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clinicopathologic factors
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  临床病理因素
     Expression of caspase-7,caspase-3,survivin in breast neoplasm and their relationship with clinicopathologic factors
     乳腺癌caspase-7、caspase-3、survivin的表达及与临床病理因素关系的探讨
短句来源
     Objective:To investigate the expression of P53、c-erbB-2、nm23 and CEA in untreated lung cancer and the relationship with clinicopathologic factors.
     目的:探讨P53、c-erbB-2、nm23及CEA在未经治疗的肺癌中的表达及与临床病理因素的关系。
短句来源
     The relationship between expression of survivin, P53, Bcl-2 with the clinicopathologic factors in non-small cell lung cancer
     Survivin、P53、Bcl-2蛋白与非小细胞肺癌临床病理因素的关系
短句来源
     Interestingly, we found TNFR1, TNFR2 and TRAF2 in papillary thyroid carcinoma were higher than those in follicular thyroid carcinomas(TNFR1,P<0.05;TNFR2,P<0.001;TRAF2,P<0.01). But they were not related to other clinicopathologic factors.
     它们在乳头状甲状腺癌中的表达明显高于在滤泡状甲状腺癌中的表达(TNFR1,P<0.05; TNFR2,P<0.001; TRAF2,P<0.01),但与甲状腺癌的其它临床病理因素无关。
短句来源
     Methods:The expression of TGF-β1 in seventy patients with CRC and 10 normal colorectal mucosal tissues were examined by immunohistochemistry,and the expression of TGF-β1 was analyzed with relation to clinicopathologic factors and post-operative survival.
     方法 :运用免疫组化S -P法检测 70例大肠癌组织、10例正常大肠粘膜组织标本的TGF - β1表达 ,并分析TGF - β1表达与大肠癌临床病理因素及术后生存率的关系。
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  病理因素
     Expression of caspase-7,caspase-3,survivin in breast neoplasm and their relationship with clinicopathologic factors
     乳腺癌caspase-7、caspase-3、survivin的表达及与临床病理因素关系的探讨
短句来源
     Objective:To investigate the expression of P53、c-erbB-2、nm23 and CEA in untreated lung cancer and the relationship with clinicopathologic factors.
     目的:探讨P53、c-erbB-2、nm23及CEA在未经治疗的肺癌中的表达及与临床病理因素的关系。
短句来源
     The relationship between expression of survivin, P53, Bcl-2 with the clinicopathologic factors in non-small cell lung cancer
     Survivin、P53、Bcl-2蛋白与非小细胞肺癌临床病理因素的关系
短句来源
     Interestingly, we found TNFR1, TNFR2 and TRAF2 in papillary thyroid carcinoma were higher than those in follicular thyroid carcinomas(TNFR1,P<0.05;TNFR2,P<0.001;TRAF2,P<0.01). But they were not related to other clinicopathologic factors.
     它们在乳头状甲状腺癌中的表达明显高于在滤泡状甲状腺癌中的表达(TNFR1,P<0.05; TNFR2,P<0.001; TRAF2,P<0.01),但与甲状腺癌的其它临床病理因素无关。
短句来源
     Methods:The expression of TGF-β1 in seventy patients with CRC and 10 normal colorectal mucosal tissues were examined by immunohistochemistry,and the expression of TGF-β1 was analyzed with relation to clinicopathologic factors and post-operative survival.
     方法 :运用免疫组化S -P法检测 70例大肠癌组织、10例正常大肠粘膜组织标本的TGF - β1表达 ,并分析TGF - β1表达与大肠癌临床病理因素及术后生存率的关系。
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  临床病理学因素
     Methods Clinicopathologic factors were analyzed in the gastrectomy specimen of gastric cancer in 16 young patients and 227 older patients by pathologic,immunhistochemical and histochemical examinations.
     方法应用病理组织学与组织化学、免疫组化以及18项临床病理学因素分析了手术切除的16例青年胃癌以及227例中老年胃癌的临床病理学特征,并比较两者在临床病理学方面的差异。
短句来源
     Conclusion Analysis of TGF-β1, TRF Ⅱ, Smad 2 and clinicopathologic factors be of significant value in judging the biological behaviors, recurrence and prognosis of non-small cell lung carcinoma.
     结论 非小细胞肺癌TGF - β1、TRFⅡ及Smad 2的表达与临床病理学因素的分析对于判断其局部生物学行为、复发及预后具有重要意义。
短句来源
  “clinicopathologic factors”译为未确定词的双语例句
     Methods:The level of p53, C-erbB-2, p21WAF1 and CDK4 were detected with immunohistochemical staining method in 120 breast tissues species. The relationship between p53, C-erbB-2, p21WAF1, CDK4 and some clinicopathologic factors were analyzed.
     方法:采用免疫组化SP法检测120例乳腺癌组织石腊切片上p53、C-erbB-2、p21WAF1和CDK4的表达。
短句来源
     Correlations between the expressions of Beclin 1 gene and the clinicopathologic factors of cervical squamous cell carcinoma were statistically analyzed. Results The rates of negative, weak, strong expression of Beclin 1 in cervical squamous cell carcinoma were 43.2% (35/81), 34.6% (28/81) or 22.2% (18/81) respectively, and the significantly lower than those in normal cervix and CIN Ⅱ-Ⅲ(P=0.011).
     结果宫颈鳞癌组织中Beclin1阴性、弱阳性、强阳性表达率依次是43.2%(35/81)、34.6%(28/81)、22.2%(18/81),与正常宫颈和宫颈上皮内瘤样病变组相比,Beclin1在宫颈鳞癌中的表达显著下调(P=0.011)。
短句来源
     the expression of Syk protein was related to the distant metastasis and survival rate(P<0.01),but was not related to other clinicopathologic factors such as cerbB-2,Cath-D and VEGF protein,and the clinical stage as well as histological grade or axillary lymph node(P>0.05).
     Sky蛋白表达与乳腺癌术后远端转移及5年生存率密切相关(P<0.01),但与c-erbB-2、Cath-D、VEGF等肿瘤转移相关因子以及临床分期、病理学分级、腋窝淋巴结转移等病理参数无关(P>0.05)。
短句来源
     6. There were no significantly correlation between the over expression of VEGF-C and VEGFR-3 and clinicopathologic factors such as ER, PR, P53, c-erbB-2, and the size, number, clinical stage and pathologic type of breast carcinoma.
     6、本组资料中VEGF-C、VEGFR-3在乳腺癌不同位置的表达与ER、PR、P53、c-erbB-2表达,以及肿瘤大小、个数、临床分期和病理类型无关。
短句来源
     Methods:Specimens of 84 GIST cases were collected along with their clinicopathologic data. VM channels were detected using CD31/PAS double staining and CD117 and CD31 immunohistochemical staining and were then used to study the correlation between VM and clinicopathologic factors.
     方法:收集84例GIST标本及临床病理资料,CD31/PAS双重染色结合CD117、CD31免疫组化染色证实VM存在,分析VM与患者临床病理指标之间的关系。
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  clinicopathologic factors
This study examined the correlation between the mucin phenotype of early SIG and its clinicopathologic factors, particularly for the sake of less invasive surgery.
      
