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vaccine     
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  疫苗
    Study on Pseudorabies Virus Gene-deleted Vaccine, SA215 Strain
    伪狂犬病基因缺失疫苗SA215研究
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    Cloning, Expression and 'Bi-combined' Nucleic Acid Vaccine of Major Immunorelevant Genes of PRRSV and PRV
    PRRSV、PRV的分离、鉴定和主要免疫相关基因的克隆、表达及二联核酸疫苗研究
短句来源
    Strategy of Enhancing Immune Efficacy Elicited by DNA Vaccine
    增强DNA疫苗免疫效果的策略研究
短句来源
    The Study on the Gene-deleted Vaccine of Swine Pseudorabies
    猪伪狂犬病基因缺失疫苗研究
短句来源
    Mechanisms of in Vitro Delivering CD8~ +T Epitopes Through Attenuated Bacterica and Immunobiological Properties of Attenuated Salmonella Typhimurium Harbouring DNA Vaccine Against Newcastle Disease Virus
    重组减毒细菌运送CD8~+T细胞表位的机理及携带新城疫病毒DNA 疫苗鼠伤寒沙门氏菌的免疫生物学特性研究
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  疫苗的
    STUDY ON THE RECOMBINANT DNA VACCINE COEXPRESSING NEWCASTLE DISEASE VIRUS F GENE AND CHICKEN IL-2
    新城疫病毒F基因与鸡IL-2重组DNA疫苗的研究
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    The foundational study on Canine Adenovirus type 2 as a recombinant vaccine vector
    犬2型腺病毒基因重组活疫苗的基础研究
短句来源
    Sequence Analyses of Envelope Glycoprotein Genes of Chinese Isolates of Canine Distemper Virus and Immune Effect Induced by DNA Vaccine
    犬瘟热病毒中国分离株囊膜糖蛋白基因序列比较及其DNA疫苗的免疫效力
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    Studies on DNA Vaccine Against Porcine Reproductive and Respiratory Syndrome Virus
    猪繁殖与呼吸综合征病毒DNA疫苗的研究
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    Studies on ORF5 Gene Nucleic Acid Vaccine of Porcine Reproductive and Respiratory Syndrome Virus
    猪繁殖与呼吸综合征病毒ORF5核酸疫苗的研究
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  菌苗
    ERADICATION OF BRUCELLOSIS IN DAIRY HERDS WITH THE AID OF STRAIN 19 VACCINE TOGETHER WITH SIMPLIED CONTROL MEASURES
    采取简易隔离措施和使用19号菌苗清除牛群布鲁氏菌病的结果
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    STUDIES ON ENTEROTOXEMIA IN PIGLETS——Ⅱ. Vaccine and Immunization
    仔猪红痢的研究——Ⅱ、菌苗研究及免疫试验
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    DIAGNOSIS OF BOTULISM (TYPE C) AND STUDY ON THE VACCINE Ⅰ. DIAGNOSIS OF AETIOLOGY
    肉毒中毒(C型)的诊断与菌苗研究——Ⅰ.病源诊断
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    DIAGNOSIS OF BOTULISM (TYPE C) AND STUDY ON THE VACCINE II STUDY ON THE VACCINE
    肉毒中毒(C型)的诊断与菌苗研究——Ⅱ、菌苗研究
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    Challenge Test of Suckling Piglets Borne by Pregnant Sows being Immunized with Recombinant Live Vaccine E. coli C600 (pMM085)
    对应用遗传工程活菌苗E.coli C_(600)(pMMO85)免疫母猪所产仔猪的攻击试验
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    STUDIES ON AVIRULENT SWINE ERYSIPELAS VACCINE
    猪丹毒弱毒菌研究
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    STUDIES ON AN ATTENUATED LYOPHILIZED VACCINE STRAIN ST 171 OF STREPTOCOCCUS IN SWINE
    猪链球菌 ST171弱毒冻干的研究
短句来源
    EXPERIMENTAL STUDIES ON BRUCELLA SUIS STRAIN 2 ORALLY-ADMINISTRABLE VACCINE AGAINST SWINE BRUCELLOSIS
    猪种布鲁氏菌2号在猪体上免疫实验的研究
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    AN INVESTIGATION OF GOSLING PLAGUE IN HUNAN Ⅱ.THE MAKING AND APPLICATION OF GOSLING PLAGUE VACCINE
    湖南小鹅瘟防治研究 Ⅱ.小鹅瘟疫的研制及其应用效果
短句来源
    Experimental Studies on Vaccination of Chickens Using the Vero Cell Vaccine of Newcastle Disease Strain Ⅰ
    NDⅠ系Vero细胞对雏鸡的实验性免疫研究
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      vaccine
    TRANSFERSOMES FOR VACCINE DELIVERY: A POTENTIAL APPROACH FOR TOPICAL IMMUNIZATION
          
    Delivery of vaccine is a major impediment to ensuring vaccine efficacy and compliance.
          
