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   mesylate 在 药学 分类中 的翻译结果: 查询用时:0.181秒
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mesylate
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  甲磺酸
    Determination of Pefloxacin Mesylate Concentration in Human Plasma by High Performance Liquid Chromatography(HPLC)
    高效液相色谱法测定人血浆中甲磺酸培氟沙星浓度
短句来源
    PHASEⅢCLINICAL TRAIL OF PEFLOXACIN MESYLATE
    甲磺酸培氟沙星Ⅲ期临床试验
短句来源
    DETERMINATION OF DISSOLUTION OF PERGOLIDE MESYLATE TABLETS
    甲磺酸培高利特片溶出度的测定
短句来源
    Objective A HPLC method was established for the determination of ropivacaine mesylate injection and its related substances.
    目的建立一种用反相高效液相色谱法(RP-HPLC法)测定甲磺酸罗哌卡因注射液含量及有关物质的方法。
短句来源
    Result: Hyperglycemia occurred in 13 patients received Gatifloxacin mesylate for injection and one with Gatifloxacin and sodium chloride injection. The peak value of blood glucose after usage of Gatifloxacin, differing during 1-10days, was up to 51.67 mmol/L,down to 3.23 mmol/L ,and induced hyperisotonic olighydria. Hypoglycaemia happened only in 1 patient.
    结果:应用甲磺酸加替沙星注射液(Gatifloxacin mesylate for injection)13例、加替沙星氯化钠注射液(Gatifloxacin and sodiumchloride injection)1例发生治疗相关血糖异常,用药后1~10天血糖值均有明显波动,达3.23~51.67mmol/L,仅1例用药1天出现低血糖后转为高血糖,其余均为高血糖。
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  “mesylate”译为未确定词的双语例句
    Methods One hundred and twenty C57BL/6 mice were randomly divided into control group,model group,dexamethasone group and imatinib mesylate group (with 30 mice each).
    方法120只C57BL/6小鼠被随机分为对照组、模型组、地塞米松组和格列卫组,每组30只。
短句来源
    In imatinib mesylate and dexamethasone groups alveolitis grades and PF induced by bleomycin were obviously alleviated. The concentration of HYP and expression of PDGF-BB in lung tissues decreased in imatinib mesylate and dexamethasone groups compared with those in model group (P<0.05 or P<0.01).
    与模型组比较,格列卫组与地塞米松组的肺泡炎分级和肺纤维化程度均明显减轻,HYP含量和肺组织PDGF-BB表达均降低(P<0.05或P<0.01);
短句来源
    Effect of tyrosine kinase inhibitor Imatinib mesylate on proliferation, differentiation and apoptosis of Kasumi-1 leukemia cell line
    伊马替尼体外诱导Kasumi-1细胞增殖、分化与凋亡作用
短句来源
    Study on bioequivalence of rosiglitazone phosphonate and rosiglitazone mesylate
    依替膦酸罗格列酮与马来酸罗格列酮的生物等效性研究
短句来源
    Experimental study on the effects of doxazosin mesylate on lipemia in rabbit
    多沙唑嗪控释片对血脂影响的实验研究
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  mesylate
Imatinib mesylate (imatinib) is a new generation preparation that is now successfully used for treatment of cancer, particularly for chemotherapy of chronic myeloid leukemia (CML).
      
Spectrophotometric Methods for the Determination of Nelfinavir Mesylate
      
Three visual spectrophotometric methods are described for the assaying of nelfinavir mesylate (NEL) in either bulk form or dosage forms.
      
Binding interactions of pefloxacin mesylate with bovine lactoferrin and human serum albumin
      
The binding of pefloxacin mesylate (PFLX) to bovine lactoferrin (BLf) and human serum albumin (HSA) in dilute aqueous solution was studied using fluorescence spectra and absorbance spectra.
      
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Pharmacokinetics and bioavailability of tablets of pefloxacin (1)mesylate were studied in six dogs after single administration at dosage of 10mg/kg. The plasma concentrations of 1 were measured using HPLC procedure.After oral administration, the curve of 1 concentration vs time was fit for onecompartment model,t1/2 was 13.837±2.499h,and AUC was 19.305±5.702μgh/ml.After iv administration,the curve of 1 concentration vs time was fit for twocompartment model,t1/2 was 16.161±4. 604h,and AUC was 20.852±5.178μgh/ml....

