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transport distraction osteogenesis
相关语句
  牵张成骨
    Study of Reconstruction of Mandibular Condyle by Transport Distraction Osteogenesis in Monkeys
    运用输送盘牵张成骨术重建猴下颌髁突的实验研究
短句来源
    The Study of Reconstruction of Mandibular Condyle by Transport Distraction Osteogenesis in monkeys
    运用输送盘牵张成骨术重建猴下颌髁状突的实验研究
    Objective To evaluate the applicability and effectiveness of reconstruction of mandibular condyle by transport distraction osteogenesis in an animal model of rhesus monkeys.
    目的研究在猴颞下颌关节(TMJ)缺损动物模型上运用输送盘牵张成骨术重建髁突的可行性及其整复效果。
短句来源
    Conclusion A neocondyle with functional shape can be created by transport distraction osteogenesis,which suggested that this technique might be an alternative method in reconstruction of the condyle.
    结论输送盘牵张成骨术可以重建一个形态和功能都基本接近正常的髁突,这种技术可以作为一种整复TMJ缺损的新方法。
短句来源
  牵张成骨
    Study of Reconstruction of Mandibular Condyle by Transport Distraction Osteogenesis in Monkeys
    运用输送盘牵张成骨术重建猴下颌髁突的实验研究
短句来源
    The Study of Reconstruction of Mandibular Condyle by Transport Distraction Osteogenesis in monkeys
    运用输送盘牵张成骨术重建猴下颌髁状突的实验研究
    Objective To evaluate the applicability and effectiveness of reconstruction of mandibular condyle by transport distraction osteogenesis in an animal model of rhesus monkeys.
    目的研究在猴颞下颌关节(TMJ)缺损动物模型上运用输送盘牵张成骨术重建髁突的可行性及其整复效果。
短句来源
    Conclusion A neocondyle with functional shape can be created by transport distraction osteogenesis,which suggested that this technique might be an alternative method in reconstruction of the condyle.
    结论输送盘牵张成骨术可以重建一个形态和功能都基本接近正常的髁突,这种技术可以作为一种整复TMJ缺损的新方法。
短句来源
  “transport distraction osteogenesis”译为未确定词的双语例句
    Interoral Transport Distraction Osteogenesis for Reconstruction of Mandibular Defects
    口内牵引成骨重建下颌骨缺损的实验研究
    Objective:To study the effects of mesenchymal stem cells(MSCs) transplantation on new bone formation during transport distraction osteogenesis in a goat model of calvarial defect.
    目的 :研究自体骨髓间充质干细胞 (MSCs)对采用输送盘骨牵张术修复山羊颅骨缺损效果的影响。
短句来源
    Conclusion: Transplantation of autologous MSCs may have beneficial effect on bone formation following transport distraction osteogenesis in a goat model of calvarail defect.
    结论 :局部移植MSCs可能有促进牵张成骨的作用。
短句来源
    Bilateral condyles and articular discs were extirpated,and the technique of transport distraction osteogenesis was performed to reconstruct the condyle.
    方法选取6只成年恒河猴,手术截除双侧关节髁状突与关节盘,在下颌升支部行“L”形骨切开术形成骨输送盘,并安置自行研制的牵张器。
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Objective:To study the effects of mesenchymal stem cells(MSCs) transplantation on new bone formation during transport distraction osteogenesis in a goat model of calvarial defect.Method:8 adult goats were randomly divided into group A (n=4) and group B(n=4) .A calvarial defect and a transport disk were created in all animals , and a custom-made distractor was used for repairing the cranial defect. The group A goats were injected with autologous MSCs into the distracted region, whereas the group B...

Objective:To study the effects of mesenchymal stem cells(MSCs) transplantation on new bone formation during transport distraction osteogenesis in a goat model of calvarial defect.Method:8 adult goats were randomly divided into group A (n=4) and group B(n=4) .A calvarial defect and a transport disk were created in all animals , and a custom-made distractor was used for repairing the cranial defect. The group A goats were injected with autologous MSCs into the distracted region, whereas the group B with injection of physiological saline were used as controls. At 4 weeks after end of distraction, all animals were killed, and the distracted callus was obtained and prepared for histological and scanning electron microscopy analysis.Result:The new bone formation in the distraction gap at group A was superior to that of group B after transport osteodistraction for repairing of calvarial defect.Conclusion: Transplantation of autologous MSCs may have beneficial effect on bone formation following transport distraction osteogenesis in a goat model of calvarail defect.

