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thrombolytic drug
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  溶栓药物
     In order to gain thrombolytic drug from microorganism,a strain named W-15 with high yield of fibrinolytic enzyme was separated from the soil and the fermented soybean.
     为从微生物中获取溶栓药物,从土壤、豆豉中获得产纤溶酶活性高的1株菌株,命名为W-15。
短句来源
     A NEW THROMBOLYTIC DRUG RETEPLASE
     新型溶栓药物瑞替普酶
短句来源
     Conclusion FSC2-13 possessed in vitro and in vivo thrombolytic activities in a special way. There seem to be prospects for researches to develope it into a new generation of oral thrombolytic drug.
     结论  FSC2 - 13具有体内外溶纤活性 ,而且方式特殊 ,有望开发成新一代的口服溶栓药物
短句来源
     Thromlysis is the basic way to recanalize blood vessels and urokinase (UK) is one of the most usual thrombolytic drug in our nation. Unfortunately, the serious risk ofcerebral hemorrhage and the very short therapeutic window of 6 even 3 hours postischemia are the important limitation to the widespread use of UK in the management of acute stroke.
     溶栓是再通血管的根本方法,尿激酶(urokinase,UK)是目前国内常用的溶栓药物,但并发脑出血的危险性及梗死后6h甚至3h的治疗时间窗限制了临床的溶栓治疗。
短句来源
     Nattokinase (NK) is a kind of fibrinolytic enzyme, which is expected to be a new thrombolytic drug.
     纳豆激酶是一种纤维蛋白溶解酶 ,有望开发成为新型的溶栓药物 .
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  溶栓药
     Thrombolytic drug infusion via carotid artery treating experimental central retinal artery occlusion
     经颈内动脉灌注溶栓药治疗实验性视网膜中央动脉阻塞
短句来源
     Our results proved that r-SK was a less toxic thrombolytic drug.
     凝血功能改变与剂量有关,并在停药14d后恢复,结果表明重组链激是一个毒性低的溶栓药
短句来源
     Objective To investigate the therapeutic effects of thrombolytic drug infusion via carotid artery on experimental central retinal artery occlusion (CRAO), and observe the changes of fibrinolytic activity in the systemic circulation.
     目的 观察经颈内动脉灌注溶栓药治疗实验性视网膜中央动脉阻塞 (CRAO)的效果及对全身的影响。
短句来源
  溶栓剂
     [Conclusion] It is suggested that the method of homemade r-sk thrombolytic therapy by vein is a safety, effective thrombolytic drug with higher repass rate.
     认为国产r-SK静脉溶栓治疗血管再通率高,是一种安全有效的溶栓剂
短句来源
     Conclusion Use r-tPA as a drugs in thrombolysis in treating AMI,was easier to occur fatal arrhythmias,but r-tPA was still the best thrombolytic drug in treating AMI.
     结论应用r-tPA溶栓治疗急性心肌梗死时容易发生恶性再灌注性心律失常,但仍是目前最好的溶栓剂
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  “thrombolytic drug”译为未确定词的双语例句
     6 12 hours following thrombolytic drug, the serum cTnI increased significantly in comparison with non thrombolytic group of AMI ( P < 0.05).
     在溶栓治疗后8~12小时,cTnI显著高于溶栓未通或未溶栓(未自溶)病人(P<0.05)。
短句来源
     Methods Totally, 108 STEMI patients were enrolled, 66 patients underwent primary PCI (PCI group), and 42 patients were treated with thrombolytic drug: urokinase therapy (UK group).
     方法108例STEMI患者,66例行直接PCI治疗(PCI组),42例行溶栓治疗(UK组)。
短句来源
     A New Thrombolytic Drug——Nattokinase
     新型溶血栓药——纳豆激酶
短句来源
     The process was Octyl-Sepharose Fast Flow, Phenyl-Sepharose HP, SP-Sepharose HP. The purified enzyme was homogeneous, as examined by SDS-PAGE and PAGE. Recently it become more popular that thrombolytic cure is significantly effective to decrease thrombus disease fatality rate and disabling rate, therefore, thrombolytic drug's research become current research focus and is more attractive.
     根据目标酶的基本性质,选择了载量大、制备速度快的疏水层析色谱及强阳离子交换色谱模式并进行合理组合,确定的目标酶色谱分离流程为Octyl-Sepharose Fast Flow、Phenyl-Sepharose HP、SP-Sepharose HP。
短句来源
     A good thrombolytic drug could dissolve not only old thrombus but also new thrombus, and lower rate of thrombus formed again.
     一个好的溶纤剂能够溶解陈旧或新鲜的血栓,再栓塞率低。
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  thrombolytic drug
Notably, while thrombolytic drug therapy treats only the acute cause, that is, thrombus, the laser has the potential for treating both thrombus and its underlying cause, that is, the atherosclerotic plaque.
      
The lysis of the occluding embolus was obtained by injection of the thrombolytic drug directly or near the thrombus without haemor-rhagic complications.
      
The possibility that a thrombolytic drug could lyse a clot which obstructed arterial flow has always been an attractive one.
      
Recombinant t-PA is at present used as a thrombolytic drug, for instance, after a myocardial infarction.
      
One explanation might be that the 4-mg dose of tPA increases the risk of delayed bleeding and may represent an excessive dose of thrombolytic drug.
      
