodies. The results indicated that in pleomorphic adenoma, actin, myosin, S-100 protein and GFAP expression were seen in the stellate, triangle cells in the myxoid region and in the basal layer cells of the double-layered duct structure, these tumor cells were regarded as neoplastic myoepithelial cells,the squamous metaplasia...

Abstract Twelve pleomorphic adenomas and eight myoepitheliomas were studied by an immunohistochemistry with antiactin,myosin, S-100 protein and glial fibrillary acidic protein(GFAP) antibodies. The results indicated that in pleomorphic adenoma, actin, myosin, S-100 protein and GFAP expression were seen in the stellate, triangle cells in the myxoid region and in the basal layer cells of the double-layered duct structure, these tumor cells were regarded as neoplastic myoepithelial cells,the squamous metaplasia cells were positive in the tumors; myoepithelioma cells were identified by weak to intense actin, myosin, S-100 protein and GFAP positive reaction. This fact suggested that (1) in pleomorphic adenoma, neoplastic myoepithelial cells could transform into the squamous metaplasia cells, if malignant changes occur, they will become squamous cell carcinoma by squamous metaplasis;(2) neoplastic myoepithelial cells of pleomorphic adenoma were the same immunofeature as myoepithelioma cells, more than 5%~10% of ductal components of pleomorphic adenoma is principle differential from pleomorphic adenoma and myoepithelioma.

采用抗平滑肌的肌动蛋白(actin)、肌球蛋白(myosin);S-100蛋白以及胶质纤维酸性蛋白(GFAP)抗体研究涎腺肌上皮瘤和多形性腺瘤。结果发现,肌上皮瘤细胞对上述4种抗体呈不同程度的阳性反应。在多形性腺瘤中,双层导管结构的外周瘤细胞,成片增生的梭形细胞以及粘液样区域内的星形、三角形瘤细胞对上述4种抗体反应阳性,鳞状化生的瘤细胞也反应阳性,导管内层瘤细胞对上述4对抗体反应阴性。本文研究结果表明:①在多形性腺瘤中,肿瘤性肌上皮细胞可以出现鳞状化生,可以通过鳞状化生形成鳞状细胞癌,成为恶性多形性腺瘤中鳞状细胞癌的组织来源;②肌上皮瘤和多形性腺瘤中肿瘤性肌上皮细胞具有相同的免疫特性和分化趋向,用上述抗体不能鉴别这两种肿瘤。

Abstract Established a sensitive and specific method which can amplify multiple types HPVs DNA by degenerate primers PCR technique. The technique specifically amplify five types HPV (6, 11, 16, 18, 33)at least, without no-specific amplification of human DNA. Amplified HPVs DNA in formalin-fixed paraffinembedded tissues of oral squamous cell carcinoma and oral leukoplakia with carcinomatous transformation by this technique, the positive cases in these two groups are 22/30 and 23/30 respectively. The results indicated...

Abstract Established a sensitive and specific method which can amplify multiple types HPVs DNA by degenerate primers PCR technique. The technique specifically amplify five types HPV (6, 11, 16, 18, 33)at least, without no-specific amplification of human DNA. Amplified HPVs DNA in formalin-fixed paraffinembedded tissues of oral squamous cell carcinoma and oral leukoplakia with carcinomatous transformation by this technique, the positive cases in these two groups are 22/30 and 23/30 respectively. The results indicated that HPVs might play an important role in the carcinogenesis of oral squamous cell carcinoma.

建立了一种简并引物PCR技术扩增多型人乳头瘤病毒(HPV)DNA的方法,本方法至少可以特异地扩增HPV6,11,16,18及33。将其用于扩增福尔马林固定石蜡包埋口腔鳞状细胞癌及癌变白斑组织中的HPVsDNA,其阳性例数分别为22/30,23/30例。本研究表明HPV极可能参与了口腔鳞状细胞癌和癌变白斑的癌发生。

 
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