目的 :研究自体骨髓间充质干细胞 (MSCs)对采用输送盘骨牵张术修复山羊颅骨缺损效果的影响。方法 :将成年雄性山羊 8只 ,随机分为A、B两组 ,每组 4只。在动物颅顶区制造全层颅骨缺损和输送盘 ,用自行研制的牵张器行输送盘骨牵张术修复颅骨缺损。牵张结束后 ,在A组动物牵张区注入体外培养的自体骨髓间充质干细胞 ;B组同期注入生理盐水作对照。在牵张结束后的第 4周处死A、B两组动物 ,取牵张区新生组织标本行组织学和扫描电镜分析。结果 :移植MSCs的A组动物牵张区新骨生成速度和钙化程度显著高于B组动物。结论 :局部移植MSCs可能有促进牵张成骨的作用。

PURPOSE:This study was aimed to set up a new method for reconstruction of maxillary defect with distraction osteogenesis through an animal experiment. METHODS: 11 adult goats were randomly divided into 2 groups (9 in the experimental group and 2 in the control group) in this study. 3 subgroups were set up in the experimental group based on the consolidation period. Other 2 goats were chosen as the control group. Maxillary defect was made firstly through partial maxillectomy for the experimental group....

PURPOSE:This study was aimed to set up a new method for reconstruction of maxillary defect with distraction osteogenesis through an animal experiment. METHODS: 11 adult goats were randomly divided into 2 groups (9 in the experimental group and 2 in the control group) in this study. 3 subgroups were set up in the experimental group based on the consolidation period. Other 2 goats were chosen as the control group. Maxillary defect was made firstly through partial maxillectomy for the experimental group. Length of the defects was from 12 to 14mm with an average of 12.7mm. A transport disc was then made through anterior Le Fort I osteotomy and it would be shifted backward for the closure of the defect. Only maxillary defect was made for the control group. Distraction was activated after a latency of 7 days at a rate of 0.4mm twice a day for 15-18 days. RESULTS: Bone defects in the maxilla were well repaired when the transport disc was distracted back to its original position. Radiology and histology demonstrated good new bone formation in the distraction gap. CONCLUSIONS: Transport distraction osteogenesis would be a reasonable method for reconstruction of maxillary defect. Supported by Shanghai Leading Academic Discipline Project(Y0203)and Shuguang Project of Shanghai Education Committee(02SG46).

目的:结合上颌骨的解剖生理特点,探讨采用传送盘回复式牵引成骨修复上颌骨缺损的可行性。方法:11只成年山羊,随机分为实验组和对照组。其中实验组9只,按固定期不同分为1、2、3个月组,每组3只;对照组2只。实验组山羊通过手术制作上颌骨前部节段性缺损,缺损长度12~14mm,平均大小12.7mm。同期制作缺损前方传送盘并使之后退,关闭缺损区,安置牵引器,通过牵引将传送盘回复原位。术后7天开始牵引,每天2次,持续15~18d,每次0.4mm,采用大体、影像学及组织学观察缺损区愈合情况。结果:传送盘牵引复位后,缺损区被新生骨修复,X线、三维CT及组织学检查显示,新骨形成良好,新骨形成方式符合传统牵引成骨的成骨方式。结论:传送盘回复式牵引成骨符合上颌骨的解剖特点,具有一定的临床可行性。

Objective:To observe the clinical results in correction of unilateral temporomandibular joint(TMJ) ankylosis accompanying with mandibular micrognathia using internal distraction osteogenesis simultaneously. Methods: Seven adult patients of unilateral TMJ ankylosis accompanying with mandibular micrognathia (13 sides of mandibular body) were treated simultaneously with internal distraction osteogenesis. Obstructive sleep apnea and hypopnea syndrome(OSAHS) was diagnosed in all patients preoperatively. The treatment...

