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     Adiponectin and Coronary Atherosclerosis
     脂联素与冠状动脉粥样硬化的研究现状
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     Coronary Artery Calcification
     冠状动脉钙化研究进展
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These proteins may be involved in cardiovascular injury, and could play an important role in the treatment of coronary heart disease.
      
Evaluation of the effect of myocardial perfusion after percutaneous coronary intervention in coronary artery disease by using in
      
Detection of abnormal myocardial perfusion is crucial to the prognosis of patients with coronary artery disease (CAD) after they have undergone percutaneous coronary intervention (PCI).
      
No difference was found in CTFC between the coronary artery stenosis group and the normal group.
      
Thus, the IC-MCE method is of great value to coronary artery disease (CAD) patients undergoing PCI, especially for those with acute myocardial infarction (AMI).
      
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Observations on the coronary arteries of 100 embalmed and 20 fresh hearts of Chinese children were made. The results were as follows: 1. The point of origin of the coronary arteries was found horizontally at the middle third of the aortic sinus in 90.5%, and vertically below the upper margin of the aortic sinus in 91.5%. The diameter of the opening of the left coronary artery was greater than that of the right side in 77%' lesser than that of the right side in 4%, and equivalent to that of...

Observations on the coronary arteries of 100 embalmed and 20 fresh hearts of Chinese children were made. The results were as follows: 1. The point of origin of the coronary arteries was found horizontally at the middle third of the aortic sinus in 90.5%, and vertically below the upper margin of the aortic sinus in 91.5%. The diameter of the opening of the left coronary artery was greater than that of the right side in 77%' lesser than that of the right side in 4%, and equivalent to that of the right side in 19%. 2. The accessory coronary arteries occurred in 47% of the cases, and all were found on the right side. In one case, an accessory coronary artery distributed to the anterior wail of the right atrium. 3. Type II, i.e. the posterior wall of the left ventricle which was mainly supplied by the right circumflex branch, was the most common type of distribution. It occurred in 59%. 4. The interventricular septum was supplied by both the anterior and posterior descending branches, the proportion of which is determined by the length of the two descending branches. 5. The left coronary artery divided into 3 main branches (anterior descending, diagonal, left circumflex) in 56%. 6. Ramus septi fibrosi which originated from the right circumflex was found in 97% and from the left circumflex in 3%. 7. Ramus ostii cavae superioris was a constant branch, originating from the right side in 64% and from the left side in 36%. 8. The difference in number of the blood vessels to the left and right ventricles was not obvious.

用防腐了的100個中國兒童心臟,20個新鮮心臟,對心臟冠狀動脈的分佈類型作了觀察,其結果如下: 1.冠狀動脈的起點在横的位置以主動脈竇的中央爲最多,佔90.5%,縱的位置是在主動脈竇和主動脈分界綫以下的最多,佔91.5%。左冠狀動脈口的口徑大於右側的是77%,小於右側的4%,左右相等的19%。 2.副冠狀動脈的出現有47%,全部在右側,其中1例副冠狀動脈分佈右心房前壁。 3.在中國兒童冠狀動脈的分枝類型型II佔59%,也就是說左室後壁主要是由右旋枝分佈的較多。 4。前、後降枝分佈室中隔的範圍和兩個降枝的長短成正比例。 5.左冠狀動脈分爲三個主幹(前降枝,斜角枝,左旋枝)的佔56%。 6.縱隔纖維枝有97%來自右旋枝,3%球來自左旋枝。 7.上腔靜脈口枝是心房的一個固定枝,起於右側冠狀動脈的64%,左側的36%。 8.左右冠狀動脈的分枝之間經常存在着吻合。 9.左右心室的血液供給沒有顯明量的差別,只是在動脈口徑上稍有不同。

Coronary blood flow was measured by bubble flow meter in 11 dogs anesthetized with chloralose.The blood pressure,coronary blood flow,and coronary vascular resistance were found to be(mean±s.d.):83±13 mm Hg,80±14 ml/100g myocardium/minute,and 1.06±0.28 mm Hg/(ml/100 g

气泡流量计法测定麻醉狗冠脉血流量。给药前11只狗血压、冠脉血流量及冠状血管阻力的平均数±标准差分别为:83±13毫米汞柱,80±14毫升/100克心肌/分及1.06±0.28毫米汞柱/(毫升/100克心肌/分)。静脉注射萝芙木根总硷0.2毫克/公斤后,血压降低了原水平的30—40%,对冠脉血流无明显影响,而冠脉阻力则显著降低。冠状动脉内注射0.1毫米未引起变化。因此认为萝芙木根总硷能使冠状动脉扩张,对高血压病人冠状循环机能不全情观可能有益。

Coronary blood flow was measured by N_2O desaturation method in anesthetized dogs. Coronary sinus catheterization was made under fluoroscopic guidance. Myocardial consumptions of oxygen, glucose, lactic acid and pyruvic acid were calculated from the differences between arterial and coronary sinus blood concentrations. This study was designed in paired experiments, and the results were analyzed by t test of individual comparisons. Normal values (mean±s.d.) of 9 dogs were: 143±17 and 8±3 mm Hg for arterial...

