The serum concentrations of ALT and AST were determined and the liver tissue were sampled to observe the expression of TNF-α and IL-1. Results After the ischemia/reperfusion the serum concentration of ALT and AST and expressions of TNF-α and IL-1 in the hepatic tissue in the NS group significantly increased (P<0.01),and the hepatocytic morphologic change was obvious compared with the SO group.
On the 2th day,after polyethylene glycol(PEG)6000 treatment, MDA and H2O2 contents increased more significantly in leaves of Yedan 13 than in Nongda 108,while Nongda 108 showed a more significant increase in contents of Spd,ASA and GSH.
BET results showed that the specific surface area of SO~(2-)_4/SnO_2-Al_2O_3 was larger than SO~(2-)_4/SnO_2.Increasing the calcination temperature the specific surface area of the sample was increased before 500℃ and then decreased.
Manzamine A and sarcophine increased the BP-DNA adducts by 2 to 4-folds.
Increased inhibitory effect of methanol extracts over berberine demonstrates the occurrence of other cytotoxic principles along with main active principle berberine or other factors enhancing the cytotoxic effect of berberine.
The increased glucose flux through this metabolic pathway has been linked to the development of diabetic complications such as neuropathy, nephropathy, retinopathy, and cataract.
Serum VEGF levels increased with diabetic nephropathy stage.
In diabetes, increased flux through the polyol pathway has been implicated in the development of diabetic complications such as cataract, retinopathy, neuropathy, and nephropathy.