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high risk     
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  高危
     Quantitative Study of Multiple Biomarkers and Its High Risk Cut Off Value and Fuzzy Discrimination in Microcosmic Dialectic Type Gastric Dysplassia
     胃粘膜异型增生微观辨证分型多项生物标志变化与高危界值探讨及癌变概率模糊判别研究
短句来源
     Experimental Study on Pathogenesis of High Risk Factors Related with Hepatotoxicity of Valproic Acid and Its Prevention
     丙戊酸肝毒性高危因素作用机理及其防治的实验研究
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     Molecular Epidemiologic Studies on High Risk Human Papillomavirus in Cervical Cancer Isolated from Sichuan
     四川地区宫颈癌患者组织中高危型人乳头瘤病毒的分子流行病学研究
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     High Risk Factors in Endometriosis a Case-Control Study
     子宫内膜异位症发病高危因素的病例—对照研究
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     High Risk Factors in Epithelial Ovarian Cancer, a Case-Control Study
     上皮性卵巢癌发病高危因素的病例—对照研究
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  高风险
     SY1291-gr/gr-DAZ3/DAZ4 deletion may be affect slightly men spermatogenesis and exist as a kind of genomic polymorphism. SY1291-gr/gr-DAZ1/DAZ2 and SY1191-b2/b3-DAZ3/DAZ4 deletion are the high risk factor to male infertility,The deletion of b2/b4 is the cause which would result men's novel spermatogenic failure.
     SY1291-gr/gr-DAZ3/DAZ4缺失可能对生精功能的影响较小,仅是一种基因组多态,SY1291-gr/gr-DAZ1/DAZ2和SY1191-b2/b3-DAZ3/DAZ4缺失是男性生精障碍的高风险因子,b2/b4重组缺失是男性生精障碍的病因。
短句来源
     Methods:We collected genomic DNA respectively from 46 case venous blood(including 16 clinically diagnosed Down syndrome patients and 30 normal controls) and 40 case amniotic fluid because of high risk in prenatal screening,then used FQ-PCR method to amplify gene D21S11,S100β(in chromosome 21) and UFD1L(in chromosome 22).
     方法分别提取46例外周血(包括16例确诊为Down综合征患儿和30例正常对照)和40例唐氏筛查高风险羊水细胞基因组DNA,FQ-PCR方法扩增基因D21S11、S100β(位于21号染色体)及基因UFD1L(位于22号染色体)。
短句来源
     There was significant difference in rate of abnormal outcome of pregnant women and fetuses in the two groups(high risk and low risk of Down's syndrome groups)(26.1% and 10.5% respectively,P<0.05).
     唐氏筛查高风险度组和低风险度组的妊娠不良结局分别为26.1%和10.5%,差异有显著性(P<0.05)。
短句来源
     Conclusion: Our results showed that there are higher frenquency of gr/gr and DAZ1/DAZ2 gene copy doublets deletions in men with novel spermatogenic impairment. This indicate that gr/gr deletion and DAZ1/DAZ2 gene copy doublets deletion is a high risk factor to male infertility.
     结论在原发性男性生精障碍患者中存在较高频率的gr/gr缺失及DAZ1/DAZ2基因共缺失,提示gr/gr缺失及DAZ1/DAZ2基因拷贝的共缺失是男性不育的高风险因子。
短句来源
     [Conclusion] The findings of present study suggested that the entire DAZ deletion is a frequent genetic cause of azoospermia, and DAZ1/DAZ2 deletion is a high risk factor for the disease
     结论DAZ基因的全部缺失是无精症的遗传病因之一,而DAZ1/DAZ2缺失是无精症的一个高风险因子。
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  高危险性
     High risk of tsunami in the northern Caribbean
     加勒比海北部地区的海啸高危险性
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     The PI may be a useful clinical tool for evaluating the prognosis of patients and identifying the population with“high risk”of recurrence and death in IBC.
     PI可能是临床评价病人预后、识别IBC术后复发的高危险性病人很有实用价值的指标。
短句来源
     Cashew nut allergy is associated with a high risk of anaphylaxis
     腰果过敏与过敏反应的高危险性相关
短句来源
     2.Those who have positive anti-CCP may run a high risk in developing i nto RA.
     (2)抗CCP抗体阳性者有发展为RA的高危险性
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     A multicenter,randomized,controlled trial of lucinactant versus poractant alfa among very premature infants at high risk for respiratory distress syndrome
     多中心随机对照研究lucinactant和poractant alfa对过早产儿高危险性呼吸窘迫综合征的作用
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  高危险
     The H-FABP-positive rate was 94.7% and the negative rate was 5.2% in the group of high risk stratification at 30 days(P<0.001).
     高危险组H-FABP阳性率94.7%,阴性率5.2%(P<0.001)。
短句来源
     Analysis on Efficacy of Low Molecular Weight Heparin on 73 Cases of Middle and High Risk Unstable Angina
     低分子肝素治疗不稳定型心绞痛中、高危险组73例疗效分析
短句来源
     For the high risk workers,the time elapsed for the occurrence of clinical cancer was 18 months in average and the average patent time of occupational bladder cancer was 21.2 years (5~30 years).
     高危险度者发展到临床确诊平均历时 18个月。 职业性膀胱癌发病潜伏期 5~ 30年 ,平均 2 1.2年。
短句来源
     Methods According to the history, electrocardiogram changes and serum levels of troponin T(TnT),one hundred and fifteen patients with UA were classified into three groups: low risk(group A, n =48), intermediate risk(group B, n =36) and high risk(group C, n =31).
     方法  115例 U A患者根据其病史、心电图及肌钙蛋白 T(Tn T)变化分为低危险组 (A组 ,48例 )、中危险组 (B组 ,3 6例 )和高危险组 (C组 ,3 1例 )。
短句来源
     It expatiated the research progress on nursing care of senile acute coronary syndrome patients from aspects of quickly evaluation,right away handling,and effective intervention on high risk acute coronary syndrome patients,paying attention to observe atypical symptoms of them,complication prevention,observation on drug efficacy and adverse reaction,nursing care of thrombolysis therapy and coronary artery intervention therapy.
     从迅速评估、快速处理和有效干预高危险度的急性冠脉综合征,重视不典型症状的观察,预防并发症的发生,观察药效及副反应,溶栓的护理,心脏介入术的护理方面阐述了急性冠脉综合征的护理研究进展。
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  high risk
High risk factors for pulmonary fungous infection in intensive care units of neurosurgery
      