There was no apparent relationship between theexpression pattern and clinicopathologic factors (P >amp;gt;0.1, respectively), except a positive correlation withhistologic grading (P = 0.04).
      
The clinicopathologic factors studiedfor prognostic value were age, tumor location, tumordifferentiation, preoperative serum levels ofcarcinoembryonic antigen, Dukes' stage, and IVaseactivity in colorectal cancer tissue.
      
This study demonstrates that PEA3 expression is not correlated with HER-2/neu expression in breast cancer tumor tissues, nor is it associated with adverse clinicopathologic factors or prognosis.
      
In contrast to HER-2/neu, PEA3 expression was not correlated with prognosis or major clinicopathologic factors, except for a negative correlation with lymphovascular permeation ( p=0.007).
      
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AIMS\ To investigate the relationship between the expression of nm23 protein and metastatic potential in human hepatocellular carcinoma. METHODS\ The nm23 proteins were detected in 24 patients with hepatocellular carcinoma by immunogold silver staining method. The specific antibody was rabbit antihuman NDPK (Chain A,B) antibody. RESULTS\ NDPK level does not statistically correlate with both metastatic potential and some other clinicopathologic factors such as tumor size, number and the background liver...

AIMS\ To investigate the relationship between the expression of nm23 protein and metastatic potential in human hepatocellular carcinoma. METHODS\ The nm23 proteins were detected in 24 patients with hepatocellular carcinoma by immunogold silver staining method. The specific antibody was rabbit antihuman NDPK (Chain A,B) antibody. RESULTS\ NDPK level does not statistically correlate with both metastatic potential and some other clinicopathologic factors such as tumor size, number and the background liver diseases(P>0.05). CONCLUSIONS\ The combined products expression of nm23 gene (NDPK_A,B) does not relate to the metastatic potential in human hepatocellular carcinoma.

