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inhibiting
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  抑制
     Mechanism of Matrine Involved in Inhibiting Proliferation and Inducing Differentiation in K-562 Cells
     苦参碱对K562细胞增殖抑制与诱导分化作用的机制研究
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     The Experiment Study on Chlorophyllin Preventing Colorectal Tumors Induced by DMH in Mice and Inhibiting HT29 Cells in Vitro
     叶绿酸铜钠预防化学诱导大肠肿瘤的实验研究及对HT29肠癌细胞的体外抑制作用研究
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     Mechanisms of Cyclosporine A and Tacrolimus Inhibiting the Expression of Costimulatory Molecule 4-1BB in Alloimmune Response after Heart Transplantation in Mice
     环孢霉素A和他克莫司抑制小鼠心脏移植免疫反应中4-1BB分子的表达及其机制研究
短句来源
     The Relation between the Invasion and Metastasis of Esophageal Squamous Cell Carcinoma and Heparanase, the Experimental Study on Inhibiting the Expression of Heparanase in Vivo and in Vitro
     乙酰肝素酶与食管鳞癌浸润转移的关系及体内外抑制乙酰肝素酶蛋白、基因表达的实验研究
短句来源
     Study on Inhibiting Expression of c-Met in Breast Cancer Cells by RNA Interference
     利用RNA干扰抑制乳腺癌细胞c-Met表达的研究
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  缓蚀
     Progress in Research on CO_2/H_2S Corrosion and Inhibiting Technology of Corrosion
     CO_2/H_2S共存腐蚀与缓蚀技术研究进展
     Study on Scale and Corrosion Inhibiting of SAS/IPPA/AA
     SAS/IPPA/AA三元共聚物阻垢缓蚀性能研究
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     Experimental result showed that the inhibiting efficiency of3g/L BL in6 0℃ 1 0 0 g/L H2 SO4amounted to above92 % .
     试验表明 ,在 6 0℃ 1 0 0 g/L H2 SO4中使用 3g/L 的 BL,缓蚀率可达92 %以上。
短句来源
     Na_3PO_4+KMnO_4 and Na_2MoO_4+Na_2SiO_3+KMnO_4 possessed some inhibiting effects on AZ91D magnesium alloy while Na_3PO_4+Na_2B_4O_7 appeared to accelerate its corrosion rate in corrosive water. In E.
     复配Na3 PO4+KMnO4及Na2 MoO4+Na2 SiO3 +KMnO4对AZ91D镁合金腐蚀有缓蚀作用 ,而Na3 PO4+Na2 B4O7会加速其腐蚀 .
短句来源
     A compound formula that screened has a good corrosion and scale inhibiting performance, which anticorrosive rate has achieved 98.03 % and antiscale rate has achieved 91.01 %, which contain 30 mg/L of sodium molybdate, 20 mg/L of HEDP, 1.5 mg/L of zinc acetate, 12.5mg/L of HPMA, 10 mg/L of AMPS.
     筛选出的缓蚀阻垢复合配方组成为钼酸钠30 mg/L、HEDP20 mg/L、乙酸锌1.5 mg/L、HPMA12.5 mg/L、AMPS10 mg/L,该复合配方对碳钢缓蚀率为98.03 %,阻垢率达到91.01 %,具有优良的缓蚀阻垢效果。
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  “inhibiting”译为未确定词的双语例句
     Hirudo suppress the expressions of gelatinase A & B Via inhibiting thrombin receptor PAR-1 activation and fibrin deposition in murine lupus nephritis
     明胶酶A、B在MRL/Lpr自发性狼疮小鼠中的表达以及水蛭调控的机理研究
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     Clinical and Experimental Research of Ping-Yi Mixture on Inhibiting Postoperative Metastatic Tumor
     平移合剂抗肿瘤术后转移的临床及实验研究
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     Study of Molecular Mechanism on Compound Prescription of WeiMaiNing Inhibiting Lung Cancer Metastasis
     复方威麦宁抗肺癌转移作用及其分子机制研究
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     Study on Isolation, Identification, Bioactivity and Biosynthesis of Maituolaimycin Inhibiting HIV PR and CVB6
     抗HIV PR,CVB6麦拓莱霉素的分离、鉴定、活性及生物合成研究
短句来源
     Study on the Effects of Inhibiting hTERT Expression and Paclitaxel on Proliferation and Apoptosis in Hut78 Cells
     干预hTERT的表达及紫杉醇对Hut78细胞增殖及凋亡影响的研究
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  inhibiting
Two of the synthesized compounds proved to be effective in inhibiting HIV-1 replication at micromolar concentrations.
      
