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injectable
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  可注射
    Experimental Study of Injectable Hydroxyapatite Cement for the Augmentation of Mechanical Properties in the Osteoporotic Femoral Intertrochanteric Area
    可注射性羟基磷灰石骨水泥增强疏松转子间区力学性能的实验研究
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    A preliminary study of injectable tissue-engineered bone
    可注射性组织工程骨的初步研究
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    Evaluation on the Safety of Injectable Collagenous Material
    可注射性胶原生物材料的安全性评价
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    A study of injectable autogenous tissue-engineered bone
    可注射性自体组织工程骨的研究
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    A study of injectable tissue-engineered bone
    可注射性组织工程骨的研究(英文)
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  “injectable”译为未确定词的双语例句
    The influence of the injectable osteoinductive material with rhBMP 2 and bFGF on the proliferation and ultrastructure of marrow stromal cell of rabbit
    复合骨形态发生蛋白2及碱性成纤维细胞生长因子注射型骨修复材料对兔骨髓基质细胞增殖和超微结构的影响
短句来源
    Study on Injectable Bioactive Bone Repairing Material of Nano-hydroxyapatite and Polyamide-66 Composite
    注射型纳米羟基磷灰石/聚酰胺生物活性骨修复材料的研究
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    Injectable osteoinductive material in inducing ectopic bone formation
    注射型骨修复材料诱导成骨活性的研究
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    Study on the Biocompatibility of Injectable PLGA Microspheres Loading Estradiol
    注射用雌二醇聚乳酸羟基乙酸缓释微球生物相容性研究
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    Transforming Growth Factor-β1-Loaded Fibrin Sealant Promote Bone Marrow Mesenchymal Stem Cells to Contract Injectable Tissue Engineering Cartilage in vivo
    负载转化生长因子β1的生物蛋白胶促进骨髓间充质干细胞体内构建组织工程软骨
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  injectable
The frequency of treatment with injectable depot neuroleptics in U.K.
      
Injectable treatments were often prescribed for mental illness, especially by private general practitioners (GPs).
      
The potential anti-arrhythmic effect of some solvents, used in the preparation of injectable solutions, is stressed.
      
Spectinomycin is now available as a new single-dose injectable antibiotic for the treatment of gonorrhea.
      
Clindamycin is available in oral dosage forms and is just now being made available as clindamycin phosphate, a new injectable form of clindamycin.
      
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Objective To observe histomorphology of neo-cartilage obtained with tissue-engineering by combining calcium alginate gel and in vitro cultrue of chondrocytes. Methods Articular chondrocytes from the knee joints of 2-week-old New Zealand white rabbits were harvested, expanded in cell culture, and following the second generation of the culture, the chondrocyte suspension was mixed with calcium alginate gel resulting in a cell density of 5× 10 6/ml. Finally the mixture, which contained 1% sodium alginate,...

Objective To observe histomorphology of neo-cartilage obtained with tissue-engineering by combining calcium alginate gel and in vitro cultrue of chondrocytes. Methods Articular chondrocytes from the knee joints of 2-week-old New Zealand white rabbits were harvested, expanded in cell culture, and following the second generation of the culture, the chondrocyte suspension was mixed with calcium alginate gel resulting in a cell density of 5× 10 6/ml. Finally the mixture, which contained 1% sodium alginate, 40 mmol/L calcium gluconate, 0.135 mol/L NaCl, 0.1 mol/L K 2HPO 4 and 5× 10 6 chondrocytes per milliliter, were injected into the dorsal subcutaneous tissue in rabbits of experimental groups (A and B). Animals of the control groups (C and D) were injected with calcium alginate without chondrocytes or chondrocytes without calcium alginate. Specimens were harvested at the 2nd and 4th week after injection, and stained with HE and toluidine blue. Results In the HE stained specimens in the experimental groups, proliferation of chondrocytes was demonstrated at the 2nd week and the formation of neo-cartilage at the 4th week after injection of calcium alginate chondrocyte-composite. Toluidine blue stained specimens showed positive staining of chondrocytes and cartilage matrix of neo-cartilage. In some animals injected with chondrocytes without calcium alginate, relative small amount of neo-cartilage was also formed and no neo-cartilage was observed in animals injected with calcium alginate without chondrocytes. Conclusion Injectable calcium alginate-chondrocyte-composite can induce tissue engineered neo-cartilage in allogenic animal.

