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massive hemorrhage during surgery
相关语句
  术中大出血
     Clinical studies of anesthetic management and fluid therapy for patients with massive hemorrhage during surgery
     术中大出血病人的麻醉处理与容量治疗的临床研究
短句来源
  “massive hemorrhage during surgery”译为未确定词的双语例句
     Effects of hypertonic saline on proinflammatory cytokine in patients following acute massive hemorrhage during surgery
     高渗盐水对手术中急性大出血患者血清促炎性细胞因子的影响
短句来源
     Objective To explore the effects of hypertonic saline (HS) on proinflammatory cytokine in patients following acute massive hemorrhage during surgery.
     目的 探讨 7 5 %的高渗盐水 (HS)对手术中急性大出血患者血清促炎性细胞因子的影响。
短句来源
  相似匹配句对
     The value of embolization in acute massive hemorrhage
     急诊栓塞在抢救急性大出血患者中的临床应用
短句来源
     Treatment of massive hemorrhage during hepatectomy
     肝叶切除手术出血的处理
短句来源
     Two cases died of massive hemorrhage.
     放疗后支架置入并发症增加 ,大出血致死 2例。
短句来源
     Surgery therapy of acute upper gastrointestinal massive hemorrhage
     急性胃十二指肠大出血外科治疗
短句来源
     Nursing experience in massive hemorrhage following hemorrhoids surgery
     痔疮术后大出血护理体会
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Objective To investigate physiological changes, anesthetic management and effect of fluid therapy on restoring blood volume in patients with massive hemorrhage during surgery Methods We retrospectively studied 538 adult patients with blood loss more than 40% of total blood volume during surgery General anesthesia(476 cases)and epidural anesthesia (62 cases) were performed BP ECG、SPO2、CVP、HCT、Urinaryvolume and blood gas analyse were monitored When massive hemorrhage occurred,...

Objective To investigate physiological changes, anesthetic management and effect of fluid therapy on restoring blood volume in patients with massive hemorrhage during surgery Methods We retrospectively studied 538 adult patients with blood loss more than 40% of total blood volume during surgery General anesthesia(476 cases)and epidural anesthesia (62 cases) were performed BP ECG、SPO2、CVP、HCT、Urinaryvolume and blood gas analyse were monitored When massive hemorrhage occurred, blood volume was maintained by mainly infusing Gelofusine or hydroxyethyl starch, sodium lactate Ringer's solution and properly transfusing packed red blood cells or whole blood Results Average blood loss was(2552±1025)ml Sixty one patients and thirteen patients presented hypotension and shock respectively A hundred and six patients presented with low CVP The values of HCT,PH,BE and serum potassium after massive hemorrhage were lower than before surgery (P<0 01 or P<0 05) in58 patients whose blood loss were beyond 3000ml Conclusions General anesthesia is most appropriate for the patients with tendency of massive hemorrhage duting surgery Fluid and transfusion therapy can restore blood volume effectively in most patients, bust can not in few patients due to incontrollable bleeding and insufficient blood supply

目的 探讨术中大出血病人的生理改变、麻醉估计与术中管理及以人造血浆代用品为主的容量治疗效果。方法 对术中出血量占全身血容量 40 %以上各种大手术病人 5 38例。采用气管内插管全麻 476例 ,硬膜外阻滞 6 2例 (术中大出血后改全麻 2 7例 ) ;术中监测血压、心电图、脉搏氧饱和度 (Sp O2 )、尿量 ,大部分病人监测中心静脉压 (CVP)、红细胞压积 (Hct)、血气分析。术中大出血时以血定安或羟乙基淀粉、乳酸钠林格氏液为主静脉输入 ,适量输红细胞或全血。结果  5 38例病人出血量为 (2 5 5 2± 10 2 5 ) m l,出现低血压 6 1例 (11.3% ) ,休克 13例 (2 .4% ) ,CVP<4mm H2 O者 10 6例 (19.7% ) ,Sp O2 <92 %者 32例 (5 .9% )。出血量 30 0 0 m l以上的病人的 Hct、 PH、 HCO3、 BE、 K+均显著降低 (P <0 .0 5或 P <0 .0 1)。结论 对估计术中出血量大或以可能意外损伤大血管引起大出血病人最好选择气管内全身麻醉 ,加强监测。术中大量出血时 ,采取以输液输血为主的容量治疗...

目的 探讨术中大出血病人的生理改变、麻醉估计与术中管理及以人造血浆代用品为主的容量治疗效果。方法 对术中出血量占全身血容量 40 %以上各种大手术病人 5 38例。采用气管内插管全麻 476例 ,硬膜外阻滞 6 2例 (术中大出血后改全麻 2 7例 ) ;术中监测血压、心电图、脉搏氧饱和度 (Sp O2 )、尿量 ,大部分病人监测中心静脉压 (CVP)、红细胞压积 (Hct)、血气分析。术中大出血时以血定安或羟乙基淀粉、乳酸钠林格氏液为主静脉输入 ,适量输红细胞或全血。结果  5 38例病人出血量为 (2 5 5 2± 10 2 5 ) m l,出现低血压 6 1例 (11.3% ) ,休克 13例 (2 .4% ) ,CVP<4mm H2 O者 10 6例 (19.7% ) ,Sp O2 <92 %者 32例 (5 .9% )。出血量 30 0 0 m l以上的病人的 Hct、 PH、 HCO3、 BE、 K+均显著降低 (P <0 .0 5或 P <0 .0 1)。结论 对估计术中出血量大或以可能意外损伤大血管引起大出血病人最好选择气管内全身麻醉 ,加强监测。术中大量出血时 ,采取以输液输血为主的容量治疗可有效的恢复血容量。当大量出血无法控制或血源不足时 ,单纯输入液体不能凑效。

