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breast tissue
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  乳腺组织
     ② Results of PCR-SSCP: The polymorphisms of two P21WAF1 gene were 24.2% (29/120) in the breast carcinoma and 6.0% (3/50) in the benign breast tissue, significantly higher in the former than in the latter (P < 0.05).
     ②聚合酶链反应单链构象多态性检测结果:120例乳腺癌和50例良性乳腺组织P21WAF1基因多态性分别为24.2%(29/120)和6.0%(3/50),乳腺癌组织高于良性乳腺组织,两组间差异有显著性(P<0.05)。
短句来源
     12 benign breast tumors and 12 normal breast tissue were 0.908±0.047、0.934±0.038 respectively.
     12例乳腺良性肿瘤及正常乳腺组织表达水平分别为0.908±0.047、0.934±0.038;
短句来源
     the expression of BRMS1mRNA in 12 patients with benign breast tumors and 12 patients with normal breast tissue was 0.908±0.047 and 0.934±0.028 respectively.
     12例乳腺良性肿瘤及正常乳腺组织表达水平分别为0.908±0.047和0.934±0.028;
短句来源
     Methods In 64 cases of IDC,15 cases of ductal carcinoma in situ(DCIS),15 cases of benign breast tissue and 15 cases of adjacent normal breast tissues,the expression of p57KIP2 proteins was detected by immunohistochemical S-P methods.
     方法采用免疫组织化学S-P法检测64例IDC、15例乳腺导管内癌(ductal carcinoma in situ,DCIS)、15例乳腺良性病变和15例癌旁正常乳腺组织中p57KIP2蛋白的表达。
短句来源
     . esults The positive rate for c-erbB-2 expression in breast cancer(59.2%)were higher than in benign breast diseases(3.9%)and in normal breast tissue(0%)(x2=27.06,P<0. 01;X2=12. 78,P<0.01,respectively).
     结果乳腺癌C-erbB-2阳性率(59.2%)明显高于乳腺良性病变(3.9%)和正常乳腺组织(0%)(X2=27.06,P<0.01,X2=12.78,P<0.01)。
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  乳腺标本
     Methods: The expression of Muc1 and C-erbB-2、ER、PR、E-cadherin were examined by immunohistochemistry in 5 specimens of normal breast tissue, 5 specimens of breast fibroadenomas and 40 specimens of primary breast cancer.
     方法:应用免疫组织化学SP法检测5例正常乳腺标本、5例乳腺纤维腺瘤标本,40例乳腺癌组织标本的原发灶中Muc1、C-erbB-2、ER、PR及E-cadherin的表达情况。
短句来源
     Methods The expression of CD 44 s and CD 44 V 6 was examined in tissue microarray (TMA) which containing 120 ductal carcinomas of the breast and 20 normal breast tissue by using immunohistochemistry(IHC).
     方法 :用组织芯片技术及免疫组织化学方法检测 1 2 0例乳腺导管癌标本和 2 0例正常乳腺标本中CD44s和CD44V6表达情况。
短句来源
     [Methods] The expression of Syk, C-erbB-2 and PCNA were examined by immunohistochemistry in 5 specimens of normal breast tissue, 5 specimens of breast fibroadenomas and 35 specimens of breast cancer.
     [方法]应用免疫组化法检测5例乳腺纤维腺瘤、5例正常乳腺标本和35例乳腺癌手术标本中Syk和C-erbB-2、PCNA的表达水平。
短句来源
     [Results] In breast fibroadenomas and normal breast tissue, the C-erbB-2 and PCNA were negatively expressed in all specimens, while Syk was positively expressed in all specimens.
     [结果]正常乳腺标本及乳腺纤维腺瘤标本中C-erbB-2及PCNA均为阴性而Syk全部呈阳性。
短句来源
  “breast tissue”译为未确定词的双语例句
     Results:The positive expression rates of ER,PR and pS2 were 11.53%,15.38% and 0 in normal breast tissue;
     结果:ER、PR、pS2在26例正常对照组中阳性表达率分别为11.53%,15.38%,0;
短句来源
     There was linearity relation between expression of HO-1 and MEA in breast tissue(y=454.66+106.67x)(r=0.8476,t=2.487 3,P<0.02).
     正常乳腺、乳腺增生、乳腺纤维腺瘤到乳腺癌组织的MEA逐渐增多(P<0.01),HO-1蛋白表达与MEA存在线性相关,y=454.66+106.67x,相关系数r=0.8476(t=2.487 3,P<0.02)。
短句来源
     Results The expression of BRMS1mRNA in 71 patients with breast cancer and adjacent breast tissue was 0.378±0.046 and 0.918±0.044,respectively;
     结果在71例乳腺癌及其相应癌旁组织中BRMS1 mRNA表达水平分别为0.378±0.046和0.918±0.044;
短句来源
     Results Positive rate of VEGF-C in malignant breast tumor was 46.7%,much higher than that in normal breast tissue and benign breast tumor, which were 10.0% and13.3%, respectively.
     结果在乳腺恶性肿瘤组织中,VEGF-C阳性表达率为46.7%,明显高于正常乳腺(10.0%)和乳腺良性肿瘤组织(13.3%)(P<0.01);
短句来源
     We have got results as follows:1. We found the positive expression of ER,PR,pS2,and P53,C-erbB-2 were in order 11.53%, 15.38%, 0%, 0%, 0% in normal breast tissue;
     1、ER、PR、pS2和P53、C-erbB2在26例正常对照组中阳性表达率分别为11.53%、15.38%、0%、0%、0%;
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  breast tissue
The same method and analysis demonstrated binding of anti-BSM IgG to MUC1 and to smaller antigens of 85-120 kD in samples containing CA15-3 antigen: commercial standard preparation, human breast tissue, and human milk.
      