目的 对经体外培养的软骨细胞与藻酸钙凝胶载体复合形成的组织工程性软骨进行组织形态学观察。方法 取 2周龄新西兰白兔的膝关节软骨细胞,经体外培养两次传代后与藻酸钠溶液复合,使细胞密度为 5× 10 6/ml、 NaCl 0.135 mol/L、 K 2HPO 4 0.1 mol/L、藻酸钠的质量分数为 1%,然后注入葡萄糖酸钙使终浓度为 40 mmol/L。在实验组 (A、 B组 )兔的背部皮下注入复合藻酸钙载体的软骨细胞悬液,对照组 (C、 D组 )动物或注入无载体的软骨细胞悬液或注入无细胞的藻酸钙载体,分别于注射后第 2周、第 4周取材,进行 HE和甲苯胺蓝染色。结果 实验组,于注射复合软骨细胞的藻酸钙凝胶载体第 2周时, HE染色结果显示皮下注射点出现大量软骨细胞增殖,第 4周时有软骨组织形成;甲苯胺蓝染色见有软骨细胞和软骨基质形成。在注入无载体的软骨细胞悬液组 (C组 ),部分动物的皮下注射点有少量软骨组织形成,而在注入无细胞的藻酸钙载体组 (D组 )则未见软骨形成。结论 应用可注射性藻酸钙凝胶载体复合软骨细胞可在同种异体动物体内形成新生软骨组织。

AIM To study the feasibility of the formation of allogeneic tissue engineered cartilage in immunocompetent animal and to verify that the material used in our experiment has the ideal features as tissue engineering biomaterial. METHODS Fresh newborn rabbits' articular cartilages were obtained under sterile condition (<6 h after death) and incubated in the sterile 3 g·l -1 type Ⅱ collagenase solution. After digestion of 8~12 h, the solution was filtered through a 150 micron nylon mesh and centrifuged,...

AIM To study the feasibility of the formation of allogeneic tissue engineered cartilage in immunocompetent animal and to verify that the material used in our experiment has the ideal features as tissue engineering biomaterial. METHODS Fresh newborn rabbits' articular cartilages were obtained under sterile condition (<6 h after death) and incubated in the sterile 3 g·l -1 type Ⅱ collagenase solution. After digestion of 8~12 h, the solution was filtered through a 150 micron nylon mesh and centrifuged, then the chondrocytes were washed twice with phosphate buffered saline (PBS) and mixed with the biomaterial to create a final cell density of 5×10 7 ml -1 . The resulting cell biomaterial admixture was injected subcutaneously 0.3 ml each point, and the control groups were injected with only the biomaterial or the suspension of chondrocyte with the density of 5×10 7 ml -1 . After 4, 6, 8 and 12 weeks, the neocartilages were harvested for analysis. RESULTS We touched the new nodes subcutaneously after 2 wk. In the sections of the samples harvested after 4 wk, we found that the matrix was secreted and the collagen formed. After 6 wk, the neocartilages were mature and the biomaterial was almost completely degraded. In the experiment groups we observed no obvious immune rejection response. On the contrary, in the control groups there were no neocartilage formed. CONCLUSION Biomaterial used in our experiment is a relatively ideal tissue engineering biomaterial. It's feasible to form allogeneic tissue engineered cartilage in an immunocompetent animal that provides an alternative minimum traumatic,malleable and injectable means for some clinic plastic and reconstructive operation.

