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tumors     
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  肿瘤
     Integrin Expression and Its Clinic Values in Urologic Tumors
     整合素在泌尿系肿瘤中的表达及其临床意义的初步研究
短句来源
     Dynamic Susceptibility Contrast MR Perfusion Imaging of Brain Tumors
     脑肿瘤动态增强磁化率MR灌注成像的研究
短句来源
     Genetic Aberrations of WHO Type A, B3 and C Thymic Epithelial Tumors and Their Pathogenesis
     WHO-A、B3和C型胸腺上皮性肿瘤遗传变异及其发病机理的研究
短句来源
     Clinical Study of Multi-Voxel Proton MR Spectroscopy in Brain Tumors
     脑肿瘤多体素磁共振质子波谱临床研究
短句来源
     Study on Molecular Diagnostic Markers in Follicular Tumors and Tumor-like Lesions of Thyroid
     甲状腺滤泡细胞源性肿瘤及瘤样病变分子诊断标志物的研究
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  肿瘤的
     The Experiment Study on Chlorophyllin Preventing Colorectal Tumors Induced by DMH in Mice and Inhibiting HT29 Cells in Vitro
     叶绿酸铜钠预防化学诱导大肠肿瘤的实验研究及对HT29肠癌细胞的体外抑制作用研究
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     Liposomes as Drug Carriers Targeting to Lymphatic Metastatic Tumors
     脂质体作为靶向淋巴转移性肿瘤的药物载体研究
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     Study of MR Imaging of Female Genital System Tumors
     女性生殖系统肿瘤的MRI研究
短句来源
     Diagnostic Value of CT Perfusion and MR Diffusion-weighted Imaging in Adrenal Tumors and Correlation with Pathology: A Preliminary Study
     CT灌注成像和MR弥散加权成像对肾上腺肿瘤的诊断价值及其与病理表现对照的初步研究
短句来源
     The Experimental Study and Clinical Research of Local Chemotherapy of Sacrum Tumors after Operation
     肿瘤局部切、刮术、残腔置管灌注化疗治疗骶骨肿瘤的实验研究及临床应用
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     Regulation of Somatostatin Receptor on Small Cell Lung Cancer Cells and Imaging of Radiolabeled RC-160 in Mice Bearing Tumors
     小细胞肺癌的生长抑素受体调变及核素标记RC-160的荷小鼠显像研究
短句来源
     Study on Molecular Diagnostic Markers in Follicular Tumors and Tumor-like Lesions of Thyroid
     甲状腺滤泡细胞源性肿样病变分子诊断标志物的研究
短句来源
     Brenner Tumors of the OVary with Report of Five Cases
     卵巢勃利奈氏(附五例报告)
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     SALIVARY GLAND TUMORS AND TUMOR-LIKE LESIONS ( ANALYSIS OF 415 CASES)
     唾腺肿样病变——415例分析
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     Glomus Tumors of the Extremities. Report of 12 Cases
     四肢血管球(附12例报告)
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  肿瘤组织
     (2) The positive rate of MUC2 expression in 41 primary ovarian tumors (benign,borderline,malignant) was 8.3% (1/12),5/9,80% (16/12) respectively,and the positive rate of MUC5AC in those carcinomas was 100% (12/12),9/9,90% (18/20).
     (2)MUC2在良性、交界性、恶性原发性卵巢黏液性肿瘤组织中的阳性表达率分别为8·3%(1/12)、5/9、80·0%(16/20),MUC5AC阳性表达率分别为100·0%(12/12)、9/9、90·0%(18/20);
短句来源
     The mean estimated radiation doses in tumors were (130.34±54.53)Gy, (34.73±13.41)Gy in normal liver tissue, and ranged from 2.1 to 16.3 Gy in lung tissue.
     估算肿瘤组织的平均吸收剂量(130.34±54.53)Gy,非瘤肝组织为(34.73±13.41)Gy,肺组织2.1~16.3Gy。
短句来源
     The Expression and Clinicopathologic Significance of HEP,AFP,CK19 and CD10 in Hepatic Tumors
     肝脏肿瘤组织中HEP、AFP、CK19及CD10的表达及意义
短句来源
     (2)Significant differences between tumors of high-grade gliomas and solitary metastasis were found in the ratios of NAA/Cr and NAA/Cho(P<0.01),but no significant differences were found in the ratios of Cho/Cr(P>0.05);
     (2)高级别脑胶质瘤和孤立脑转移瘤的肿瘤组织的NAA/Cr和NAA/Cho比值存在显著性差异(P<0.01),但Cho/Cr比值无显著性差异(P>0.05);
短句来源
     The expression of C-erbB_2、 P_(16)gene in ovarian tumors and the relationship between its and pronosis
     卵巢肿瘤组织中C-erbB_2、P_(16)基因的表达及与预后的关系
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      tumors
    EGFR is over-expressed in numerous tumors including, those derived from the brain, lung, bladder, head and neck.
          
