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   p 53 genes 在 基础医学 分类中 的翻译结果: 查询用时:1.978秒
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  “p 53 genes”译为未确定词的双语例句
    The four RV P gene nucleotide homology was 83.6%-99.8%,the amino acid homology was 87.2%-99%; the sequence interacting! with LC8 was located on 143-148 amino acids remnant bases and was DKSTQT.
    四株病毒P基因核苷酸和氨基酸序列同源性分别为83.6%~99.8%和87.2%~99%,P蛋白与胞浆动力蛋白轻链LC8相互作用的序列位于143~148位氨基酸残基,均为DKSTQT,四株病毒P基因与L蛋白、N蛋白作用位点序列显示未发生影响其生物学功能的变异。
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    High polymorphism at the human P gene locus in Chinese Han and Tibetan populations
    P基因在中国汉族及藏族群体中的多态性研究
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    Detection of polymorphism of hepatitis B virus P gene by DNA microarray
    基因芯片检测HBV DNA聚合酶区基因多态性
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    Significance of the YMDD motif mutation of P gene of hepatitis B virus
    乙型肝炎病毒P基因YMDD变异的意义
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    The Construction of Recombination Baculovirus Expression Vector of Hantavirus H8205's G1P Gene Fragment and Its Expression
    汉坦病毒H8205株G1P基因片段重组杆状病毒表达载体的构建及表达
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  p genes
The objective was to relate the response of the HSP70 and P53 genes to the cessation and the recovery of cardiac muscle cell functions when submitted to ischemia-reperfusion.
      
Comparative study of the expression Rb and p53 genes in human colorectal cancers, color carcinoma cell lines and synchronized hu
      
Comparative study of the expression of Rb and p53 genes in human colorectal cancers, colon carcinoma cell lines and synchronized
      
Concurrent abnormal expression of ERBB-2, EGFR, and p53 genes and clinical disease progression of breast carcinoma
      
These p53 genes were individually mutated at amino acid residues 143, 175, 248 and 273.
      
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Based on the previous studies with the antisense RNA techique that the inhibitory effect on HBV gene expression came from the 5'-end and non-coding region of the P gene, a hammerhead ribozyme (RCP) was synthesized according to the ribozyme structural model published by Haseliff and Gerlach. This ribozyme targeted at the 5'-end of the P gene at 2360 site (GUC) on HBV ayw genome. It was found that RCP successfully cleaved its target RNA (340 nucleotide nt) and produced 2 specific degradation...

Based on the previous studies with the antisense RNA techique that the inhibitory effect on HBV gene expression came from the 5'-end and non-coding region of the P gene, a hammerhead ribozyme (RCP) was synthesized according to the ribozyme structural model published by Haseliff and Gerlach. This ribozyme targeted at the 5'-end of the P gene at 2360 site (GUC) on HBV ayw genome. It was found that RCP successfully cleaved its target RNA (340 nucleotide nt) and produced 2 specific degradation fragments. This finding provides a basis for the further study of its blocking effect on HBV gene expression and replication in vivo.

Effectsofhammerheadribozyme(RCP)onHBVPgeneinvitroGanLixia(甘立霞),WangPing(王平),ZhuXihua(朱锡华),DongYanlin(董燕麟),HouYunde(侯云德)(Depar...

Objective:To set up a rapid detection method to detect the blood type ABO genes.Methods:The specific primer was developed according to the differences existing at several different loci in blood type ABO genes,the PCR SSP technique was used to amplify the A,B and O genes specifically.The technique had been used to analyse the polymorphism of blood type ABO genotypes in 240 blood donors.Results:p gene,q gene and r gene frequency was 0 2292,0.2125 and 0.5683,respectively.Conclusion:The...

Objective:To set up a rapid detection method to detect the blood type ABO genes.Methods:The specific primer was developed according to the differences existing at several different loci in blood type ABO genes,the PCR SSP technique was used to amplify the A,B and O genes specifically.The technique had been used to analyse the polymorphism of blood type ABO genotypes in 240 blood donors.Results:p gene,q gene and r gene frequency was 0 2292,0.2125 and 0.5683,respectively.Conclusion:The method was a simple and repid detection one that could detect the following six genotypes of blood type ABO:AB,AA,AO,BB,BO and OO.

目的:建立一种快速ABO血型基因检测的方法。方法:通过ABO血型基因中几个不同位点的差异设计出特异性引物,采用PCR-SSP技术特异性地扩增A、B、O基因,以此对240名献血者进行了ABO血型的基因型多态性分析。结果:p基因频率0.2292,q基因频率0.2125,r基因频率0.5683。结论:该方法简单、快速,可鉴定出6种ABO血型基因型AB、AA、AO、BB、BO、OO。

Objective To get information about phosphoprotein (P) genes of RSV field strains isolated in China. Methods The complete nucleotide sequences of the P protein genes from six respiratory syncytial virus strains were determined with cDNA clones which had been amplified by RT PCR and cloned into PTZ18R plasmid vector and compared with those of previously published counterparts of A2 and CH18537 strains. Results The data indicated that there had high identities (>95%) at nucleotide and...

Objective To get information about phosphoprotein (P) genes of RSV field strains isolated in China. Methods The complete nucleotide sequences of the P protein genes from six respiratory syncytial virus strains were determined with cDNA clones which had been amplified by RT PCR and cloned into PTZ18R plasmid vector and compared with those of previously published counterparts of A2 and CH18537 strains. Results The data indicated that there had high identities (>95%) at nucleotide and amino acid levels among the strains within the same subgroup; there were more divergence among strains (<85%) from different subgroups at nucleotide and amino acid levels of P genes,especially in the 3′ noncoding regions and the divergent domains. The analysis of hydrophobility indicated that there had difference from 50 to 100 amino acid of P proteins between A and B subtypes. Conclusion The analysis of the P genes confirm that there existed variability among RSV field strains and strains A2 and CH18537. The data described above revealed the characteristics of the P genes of RSV field strains isolated in China.

目的 了解我国呼吸道合胞病毒 (RSV)地方株的P(Phosphoprotein ,P)蛋白基因状况和变异特征。方法 选取不同地区具有不同流行特征的 6株RSV地方株 ,以提取的病毒mRNA为模板进行逆转录 聚合酶链扩增 (RT PCR)扩增、目的基因的克隆及序列测定分析。结果 地方株和同亚型原型株之间P蛋白核苷酸序列及推导出的氨基酸序列同源性均超过 95 % ;不同亚型间存在较大差异 ,核苷酸全序列同源性低于 85 % ,尤其在 3′端非编码区及中间变异区。由氨基酸序列推导出的疏水性分析图显示 ,A、B亚型中间变异区存在疏水性的不同 ,这为解释A、B亚型间P蛋白电泳迁移率的不同提供了一种可能。结论 我国RSV地方株与原型株之间的P蛋白无论在核苷酸水平还是在氨基酸水平均存在一定的变异。这些结果对于了解我国RSV地方株的基因状况提供了有益的资料

 
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