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anti hiv
相关语句
  抗hiv
     Construction and expression of human anti HIV 1 integrase single chain antibody gene
     人源抗HIV-1整合酶单链抗体基因的构建及表达
短句来源
     To improve the accuracy of anti HIV detection,the serum for internal quality control was prepared.
     为了提高抗 HIV的检测质量 ,进行室内质控以鉴别诊断试剂的质量和控制操作误差 ,试制了抗 HIV室内质控血清。
短句来源
     AIM: To investigate the effect of momordica anti HIV protein of M r being 30 000 (MAP30) on HBV expression by laser scanning confocal microscopy.
     目的 :研究Mr 为 30 0 0 0的苦瓜抗HIV蛋白 (MAP30 )对 2 .2 .15细胞内HBV基因表达的抑制作用。
短句来源
     The titer of anti HIV antibody and the IFN γ level in mice immunized with the pVAX1 GP120 were higher than those in mice immunized with pVAX1 respectively ( P <0.01).
     与空载体pVAX1组相比较 ,pVAX1 GP12 0免疫组小鼠血清抗HIV 1gp12 0抗体的滴度和IFN γ的水平均升高 ,两者差异显著 (P <0 .0 1)。
短句来源
     Methods HBsAg,Anti HCV,Anti HIV were detected by enzyme linked immunoadsorbent assay (ELISA).
     方法 HBsAg、抗 HCV、抗 HIV检测采用酶联免疫吸附法 (ELISA) ;
短句来源
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  抗艾滋病
     The experiments show that this kind of compounds are effective inhibitor with low toxicity and high anti HIV 1 activity.
     配合物抗艾滋病病毒(HIV1)活性的研究表明,此类配合物具有较低的细胞毒性及较高的抗艾滋病病毒活性
短句来源
     HIV integrase (IN) is a viral encoded protein that catalyzes viral DNA into the host genome. Therefore, IN offers a unique target for the development of novel anti HIV and anti AIDS therapeutics.
     HIV整合酶是一种病毒编码蛋白质 ,它催化病毒DNA整合进入宿主基因组 ,这为开发新的抗HIV和抗艾滋病疗法提供了一个重要的靶标。
短句来源
     The anti HIV activities and toxicities of these compounds have been determined in human T lymph cells MT 4. It has been found that the anti HIV activity tends to be stronger with the increase of the number of reducing electrons. Of them the four electron heteropoly blue of glycine containing dodecatungstogermanate (HPBG 110) has a high therapeusis index (TI).
     在MT 4细胞内 ,对合成化合物进行了抗艾滋病毒(HIV 1)活性及毒性测定 ,发现该类化合物的抗艾滋病毒 (HIV 1)活性随着还原电子数增多有增强的趋势 ,其中含有甘氨酸的十二钨锗酸 4电子杂多蓝 (代号HPBG 110 )有较高的治疗指数 (TI) .
短句来源
     The clinical medication and recent advances of anti HIV drugs have been reviewed, which include NRTIs:AZT,ddI,ddC,d4T,3TC,abacavir,tenofovir,combivir and trivizir;
     对临床应用的抗艾滋病病毒药物及进展进行了综述 ,其中包括核苷类逆转录酶抑制剂齐多夫定、去羟肌苷、扎西他滨、司坦夫定、拉米夫定、阿巴卡韦、tenofovir及 2个复合制剂双汰芝和trivizir;
短句来源
     Studies on Synthesis and Anti HIV 1 Activity of Heteropoly Complexes of Tungstotianophosphates Containing Rare Earth Elements
     钨钛磷稀土杂多酸盐的合成及其抗艾滋病病毒活性的研究
短句来源
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  抗hiv1