    Design and analysis of small-molecule antineoplastic agents targeting brain tumors by utilizing pattern recognition methods and
          
    This paper is devoted to studying a free boundary problem modeling the effects of drug resistance and vasculature on the response of solid tumors to therapy.
          
    Successful immunotherapy of tumors requires understanding of the natural relationship between the immune system and tumor in the status of differentiation, invasion and maturation.
          
    The detection of tumor markers is extensively used for the diagnosis of corresponding tumors.
          
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    The willow worm, Actias selene Hubner, belongs to the Saturinudae. The worms live outdoor on trees—most frequently on willows. However, they are perfectly fit to indoor conditions. On account of their strong vitality, the breeding of the worms presents almost no difficulty. Our preliminary breeding of the worms shows that under ordinary conditions and feeding with willow leaves they grow very well. In a better case it only takes 24 days from their larvas to cocoon. They breed three generations in one year, and...

    The willow worm, Actias selene Hubner, belongs to the Saturinudae. The worms live outdoor on trees—most frequently on willows. However, they are perfectly fit to indoor conditions. On account of their strong vitality, the breeding of the worms presents almost no difficulty. Our preliminary breeding of the worms shows that under ordinary conditions and feeding with willow leaves they grow very well. In a better case it only takes 24 days from their larvas to cocoon. They breed three generations in one year, and their pupas survive in winter. Willow worms are heavier than ordinary domestic silkworms. A well-developed willow worm weighs over 10 grams and is 7-8 cm. in length. With a green colour, its body is scattered with tumors and full of hairs on their tips. The silk of willow worms presents a light-coffee colour and a shining lustre. As compared with that of domestic worms, it is somewhat thicker, while their tensile strength and elongation are nearly similar. Out of one cocoon a silk thread of about 350 meters in length may be obstained. It has the potentiality of being developed into a textile raw-material.

    这篇报告是介绍一种野生蚕——柳蚕和柳蚕丝初步试验的情况。柳蚕在上海一带常见,许多地区也有分布。我们为了探求对它的利用,曾把它移放在室内饲养,发现生长良好,饲养方便。从蟻蚕到结茧,快的24天,就能结茧。一年中一般有三个世代,以蛹越冬。蚕身为绿色,体重比家蚕大,成熟的蚕儿有10克多重,身长达7~8公分。身上有瘤状突起,突起顶端长有刚毛。吐丝呈浅咖啡色,具有光泽,强力和延伸与家蚕丝相仿,但比家蚕丝略粗。柳蚕的特点是:生活力强;吃柳树叶(湿叶也无影响);虽系野生,但能在室内饲养;茧子又可以繅出成缕的丝达350公尺,是天然丝的一种资源。因此它可能具有重大的国民经济意义。

    An experimental study of 300 mice exposed to pitch(3 gm.dissolved in 10 ml.of 80% benzene solution)obtained from 4 different sources,name- ly Anshan coal-tar pitch,Yu-men petroleum pitch,Dairen petroleum pitch or commonly known as Russian crude oil and the Asia Oil Company, USA,was carried out over a period of 350 days. From the beginning a group of these experimen- tal animals was exposed to artificial sun-ray for 2 hours a day.The results of our experiment indicate that pathological changes of different degrees...

