Results: The positive expression rates of mucin MUC1 and MUC2 in normal colorectal mucosa were 0 and 100%, respectively, but the positive expression rates of mucin MUC1 and MUC2 in 126 cases of colorectal carcinoma were 42.1% and 36.5%, respectively (P< 0.01);
In 5 colorectal cancer cell lines, in which the percentage of dead cells was determined 4 days after 30 Gy irradiation in the presence of doranidazole,the percentage of dead cells was significantly increased from 18.7%,21.9%,16.7%, 15.7% and 19.5% to 36.4%,33.8%,28.9%,22.2% and 27.0% respectively.
Methods Human colon adenocarcinoma cell line HCT116 was treated with different concentration of indomethacin for 24 h and CDK 2,CDK 4, Bcl 2, Bax and p21 WAF1/CIP1 protein were detected by Western blot.
Results At a concentration of 10 μg/ml,NK4 factor suppressed human colon cancer cells,breast cancer cells,mouse melanoma cells and human oophoroma cells that invaded the reconstituted basement membrane by 56.4%,56.3%,56.1% and 45.0%.
A peroral pretreatment of mice with the crude and purified samples of rauvolfian (RS and RSP) was found to decrease colonic macroscopic scores, the total area of damage, and tissue myelope roxidase activity in colons as compared with a colitis group.
Among the hypothyroidism patients, 56.6% had decreased gastric motility, especially in gastric body and greater gastric curvature; 86.6% had decreased colonic motility, especially in the left half of the colon.
Insulin-like growth factor binding-protein-7 (IGFBP7) was obtained from our previous colonic adenocarcinoma (CRC) and normal mucosa suppression subtraction hybridization (SSH) cDNA libraries.
The piglets were cannulated at the end of the ileum which allowed estimation of the ileal and colonic mineral absorption.
Background: Beside their role as the main energy source in the colonic mucosa, short chain fatty acids were found to act as potent antiproliferative and differentiation agents in various cancer cell lines.
Modality of Cell Death Induced by Foscan?-Based Photodynamic Treatment in Human Colon Adenocarcinoma Cell Line HT29
Covalent binding of a synthetic DNA fragment with eukaryotic transcription factor NF-κB has been studied in lysates of human colon carcinoma HCT-116 cells.
Organoid Culture of Human Colon Adenocarcinoma as a Model of Local Intercellular Interactions
The DGM-1 anti-proliferative activity was comparable with that of doxorubicin on three models: cell lines of murine melanoma B16-F1 and human breast cancer MCF-7 (HTB-22) and human colon cancer HT-29 (HTB-38).
In this study, the release of mitochondrial proapoptotic intermembrane space proteins induced by exogenous C2-ceramide in human colon carcinoma (HT-29) cell line was investigated.