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prostatic lesions
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  前列腺病变
     Methods:Immunohistochemical staining was used for detection of expression of P504S,p63, and basal cell-specific anti-cytokeratin antibody(CK34βE12)in various prostatic lesions.
     方法:采用免疫组织化学技术,检测P504S、p63及CK34βE12在各类前列腺病变中的表达。
短句来源
     Purpose To investigate the expression and significance of E-cadherin (E-cad), p16 and ER in prostatic lesions.
     目的 探讨抑癌基因E cadherin(E cad)、p16蛋白及ER在前列腺病变组织中的表达及临床意义。
短句来源
     Expression of E-cadherin, p16 and estrogen receptor in prostatic lesions and its clinical implication
     前列腺病变中E-cadherin、p16和ER表达及意义
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     Relationship between apoptosis and expression of bcl-2,bax and PCNA protein in prostatic lesions
     前列腺病变组织中细胞凋亡与bcl-2、bax、PCNA表达
短句来源
     Methods Expressions of P504s and p63 in benign and malignant prostatic lesions were observed by immunohistochemical staining.
     方法采用免疫组化二步法,观察P504s和基底细胞标记物p63在不同前列腺病变组织中的表达情况。
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  “prostatic lesions”译为未确定词的双语例句
     The positive rate of P504S expression was 8.2%(8/97)in benign prostatic lesions and 39.5%(15/38)in high grade intraepithelial neoplasias(HGPIN).
     P504S在良性前列腺痛变上皮中表达率是8.2%(8/97),在前列腺高级别上皮内瘤(high grade intraepithelial neoplasias,HGPIN)中表达率是39.5%(15/38)。
短句来源
     Expression of nucleolar organizer region associated protein (AgNOR) and proliferating cell nuclear antigen (PCNA) were assayed using silver-staining and immunohistochemical methods in 74 cases of benign and malignant prostatic lesions.
     为探讨早期诊断前列腺良、恶性病变的生物学行为指标,采用银染色和免疫组织化学染色法对74例前列腺良、恶性病变组织中细胞核仁组成区嗜银蛋白(AgNOR)和增殖细胞核抗原(PCNA)进行检测。
短句来源
     11C-choline uptake was analyzed semiquantitatively by using the maximum standardized uptake values (SUVmax) and tumor-to-background (T/B) ratio for prostatic lesions.
     测量最高标准化摄取值(SUVmax)并计算前列腺病灶与肌肉组织SUVmax的比值T/B。
短句来源
     Results of Preliminary clinical application of this new method in a group of 31 cases with the prostatic diseases showed that TPA was helpful for detecting the prostatic lesions(29/31),especially in evaluation of the prostatic hyperplasia(23/23).
     经病理证实组31例临床初步应用,结果表明这一新方法有助于多种前列腺疾病的诊断(29/31),对前列腺增生症尤其有用(23/23)。
短句来源
     ObjectiveTo investigate the clinicopathological features of the needle biopsies of prostatic lesions and to evaluate the value of 34βE12 immunostaining for the diagnosis of prostatic carcinoma.
     目的 探讨前列腺穿刺标本的临床及病理学特征 ,评价细胞角蛋白 34βE12免疫组化染色在诊断中的价值。
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  相似匹配句对
     Image cytometry in prostatic lesions
     前列腺病变的DNA图像分析研究
短句来源
     Expreesion of EGF-R in benign and malignant prostatic lesions
     表皮生长因子受体在前列腺良、恶性病变组织中的表达
短句来源
     PRECANCEROUS LESIONS
     癌前病变
短句来源
     Prostatic Commissurotomy
     前列腺联合部切开术(附7例报告)
短句来源
     Fibrotic prostatic hyperplasia
     纤维增生型前列腺增生症
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  prostatic lesions
With the usage of prostate specific antigen (PSA) it was seen that all of the malignant and benign prostatic lesions stained positively.
      
High molecular weight anti-cytokeratin antibodies (HMW anti-cytokeratin) stained basal cells both in all normal prostatic tissue and benign prostatic lesions, but in the majority of cancers (70%, n=14) negative immunoreactivity was seen.
      
In order to differentiate benign from malignant prostatic lesions, 42 patients were evaluated using the prostate specific antigen density (PSAD) test.
      
Silver-stained nucleolar organiser regions (AgNORs) were studied in 10 hyperplastic, 5 intra-epithelial neoplastic and 30 malignant prostatic lesions.
      
Knowledge of the appearance of normal and benign conditions of the prostate on ultrasound is required for the identification of prostatic lesions that are suspected of being carcinomatous.
      
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A newly improved transperineal scanning technique with real-time ultrasound for visualizing the prostate has been introduced.Series of prostatic sonograms with relatively high quality of image could be easily obtaned when several technical points were followed.The transperineal approach(TPA) had a 99%(108/109) of successful rate of imaging compared with a 89%(96/109) by using the abdominal approach(TAA,P<0.05) in the normal group.The obvious advantage of TPA over TAA was that the important structures s.uch as...