    An experimental study of 300 mice exposed to pitch(3 gm.dissolved in 10 ml.of 80% benzene solution)obtained from 4 different sources,name- ly Anshan coal-tar pitch,Yu-men petroleum pitch,Dairen petroleum pitch or commonly known as Russian crude oil and the Asia Oil Company, USA,was carried out over a period of 350 days. From the beginning a group of these experimen- tal animals was exposed to artificial sun-ray for 2 hours a day.The results of our experiment indicate that pathological changes of different degrees of severity,such as chronic dermatitis and tumor formation,were the commonest effect of pitch on skin both in the exposed and non-ex- posed groups while the control group(exposed to 80% benzene only)showed only slightly acute dermatitis. The pathological changes as observed both in gross appearances and histological findings are given in detail. The course of tumor formation as found in both the exposed and the non-exposed groups may be classified in the order of time sequence as benign squamous papilloma,malignant squamous papilloma and finally squamous-celled carcinoma; also a few cases of sarcoma and a few cases of so- called“Myoblastoma”. Through the action of photosensitivity to the exposed group,the prolongation of the latent period of tumor formation,the effectiveness in the development of dermatitis and malignant changes in tumors were clearly observed in the process of the pathological changes. The relative potency of the carcinogenic pitch obtained from the above sources has been calculated by means of the statistical analysis of both the incidence and the length of time for the development of the cutaneous tumors.

    (一)四种来源不同的沥青(鞍山煤焦油沥青、西北玉门石油沥青、大连石油沥青、和美国亚细亚公司石油沥青)经涂抹小白鼠的实验证明具有引起皮肤各种的病理变化的作用。其中包括慢性渗出性皮炎;慢性炎性上皮结缔组织增生;良性皮肤乳头状瘤;皮肤鳞状细胞癌。此外也引起了少数的肉瘤和“肌母细胞痛”。皮肤瘤发生的潜伏期由62天至406天不等。(二)光感作用可以加剧及加速煤焦油沥青皮肤炎的进展,和发炎皮肤的角化现象。至于对沥青致癌作用本实验未能证实其有显著的影响。(三)根据四种来源不同的沥青所引起皮肤良性与恶性病变的发病率和潜伏期的长短,可将其毒性的强弱顺序排列如下:(1)鞍山煤焦油沥青,(2)美国亚细亚公司石油沥青,(3)大连石油沥青(苏联原油),(4)西北玉门石油沥青。即煤焦油沥青毒性远较石油沥青为强。国产石油沥青的毒性较外产石油沥青的毒性为弱。

    AT-290, p-bis (2-chloroethyl) aminomethyl phenylalanine, synthesized at our Institutc, is a new derivative of nitrogen mustard. Animal experiments showed that AT-290 had a significant antitumor activity. The results on toxicity and antitumor activity were as follows: 1. The acute and subacute intraperitoneal LD_(50) for mice were 4 and 1.6 mg/kg/day respectively. The subacute oral LD_(50) in mice was 11 mg/kg/day and the subacute intraperitoneal LD_(50) in rats was 1 mg/kg/day. 2. In 3 dogs, intravenous injections...