    Existing vaccine delivery approaches have their limitations and these led to the development of novel approaches for vaccine delivery.
          
    Non-invasive vaccine delivery is in demand and for this skin appears to be a potential sites that elicit immune responses.
          
    This approach may present a general strategy for eliciting immune responses with DNA vaccine delivered by live bacterial vectors.
          
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    1.The efficacy of alum-precipitated vaccine produced from Beef Liver Infu- sion Broth was 8-15% higher than the formal-whole culture vaccine produced from the same medium,and 51% higher than the formal-whole culture vaccine prepared from peptone beef liver broth of USSR formula. 2.The rate of protection on guinea pigs by alum-precipitated vaccine and formal-whole culture vaccine was 93% and 42% respectively;but on cattle was 91% and 75% respectively. 3.Usiug guinea pigs,the efficacy...

    1.The efficacy of alum-precipitated vaccine produced from Beef Liver Infu- sion Broth was 8-15% higher than the formal-whole culture vaccine produced from the same medium,and 51% higher than the formal-whole culture vaccine prepared from peptone beef liver broth of USSR formula. 2.The rate of protection on guinea pigs by alum-precipitated vaccine and formal-whole culture vaccine was 93% and 42% respectively;but on cattle was 91% and 75% respectively. 3.Usiug guinea pigs,the efficacy of alum-precipitated vaccine,natural aggres- sion,artifical aggressin and toxoid was 100%,60%,40% and 0% respectively.

    1.以压气肉肝汤制成明矾苗及弗马林苗各3批,经海猪及绵羊比较其免疫效力后,一致证明明矾苗效力较佳。在海猪方面,明矾苗的保护力高于弗马林苗8—15%(第1,2,3批结果),局部破溃反应率低于弗马林苗11—45%(第2,3批结果),未保护者之平均死亡时间较弗马林苗推迟23—29小时(第1,3批结果)。在缅羊方面,主要表现是反应上的区别,弗马林苗免疫动物注射活菌以后的局部肿大及跛行反应数高于明矾苗22—42%(第1,2批结果),且出现全腿溃烂4头,而明矾苗无此现象,两者相差28%(第2批结果)。2.由压气肉肝汤制成的明矾苗与6批不同来源的(其中5批是由蛋白胨肉肝汤制成,1批不详)弗马林苗的效力比较,一致证明明矾苗的效力显著较佳。其中5批经过海猪试验,其平均保护率明矾苗为93%(保护(60)/(64)),弗马林苗为42%(保护(27)/(64)),两者相差51%。1批经过黄牛试验,其保护率明矾苗为91%,弗马林苗为75%,两者相差16%,免疫动物注射活菌后之局部反应,弗马林苗亦较严重而且较多。3.明矾苗、天然攻击素、人工攻击素及类毒素的效力比较,也一致证实明矾苗的效力优越。第1次试验免疫海猪注射菌液0.5毫升以后,明...

    1.以压气肉肝汤制成明矾苗及弗马林苗各3批,经海猪及绵羊比较其免疫效力后,一致证明明矾苗效力较佳。在海猪方面,明矾苗的保护力高于弗马林苗8—15%(第1,2,3批结果),局部破溃反应率低于弗马林苗11—45%(第2,3批结果),未保护者之平均死亡时间较弗马林苗推迟23—29小时(第1,3批结果)。在缅羊方面,主要表现是反应上的区别,弗马林苗免疫动物注射活菌以后的局部肿大及跛行反应数高于明矾苗22—42%(第1,2批结果),且出现全腿溃烂4头,而明矾苗无此现象,两者相差28%(第2批结果)。2.由压气肉肝汤制成的明矾苗与6批不同来源的(其中5批是由蛋白胨肉肝汤制成,1批不详)弗马林苗的效力比较,一致证明明矾苗的效力显著较佳。其中5批经过海猪试验,其平均保护率明矾苗为93%(保护(60)/(64)),弗马林苗为42%(保护(27)/(64)),两者相差51%。1批经过黄牛试验,其保护率明矾苗为91%,弗马林苗为75%,两者相差16%,免疫动物注射活菌后之局部反应,弗马林苗亦较严重而且较多。3.明矾苗、天然攻击素、人工攻击素及类毒素的效力比较,也一致证实明矾苗的效力优越。第1次试验免疫海猪注射菌液0.5毫升以后,明矾苗保护率为40%,天然攻击素及人工攻击素均为0%。第2次试验免疫海猪注射活菌液0.25毫升以后,明矾苗保护率为100%,天然攻击素为60%,人工攻击素为40%,类毒素为0%。

    1.In comparing the immunity of several lots of alum-precipitated vaccine prepared from beef liver infusion broth by cultivation for 2,5,10,15 and 20 days,the 2 days culture has been found most satifactory. 2.The efficacy of the vaccine on guinea pigs was influenced by the body weight.The lighter group showed higher protection. 3.The immunity in sheep began at 72 hours after the inoculation with 2 c.c. of alum-precipitated vaccine and it become solid after 124 hours. 4.The vaccine kept...