A newly improved transperineal scanning technique with real-time ultrasound for visualizing the prostate has been introduced.Series of prostatic sonograms with relatively high quality of image could be easily obtaned when several technical points were followed.The transperineal approach(TPA) had a 99%(108/109) of successful rate of imaging compared with a 89%(96/109) by using the abdominal approach(TAA,P<0.05) in the normal group.The obvious advantage of TPA over TAA was that the important structures s.uch as the inner and the outer gland of the prostate could be well-visualized constantly.Results of Preliminary clinical application of this new method in a group of 31 cases with the prostatic diseases showed that TPA was helpful for detecting the prostatic lesions(29/31),especially in evaluation of the prostatic hyperplasia(23/23).The authors believed that TPA could be avery good complement to using the ordinary TAA in clinical practice and that a combination of TPA and TAA would form an ideal parenterai prostate scannig technique

作者介绍了一种经会阴实时超声扫查前列腺的新技术。遵循若干技术要点能容易地获得系列质量较高的前列腺声像图。会阴途径(TPA)超声显像成功率在正常组为99%(108/109)而腹壁途径(TAA)成功率仅89%(96/109,P<0.05)。TPA显然优于TAA之处在于,它总能清晰地显示前列腺内腺,外腺等重要结构。经病理证实组31例临床初步应用,结果表明这一新方法有助于多种前列腺疾病的诊断(29/31),对前列腺增生症尤其有用(23/23)。作者认为,TPA的临床应用能够很好地补充TAA之不足;TPA和TAA的联合应用,可以构成比较理想的体腔外前列腺扫查技术。

An expression of ras oncogene protein (p21) was assessed with immunohistochemistry in normal, dysplasia, benign hyperplasia, chronic prostatitis and prostatic carcinomatous tissues. The results showed that the positivity rate of p21 was higher in prostatic carcinoma than that in other prostatic lesions and was markedly correlated to histologic tumor grade. The expression level of p21 was more intentive in prostatic dysplasia surrounding carcinoma than that in simple prostatic dysplasia. It...

An expression of ras oncogene protein (p21) was assessed with immunohistochemistry in normal, dysplasia, benign hyperplasia, chronic prostatitis and prostatic carcinomatous tissues. The results showed that the positivity rate of p21 was higher in prostatic carcinoma than that in other prostatic lesions and was markedly correlated to histologic tumor grade. The expression level of p21 was more intentive in prostatic dysplasia surrounding carcinoma than that in simple prostatic dysplasia. It is suggested that overexpression of ras oncogene p21 product may play an important role in progressing from dysplasia to cancer and may be used as a new tumor marker for assessment of biological behavior of prostatic carcinoma.

用抗ras癌基因蛋白质产物p21单克隆抗体SCI-oncogema I,采用常规ABC免疫组织化学方法检测了66例前列腺癌、46例前列腺非典型增生、20例慢性前列腺炎、50例良性前列腺增生和6例正常前列腺组织石蜡标本中p21的表达,结果显示,前列腺癌的阳性表达率明显高于其他几组病变(P<0.01),其阳性表达率随肿瘤组织学分级增高而增高。前列腺癌周的不典型增生组织对p21的反应强度显著高于单纯性不典型增生组织。上述结果说明,ras癌基因产物p21的过量表达,在前列腺非典型增生向前列腺癌的发展过程中起着重要作用,并且可以作为一种新的肿瘤标记物来估计前列腺癌的生物学行为。

One hundred and fifty specimens of benign and malignnat prostatic tissues were stained with argyrophil nucleolar organizer region(AgNOR) technique and the AgNOR granules were counted. It was found that the average number of AgNOR granules was gradually increased in the order of normal prostatic tissue, benign prostatic hyperplasia, prostatic atypical hyperpiasia and prostatic carcinoma and the largest in prostatic carcinoma. The number of AgNOR granules was comparatively small in the well-differentiated large...

One hundred and fifty specimens of benign and malignnat prostatic tissues were stained with argyrophil nucleolar organizer region(AgNOR) technique and the AgNOR granules were counted. It was found that the average number of AgNOR granules was gradually increased in the order of normal prostatic tissue, benign prostatic hyperplasia, prostatic atypical hyperpiasia and prostatic carcinoma and the largest in prostatic carcinoma. The number of AgNOR granules was comparatively small in the well-differentiated large acinous adenocarcinoma.The AgNOR granules could be classified into 4 types according to their shape, size and number. They were the small round granules, large round granules,satellite-like round granules and irregular granules, It is believed that AgNOR staining is of diagnostic and differential diagnostic significance for most cases of prostatic carcinoma and benign prostatic lesions. In addition, there might be certain ralationship between the type of AgNOR granules and the pathological nature of the prostatic lesions.

应用嗜银核仁组成区(AgNOR)技术对150例良、恶性前列腺组织进行了检测。结果表明从正常前列腺、良性前列腺增生(BPH)、前列腺非典型增生(PAH)与前列腺癌(PC)的AgNOR颗粒均数值呈递增性增高,PC的颗粒均数值明显高于正常及其它各组,PAH颗粒数量界于BPH与PC之间。PC组的分类统计表明在TUR术组、大泡性高分化腺癌中AgNOR颗粒数偏低。根据AgNOR颗粒的形态、大小与数目,作者将其分为:小圆颗粒、大圆颗粒、卫星状圆形颗粒及不规则异形颗粒4种类型。结果提示AgNOR技术对大多数PC与前列腺良性病变具有诊断与鉴别诊断价值,也提示PAH为PC的癌前病变。并表明不同的颗粒类型与不同病理类型的PC有一定关系。

 
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