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124 cases of acute arterial embolism involving 138 arteries (156 limbs) in the past 25 years were reported.Location of the arterial embolisms included lower abdominal aorta 20, iliac artery 17, femoral artery 31, popliteal artery 41, tibial artery 9 and upper limb artery 20.Most the patients (87.9%)were over 31 years old;92 cases were secondary to organic cardiac diseases. Embolectomy was performed in 42 limbs(41 patients).Thrombolytic drugs-urokinase and general drugs were used in 33 and 47 cases...

124 cases of acute arterial embolism involving 138 arteries (156 limbs) in the past 25 years were reported.Location of the arterial embolisms included lower abdominal aorta 20, iliac artery 17, femoral artery 31, popliteal artery 41, tibial artery 9 and upper limb artery 20.Most the patients (87.9%)were over 31 years old;92 cases were secondary to organic cardiac diseases. Embolectomy was performed in 42 limbs(41 patients).Thrombolytic drugs-urokinase and general drugs were used in 33 and 47 cases respectively. The results were excellent in 41 limbs, good in 28 limbs,poor in 29 limbs and 35 limbs (22.8%) were amputated.The mortality rate was 13.6%.67 limbs in 59 patients have been followed up for 6 months to 20 years.The long-term results were excellent in 30 limbs (44.8%) , good in 24 limbs (35.8%) and poor in 13 limbs (19.4%) .Selection of therapeutic methods and improvement of the results were discussed.

本文报告近25年来诊治的急性肢体动脉栓塞124例,栓塞138条动脉(腹主动脉下端20例)156条肢体。除3例未治外,共施行125例次治疗,其中施行传统取栓术41例42次,溶栓药尿激酶和一般药物分别治疗36和47例次。治疗结果以肢体计算:优41,良28,差29,截肢35(22.4%),总死亡率为13.6%。对59例67条肢体的远期效果是:优44.8%良35.8%,差19.4%。对选择治疗方法和提高治效果问题进行了讨论。

In this article a system of fibrinolytic activity assay for observation of thrombolytic drugs was described. The techniques, perfused rat hindlegs, fibrin plate assay, SDS-PAGE and fibrin autography were applied and modified. We have been used this system to analyze PA activity induced by thrombolytic drugs from endothelial cells and to characterized on the basis of molecular weight and immunological criteria of PA. This is an effecative series for effect and mechanism of thrombolytic drugs...

In this article a system of fibrinolytic activity assay for observation of thrombolytic drugs was described. The techniques, perfused rat hindlegs, fibrin plate assay, SDS-PAGE and fibrin autography were applied and modified. We have been used this system to analyze PA activity induced by thrombolytic drugs from endothelial cells and to characterized on the basis of molecular weight and immunological criteria of PA. This is an effecative series for effect and mechanism of thrombolytic drugs in cardiovascular system.

本文介绍一组大鼠肢体血管灌流模型、纤维蛋白平板测定、SDS—聚丙烯酰胺凝胶电泳和纤维蛋白自显影方法系列,用以观察纤溶系统的功能状态。通过纤溶酶原激活剂的释放作用,其活性大小及免疫学特性,研究溶栓药对纤溶系统的作用及机理,从而为临床血栓性疾病的用药和治疗提供帮助。

The changes of fibrinolytic activity and effects of thrombolytic drugs were investigated in plasma of 54 patients with AMI. The activity of t-PA, Plasmin (PL) andELA were significantly decreased (respectively P<0.05, 0.01, 0.05 vs 23 health subjects) , on the contrary, PA inhibitor (PAI) activity were increased (P<0.01)SVATE, iv 2.5 U/day for 2 weeks, gradually increased t-PA, PL, ELA activity and FDP content but decreased PAI and Fg in 13 AMI. The effects of fibrinolysis above were recovered to normal...

The changes of fibrinolytic activity and effects of thrombolytic drugs were investigated in plasma of 54 patients with AMI. The activity of t-PA, Plasmin (PL) andELA were significantly decreased (respectively P<0.05, 0.01, 0.05 vs 23 health subjects) , on the contrary, PA inhibitor (PAI) activity were increased (P<0.01)SVATE, iv 2.5 U/day for 2 weeks, gradually increased t-PA, PL, ELA activity and FDP content but decreased PAI and Fg in 13 AMI. The effects of fibrinolysis above were recovered to normal level during 2-3 weeks with SVATE. UK,iv 1000000 U once, induced a big immediate and transient changes in fibrinolytic activity in 14 AMI. On the contrary, treatment of routine caused the slow changes in fibrinolytic activity. These results suggested that the effects of SVATE in fibrinolysis was not so great as that UK at early stage of AMI and combined treatment with both SVATE and UK may be effective in AMI.

本文通过观察纤溶系统活性,纤维蛋白原(Fg)、纤维蛋白降解产物(FDP)含量变化,探讨蛇毒抗栓酶(SVATE)、UK溶栓治疗对急性心肌梗塞(AMI)的临床意义。结果表明,静脉一次大剂量UK治疗,患者血浆PL、ELA、t-PA活性和FDP出现快速大幅度增高,PAI、Fg降低、这种作用仅持续短时间、SVATE静脉首次大剂量以后小剂量维持2周处理,血浆上述纤溶指标逐渐恢复,ELA、t-PA和PAI活性2~3周接近正常水平。结果提示,SVATE、UK溶栓治疗使AMI患者纤溶功能得到改善,若采用二者联合用药,效果可能更理想。

 
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