Coronary blood flow was measured by N_2O desaturation method in anesthetized dogs. Coronary sinus catheterization was made under fluoroscopic guidance. Myocardial consumptions of oxygen, glucose, lactic acid and pyruvic acid were calculated from the differences between arterial and coronary sinus blood concentrations. This study was designed in paired experiments, and the results were analyzed by t test of individual comparisons. Normal values (mean±s.d.) of 9 dogs were: 143±17 and 8±3 mm Hg for arterial and coronary sinus pressures, 88±21 ml/100 g myocardium/min for coronary blood flow, 1.7±0.4 mm Hg/ml/100 g myocardium/min for coronary vascular resistance, 18.1±1.9 and 5.6±1.1 vol % for arterial and coronary sinus oxygen contents, 116±24 and 109±20 mg% for arterial and coronary sinus glucose, 24±7 and 16±5 mg % for arterial and coronary sinus lactic acid, and 1.7±0.5 and 0.8±0.3 mg % for arterial and coronary sinus pyruvic acid, respectively. The total alkaloids of the root of R. verticillata were injected i.v. 0.1 mg/kg. The arterial blood pressure was lowered about 25% and restored after 1/2 hour. There was no remarkable alteration in coronary blood flow, but the coronary vascular resistance tended to decrease, which inferred that the coronary vessels had an inclination to dilate. The myocardial consumptions of oxygen, lactic acid and pyruvic acid were higher than that of glucose, indicating that the myocardium gained its energy mainly from the aerobic metabolism of carbohydrates. Following the injection of the alkaloids, the lactate and pyruvate levels in the arterial blood rose significantly. Since the alkaloids increased the left ventricular work but not the oxygen consumption, the mechanical efficiency of myocardium was elevated from 15% for the premedicated heart to 20%. En resume, the total alkaloids have certain effects in dilating coronary vessels, in augmenting the myocardial efficiency, and in enriching its energy supply. Hence the alkaloids exert a beneficial influence on the compensatory capacity of the hypertensive heart.

本文介紹了N_2O減飽和法測定不开胸狗冠脉血流量的方法,并研究了海南島萝芙木根总碱的作用,及其对心肌糖代謝的影响。在X光透視下經靜脉插管至冠状資,从冠状动、靜脉血N_2O減飽和速率之差,計算心肌血流量,并从动、靜脉血氧、糖、乳酸及丙酮酸合量之差,計算心肌的消耗量及利用率。实驗設計采用配对法,进行t測驗个别比較,以分析除去动物个体差异及对照溶剂的影响后萝芙木碱本身的作用。 9只狗之各項正常数值平均数±标准差为:动脉平均压143±17毫米汞柱,冠状竇平均压8±3毫米汞柱,冠脉血流量88±21毫升/100克心肌/分,冠脉阻力1.7±0.4毫米汞柱/毫升/100克心肌/分,动脉血氧合量18.1±1.9容积%,冠状竇血氧含量5.6±1.1容积96,动脉血糖116±24毫克%,冠状竇血糖109±20毫克%,动脉乳酸24±7毫克%,冠状寶乳酸16±5毫克%,动脉丙酮酸1.7±0.5毫克%,冠状竇丙酮酸0.8±0.3毫克%。 靜脉注射萝芙木碱0.1毫克/公斤后,血压立即明显下降約25%,半小时后回升,冠脉血流量变化不显著,冠脉阻力有减低趋势,說明萝芙木碱降压时并不引起冠脉血流减少,冠状血管趋于扩张。心肌对氧、乳酸和丙酮酸的利...

本文介紹了N_2O減飽和法測定不开胸狗冠脉血流量的方法,并研究了海南島萝芙木根总碱的作用,及其对心肌糖代謝的影响。在X光透視下經靜脉插管至冠状資,从冠状动、靜脉血N_2O減飽和速率之差,計算心肌血流量,并从动、靜脉血氧、糖、乳酸及丙酮酸合量之差,計算心肌的消耗量及利用率。实驗設計采用配对法,进行t測驗个别比較,以分析除去动物个体差异及对照溶剂的影响后萝芙木碱本身的作用。 9只狗之各項正常数值平均数±标准差为:动脉平均压143±17毫米汞柱,冠状竇平均压8±3毫米汞柱,冠脉血流量88±21毫升/100克心肌/分,冠脉阻力1.7±0.4毫米汞柱/毫升/100克心肌/分,动脉血氧合量18.1±1.9容积%,冠状竇血氧含量5.6±1.1容积96,动脉血糖116±24毫克%,冠状竇血糖109±20毫克%,动脉乳酸24±7毫克%,冠状寶乳酸16±5毫克%,动脉丙酮酸1.7±0.5毫克%,冠状竇丙酮酸0.8±0.3毫克%。 靜脉注射萝芙木碱0.1毫克/公斤后,血压立即明显下降約25%,半小时后回升,冠脉血流量变化不显著,冠脉阻力有减低趋势,說明萝芙木碱降压时并不引起冠脉血流减少,冠状血管趋于扩张。心肌对氧、乳酸和丙酮酸的利用率很高,而对血糖消耗很少,說明心肌主要从糖的有氧代謝获取能量。靜脉注射萝芙木碱后,动脉血的乳酸及丙酮酸含量均显著增高,因此能增加心脏的能源供应,改善心肌的营养。萝芙木碱能加強左心室作功量,而心肌氧消耗量并未增高,故計算出心肌机械作功率从15%提高到20%。总結本文結果:萝芙木碱在扩张冠状血管、提高心肌作功率及增加心肌能源供应三方面都有一定的作用,因此对高血压心脏的代偿能力的提高是有利的。

 
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