目的 研究在有免疫力的动物体内形成同种异体工程化软骨的可行性 ;并验证本实验使用的生物材料聚氧化乙烯丙烯凝胶 (Copolymer gel of ethylene and propylene oxide)在组织工程研究中应用的可行性 .方法 无菌条件下取新生兔关节软骨 ,经 型胶原酶消化 ,将软骨细胞和生物材料复合成细胞浓度为 5× 10 7m l- 1的复合物并移植于兔皮下 ,同时设立单独注射细胞和材料两个对照组 .分别于 4,6 ,8,12 wk取材行大体观察 ,石蜡切片 HE染色 ,Safranin O染色 ,Masson's三色染色 ,了解软骨形成情况 .结果  2 wk后即可于皮下触及新生结节 ,4wk后取材即有基质分泌及胶原形成 .于 6 wk左右软骨接近成熟 ,生物材料基本吸收 .8,12 wk软骨基本接近正常软骨 .实验中未见明显的免疫排斥反应 .而对照组未见软骨形成 .结论 该实验使用的生物材料具有良好的生物相容性 ,可降解性 ,无细胞毒 ,是较理想的组织工程生物材料 ;应用该实验的方法可在有免疫力的动物体内形成同种异体工程化软骨 ,这为临床某些美容和重建手术提供了一种微创而可塑型的可能的...

目的 研究在有免疫力的动物体内形成同种异体工程化软骨的可行性 ;并验证本实验使用的生物材料聚氧化乙烯丙烯凝胶 (Copolymer gel of ethylene and propylene oxide)在组织工程研究中应用的可行性 .方法 无菌条件下取新生兔关节软骨 ,经 型胶原酶消化 ,将软骨细胞和生物材料复合成细胞浓度为 5× 10 7m l- 1的复合物并移植于兔皮下 ,同时设立单独注射细胞和材料两个对照组 .分别于 4,6 ,8,12 wk取材行大体观察 ,石蜡切片 HE染色 ,Safranin O染色 ,Masson's三色染色 ,了解软骨形成情况 .结果  2 wk后即可于皮下触及新生结节 ,4wk后取材即有基质分泌及胶原形成 .于 6 wk左右软骨接近成熟 ,生物材料基本吸收 .8,12 wk软骨基本接近正常软骨 .实验中未见明显的免疫排斥反应 .而对照组未见软骨形成 .结论 该实验使用的生物材料具有良好的生物相容性 ,可降解性 ,无细胞毒 ,是较理想的组织工程生物材料 ;应用该实验的方法可在有免疫力的动物体内形成同种异体工程化软骨 ,这为临床某些美容和重建手术提供了一种微创而可塑型的可能的手段 .

Objective: To develop injectable tissue-engineered bone. Methods: Bone marrow cells isolated from lilac bone of New Zealand rabbits were cultured and induced to differentiate Into osteoblasts. The osteoblasts were mixed with 20 g/L alginate sodium solution to generate osteoblasts/alginate composite with final cellular density of 5 × 10 6/ml. Calcium chloride was used as cross-linking agent. The osteoblasts/alginate composite was injected into the dorsal subcutaneous tissue of nude mice. The injected...

Objective: To develop injectable tissue-engineered bone. Methods: Bone marrow cells isolated from lilac bone of New Zealand rabbits were cultured and induced to differentiate Into osteoblasts. The osteoblasts were mixed with 20 g/L alginate sodium solution to generate osteoblasts/alginate composite with final cellular density of 5 × 10 6/ml. Calcium chloride was used as cross-linking agent. The osteoblasts/alginate composite was injected into the dorsal subcutaneous tissue of nude mice. The injected material with surounding tissue were examined with X-ray and histopathologic technique. Results: Four and eight weeks after injection, the hard knobbles were easily palpated under the dorsal skin of the animals. On X-ray photograph the knobbles showed calcified tissue image. In histological analysis, new bone formation was observed in the osteoblasts/alginate composite. The osteogenesis was in association with regenerated hematopoietic bone marrow. Conclusion: New bone tissue can be created through the injection of alginate sodium mixed with marrow stromal osteoblasts.

目的:探索可注射性组织工程骨的可行性。方法:从兔髂骨骨髓细胞中获取骨髓基质成骨细胞,将骨髓基质成骨细胞与20g/L藻酸钠溶液混合形成骨髓基质成骨细胞/藻酸钠复合物,使细胞的终浓度为 5×10 6/ml。将骨髓基质成骨细胞/藻酸钠复合物注射于裸鼠背部皮下,用氯化钙固化为凝胶体。结果:注射后4、8周注射物在裸鼠背部皮下形成硬结节,X线片均显示有明显成骨现象。组织学分析显示标本有大量新骨形成,并具有骨髓腔样结构。结论:应用藻酸钠复合骨髓基质成骨细胞可以通过注射方式在动物体内形成骨组织。

 
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