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   rb gene protein 的翻译结果: 查询用时:0.012秒
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rb gene protein
相关语句
  rb基因蛋白
     Significance of p16 and Rb gene protein expression in primary lung cancers
     p16和Rb基因蛋白在肺癌中的表达
短句来源
     There was an inverse relationshipbetween the expression of p16 and Rb gene protein (P < 0.05).
     p16和Rb基因蛋白的表达呈显著负相关(P<0.05)。
短句来源
     Expressions of cyclin D1 and Rb gene protein in the gliomas and their clinical significance
     脑胶质细胞瘤cyclinD1和Rb基因蛋白表达及临床意义
短句来源
     Maybe there is a mechanism at gene translation level which leads to the inactivation of p16 or Rb gene protein.
     在翻译水平上也存在着引起 p16和Rb基因蛋白失活的可能机制。
短句来源
     Loss of Rb gene protein expression and P_(53) gene mutation in human testicular seminoma
     人类睾丸精原细胞瘤组织中P_(53)基因突变和Rb基因蛋白产物表达的缺失
短句来源
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  rb蛋白
     Rb gene protein positive expression rate in tumor tissues was 51.4%,which was also lower than that in normal mucosal tissues of colon and rectum (χ2=4.234,P< 0.05); Rb protein positive expression correlated significantly with lymph node metastasis(χ2=14.596, P< 0.05), but did not correlated with tumor cell differentiation( P >0.05).
     Rb蛋白阳性表达率在大肠腺癌组织中为51.4%,显著低于正常大肠黏膜组织(χ2=4.234,P<0.05),并与大肠腺癌淋巴结转移有关(χ2=14.596,P<0.05),但与组织分化程度无关(P>0.05);
短句来源
     Objective: To detemine the relationship between the expression of MTS1/p16, p53, Rb gene protein or proliferating cell nuclear antigen( PCNA) and clinicopathologic of human gastric cancer.
     目的:研究胃癌中 p16、 p53、 Rb蛋白及 PCNA表达与临床病理的关系。 方法:应用免疫组化 SP法对 63例胃癌组织中 p16、 p53、 Rb和 PCNA进行检测。
短句来源
  rb基因产物
     Significance of PCNA,p53,and Rb Gene Protein Expression in Mesenchymal Tumors
     间叶组织肿瘤中增殖细胞核抗原、p53、Rb基因产物表达及意义
短句来源
     Expression and prognosis of Rb gene protein in gastric cancer
     Rb基因产物表达与胃癌预后关系的探讨
短句来源
  “rb gene protein”译为未确定词的双语例句
     Significance of p16 and Rb Gene Protein Expression in Primary Gallbladder Carcinoma
     p16、Rb基因表达与原发性胆囊癌病理生物学行为及预后的关系
短句来源
     The Rb gene protein was detected in 30%,0 and 7% of the oral SCC,leukoplakia and lichen planus,respectively.
     Rb抗癌基因在口腔癌、白斑、扁平苔藓中表达的阳性率分别为 30 %、0和 7%。
短句来源
     After 48 hours incubation, the Rb gene protein expression of L78 cell-line was estimated by immunohistochemistry method; the Rb, the Cyclin D 1 gene proteins and the cell apoptosis were estimated by flow cytometry, and the correlation among them was studied.
     两组均培养 4 8小时后用免疫组织化学法检测 L78细胞中 Rb基因表达率 ,用流式细胞仪技术分别检测 Rb、Cyclin D1 基因表达率和肿瘤细胞凋亡率 ,并研究三者之间的相关关系。
短句来源
     Objective To investigate the alter expressions of cyclin D1 and Rb gene protein in gliomas, evaluate their role in tumorigenesis, growth, invasion and metastasis and progression from low grade to high grade, and provide theoretic basis for clinical diagnosis, therapy and evaluating prognosis.
     目的 通过检测脑胶质瘤中细胞周期调节蛋白 D1(cyclin D1)、视网膜母细胞瘤 ( Rb )基因蛋白表达,探讨 其在脑胶质瘤发生、生长和转移过程中,以及由低恶性度肿瘤向高恶性度肿瘤转化中的作用,为临床诊治和预后判断提供依据。
短句来源
     6 cases of normal brain tissues were taken as control group. The expressions of cyclin D1 and Rb gene protein in astrocytoma were detected quantitatively by Flow Cytometry (FCM). Results ① The FI of cyclin D1 protein in astrocytoma was higher and correlated with increasing histological grade (P<0.01).
     应用流式细胞术( FCM 分别定量检测 cyclin D1、 基因蛋白表达量。结果 ① Cyclin D1蛋白在各级星形细胞瘤中表达均增强,且 ) Rb阳性率均为 100%,但 cyclin D1蛋白的表达量( 值) FI随肿瘤恶性度的升高而明显增加。
短句来源
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  rb gene protein
Gossypol plasma levels were measured (n=8) and the modulation of the retinoblastoma (Rb) gene protein and Cyclin D1 was assessed by serial biopsies (n=4).
      


Immunohistochemical staining method(ABC method) is used to detect the Bcl 2,P53,P21 and Rb gene protein in 40 cases of primary brain gliomas and 5 cases brain tissue.Results showed:the positive rates of Bcl 2 protein,P53 protein expression were remarkably different in I to Ⅳ stage of brain gliomas.The expression of P21 protein,Rb protein was gradually increased from Ⅰ to Ⅳ stage of brain gliomas.Therefore...