In this study, expression level of different proteoglycans (decorin, syndecan-1, lumican, glypican-1, and aggrecan) in tumors and normal human breast tissue was investigated.
      
For each gene, the rate of promoter methylation and changes in expression were estimated in tumor and morphologically intact paired specimens of breast tissue (N = 100).
      
The genes were not methylated in morphologically intact breast tissue.
      
Some remarkable FTlR spectral differences are observed and the differences at the molecular level are extracted between benign and malignant breast tissue samples.
      
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Three cases of carcinoma of the accessory breast are described,there being detec- table breast tissue in the lesion but no anatomic continuity with the main breast. Microscopically there are elements of intraductal carcinoma and lobular structures beside frank infiltrative carcinoma.The treatment is similar to that of the main breasts,but prognosis is relatively poor.

本文报告3例腋下副乳腺癌。临床均查见副乳腺存在,副乳腺组织与乳房无关。镜捡除乳腺癌组织外,见有腺小叶结构和管内癌成分。本病治疗同乳腺癌,预后较差。

Excision of locally thickened breast tissue was done in 98 patients during 1979-1982. Most of these patients were over 40 years of age with high risk factors for breast cancer but with no positive findings on ordinary diagnostic procedures. Of these 98 biopsied specimens, 8 (8.2%) were found to be carcinoma, 5 of these were in patients aged over 50 years of age. These findings suggest that persistent thickening of breast tissue in women over 50 years of age, especially those associated with...

Excision of locally thickened breast tissue was done in 98 patients during 1979-1982. Most of these patients were over 40 years of age with high risk factors for breast cancer but with no positive findings on ordinary diagnostic procedures. Of these 98 biopsied specimens, 8 (8.2%) were found to be carcinoma, 5 of these were in patients aged over 50 years of age. These findings suggest that persistent thickening of breast tissue in women over 50 years of age, especially those associated with high risk factors for breast cancer should be regarded with greater suspicion. Furthermore, papillomatosis considered to possess malignant potential were also found in 5 cases of this series. Therefore, excisional biopsy of locally thickened breast tissue may provide leads in tracing precancerous lesions as well as detecting early breast cancer.

1979~1982年间共对98例乳腺组织局部增厚者进行切除病检,着重40岁以上、伴有乳腺癌易感因素且经2~4项诊断方法检查无阳性发现者。在98例切检中,发现癌8例,占8.2%,2/3年龄在50岁以上,6例伴易感因素。因此认为乳腺腺体增厚出现在50岁以上,尤其伴有易感因素时,应与肿块同等重视。本组尚发现活跃增生的乳头状瘤病5例,此类病变存在有癌变的危险性,切检将为跟踪此类“癌前”病变和发现早期癌提供重要线索。

During 1954-1972, 157 patients with stage I breast cancer were treated by surgical procedures. In 31 cases the tumors were ≤1 cm in greatest diameter, and in 126 cases >1 cm-≤2 cm. Simple mastectomy was done in 4 cases. Halsted radical mastecto- my in 94, extended radical mastectomy in 14, and modified radical mastectomy in 45. 1/5 of No cases and 1/3 of N_1a cases were of positive pathology. The 5-year rate of NED* in this series was 86%, and the 10-year rate 76.3%. The 10-year NED rate of specific type of...

During 1954-1972, 157 patients with stage I breast cancer were treated by surgical procedures. In 31 cases the tumors were ≤1 cm in greatest diameter, and in 126 cases >1 cm-≤2 cm. Simple mastectomy was done in 4 cases. Halsted radical mastecto- my in 94, extended radical mastectomy in 14, and modified radical mastectomy in 45. 1/5 of No cases and 1/3 of N_1a cases were of positive pathology. The 5-year rate of NED* in this series was 86%, and the 10-year rate 76.3%. The 10-year NED rate of specific type of carcinoma (92%) was much better than non- specific type (68%) (P<0.01). A significant statistical difference in 10-year cure ra- tes of the three types of operation was not discernible, as the number of patients in each group was small. According to our experience, Certain types of stage I breast cancer, such as papi- llary cystic adenocarcinoma, typical medullary carcinoma, non-infiltrative intraductal carcinoma, lobular carcinoma in situ, Paget′s disease of the nipple without duct car- cinoma in breast tissue, and early carcinomatous change in cystic hyperplasia, simple mastectomy appears to be sufficient. In other types of breast cancer, modified radical mastectomy may be the treatment of choice.

I期乳腺癌系指T_1N_0-laMo的乳腺癌而言。我院自1954到1972年共手术治疗157例I期乳腺癌,其中~1cm者31例,1~+~2cm者126例。行单纯全乳切除术4例,Halsted根治术94例,扩大根治术14例和改良根治术45例。临床为N_0者约1/5腋淋巴结阳性,N_1a者约1/3病理阳性。157例的5年健在率86%,156例的10年健在率为76.3%。特殊型癌的10年健在率为92%,明显优于非特殊型癌的68%(P<0.01)。因本组例数较少,故三种术式的10年疗效未见明显的统计学差异。本组经验认为某些Ⅰ期乳腺癌(如乳头状囊腺癌、典型髓样癌、无管外浸润的管内癌、无乳腺实质腺癌的乳头湿疹样癌、小叶原位癌和囊性增生病早期癌变等)可仅行单纯全乳切除术,其它则宜行改良根治术。

 
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