    1.In comparing the immunity of several lots of alum-precipitated vaccine prepared from beef liver infusion broth by cultivation for 2,5,10,15 and 20 days,the 2 days culture has been found most satifactory. 2.The efficacy of the vaccine on guinea pigs was influenced by the body weight.The lighter group showed higher protection. 3.The immunity in sheep began at 72 hours after the inoculation with 2 c.c. of alum-precipitated vaccine and it become solid after 124 hours. 4.The vaccine kept at a temperature of 10-30℃ for 21 months was in- jected into two groups of cattle,first group with 1 c.c.and seccond group with 0.5 c.c.Fourteen days after vaccination,these animals were challerged with 1.5 c.c.of virulent culture the first group showed a pretection of 100% and the second group only 75%.

    1.前后2次以2,5,10,15,及20天培养的菌液分别制成明矾菌苗,以海猪比较其效力,结果一次因注射菌液量较小致各种时间培养苗,不显示有区别。另一次则以2天培养苗效力效佳。2.前后2次以5批菌苗,以不同体重的海猪试其免疫力,结果一致表现体重大的(560—700克)效力差,体重小的(320—450)效力好。前者之免疫率为25—50%;平均为42%;后者为75—100%,平均为92%。3.以明矾苗注射缅羊后,3天开始有免疫力,满6天有坚强的免疫力。4.明矾苗在10—30℃保存21个月以后,其效力仍然良好。以1毫升剂重免疫黄牛,获得免疫力100%,0.5毫升获得免疫力75%。

    In order to find a,simplified but dependable method for active immunization against swine erysipelas and hog-cholera,a mixed bivalent vaccine was triec and the results may be briefly summarized as follows: (1) This vaccine was composed of an attenuated strain of Erysipelothrix rhusiopathiae mixed with a lapinized hog-cholera virus in a definite proportion,suspended in diluted milk powder solution and 1% sucrose,and finally lyophilized. (2) The mixed bivalent vaccine was diluted with 1.2% Al(OH)_3...

    In order to find a,simplified but dependable method for active immunization against swine erysipelas and hog-cholera,a mixed bivalent vaccine was triec and the results may be briefly summarized as follows: (1) This vaccine was composed of an attenuated strain of Erysipelothrix rhusiopathiae mixed with a lapinized hog-cholera virus in a definite proportion,suspended in diluted milk powder solution and 1% sucrose,and finally lyophilized. (2) The mixed bivalent vaccine was diluted with 1.2% Al(OH)_3 gel,andi 2 ml of this vaccine were administered intramuscularly for pig immunization resulting with 100% immunity to both diseases at the end of 7 months and 75% to hog-cholera and 100% to swine erysipelas at the end of 9 months. (3) The keeping quality of the vaccine was tested and it was found that excellent antigenicity was still maintained at the end of 6 months under a temperature condition varying from-8℃ to,35℃. (4) Safety test of the vaccine was carried out both in laboratory and out in the field,and a total of 16,374 pigs of different breeds at various ages was used for the test with only 0.22% of the total animals showing some vaccination reactions but no mortality.A general survey was made 7 months after vaccination and neither swine erysipelas nor hog-cholera cases were found among tested animals.

    1.在我院研究猪丹毒弱毒冻干菌苗的基础上,試制成功一种猪瘟、猪丹毒弱毒混合冻干疫苗,經用小动物和猪进行試驗,証明安全有效。 2.一次肌肉注射混合冻干疫苗2毫升,已知免疫期可达9个月,免疫猪对猪瘟或猪丹毒均有良好的抵抗力。 3.混合冻干疫苗性质稳定,在—8°—35℃的不同溫度条件下,保存6个月后对猪安全并仍有坚强的效力。 4.疫苗在江苏省鎮江等地大面积推广应用16,374剂,反应率仅占0.22%,7个月后調查沒有猪再感染猪瘟或猪丹毒病例。 5.报告内对混合冻干疫苗的制造方法,保护剂的选择等亦作了介紹。

     
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