Our research is focused on identifying synthetically occurring chemotherapeutic substances capable of inhibiting, retarding, or reversing the process of multistage carcinogenesis.
      
The title compounds were evaluated for their efficacy in inhibiting MDA-MB-231 breast cancer cell proliferation.
      
These revealed that the inhibiting cells discharged more quantity of heat than the normal growing cells.
      
and its response to inhibiting transpiration treatment
      
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Soy-bean phosphatides, sodium oleate and rabbit serum are able to revive the contractility of toad heart inhibited by high potassium(0.054 to 0.074 gram of KCl in 100 ml Ringer solution) and by acetylcholine. During the recovery of the mechanical activity of the cardiac muscle in potassium inhibition, there is always an augmentation of its electrical response. Adrenaline stimulates the potassium as well as the acetylcholine inhibited toad hearts. The action of adrenaline differs from that of the...

Soy-bean phosphatides, sodium oleate and rabbit serum are able to revive the contractility of toad heart inhibited by high potassium(0.054 to 0.074 gram of KCl in 100 ml Ringer solution) and by acetylcholine. During the recovery of the mechanical activity of the cardiac muscle in potassium inhibition, there is always an augmentation of its electrical response. Adrenaline stimulates the potassium as well as the acetylcholine inhibited toad hearts. The action of adrenaline differs from that of the lipids in(i) adrenaline produces no A-V block and(ii) adrenaline promotes the contractility and accelerates the rhythm of the heart.

(一)在高鉀抑制的心臟,大豆磷脂與油脂酸鈉和血清有恢復或增強心臟搏動的能力。 (二)磷脂在加強高鉀抑制中的機械反應同時,亦加強心肌的動作電流。 (三)腎上腺素亦有興奮高鉀與乙醯胆鹼抑制心臟的作用。與磷脂所表現有所不同,腎上腺素在高鉀任氏溶液中不出現房室阻滯;在乙醯胆鹼抑制下,則不但興奮心肌的機械反應且增加心搏的頻率。

(1) Sodium salt of reduced codehydrogenase I has been obtained in good yield as a dry powder from codehydrogenase I by reduction with alcohol and alcohol dehydrogenase. This preparation was stable for at least 5 months when kept dry at -15℃. (2) The properties of the particle-bound codehydrogenase I cytochrome reductase system in heart muscle preparation were found to differ considerably from those of the soluble enzyme as obtained by Mahler et al. Among other things, the affinity for cytochrome c of the particle-bound...