By analyzing the high risk factors for pulmonary fungous infection in intensive care units of neurosurgery, the strategy of early diagnosis and treatment was explored.
      
To eliminate these high risk factors, early diagnosis and the use of prophylactic antifungal agents can help reduce the incidence of pulmonary fungous infection.
      
The COX hazard proportional model revealed that advanced clinical stage (P = 0.001), large tumor size (P = 0.001), a high mitotic index (P = 0.002) and the high risk grade (P = 0.018) indicated a poorer prognosis in gastric GIST.
      
Expression of the STAT1 gene belonging to the group of interferon-regulated genes was analyzed in cervical tumors and cell lines harboring the genome of human papilloma viruses (HPV) of so-called high risk group.
      
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Studies on 5,500 metaphase plates from 103 members of 5 high risk cancer families and 1,567 metaphase plates from 30 members of 4 low risk cancer families were carried out. The investigated individuals of both groups lived in close proximity. Although the modal number and Karyotype were normal diploid (2n = 46), many more cells from members of high cancer families were found to show aneuploid and various types of structural aberrations than those from members of low risk families. In...

Studies on 5,500 metaphase plates from 103 members of 5 high risk cancer families and 1,567 metaphase plates from 30 members of 4 low risk cancer families were carried out. The investigated individuals of both groups lived in close proximity. Although the modal number and Karyotype were normal diploid (2n = 46), many more cells from members of high cancer families were found to show aneuploid and various types of structural aberrations than those from members of low risk families. In the high risk group, 1.6% of the cells showed numerical aberrations and 3.25% structural aberrations, while the corresponding figurs for the low risk group were 0.5% and 0.72% respectively (p < 0.01). The 101 chromatid breaks found in the high risk cancer families were mostly distributed among chromosomes of A, B and C groups and occurred more frequently in long arms (q) than in short arms (p). During karyo-typing it was found that chromosomes A2 could not be matched with each other in 10 cells out of 300. The interaction between genetic and environmental factors in the carcinogenesis of esophageal cancer in Linxian County was briefly discussed.