Objective To explore the effects of hypertonic saline (HS) on proinflammatory cytokine in patients following acute massive hemorrhage during surgery.Methods Thirty_eight adult patients with acute massive hemorrhage(over 10 ml/(kg·30min)) during operation were randomly divided into two groups: hypersonic saline group (HS group n=20),and Lactate Ringer's group(LR group,n=18).Patients in HS group received intravenous 7.5% HS 4 ml/kg within 5 min immediately when they had been bleeding...

Objective To explore the effects of hypertonic saline (HS) on proinflammatory cytokine in patients following acute massive hemorrhage during surgery.Methods Thirty_eight adult patients with acute massive hemorrhage(over 10 ml/(kg·30min)) during operation were randomly divided into two groups: hypersonic saline group (HS group n=20),and Lactate Ringer's group(LR group,n=18).Patients in HS group received intravenous 7.5% HS 4 ml/kg within 5 min immediately when they had been bleeding over 10 ml/(kg·30 min).Patients in LR group was resuscitated with equal mounts of LR and via the same methods. During operation other fluid replacement or blood was used to increase patients blood volume.Tumor necrosis factor-a (TNF-α),interleukin-6 (IL-6), interleukin-8 (IL-3)were separately measured 5 min before anesthesia (T 1), the moment before infusing HS or LR (T 2), 1 h after infusing HS or LR(T 3), at the end of operation (T 4) and 24 h after surgery (T 5) in two groups.Results The serum levels of TNF-a, IL-6 and IL-8 in two groups were obviously increased at T 2~ T 5 (P<0.05 or 0.01). But compared with LR group, the levels of TNF-α, IL-6 and IL-8 in HS group were significantly decreased at T 2~T 5 (P<0.05).HS could also rapidly raise patients' blood pressure. Conclusion In resuscitating trauma and acute massive hemorrhage during operation, 7.5% HS can inhibit the production and release of proinflammatory TNF-α, IL-6 and IL-8, and prevent systemic inflammatory response.

目的 探讨 7 5 %的高渗盐水 (HS)对手术中急性大出血患者血清促炎性细胞因子的影响。方法  38例术中急性大出血 [出血量 >10ml/ (kg·h) ]的成年患者 ,随机分为两组 :高渗盐水组 (HS组 ,n =2 0 )和乳酸钠林格液组 (LR组 ,n =18)。HS组于术中急性出血量达 10mg/kg体重时静脉输注 7 5 %的HS ,按 4ml/kg体重的剂量 5min内输完 ,LR组用同种方法输注等容量的LR。同时 ,整个手术期间根据患者的血流动力学参数输注其它的血浆代用品或全血 ,以纠正低血容量。详细记录输HS/LR前后液体的出入量。并分别于手术前 5min (T1 )、HS或LR输注前即刻 (T2 )、HS或LR输注后 1h (T3)、术毕 (T4 )和术后 2 4h (T5)各时点测定血清中肿瘤坏死因子 a (TNF α)、白细胞介素 6 (1L 6 )和白细胞介素 8(IL 8)。结果 与术前基础值 (T1 )比较 ,两组T2 ~T5血清TNF α、IL 6和IL 8的浓度均明显升高 (P <0 0 5或0 0 1) ,但HS组T3~T5血清TNF α、IL 6和IL 8的浓度...

目的 探讨 7 5 %的高渗盐水 (HS)对手术中急性大出血患者血清促炎性细胞因子的影响。方法  38例术中急性大出血 [出血量 >10ml/ (kg·h) ]的成年患者 ,随机分为两组 :高渗盐水组 (HS组 ,n =2 0 )和乳酸钠林格液组 (LR组 ,n =18)。HS组于术中急性出血量达 10mg/kg体重时静脉输注 7 5 %的HS ,按 4ml/kg体重的剂量 5min内输完 ,LR组用同种方法输注等容量的LR。同时 ,整个手术期间根据患者的血流动力学参数输注其它的血浆代用品或全血 ,以纠正低血容量。详细记录输HS/LR前后液体的出入量。并分别于手术前 5min (T1 )、HS或LR输注前即刻 (T2 )、HS或LR输注后 1h (T3)、术毕 (T4 )和术后 2 4h (T5)各时点测定血清中肿瘤坏死因子 a (TNF α)、白细胞介素 6 (1L 6 )和白细胞介素 8(IL 8)。结果 与术前基础值 (T1 )比较 ,两组T2 ~T5血清TNF α、IL 6和IL 8的浓度均明显升高 (P <0 0 5或0 0 1) ,但HS组T3~T5血清TNF α、IL 6和IL 8的浓度均显著低于LR组 (P <0 0 5 )。同时 ,HS纠正低血压状态更迅速有效。结论  7 5 %的HS可以有效抑制手术中急性大出血时促炎性细胞因子的合成和释放 ,预防全身炎症反应的发生

 
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