Pharmacokinetics and bioavailability of tablets of pefloxacin (1)mesylate were studied in six dogs after single administration at dosage of 10mg/kg. The plasma concentrations of 1 were measured using HPLC procedure.After oral administration, the curve of 1 concentration vs time was fit for onecompartment model,t1/2 was 13.837±2.499h,and AUC was 19.305±5.702μgh/ml.After iv administration,the curve of 1 concentration vs time was fit for twocompartment model,t1/2 was 16.161±4. 604h,and AUC was 20.852±5.178μgh/ml. The absolute bioavailability of the tablets of 1 mesylate was 92.606±13.214%.

犬6只经口服和静注交叉给药,单次给药剂量10mg/kg。血药浓度以HPLC测定。口服和静注后药时曲线分别符合有吸收的一室模型和无吸收的二室模型,消除半衰期为13.837±2.499及16.161±4.604h,药时曲线下面积为19.305±5.702及20.852±5.178μgh/ml。片剂口服的绝对生物利用度为92.606±13.214%。

reversed-phase HPLC determination of Pefloxacin mesylate in human plasma was established.Pefloxacinmesylate can be separated on Zorbax ODS C_(18) column with a mobile phase of MeOH-0. 04mol/L H_3PO_4 solution(80 : 20,V/V)adjusted to with triethylamine pH 3. 0 and detected at 276nm, The flow rate was lmL/min, Thelinear range was 6.01 × 10 ̄(-8) to 3.01 × 10 ̄(-5) mol/L(γ=0. 9998)and the detection limit was 6.01 × 10 ̄(-8)mol/L.The average recovery was 97.57±3.04%, and the coefficients of variation were 3.29%and...

reversed-phase HPLC determination of Pefloxacin mesylate in human plasma was established.Pefloxacinmesylate can be separated on Zorbax ODS C_(18) column with a mobile phase of MeOH-0. 04mol/L H_3PO_4 solution(80 : 20,V/V)adjusted to with triethylamine pH 3. 0 and detected at 276nm, The flow rate was lmL/min, Thelinear range was 6.01 × 10 ̄(-8) to 3.01 × 10 ̄(-5) mol/L(γ=0. 9998)and the detection limit was 6.01 × 10 ̄(-8)mol/L.The average recovery was 97.57±3.04%, and the coefficients of variation were 3.29%and 5. 08% for within-day and day-to-day tests respectively.

建立了一种测定人血浆中甲磺酸培氟沙星的匠相液相色谱方法,用的是ZorbaxODSC_(18)柱和用三乙醇胺调节成pH为3.0的甲醇-0.04mol/LH_3PO_4溶液(80:20,V/V)的流动相,检测在276nm处进行,流量为1mL/min,线性范围是6.01×10 ̄(-8)~3.01×10 ̄(-5)mol/L(γ=0.9998),检测极限为6.01×10 ̄(-8)mol/L,平均回收率为97.57±3.04%,日内与日间的CV分别为3.29%和5.08%。

An open,randomized/crossover study on the bioavailability of Pefloxacin mesylate capsules and tablets in a single oral dose of 400mg have been achieved in 10 healthy male volunteers. The plasma drug concentrations were measured by HPLC. The peak plasma level of Pefloxacin for capsules and tablets averaged 4.14±0. 89 and 4.05±1.02μg/ml obtained at 1.04±0. 26 and 1.19±0.48 hours and the AUC obtained were 51.99±14.52 and 51.82±17.10μg. h/ml. The relative bioavailability of capsules vs,tablets was 102.8%and...

An open,randomized/crossover study on the bioavailability of Pefloxacin mesylate capsules and tablets in a single oral dose of 400mg have been achieved in 10 healthy male volunteers. The plasma drug concentrations were measured by HPLC. The peak plasma level of Pefloxacin for capsules and tablets averaged 4.14±0. 89 and 4.05±1.02μg/ml obtained at 1.04±0. 26 and 1.19±0.48 hours and the AUC obtained were 51.99±14.52 and 51.82±17.10μg. h/ml. The relative bioavailability of capsules vs,tablets was 102.8%and no significant differences in pharmacokinetic parameters were observed in the 2 dosage forms.

10名健康中国男性受试者单剂量随机交叉口服400mg国产甲磺酸培氟沙星胶囊及片剂后,采用HPLC法测定血浆药物浓度。结果表明服用胶囊及片剂后血药浓度分别于1.04±0.26和1.19±0.48h达到峰值4.14±1.02和4.05±0.89μg/ml,药时曲线下面积分别为51.99±N.52和51.82±17.10μg·h/ml。甲磺酸培氟沙星胶囊的相对生物利用度下为102.8%。

 
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