Objective:To observe the clinical results in correction of unilateral temporomandibular joint(TMJ) ankylosis accompanying with mandibular micrognathia using internal distraction osteogenesis simultaneously. Methods: Seven adult patients of unilateral TMJ ankylosis accompanying with mandibular micrognathia (13 sides of mandibular body) were treated simultaneously with internal distraction osteogenesis. Obstructive sleep apnea and hypopnea syndrome(OSAHS) was diagnosed in all patients preoperatively. The treatment includs distraction osteogenesis of mandibular body and transport distraction osteogenesis for TMJ arthroplasty at the same time. Distraction was started on the 6th to 8th day after operation. The distraction rhythm and rate was one mm a day operated in 4 separate times. The patients underwent active mouth opening postoperatively. Distractors were kept in place for 3-5 months after completion of distraction and then removed. Mean distraction distance of the 13 sides of mandibular body was 17.1mm(ranged from 14 to 20 mm) and that of the 7 sides of TMJ was 16.4mm(ranged from 15 to 20mm). Results:After treatment, micrognathia of the 7 patients was corrected. OSAHS was cured in 6 patients. The mean range of mouth opening was increased from 8.1 mm to 39.9 mm and bone formation in the distraction gaps was observed. The mean following-up period was 34.3 months(ranged from 18 to 51 months). No recurrence of TMJ ankylosis or micrognathia was occurred. Conclusion:Unilateral TMJ ankylosis accompanying with micrognathia and OSAHS can be treated effectively by distraction osteogenesis simultaneously. The operation is simple with low risk. The course of treatment can be simplified and the operation times can be reduced.

目的:观察应用内置式颌骨牵引器对单侧颞下颌关节(temporomandibularjoint,TMJ)强直伴小颌畸形患者进行同期的牵引成骨治疗的临床疗效。方法:应用内置式颌骨牵引器,对7例单侧TMJ强直伴小颌畸形的成人患者进行同期的牵引成骨关节成形及下颌骨体(13侧)的牵引成骨治疗。术前经睡眠多导图仪(polysomnography,PSG)检查,7例患者均患有阻塞性睡眠呼吸暂停低通气综合征(obstructivesleepapneaandhypopneasyndrome,OSAHS),其中3例为重度OSAHS,另4例为轻、中度OSAHS。6例患者行双侧下颌骨体延长,1例患者行单侧下颌骨体延长。7例患者的TMJ强直均行牵引成骨关节成形术。手术包括两个术式:TMJ强直的牵引成骨关节成形术和小颌畸形的牵引成骨治疗。术后间歇期5~7天,牵引速度1mm/d,分4次进行。稳定期为3~5个月。术后即行开口训练。每一患者术前、术后均行X线头影测量及PSG检查。结果:所有患者术后OSAHS症状均减轻或消失。除1例术前重度者术后诊断为轻度外,其余6例患者术后PSG检查结果显示均已达到治愈标准。7侧关节强直经牵引成骨关节成形术矫...

目的:观察应用内置式颌骨牵引器对单侧颞下颌关节(temporomandibularjoint,TMJ)强直伴小颌畸形患者进行同期的牵引成骨治疗的临床疗效。方法:应用内置式颌骨牵引器,对7例单侧TMJ强直伴小颌畸形的成人患者进行同期的牵引成骨关节成形及下颌骨体(13侧)的牵引成骨治疗。术前经睡眠多导图仪(polysomnography,PSG)检查,7例患者均患有阻塞性睡眠呼吸暂停低通气综合征(obstructivesleepapneaandhypopneasyndrome,OSAHS),其中3例为重度OSAHS,另4例为轻、中度OSAHS。6例患者行双侧下颌骨体延长,1例患者行单侧下颌骨体延长。7例患者的TMJ强直均行牵引成骨关节成形术。手术包括两个术式:TMJ强直的牵引成骨关节成形术和小颌畸形的牵引成骨治疗。术后间歇期5~7天,牵引速度1mm/d,分4次进行。稳定期为3~5个月。术后即行开口训练。每一患者术前、术后均行X线头影测量及PSG检查。结果:所有患者术后OSAHS症状均减轻或消失。除1例术前重度者术后诊断为轻度外,其余6例患者术后PSG检查结果显示均已达到治愈标准。7侧关节强直经牵引成骨关节成形术矫治后,开口度均恢复正常。牵引间隙内成骨良好,未见感染及成骨不良等并发症发生。术后随访复查18~51个月,平均随访复查时间34.3个月。无小颌畸形及关节强直复发。结论:同期的牵引成骨治疗可有效矫治成人单侧TMJ强直伴小颌畸形及OSAHS。手术方法简便、风险小,能有效缩短治疗疗程,减少手术次数。术后开口训练对牵引间隙内的骨形成无不利影响。

 
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