(1) Sodium salt of reduced codehydrogenase I has been obtained in good yield as a dry powder from codehydrogenase I by reduction with alcohol and alcohol dehydrogenase. This preparation was stable for at least 5 months when kept dry at -15℃. (2) The properties of the particle-bound codehydrogenase I cytochrome reductase system in heart muscle preparation were found to differ considerably from those of the soluble enzyme as obtained by Mahler et al. Among other things, the affinity for cytochrome c of the particle-bound enzyme is much greater than the soluble enzyme. The Michaelis constant for cytochrome c of the former is only one twelfth of that of the latter.(Fig. 2A). (3) With either oxygen or excess cytochrome c as electron acceptor, it was found that the overall activity, in terms of rate of oxygen consumption or cytochrome c reduction, when both succinate and reduced codehydrogenase I were oxidized simultanously, did not represent the sum of the rates of oxidation when these two substrates were separately oxidized but equalled only the faster of the two separate oxidation rates(Fig. 5, Tables 1, 2). If 2,6-dichlorophenol indophenol was used as the electron acceptor, the overall rate of simultaneous oxidation of these two substrates was found to equal exactly the sum of the rates of separate oxidation(Table 3). (4) When either oxygen or excess cytochrome c was used as the electron acceptor, reduced codehydrogenase I and succinate each inhibited the rate of oxidation of the other(Figs 4, 6 & 7). Evidence has been presented to show that the inhibition of succinate oxidation by reduced codehydrogenase I is not due to the accumulation of oxaloacetate. (5) When malonate was also added to the reaction mixture, succinate no longer produced any inhibition of the oxidation of reduced codehydrogenase I(Fig. 8). (6) It is therefore concluded that in heart muscle preparation both succinate and reduced codehydrogenase I are oxidized by cytochrome c through a common, velocity limiting factor. This is in accordance with the view previously reached by some workers from studies on the action of certain inhibitors. However, it should be noted that in our experiments no agents which might produce any conceivable change in the colloidal structure of the enzyme system has been employed. (7) It should be emphasized that our results clearly show that great caution must be exercised in drawing conslusion on the role an enzyme might play in a complex enzyme system from studies of the properties of a solubilized enzyme. (8) It is believed that the competition of two enzyme systems for a common linking factor as demonstrated in this report has provided a new method for studies on the mutual relations of two or more enzyme systems.

(一)本報告提供了一個從輔酶Ⅰ,用酶還原法製備還原輔酶Ⅰ的方法。我們所製得的還原輔酶Ⅰ鈉鹽乾粉,可以在低温保存數月而不被氧化。 (二)與心肌製劑中顆粒相結合的輔酶Ⅰ細胞色素還原酶系,和用乙醇抽出的水溶性的輔酶Ⅰ細胞色素還原酶的性質頗不相同。其中比較重要的不同點是對於細胞色素c的親力,前者遠大於後者,其米氏常數僅約為後者的十二分之一。 (三)用一心肌顆粒製劑作為材料,無論用氧或過量之細胞色素c作為氫受體,還原輔酶Ⅰ與琥珀酸同時氧化時的總速度,不等於二者分別氧化時速度之和,而僅等於其中氧化較快者單獨氧化時之速度。但如用[2,6]二氯靛酚作為氫受體時,二者共同氧化時之總速度完全等於二者分別氧化時速度的和。 (四)當用氧或過量之細胞色素c作為氫受體時,琥珀酸與還原輔酶Ⅰ能彼此互相抑制對方氧化的速度。有足夠的實驗材料說明,還原輔酶Ⅰ對於琥珀酸氧化的抑制,不是由於草醯乙酸聚集的緣故。 (五)如果在反應混合物中同時含有琥珀酸脫氫酶的專一抑制劑,丙二酸,則琥珀酸對於還原輔酶Ⅰ氧化作用的抑制即被解除。 (六)根據以上的實驗結果,可以認為,還原輔酶Ⅰ及琥珀酸先通過一個共同的因子與細胞色素c作用。這個共同的因子在一般情形之下,也是...