目的探讨肝脏冷保存与移植肝原发性无功能的关系。方法采用具有免疫耐受性的同种大鼠原位肝移植模型进行研究。将鼠肝分别在4℃UW液中保存1,6和24h,分别在移植后1h和24h取肝脏做病理观察。结果保存在UW液中的肝脏基本保存了正常的组织结构,而在移植后则不同程度地出现了变性或坏死,并且肝细胞的坏死是以小叶中央静脉为中心。保存时间越长,病变越严重。结论肝脏冷保存时间与移植肝原发性无功能的发生密切相关。

Objective : To study the clinicopathologic factors for lymphatic metastasis of the vulvar carcinoma. Methods : 48 cases of the vulvar carcinoma were analysed in clinicopathology. S%, PI (Prolificative Index), DI (DNA Index) and rasP 21 in 31 cases were studied using flow cytometry. Results : S%, PI and DI of the vulvar carcinoma with lymphatic metastases were 14.33%, 24.86 and 1.22 respectively, which were significantly higher than those with no lymphatic metastases. The lymphatic metastasis rates...

Objective : To study the clinicopathologic factors for lymphatic metastasis of the vulvar carcinoma. Methods : 48 cases of the vulvar carcinoma were analysed in clinicopathology. S%, PI (Prolificative Index), DI (DNA Index) and rasP 21 in 31 cases were studied using flow cytometry. Results : S%, PI and DI of the vulvar carcinoma with lymphatic metastases were 14.33%, 24.86 and 1.22 respectively, which were significantly higher than those with no lymphatic metastases. The lymphatic metastasis rates of vulvar carcinoma were 6.25% and 62.50% in clinical stage Ⅰ+Ⅱ and stage Ⅲ+Ⅳ, and were 9.09%, 34.78% and 2/3 in histologic degrees Ⅰ,Ⅱ and Ⅲ respectively. The lymphatic metastasis of vulvar carcinoma was related to clinical stage, S%, PI, DI and histologic degree. The survival rate after operation of the vulvar carcinoma with no lymphatic metastases was significantly higher than that with lymphatic metastases. Conclusions : Clinical stage, S%, PI, DI and histologic degree are important factors for the lymphatic metastasis of vulvar carcinoma.

对48例外阴鳞状细胞癌的淋巴结转移相关因素进行了临床病理分析,并应用流式细胞术(flowcytometryFCM)对其中的31例检测了细胞增殖活力、DNA含量、rasP21等。结果显示:发生淋巴结转移的外阴癌细胞的S%、PI和DI值显著高于未发生转移者;临床期别晚、组织分化差的外阴癌的淋巴结转移率显著增高。认为临床分期、S%、PI、DI值及组织学分级是影响外阴癌淋巴结转移的重要因素。

Abstract AIMS To investigate the correlation between microvessel count and various clinicopathologic factors and prognosis of gastric carcinoma using immunohistochemical staining with anti factor Ⅷ related antigen (F ⅧRAg) antibody. METHODS A total of 128 specimens resected from patients with gastric carcinoma were investigated by immunohistochemical staining with a monoclonal antibody against F ⅧRAg. Correlations between the microvessel count (the mean number of microvessel in the five areas...

Abstract AIMS To investigate the correlation between microvessel count and various clinicopathologic factors and prognosis of gastric carcinoma using immunohistochemical staining with anti factor Ⅷ related antigen (F ⅧRAg) antibody. METHODS A total of 128 specimens resected from patients with gastric carcinoma were investigated by immunohistochemical staining with a monoclonal antibody against F ⅧRAg. Correlations between the microvessel count (the mean number of microvessel in the five areas of highest vascular density at 200× magnification) and various clinicopathologic factors and prognosis of 86 cases with complete follow up data were studied.

目的研究胃癌组织中微血管数量(MVC)与临床病理因素及预后关系。方法使用针对因子Ⅷ相关抗原(FⅧRAg)的单克隆抗体免疫组化方法,对128例胃癌患者手术切除标本的微血管进行定量(取镜下200倍5个最高血管密度区的MVC均数)分析MVC与临床病理因素之间关系,并对其中有完整5年随访资料的86例胃癌患者预后与MVC关系进行探讨。结果所有患者的平均MVC为165±85,MVC随TNM分期增加而增加,有淋巴结转移患者的MVC(183±87)明显高于无淋巴结转移患者(138±74)(P<001),高MVC(≥16)胃癌患者比低MVC(<16)患者预后明显为差(5年生存率分别为425%,587%,P<005)。结论MVC在胃癌患者是一个有意义的预后因素。

 
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