    AT-290, p-bis (2-chloroethyl) aminomethyl phenylalanine, synthesized at our Institutc, is a new derivative of nitrogen mustard. Animal experiments showed that AT-290 had a significant antitumor activity. The results on toxicity and antitumor activity were as follows: 1. The acute and subacute intraperitoneal LD_(50) for mice were 4 and 1.6 mg/kg/day respectively. The subacute oral LD_(50) in mice was 11 mg/kg/day and the subacute intraperitoneal LD_(50) in rats was 1 mg/kg/day. 2. In 3 dogs, intravenous injections of 75 γ/kg/day of AT-290 for 10 days produced no remarkable influence on the general behavior, erythrocyte, leukocyte and platelet counts, bleeding and coagulation time, urinalysis and EKG, but caused a significant lymphocytopenia in the peripheral blood. In another 6 dogs, AT-290 at the dosages of 150 and 300 γ/kg exhibited an inhibiting effect upon the bone marrow, as evidenced by a peripheral leukopenia and thrombopenia, delayed bleeding time, and hematopoitic depression in the bone marrow. The animals treated with 75 and 150 γ/kg gradually recovered after cessation of the drug, while those given 300 γ/kg died in 13—19 days. 3. AT-290 inhibited significantly the growth rate of Jensen sarcoma and fibrosarcoma M-57 in rats. Experiments on 3 ascites tumors of mice (Ehrlich ascites carcinoma, spindle cell sarcoma and mammary adenocarcinoma) showed that AT-290 significantly prolonged the survival time of the tumor-bearing mice.

    本文介绍新的氮芥衍生物 AT-290 卽对-双(β-氯乙基)氨甲基苯丙氨酸二盐酸盐的毒性试验及实验治疗的结果。 1.本药在小鼠腹腔注射的急性LD_(50)为4毫克/公斤,亚急性口服和腹腔注射的LD_(50)分别为11及1.6毫克/公斤,大鼠腹腔注射的亚急性LD_(50)为1毫克/公斤。 2.狗毒性试验证明,AT-290 在75微克/公斤静脉注射每天1次连续10天,对狗的一般状态、体重、红、白血球数、血小板数、出血时间、凝血时间、尿及心电图检查均无明显影响;但却对淋巴细胞表现出明显抑制作用。150及300微克/公斤时,可抑制动物的骨髓机能,主要表现为白血球总数及血小板减少、出血时间延长、骨髓中幼稚细胞消失,对淋巴球的作用与75微克/公斤组同。这些情况在150微克/公斤组停药后一定时间自行恢复,而大剂量组(300微克/公斤)则动物死亡。 3.本药腹腔注射时对三种小白鼠腹水型肿瘤(Ehrlich腹水癌、梭形细胞肉瘤腹水型及腹水型乳腺癌)均有明显抑制作用,可延长动物的生存时间至2倍以上,对小白鼠实体型肿瘤(淋巴白血病L-2、Ehrlich癌、Crocker肉瘤及梭形细胞肉瘤) 均无明显抑制作用。对大白鼠Jensen肉...

    本文介绍新的氮芥衍生物 AT-290 卽对-双(β-氯乙基)氨甲基苯丙氨酸二盐酸盐的毒性试验及实验治疗的结果。 1.本药在小鼠腹腔注射的急性LD_(50)为4毫克/公斤,亚急性口服和腹腔注射的LD_(50)分别为11及1.6毫克/公斤,大鼠腹腔注射的亚急性LD_(50)为1毫克/公斤。 2.狗毒性试验证明,AT-290 在75微克/公斤静脉注射每天1次连续10天,对狗的一般状态、体重、红、白血球数、血小板数、出血时间、凝血时间、尿及心电图检查均无明显影响;但却对淋巴细胞表现出明显抑制作用。150及300微克/公斤时,可抑制动物的骨髓机能,主要表现为白血球总数及血小板减少、出血时间延长、骨髓中幼稚细胞消失,对淋巴球的作用与75微克/公斤组同。这些情况在150微克/公斤组停药后一定时间自行恢复,而大剂量组(300微克/公斤)则动物死亡。 3.本药腹腔注射时对三种小白鼠腹水型肿瘤(Ehrlich腹水癌、梭形细胞肉瘤腹水型及腹水型乳腺癌)均有明显抑制作用,可延长动物的生存时间至2倍以上,对小白鼠实体型肿瘤(淋巴白血病L-2、Ehrlich癌、Crocker肉瘤及梭形细胞肉瘤) 均无明显抑制作用。对大白鼠Jensen肉瘤及纤维肉瘤M-57疗效则很显著。

     
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