     The titer of anti HIV antibody and the IFN γ level in mice immunized with the pVAX1 GP120 were higher than those in mice immunized with pVAX1 respectively ( P <0.01).
     与空载体pVAX1组相比较 ,pVAX1 GP12 0免疫组小鼠血清抗HIV 1gp12 0抗体的滴度和IFN γ的水平均升高 ,两者差异显著 (P <0 .0 1)。
短句来源
     The molecular recognition of macrocyclic polyamines (MP 1,MP 2 and MP 3) to RNA, and its effects on apoptosis of cos 7 cells were studied in order to explore their mechanism of anti HIV 1 activity.
     研究了具有抗HIV 1活性的大环多胺类化合物与RNA的识别作用 ,以及其对cos 7细胞凋亡的影响 ,以进一步探讨其抗HIV 1的作用机理 .
短句来源
     The recombinant vaccinia viruses can also stimulate mice for the formation of anti HIV 1 Gag p24 antibody.
     重组病毒可诱导小鼠产生抗HIV1Gagp24抗体。
短句来源
     Aim To evaluate the therapeutic effects of anti HIV 1 integrase sFv(IN sFv) on the inhibition of HIV 1 replication.
     目的通过细胞内表达抗HIV 1整合酶单链抗体(IN sFv)基因 ,阻断病毒基因组与宿主细胞基因组的整合 ,进而抑制病毒复制 ,探讨该基因载体在HIV 1感染基因治疗中应用的意义。
短句来源
     The results of the elementary test showed that the compounds played a role in anti HIV activity by inhibiting HIV 1 absorption to the target cells surface in the early stage of virus infection.
     初步的试验结果表明 :该类化合物的抗HIV 1活性作用是在病毒感染早期 ,通过抑制艾滋病毒 (HIV 1)在靶细胞表面吸附而发挥作用的
短句来源
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  “anti hiv”译为未确定词的双语例句
     CONCLUSION Anti HIV 1 RT using HIV reverse transcriptase P 66 protein test showed that c ompounds 11, 14, 10 and 13 possessed inhibitory effects against HIV 1 reverse transcriptase (RT ), with IC 50 29 80, 35 20, 43 77 and 63 76 μmol·L -1 , respe ctively.
     结论 经HIV逆转录酶P 6 6蛋白测定 ,化合物 11,14 ,10和 13有一定抑制HIV1 RT活性 ,其IC50 分别为 2 9 80 ,35 2 0 ,4 3 77和 6 3 76 μmol·L-1。
短句来源
     Genotyping of HIV 1 in Anti HIV 1 Sero Positive Plasma
     HIV-1抗体阳性血浆中HIV-1病毒基因分型研究
短句来源
     Experimental Study on Anti HIV and Other Viruses by GO889,an Extract of Bulbus Allii
     大蒜GO889对HIV等病毒作用的实验研究
短句来源
     Antitumor and anti HIV activity of the cryptate lanthanide polyoxoanion [TbAs 4W 40 O 140 ] 25- and [PrSb 9W 21 O 86 ] 16- were reported.
     报道了以 [TbAs4 W4 0 O14 0 ]2 5- 及 [PrSb9W2 1O86]16- 为代表的穴状稀土杂多阴离子的体外、体内抗肿瘤活性及体内抗RauscherMuLV和LP BM5MuLV病毒活性。
短句来源
     AIM: To study the inhibitory effect of MAP30 (momordica anti HIV protein of 30 ku) on hepatitis B virus (HBV) replication in vitro .
     目的 :探讨MAP30 (momordicaanti HIV proteinof30ku)体外抗乙型肝炎病毒 (HBV)的作用 .
短句来源
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  anti hiv
Anti HIV-1 sera showed neutralizing activity against heterologous and even autologous escape virus.
      