(一)本報告提供了一個從輔酶Ⅰ,用酶還原法製備還原輔酶Ⅰ的方法。我們所製得的還原輔酶Ⅰ鈉鹽乾粉,可以在低温保存數月而不被氧化。 (二)與心肌製劑中顆粒相結合的輔酶Ⅰ細胞色素還原酶系,和用乙醇抽出的水溶性的輔酶Ⅰ細胞色素還原酶的性質頗不相同。其中比較重要的不同點是對於細胞色素c的親力,前者遠大於後者,其米氏常數僅約為後者的十二分之一。 (三)用一心肌顆粒製劑作為材料,無論用氧或過量之細胞色素c作為氫受體,還原輔酶Ⅰ與琥珀酸同時氧化時的總速度,不等於二者分別氧化時速度之和,而僅等於其中氧化較快者單獨氧化時之速度。但如用[2,6]二氯靛酚作為氫受體時,二者共同氧化時之總速度完全等於二者分別氧化時速度的和。 (四)當用氧或過量之細胞色素c作為氫受體時,琥珀酸與還原輔酶Ⅰ能彼此互相抑制對方氧化的速度。有足夠的實驗材料說明,還原輔酶Ⅰ對於琥珀酸氧化的抑制,不是由於草醯乙酸聚集的緣故。 (五)如果在反應混合物中同時含有琥珀酸脫氫酶的專一抑制劑,丙二酸,則琥珀酸對於還原輔酶Ⅰ氧化作用的抑制即被解除。 (六)根據以上的實驗結果,可以認為,還原輔酶Ⅰ及琥珀酸先通過一個共同的因子與細胞色素c作用。這個共同的因子在一般情形之下,也是這兩個酶系統的速度限制因子。應該指出在我們的實驗中,並未使用任何可能影響酶系統結構的條件,因此我們的結果是在一個比較接近於生理狀態的情形之下獲得的。 (七)應該着重指出,從本報告的結果可以看到,一個用人為的方法從複雜酶系上溶解下來的酶的性質,有時並不能代表這個酶在有組織的酶系統中的真實情况。 (八)我們相信,本報告所說明的兩酶系競爭一個共同因子的一些現象,將为研究複雜酶系之間的相互關係,提供一個新的方法。

In chronical experiments on dogs provided with gastric pouches, we showed that the gastric secretion stimulated by histamine can be reflexly inhibited by electrical stimulation on the skin. This inhibition can be shown with Heidenhain pouches as well as with Pavlov pouches, indicating that the phenomenon does not depend on an intact vagus innervation. Furthermore it can still appear in Heidenhain pouches after bilateral subdiaphragmatic section of the splanchnic nerves and bilateral extirpation of the...

In chronical experiments on dogs provided with gastric pouches, we showed that the gastric secretion stimulated by histamine can be reflexly inhibited by electrical stimulation on the skin. This inhibition can be shown with Heidenhain pouches as well as with Pavlov pouches, indicating that the phenomenon does not depend on an intact vagus innervation. Furthermore it can still appear in Heidenhain pouches after bilateral subdiaphragmatic section of the splanchnic nerves and bilateral extirpation of the solar plexuses. In such dogs the adrenal glands are of course also severed from their external nerve supplies. It thus follows that the sympathetic innervation to the stomach and the adrenal glands are not indispensable either. Apparently there is some humoral factor as yet unknown, which inhibits gastric secretion and which can be reflexly mobilized by such means as electrical stimulation of the skin. On the other hand, we were able to show that both direct electrical stimulation of the splanchnic nerve and intravenous injection of adrenaline can inhibit the gastric secretion stimulated by histamine. This suggests that when the sympathetico-adrenal system is intact it is likely to be also involved in the inhibitory phenomenon under consideration. The phenomenon is evidently a complex one involving both nervous and humoral factors, and we had also shown that it requires the participation of higher nervous centres, being not elicitable in anesthetized animals. We wish to express our deep gratitude to Prof. T. P. Feng for suggesting this problem and for constant guidance throughout this work.

(一)在慢性實驗中用備有小胃的狗,我們证明組織胺引起的胃分泌能反射地为皮膚電刺激及一些其他外界刺激所抑制。 (二)這抑制現象在除去胃的迷走神經支配相交或神經支配,並隔離腎上腺的神經聯系時,仍能出現。它似有某種可以反射地形成的抑制性體液變化為基礎。 (三)但在急性實驗中我們又證明大內臟神經和注射腎上腺素均能抑制組織胺引起的胃分泌,這指示在正常動物胃分泌的反射抑制仍可能通過交感神經-腎上腺系統而得實現。 (四)本文所述的胃分泌的反射抑制現象顯然包含複雜的神經-體液機制,並且是在高級神經中樞參加下產生的。

 
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