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susceptible rates
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  敏感率
    Imipenem ceftazidime, amikacin, ciprofloxacin, piperacillin and cefotaxime were the most active agents against Gram - negative organisms including Enterobacteriaceae and glucose nonfermenters, while the susceptible rates were significantly lower as compared with the data in 1996 and 1999.Condutions The results suggested that it is an urgent need for surveillance of bacteria resistance in different districts and rational use of antimicrobial agents should be emphasized during clinical therapy.
    亚胺培南、头孢他啶、阿米卡星、环丙沙星、哌拉西林、头孢噻肟对革兰阴性菌(包括肠杆菌科及非发酵菌)有良好抗菌活性,但与1996年、1999年监测资料比较,敏感率逐年下降。 结论 临床细菌耐药性日益严重,应在不同地区开展耐药性监测工作,强调临床合理应用抗菌药物。
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  susceptible rates
The non-susceptible rates for chloramphenicol, and co-trimoxazole were similar for the two groups.
      


Objective To report the surveillance data on bacterial resistance in Hubei hospitals.Methods The diameters of the inhibition zone of clinical bacterial around antibiotic susceptibility test discs in IS Hubei province hospitals were computerfiled and analysed by the software of "WHONET- 5" according to NCCLS published in 1999.Results A total of 10241 clinical isolates were collected from January 1 to December 31, 2000. Coagulase negative staphylococci (CNS), E.Coli, P.aeruginosa, S.areus, Klebsiel-la spp, Enterococcus...

Objective To report the surveillance data on bacterial resistance in Hubei hospitals.Methods The diameters of the inhibition zone of clinical bacterial around antibiotic susceptibility test discs in IS Hubei province hospitals were computerfiled and analysed by the software of "WHONET- 5" according to NCCLS published in 1999.Results A total of 10241 clinical isolates were collected from January 1 to December 31, 2000. Coagulase negative staphylococci (CNS), E.Coli, P.aeruginosa, S.areus, Klebsiel-la spp, Enterococcus spp, Enterobacter spp, Acinetobacter spp were the main microorganisms.Oxacillin resistant strains accounted for 22.0% and 69.9% of S.aureus and CNS respectively; In Enterococcus spp.vancomycin resistant strains accounted for 3.1% and 1.9% of E.fecalis and E.fecium, respectively.Imipenem ceftazidime, amikacin, ciprofloxacin, piperacillin and cefotaxime were the most active agents against Gram - negative organisms including Enterobacteriaceae and glucose nonfermenters, while the susceptible rates were significantly lower as compared with the data in 1996 and 1999.Condutions The results suggested that it is an urgent need for surveillance of bacteria resistance in different districts and rational use of antimicrobial agents should be emphasized during clinical therapy.

目的 探讨2000年湖北省临床分离菌对抗菌药物的耐药状况。方法 将湖北地区15所医院纸片扩散法药敏试验的抑菌环直径输入计算机。根据1999年美国临床实验室标准委员会颁布的准则,采用“WHONET-5”软件完成统计分析。结果 临床10 241株分离菌中,最常见的菌种依次为凝固酶阴性葡萄球菌、大肠埃希菌、铜绿假单胞菌、金黄色葡萄球菌、克雷伯菌属、肠球菌属、肠杆菌属,不动杆菌属等。22.0%的金黄色葡萄球菌和69.9%的凝固酶阴性葡萄球菌对苯唑西林耐药,对其他药物的耐药率也高。肠球菌中万古霉素耐药株分别占粪肠球菌和屎肠球菌的3.1%和1.9%。亚胺培南、头孢他啶、阿米卡星、环丙沙星、哌拉西林、头孢噻肟对革兰阴性菌(包括肠杆菌科及非发酵菌)有良好抗菌活性,但与1996年、1999年监测资料比较,敏感率逐年下降。结论 临床细菌耐药性日益严重,应在不同地区开展耐药性监测工作,强调临床合理应用抗菌药物。

Objective To determine the drug-resistance rates of gram-positive cocci isolated from patients with hospital acquired infection (HAI) or community acquired infection (CAI) in 34 study wards of 13 hospitals located at different areas in China. Methods According to the previous protocol, from July 1 st 2000 to June 30 th 2001, a total of 2401 pathogenic strains were isolated from 13 hospitals. Among them, 805 strains of gram-positive cocci were collected for in vitro susceptibility test using international...