从林县5个食管癌高癌家族成员103名及与之毗邻的4个低癌家族成员31名的淋巴细胞所作的染色体对比分析结果表明:高癌和低癌家族成员淋巴细胞染色体众数及其核型均属正常二倍体(2n=46)。但在高癌组中查到1.6%和3.25%具有染色体数目和结构异常的细胞,与低癌组比较有非常显著的差别(P<0.01)。核型分析发现有少数假二倍体、G组三体性和第2号染色体不配对现象。101个染色单体断裂主要集中在A、B、C三组,断裂部位长臂比短臂为多。对肿瘤发生中遗传和环境(内因和外因)因素的相互作用进行了讨论。

Our previous works showed that carcinogenic N-nitroso compounds can be formed in food contaminated by fungi. In the present study it was demonstrated that some common species of fungi encountered in Linxian County, a high risk area for esophageal cancer in Henan Province, would not only reduce nitrates to nitrites but also increase the amount of secondary amines in tainted cornbread, and promote the synthesis of nitrosamines from these precursors in food. Species such as Fusarium moniliforme, Aspergillus...

Our previous works showed that carcinogenic N-nitroso compounds can be formed in food contaminated by fungi. In the present study it was demonstrated that some common species of fungi encountered in Linxian County, a high risk area for esophageal cancer in Henan Province, would not only reduce nitrates to nitrites but also increase the amount of secondary amines in tainted cornbread, and promote the synthesis of nitrosamines from these precursors in food. Species such as Fusarium moniliforme, Aspergillus versicolor and Geotrichum candidum had a greater ability to reduce nitrates than Penicillium brevi-compactum, P. lividum, Aspergillus niger and A. sydowii. A 17-fold increase in secondary amines occurred in cornbread inoculated with F. monili-forme after 6-day incubation. Moreover,G. candidum and other fungi modified the acidity of mouldy food and provided favorable conditions for the synthesis of nitrosamines. Thus the experimental results gave further evidences for the important role played by certain fungi in the production of chemical carcino gens.

我们首次发现在霉变食物中有亚硝胺类致癌物的形成[1~3]。进一步研究证明食管癌高发区林县常见的真菌,如串珠镰孢霉、白地霉等,不但能还原食物中的硝酸盐为亚硝酸盐,而且能增加其二级胺的含量,并促进这些前体物合成亚硝胺。这表明某些真菌除能产生真菌毒素外,在霉变食物中能形成其它化学致癌物,因此在癌症病因中起重要作用。

A primary epidemiologic survey about causative factors of esophageal carcinoma was carried out among "Hasakezu" in Xinyuan District, Xinjian Province and a comparison made in Jinghe District between "Hasakezu" , "Mengguzu" and"Weiwuerzu".Results suggested that cheese(fresh or mol- dy), moldy meat and smoking"Mahe"were of relatively high risk and there was a similarity between statistics from both districts. So it was possible that moldy, food be an important factor in the formation of esophageal carcinoma....

A primary epidemiologic survey about causative factors of esophageal carcinoma was carried out among "Hasakezu" in Xinyuan District, Xinjian Province and a comparison made in Jinghe District between "Hasakezu" , "Mengguzu" and"Weiwuerzu".Results suggested that cheese(fresh or mol- dy), moldy meat and smoking"Mahe"were of relatively high risk and there was a similarity between statistics from both districts. So it was possible that moldy, food be an important factor in the formation of esophageal carcinoma. No apparent relation to carcinoma formation was found among other doubtful factors, such as wine, tea, "Nas" , sour milk and horse milk etc.

本文报告作者对新疆地区新源县食管癌高发的哈萨克族进行了病例对照调查;对精河县的哈萨克族、蒙古族、维吾尔族进行了流行因素的比较调查。结果发现奶渣、发霉奶渣、发霉熏肉、吸烟对食管癌的发生均有较高的危险度。两县调查的结果有一致性,显示了发酵霉变食物可能是食管癌的重要流行因素。其它一些可疑致癌因素如酒、茶、纳斯、酸奶、马奶、家族史等,未显示它与食管癌的发生有联系。

 
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