HIV-1 infection of in vitro cultured human monocytes: early events and influence of anti HIV-1 antibodies
      
This method can also be used for discovery of novel anti HIV-1 drugs.
      
After intravenous injection of a low dose (25 μg/kg) in rats, the anti HIV-1 compound succinylated human serum albumin (Suc-HSA) is taken up mainly in the liver and spleen and is proteolytically degraded.
      
Pentosan polysulfate, a potent anti HIV and anti tumor agent, inhibits protein serine/threonine and tyrosine kinases
      
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In order to investigate the potential danger of HIV transmission byhuman blood γ-globulin, 3934 sera (including 614 recipients of imported γ-globulin and 40 recipients of domestic γ-globulin) from high risk populationsof AIDS were collected randomly, 6 batches of imported γ-globulin and 4batches of domestic γ-globulin.Specimens were detected by Immunofluoresce-nce Assay and Western Blot for anti-HIV. The results showed that all serawere anti-HIV negative. But, six of Ten batches...

In order to investigate the potential danger of HIV transmission byhuman blood γ-globulin, 3934 sera (including 614 recipients of imported γ-globulin and 40 recipients of domestic γ-globulin) from high risk populationsof AIDS were collected randomly, 6 batches of imported γ-globulin and 4batches of domestic γ-globulin.Specimens were detected by Immunofluoresce-nce Assay and Western Blot for anti-HIV. The results showed that all serawere anti-HIV negative. But, six of Ten batches of γ-globulin were positive.

为探讨通过人血丙种球蛋白(r-Globulin,丙球)传播艾滋病毒(HIV)的潜在危险,我们随机收集艾滋病(AIDS)高危人群血清3934份(其中包括注射进口丙球者血清614份,注射国产丙球者40份)和进口丙球6批,国产丙球4批。用免疫荧光、蛋白印迹等方法检测血清和丙球中HIV抗体。结果3934份血清HIV抗体全阴性,10批丙球中,6批HIV抗体阳性。

Blood and blood products are very important agents of HIV transmission. In this paper, 11251 samples from 10422 donors' sera and 150 blood products were screened for anti-HIV by ELISA, PA, IF and WB. The results were all negative.The donors lived in the 10 municipalities and counties of Sichuan Province. We also performed a prospective investigation to learn if these four methods were suitable to different blood products. We found that positive or weak positive reactions of ten occurred when...

Blood and blood products are very important agents of HIV transmission. In this paper, 11251 samples from 10422 donors' sera and 150 blood products were screened for anti-HIV by ELISA, PA, IF and WB. The results were all negative.The donors lived in the 10 municipalities and counties of Sichuan Province. We also performed a prospective investigation to learn if these four methods were suitable to different blood products. We found that positive or weak positive reactions of ten occurred when γglobulins were detected by IF and ELISA, but the results were negative when γ-globulins were tested by PA and WB. As a screening assay for anti-HIV, PA is most suitable for γ-globulin. WB assay is the optimal method for anti-HIV testing in terms of both specificity and sensitivity. However, because the necessary reagents are very expensive and the procedure is time-consuming, we suggest that the WB assay May be used as a confirmatory test for anti-HIV assay in countries and regions where its general use is cost-prohibitive.

输血是HIV传播的重要途径。本文报道对四川省十市县10422名献血员的11251份血清标本和各种血液制品150批进行了HIV抗体检测,结果均为阴性。对各种血液制品进行了4种HIV抗体试验方法的优选,表明检测丙种球蛋白用ELISA法和免疫荧光法易出现假阳性,建议对丙种球蛋白选用明胶颗粒凝集等法作初筛。蛋白印迹法是公认检测HIV抗体的最灵敏与最特异的方法,但操作费时及试剂昂贵,宜选作确证试验。

Equine infectious anemia virus ( EIAV ) is a retrovirus belonging to the lantivirus group.It is closely related to the human immunodeficiency virus ( HIV-1 ) .Attenuated EIAV has been adapted to growth in donkey embryonic lung cell line ( DELDC ) .This virus can be easily detected by biotin-avidin labelled EIAV antibody and by BA-ELISA methods in cell culture.EIAV reverse transcriptase ( RT ) in high titer can be extracted from infected DELDC cultures. Because EIAV is not infectious to human being, we...