Objective To determine the drug-resistance rates of gram-positive cocci isolated from patients with hospital acquired infection (HAI) or community acquired infection (CAI) in 34 study wards of 13 hospitals located at different areas in China. Methods According to the previous protocol, from July 1 st 2000 to June 30 th 2001, a total of 2401 pathogenic strains were isolated from 13 hospitals. Among them, 805 strains of gram-positive cocci were collected for in vitro susceptibility test using international standard plate dilution method. According to the criteria of guidelines of NCCLS (2001), MIC 50 and MIC 90 were detected to represent the antibacterial activity of antimicrobial agents and R%, I%, and S%, were calculated to show the resistant, intermediate and susceptible rates of the bacteria to the compounds tested. Results The detectable rates of methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant Staphylococcus epidermidis (MRSE) were 37.4%(89/238)and 33.8%(51/151)respectively. Among a total of 238 strains of S. aureus, 139 were isolated from patients with CAI and 37 were from HAI patients, the rate of MRSA from HAI patients (89.2%, 33/37)was significantly higher than that of MRSA from CAI patients (30.2%, 42/139)(P<0.01) The total resistant rate of penicillin resistant Streptococcus pneumoniae (PRSP) was 26.7% (8/30), including a R% of 3.3%(1/30) and an I% of 23.3% (7/30). 331 strains of Enterococcus were isolated, including 178 strains from the study wards and 153 strains from other wards. The ratio of number of strains of E. faecalis to E. faecium was 6.8∶1 (286/42). The rate of ampicillin resistant E. faecium (AREF) was 73.8%(31/42), significantly higher than the rate of ampicillin resistant E. faecalis (16.4%, 47/286). Neither strains of S. aureus nor strains of coagulase negative Staphylococcus were found resistant to vancomycin. No strains of Enterococcus were found resistant to vancomycin, the intermediate rates of E. faecalis and E. faecium to vancomycin were 3.5% (10/286) and 9.5%(4/42) respectively. All strains of Enterococcus were found 100% susceptible to teicoplanin. Conclusion The resistance patterns of Gram-positive cocci including MRSA, PRSP, and AREF are similar to the results of the 1998-1999 surveillance. No strain of vancomycin- resistant Staphylococcus aureus, including VRSA and VISA or vancomycin resistant enterococcus, VRE is found in this study.

目的 探讨我国不同地区医院获得性感染 (HAI)和社区获得性感染 (CAI)患者中革兰阳性球菌耐药情况。方法 按原设计方案对 13家医院从 2 0 0 0年 7月 1日至 2 0 0 1年 6月 30日年度内分离的 2 40 1株致病菌中的 80 5株革兰阳性球菌采用国际标准平皿二倍稀释法进行体外敏感试验 ,按2 0 0 1年美国临床实验标准委员会 (NCCLS)指导原则的标准 ,测得最低抑菌浓度 (MIC50 )、MIC90 表示抗菌药物的抗菌活性 ,并计算出所测细菌对抗菌药物的耐药率 (R % )、中介率 (I% )和敏感率 (S % )。结果 从住院感染患者中分离到 2 38株金黄色葡萄球菌 ,甲氧西林耐药金黄色葡萄球菌 (MRSA)与甲氧西林耐药表皮葡萄球菌 (MRSE)的检出率分别为 37 4% ( 89/ 2 38)和 33 8% ( 5 1/ 15 1)。其中从CAI患者与HAI患者中分离的金黄色葡萄球菌数分别为 139株和 37株 (另有 6 2株不明确是CAI还是HAI)。HAI患者中MRSA检出率为 89 2 % ( 33/ 37) ,显著高于CAI患者中MRSA检出率 30 2 % (...