Immunohistochemical staining method(ABC method) is used to detect the Bcl 2,P53,P21 and Rb gene protein in 40 cases of primary brain gliomas and 5 cases brain tissue.Results showed:the positive rates of Bcl 2 protein,P53 protein expression were remarkably different in I to Ⅳ stage of brain gliomas.The expression of P21 protein,Rb protein was gradually increased from Ⅰ to Ⅳ stage of brain gliomas.Therefore our data indicated the Bcl 2,P53,P21 and Rb gene were important in arising of gliomas,particularly Bcl 2,P53 gene.The expression of these gene were correlated with the degree of malignant of gliomas.Detection of expression of Bcl 2,P53,P21 and Rb gene may be a useful tool for diagnosis,distinguish diagnosis and asserted of malignant and prognosis.

采用原癌基因Bcl-2、P21及抑癌基因P53、Rb蛋白4种抗体,用ABC免疫组织化学方法对40例脑星形胶质瘤组织作免疫组化染色.结果发现:Bcl-2及P53基因表达在Ⅰ~Ⅳ级胶质瘤中阳性率有显著性差异,而且染色强度也有明显差异.P21、Rb基因表达在Ⅰ~Ⅳ级胶质瘤中呈上升趋势,但仅在Ⅰ~Ⅲ级、Ⅰ~Ⅳ级之间有明显差异.可以认为:Bcl-2、P53、P21、Rb在胶质瘤的发生中发挥一定的作用,尤其是Bcl-2、P53基因,这些基因蛋白的表达与胶质瘤恶性程度有关.测定胶质瘤中的Bcl-2、P53、P21、Rb蛋白对于胶质瘤的诊断、鉴别诊断以及判断肿瘤的恶性程度与预后均有一定意义.

Objective To find the expression and significance of gene changes which were related to cell - cycle regulato in gastric candia carcinma.Methods The immunohistochemical mehod(SP)was used to study the expression of p16and Rb proteins in 58 cases of gastric cardea carcinoma. Results For p16, the positive rates decreased with the progression ofthe pathological grade and invasion, while for Rb, the positive rates increased (P < 0.05). There was an inverse relationshipbetween the expression...

Objective To find the expression and significance of gene changes which were related to cell - cycle regulato in gastric candia carcinma.Methods The immunohistochemical mehod(SP)was used to study the expression of p16and Rb proteins in 58 cases of gastric cardea carcinoma. Results For p16, the positive rates decreased with the progression ofthe pathological grade and invasion, while for Rb, the positive rates increased (P < 0.05). There was an inverse relationshipbetween the expression of p16 and Rb gene protein (P < 0.05). Conclusion These results suggest that deletion of p16 andRb gene Protein expession is related with carcinogenesis of gastric cardia carcinoma, and Rb expression is negatively regulated by the functional of p16 gene protein.

目的探讨与细胞周期调节相关的基因p06和Rb基因在贲门癌中的表达及其意义。方法用SP免疫级化法对58例贲门癌进行p16和Rb基因蛋白的检测。结果随着贲门癌恶性程度的加重和浸润的加深,p16基因蛋白的阳性表达率逐渐降低,而Rb基因蛋白的阳性表达率逐渐升高(P<0.05)。p16和Rb基因蛋白的表达呈显著负相关(P<0.05)。结论p16和Rb基因蛋白的表达异常在贲门癌的发生发展中起重要作用。p16基因蛋白对Rb基因蛋白的表达具有负性调节作用。

Purpose To study the expression of p16 and Rb gene proteins in primary lung cancers. Method Eightynine cases of lung cancer were observed by immunohistochemistry. Results The loss of p16 protein in lung cancers was related to histological type, lymph node metastasis and progressive stage, while the loss of Rb protein only to histological type. The inverse correlation of p16 and Rb gene expression in lung cancers was confirmed. Conclusion The loss of p16 or Rb gene protein...

Purpose To study the expression of p16 and Rb gene proteins in primary lung cancers. Method Eightynine cases of lung cancer were observed by immunohistochemistry. Results The loss of p16 protein in lung cancers was related to histological type, lymph node metastasis and progressive stage, while the loss of Rb protein only to histological type. The inverse correlation of p16 and Rb gene expression in lung cancers was confirmed. Conclusion The loss of p16 or Rb gene protein is an important molecular event in lung cancers, and closely related to the block in the negative regulatory pathway of cell cycle.

目的:研究p16和Rb基因蛋白的表达与肺癌临床病理学特征的关系。方法:采用免疫组织化学方法对89例肺癌进行了p16和Rb蛋白的定位观察。结果:肺癌p16基因蛋白的总丢失率为472%(42/89),且与肺癌的组织学类型、淋巴结转移、临床病理分期有关。Rb基因蛋白的总丢失率为315%(28/89),与组织学类型有关。p16和Rb基因蛋白的表达存在着明显的互补性。结论:p16和Rb基因蛋白的丢失是肺癌发生发展中重要的分子事件,与细胞周期G1→S期的负反馈调节环路中断关系密切。

 
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