Method: In the double blind study,40 patients were randomized to receive either low dose morphine 1mg (morphine group,n=20) or the same volume of normal saline solution (control group,n=20) intra articularly at the end of arthroscopic knee surgery. Analgesic efficacy was evaluated by visual analogue scale (VAS) 8 and 24 hours after the administration of morphine or placebo.
METHODS: One hundred and seven patients with depression were randomly divided into 3 groups: in a double blind study, moclobemide group of 25 patients (M 16, F 9; age 36 a±s 10 a) was treated with moclobemide, 200 mg, po , bid;
Multiple doses of the prepared (R/S)-PFF·HCl,(R)-PPF·HCl,(S)-PPF·HCl tablets and placebo were given to 8 healthy volunteers in a randomized crossover and double blind study. Pharmacokinetics parameters for (S)-and (R)-PPF following administration of the pure isomers and the racemate were calculated and compared.
Eighty-one psychoneuro-ses with anxiety, insomnia and excitation were treated by estazolam and diaze-pam under double blind study. Results indicated that estazolam(4mg,im)is more effective than diazepam(10mg,im )for all eases with different kinds of psychic disturbance.
Methods: A prospective randomized double blind study was carried out in 51 pregnant women as treatment group (including 22 cases as treatment group 1 and 29 cases as treatment group 2) and 51 pregnant women as controls (including 28 cases as controls group 1 and 23 cases as control group 2).
METHODS:Using randomized group sampling and double blind study,the quality of life evaluated by the life quality index and cost of treatment for depression with sertraline, fluoxetine or paroxetine were observed in 71 patients with depression.