目的 探讨我国不同地区医院获得性感染 (HAI)和社区获得性感染 (CAI)患者中革兰阳性球菌耐药情况。方法 按原设计方案对 13家医院从 2 0 0 0年 7月 1日至 2 0 0 1年 6月 30日年度内分离的 2 40 1株致病菌中的 80 5株革兰阳性球菌采用国际标准平皿二倍稀释法进行体外敏感试验 ,按2 0 0 1年美国临床实验标准委员会 (NCCLS)指导原则的标准 ,测得最低抑菌浓度 (MIC50 )、MIC90 表示抗菌药物的抗菌活性 ,并计算出所测细菌对抗菌药物的耐药率 (R % )、中介率 (I% )和敏感率 (S % )。结果 从住院感染患者中分离到 2 38株金黄色葡萄球菌 ,甲氧西林耐药金黄色葡萄球菌 (MRSA)与甲氧西林耐药表皮葡萄球菌 (MRSE)的检出率分别为 37 4% ( 89/ 2 38)和 33 8% ( 5 1/ 15 1)。其中从CAI患者与HAI患者中分离的金黄色葡萄球菌数分别为 139株和 37株 (另有 6 2株不明确是CAI还是HAI)。HAI患者中MRSA检出率为 89 2 % ( 33/ 37) ,显著高于CAI患者中MRSA检出率 30 2 % ( 42 / 139) (P <0 0 1)。青霉素耐药肺炎链球菌 (PRSP)的检出率 (R % +I% )为 3 3 % ( 1/ 30 ) +2 3 3% ( 7/ 30 ) ,总耐药率为 2 6 6 % ( 8/ 30 )。从研究病房分离到肠球菌 178株 ,非研究病房分离到 15 3株 ,共计 331株。其中粪肠球菌 2 86株、屎肠球?

Objective To investigate infection status of hepatitis B virus among some enterprises workers in Guangzhou region. Methods A cross-sectional investigation on hepatitis B virus markers was conducted in four factories workers from 2001 to 2003. Results 3 117 worker's serum was tested for HBsAg, HBsAb, HBeAg, HBeAb and HBcAb.The result shows:606 cases were negative both in HBsAg and in HBsAb(19.44%). 2 047 cases were positive in HBsAb(65.67%). 464 cases were positive in HBsAg(14.89%). Among 606 negative...

Objective To investigate infection status of hepatitis B virus among some enterprises workers in Guangzhou region. Methods A cross-sectional investigation on hepatitis B virus markers was conducted in four factories workers from 2001 to 2003. Results 3 117 worker's serum was tested for HBsAg, HBsAb, HBeAg, HBeAb and HBcAb.The result shows:606 cases were negative both in HBsAg and in HBsAb(19.44%). 2 047 cases were positive in HBsAb(65.67%). 464 cases were positive in HBsAg(14.89%). Among 606 negative cases both in HBsAg and in HbsAb, 56 cases were only positive in HBeAb or HBcAb and in the both(1.80%). Conclusion HBsAg positive rate was higher in our study than national average level. The susceptible rate was higher in G.Z. region(the negative rates both in HBsAg and in HBsAb were 19.44%). It is necessary to vaccinate hepatitis B virus earlier to prevent from infection of hepatitis B, liver cirrhosis and hepatocellular carcinoma.

目的 了解广州地区部分企业职工乙肝病毒感染情况。方法 对 2 0 0 1~ 2 0 0 3年在我院作健康体检的广州地区部分企业职工的乙肝“两对半”体检资料进行分析。结果 调查 3 117例 (男 1860 ,女 12 5 7)企业职工 ,全部静脉抽血作乙肝病毒感染标志物“两对半”(HBsAg、HBsAb、HBeAg、HBeAb、HBcAb 5项 )检查 ,其中HBsAg和HBsAb均阴性 60 6人( 19 44 % ) ,HBsAb阳性 2 0 47人 ( 65 67% ) ,HBsAg阳性 464人 ( 14 89% )。而HBsAg和HBsAb阴性的 60 6人中HBeAb或HBcAb阳性 ,或两者同时阳性 5 6人 ( 1 80 % )。结论 本调查职工HBsAg阳性率为 14 89% ,高于全国平均水平 ;HBsAb阳性率为 65 67% ;HBsAg和HBsAb均为阴性占 19 44 % ,易感者比率较高 ,有必要及早采取注射乙肝疫苗等有效干预措施 ,降低受感染的危险性 ,减少乙型肝炎、肝硬化及肝癌的发病率。

 
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