Equine infectious anemia virus ( EIAV ) is a retrovirus belonging to the lantivirus group.It is closely related to the human immunodeficiency virus ( HIV-1 ) .Attenuated EIAV has been adapted to growth in donkey embryonic lung cell line ( DELDC ) .This virus can be easily detected by biotin-avidin labelled EIAV antibody and by BA-ELISA methods in cell culture.EIAV reverse transcriptase ( RT ) in high titer can be extracted from infected DELDC cultures. Because EIAV is not infectious to human being, we used EIAV as a model for screening anti HIV agents in vitro. The following anti-HIV agents: azidodeoxythymi dine ( AZT ) , foscanet ( PFA ) ,ribavirin ( RBV ) and suramine were tested in EIAV RT and DELDC culture system for their anti-EIAV activities. The results showed that: AZT,PFA, ribavirin and suramine inhibited EIAV antigen expression in cell culture; PFA, suramine and AZ TTP inhibited EIAV-RT in vitro. Twelve extracts of Chinese medicines were tested for inhibitory activity against EIAV RT,the extract of Xiao chai hu tang was found to be active. The extract of Xiao chai hu tang was also found to inhibit HIV RT and both EIAV and HIV antigen expression in cell culture.The similarity of activities of anti-HIV agents on EIAV and HIV suggest that EIAV might be useful as a model for screening anti-HIV agents.

用马传染性贫血病毒—驴胚肺二倍体细胞(EIAV-DELDC)为实验体系,以细胞中病毒逆转录酶活性及病毒相关抗原的表达为观察指标,检测了叠氮胸苷(AZT)、三氮唑核苷(Ribavirin,病毒唑)、磷羧基甲酸钠(PFA)和苏拉明等4种已知抗人免疫缺陷病毒(HIV-1)药物对马传染性贫血病毒的抑制作用。结果表明,PFA、AZTTP(三磷酸AZT)和苏拉明均能抑制病毒相关抗原的表达,AZT虽无此作用,但能抑制细胞内逆转录酶活性。用~3H-TMP掺入法比较了PFA、AZTTP、苏拉明对体外无细胞系EIAV逆转录酶粗提物和HIV-1基因工程产物逆转录酶活性的抑制作用表明,两种逆转录酶对苏拉明的敏感性相近,而HIV-1逆转录酶对PFA和AZTTP的敏感性较EIAV者高约100倍。又以无细胞系中逆转录酶活性测定法,检测了12种中药提取物的抑制作用,其中小柴胡汤对EIAV和HIV-1逆转录酶活性都有抑制作用,IC_(50)为717μg/ml和700μg/ml(生药浓度)。小柴胡汤对两种病毒感染细胞中抗原的表达和HIV引起细胞病变都有抑制作用,对HIV-1的抑制比EIAV强。这些结果表明,EIAV-DELDC体系可考虑作为抗H...

用马传染性贫血病毒—驴胚肺二倍体细胞(EIAV-DELDC)为实验体系,以细胞中病毒逆转录酶活性及病毒相关抗原的表达为观察指标,检测了叠氮胸苷(AZT)、三氮唑核苷(Ribavirin,病毒唑)、磷羧基甲酸钠(PFA)和苏拉明等4种已知抗人免疫缺陷病毒(HIV-1)药物对马传染性贫血病毒的抑制作用。结果表明,PFA、AZTTP(三磷酸AZT)和苏拉明均能抑制病毒相关抗原的表达,AZT虽无此作用,但能抑制细胞内逆转录酶活性。用~3H-TMP掺入法比较了PFA、AZTTP、苏拉明对体外无细胞系EIAV逆转录酶粗提物和HIV-1基因工程产物逆转录酶活性的抑制作用表明,两种逆转录酶对苏拉明的敏感性相近,而HIV-1逆转录酶对PFA和AZTTP的敏感性较EIAV者高约100倍。又以无细胞系中逆转录酶活性测定法,检测了12种中药提取物的抑制作用,其中小柴胡汤对EIAV和HIV-1逆转录酶活性都有抑制作用,IC_(50)为717μg/ml和700μg/ml(生药浓度)。小柴胡汤对两种病毒感染细胞中抗原的表达和HIV引起细胞病变都有抑制作用,对HIV-1的抑制比EIAV强。这些结果表明,EIAV-DELDC体系可考虑作为抗HIV-1药物筛选模型。

 
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