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tumor necrosis factor
相关语句
  肿瘤坏死因子-
     TUMOR NECROSIS FACTORα IN EXPERIMENTAL PROLIFERATIVE VITREORETINOPATHY INDUCED BY MACROPHAGES
     巨噬细胞诱发的实验性增殖性玻璃体视网膜病变中玻璃体内的肿瘤坏死因子-α
短句来源
  “tumor necrosis factor ”译为未确定词的双语例句
     Methods Tumor necrosis factorα (TNFα),interlukin1β(IL1β)secreted by peripheral blood mononuclear cells(PBMC) and TNFα,soluble interlukin2 receptor(sIL2R) in serum form 60 epileptic children(23 with PB,13 with CBE,24 without medication)and 20 controls were studied.
     方法用ELISA和RIA测定60例癫痫患儿(其中23例服用PB,13例服用CBZ,24例未服药)及20例对照者的外周血单个核细胞分泌的TNFα、IL1β及血清TNFα、sIL-2R。
短句来源
     The level of T lymphocyte subsets in peripheral blood and tumor necrosis factorα in serum of 68 cases with viral myocarditis(VMC) were monitored.
     观察了68例小儿病毒性心肌炎外周血T淋巴细胞亚群和血清肿瘤坏死因子α(sTNFα)的变化。
短句来源
     おt is still a matter in dispute whether the bioactivity of membraneassociated form of tumor necrosis factorα(mTNFα) is TNF receptor (TNFR)dependent.
     用可溶性TNFR预先与mTNFα或sTNFα温育可明显抑制两型TNF随后的胞毒效应;
短句来源
     This suggests that DNAantiDNA ICs may be valuable in the evaluation of disease activity and treatment of LN. The activity of LN was also found to be significantly correlated with soluble interleukin2 receptor (sIL2R), tumor necrosis factorα(TNFα),IL6 and endothelin(ET). We first reported that macrophage migration inhibitory factor (MIF) is associated with renal injury and activity of SLE.
     在细胞因子与LN的相关性研究中,发现可溶性白介素2受体(sIL2R)、肿瘤坏死因子α(TNFα)、IL6及内皮素(ET)等与SLE的活动性明显相关,而且在国内外首次发现巨噬细胞移动抑制因子(MIF)与SLE活动性及肾损害密切相关。
短句来源
     Objective: In investigate the effects of local injection of recombinant human tumor necrosis factorα(rhTNFα) on heterotopic bone formation (HBF) induced by bovine bone morphogenetic protein (bBMP) in the muscle porch of mice.
     目的:了解局部注射重组人α肿瘤坏死因子(rhTNF-α)对牛骨形态发生蛋白(bBMP)在小鼠体内异位诱导成骨的影响。
短句来源
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  相似匹配句对
     ③Tumor incompletely necrosis.
     ③肿瘤不完全坏死。
短句来源
     ④Tumor necrosis and ulceration;
     ④肿瘤坏死和溃疡;
短句来源
     RESEARCH ADVANCES OF TUMOR NECROSIS FACTOR
     肿瘤坏死因子研究进展
短句来源
     Tumor Necrosis Factor-alpha and Psoriasis
     肿瘤坏死因子α与银屑病
短句来源
     Tumor necrosis factor and diabetic retinopathy
     TNF与糖尿病视网膜病变
短句来源
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TNF (tumor necrosis factors) was obtained from the serum of Japanese Polish Rabbit which was sensitized with Propionibacterium acnes and injected with LPS(lipopolysaccharide). The morphological changes of the cultured rat glioma cells (GAI, C-6) and human glioma cells (marcus) were observed after using TNF. It showed granules appeared in cytoplasma and became most evident on the 3rd day. This study represented the possibility of treatment of human brain glioma with TNF, although it is necessary to further...

TNF (tumor necrosis factors) was obtained from the serum of Japanese Polish Rabbit which was sensitized with Propionibacterium acnes and injected with LPS(lipopolysaccharide). The morphological changes of the cultured rat glioma cells (GAI, C-6) and human glioma cells (marcus) were observed after using TNF. It showed granules appeared in cytoplasma and became most evident on the 3rd day. This study represented the possibility of treatment of human brain glioma with TNF, although it is necessary to further study the effect of TNF on the glioma.

作者研究了由兔产生的肿瘤坏死因子(TNF)对鼠源性脑胶质瘤细胞GAI、C-6和人脑胶质瘤细胞marcus的作用,发现TNF对上述三种细胞都显示了明显的细胞毒作用,肿瘤细胞崩解死亡。本实验提示了将来TNF作为治疗恶性脑胶质瘤的一种新方法的可能性。

Using light microscope and electron microscope,we observed the morphological changes in the SMMC-7721 human hepatocellular carcinoma cell line after it was exposed to the rabbit tumor necrosis factor (TNF)and the cytocidal effect of TNF on the heterotransplanted human hepatocellular carcinoma (SMMC-7721 cell line).It was found that the changes occurred earlier in the cell membranes than in the nuclei during the course of TNF killing SMMC-7721 cell line and there was no special varieties around the necrotic...

Using light microscope and electron microscope,we observed the morphological changes in the SMMC-7721 human hepatocellular carcinoma cell line after it was exposed to the rabbit tumor necrosis factor (TNF)and the cytocidal effect of TNF on the heterotransplanted human hepatocellular carcinoma (SMMC-7721 cell line).It was found that the changes occurred earlier in the cell membranes than in the nuclei during the course of TNF killing SMMC-7721 cell line and there was no special varieties around the necrotic area in the heterotransplanted human hepatocellular carcinoma in the nude mice as compared with that appearing in SMMC-7721 cell line,In addition, we detected the DNA contents of TNF treated SMMC-7721 cells and control ones, but there was no significant difference of the DNA contents between them.Ace of ding to the results of this study, we think that the mechanism by wluch TNF exerts its tumour-selective killing effect is probably as follows.TNF binds to a specific plasma membrane receptor and then disturbs synthesis or assembly of cell membrane components, leading the changes of cell structure(for example, swollen microvilli, a number of vesicles and small holes on the surface of tumor cells), and the lysis of tumor cells.

应用光镜和电镜观察了肿瘤坏死因子(TNF)杀伤人肝癌细胞系(SMMC-7721)的过程,同时测定了其DNA含量的变化,并观察了TNF对裸鼠人肝癌移植瘤的作用。结果表明,TNF与SMMC-7721细胞接触后,癌细胞膜系统先有变化,而胞核的变化出现在后。作者认为TNF选择性杀伤肿瘤细胞的机理可能是TNF与癌细胞膜上某种正常细胞不具有的物质发生作用,引起癌细胞的膜系统损伤,终致细胞死亡。

A high level expression vector has been constructed,which contains PR PL promoter, cIts857 gene, multiple cloning sites ( MCS ) and two strong transcription terminators. Foreign gene with ATG signal can be inserted into the MCS, expressing non-fusion protein. Using this vector, we have expressed successfully the human interferon r,human interleukin-2 and human tumor necrosis factor. The foreign gene product accounts for more than 20% of the total cell protein.

我们组建了一个含P_RP_L自动子的原核高效表达载体,它同时含有cI调控基因、多酶切点和两个强的转录终止序列。带起始密码子ATG的外源基因可以插入启动子下游的多酶切点,表达非融合蛋白,产品可供临床使用。我们实验室已用它成功地表达了人γ干扰素、人白细胞介素-2和人肿瘤坏死因子等,表达量均占菌体总蛋白的20%以上。

 
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