We determined lidocaine and its primary metabolite monoethylglycinexylidide (MEGX) serum concentrations with the TDX (Abbott Laboratories) at baseline and 3,6 ,10,15,30,45, 60,90,120, 300 min after the intravenous administration of lidocaine (1 mg/kg), analyzing specimens from 8 apparently healthy volunteers and 4 patients with liver cirrhosis.
The pharmacokinetics of famotidine was studied after a single oral dose of 40mg to 6 men(age 46± s 15 a)with liver cirrhosis and 6 men(age 49± 10 a) with liver cancer. A one-compartment open model was adopted in the analysis.
In order to observe the effect of hepatocyte growth promoting factor (pHGF) on liver regeneration of rat with cirrhosis after hepatectomy, IBAS Ⅱ auto image analysis technology was used to measure the variety of DNA ploid rate of hepatocytes and OPTDM of enzymes by liver histochemistry after hepatectomy; serum levels of the glutamic pyruvic transaminase (SGPT) and indocyanine green retention rate in 15 minute (ICG 15 ) were tested to measure the function of the remanent liver.
In treating hepatocellular carcinoma (HCC) patients with advanced cirrhosis, one of the most difficult problems is concomitant esophageal varices and hypersplenism.
The surgical treatment methods for cirrhosis patients complicated with portal hypertension are complicated.
From 1979 to 2005, 274 cirrhosis patients with portal hypertension who underwent the new treatment strategy were followed up to observe different clinical indexes, which were then compared with those of the traditional surgery treatment.
Postoperative hepatic insulin-like growth factor-1 (IGF-1) production may be severely disturbed in patients with liver cirrhosis.
Twenty-four patients with HCC with cirrhosis who underwent hepatectomy were randomly divided into two groups: a PN group (n = 12) and an rhGH + PN group (n = 12).