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abnormally increased
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  异常升高
     ? Conclusion 1. NF-κB and AP-1 DNA-binding abilities were abnormally increased in the renal cortex of rats with ADR-induced nephrosis.
     结论 ①阿霉素肾病大鼠肾皮质中NF -κB、AP - 1DNA结合活性异常升高
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     Conclusion The DNA-binding ability of NF-κB is abnormally increased and that of GR is decreased in cells from cortex of kindey in Adriamycin-induced nephrotic rats.
     结论ADM肾病大鼠肾皮质中NF-κB DNA结合活性异常升高,GR活性降低。
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     Result: The expression of IL-1βmRNA and IGF-1mRNA in UC rats abnormally increased, and reduced after treating by herbs-partition moxibustion.
     结果溃疡性结肠炎大鼠结肠IL1βmRNA、IGF1mRNA表达异常升高,隔药灸治疗能降低其表达。
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     The abnormally increased level of BUN,CRE,urine ALB and β2-MG output occurred in all patients before anti-shock therapy,which were not statistically different among the three groups.
     所有患者BUN、CRE、尿ALB和β2-MG定量均异常升高,但组间差异无统计学意义。
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     Conclusion Buflomedil hydrochloride may have neuroprotective effect on neurological injury caused by focal cerebral ischemia, and its mechanism may be associated with the reducing of abnormally increased endothelin and the increased levels of CGRP in brain tissues after cerebral ischemia.
     结论丁咯地尔对局灶性脑缺血所造成的大鼠神经功能损伤具有保护作用,其机制可能与降低脑缺血后脑组织中异常升高的内皮素、增加脑组织中CGRP的含量有关。
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  异常升高的
     ResultsIn the treated group, the abnormally increased levels of IgG, IgM, C 3, C 4, CD 8 + and CD 19 + began to lower at 1st-2nd week after treatment, and basically restored to the levels of normal at 3rd-4th week;
     结果应用黄芪注射液后 ,异常升高的IgG、IgM、C3、C4 、CD8+和CD19+于治疗后第 1~ 2周开始下降 ,且于第 3~ 4周基本恢复到正常组水平 ;
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     Secretion of both Th1 and Th2 cytokines stimulated by PDB plus ionomycin were inhibited by CKZ, and CKZ could also inhibit the abnormally increased secretion of INF-γ,TNF-α,IL-6 and IL-10 in patients with influenza.
     喘可治对PDB加离子霉素诱导的PBMCs分泌Th1和Th2细胞因子具有抑制作用,并能抑制流感病人异常升高的INF-γ、TNF-α、IL-6和IL-10分泌。
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     The common effect of abnormally increased IL 10 and adhesion molecules is the major cause of RA patients' pathologic damage.
     异常升高的IL 1 0与细胞粘附分子的共同作用是导致RA患者病理损伤的重要原因
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     CONCLUSION: Both membranous milkvetch root of high and low dosages plus danshen parenteral solution can significantly decrease the insulin resistance of the patients with cerebral infarction at convalescence, ameliorate the abnormally increased blood lipid and viscosity, and improve the clinical effects, and the effects of high dosage membranous milkvetch root are better.
     结论:高剂量和低剂量黄芪合丹参注射液均有显著降低脑梗死恢复期患者胰岛素抵抗、改善异常升高的血脂、血黏度,并有提高临床疗效的作用,以高剂量黄芪为优。
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     Conclusion Buflomedil hydrochloride may have neuroprotective effect on neurological injury caused by focal cerebral ischemia, and its mechanism may be associated with the reducing of abnormally increased endothelin and the increased levels of CGRP in brain tissues after cerebral ischemia.
     结论丁咯地尔对局灶性脑缺血所造成的大鼠神经功能损伤具有保护作用,其机制可能与降低脑缺血后脑组织中异常升高的内皮素、增加脑组织中CGRP的含量有关。
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  异常增高
     Results The pretreatment level of lactic dehydrogenase was abnormally increased in Ⅰ+Ⅱ patients were 42.9%(21/49),and in Ⅲ+Ⅳ patients were 64.8%(46/71),So the increaseing of the level of lactic dehydrogenase in Ⅲ+Ⅳ patients took more importance.
     结果 治疗前Ⅰ期 +Ⅱ期患者血清乳酸脱氢酶异常增高为 42 9% (2 1/4 9) ,Ⅲ期 +Ⅳ期患者血清乳酸脱氢酶异常增高为 64 8% (4 6/71) ,以Ⅲ期 +Ⅳ期患者血清乳酸脱氢酶异常增高为普遍 (P <0 0 5 )。
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     Conclusion The serum SIL-2R levels of HIV infected patients abnormally increased, are much higher than those of normal controls and patients with hepatitis C, the highest levels are in the HIV/AIDS patients complicated with hepatitis C.
     结论 SIL 2R在HIV感染者外周血中异常增高 ,高于丙型肝炎与正常人 ,HIV感染合并丙型肝炎患者则进一步升高。
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     The levels of CD - 3/CD + (16+56) , CD + 3/CD + (16+56) and CD - 3/HLA DR + were significantly increased in the group with rejection. The four parameters mentioned above in patients with acute nephrotubal necrosis were all abnormally increased as two times as those of the group with rejection.
     术后排斥者的CD-3/CD+(16+56)、CD+3/CD+(16+56)、CD-3/HLADR+及CD+3/HLADR+较稳定者显著升高,而急性肾小管坏死者的上述4个指标异常增高,是排斥组的2倍。
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     Conclusion Hepatic IL-4 and IFN-γ protein expression were obviously increased in BALB/c rats with liver fibrosis. Cordyceps had superior anti-fibrosis and anti-liver injury,its mechanism might be through down-regu- lating the abnormally increased Th immune response.
     结论肝纤维化 BALB/c 小鼠的肝脏 IL-4与 IFN-γ均明显上升,虫草制剂有良好的抗肝损伤与肝纤维化作用,其作用机制与下调异常增高 Th 免疫应答有关。
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     Conclusion: Triptolide can inhibit the abnormally increased NF κB activity with the development of aneurysm, so it can prevent hypertensive aneurysm formation.
     结论 :雷公藤内脂醇可通过抑制脑动脉瘤形成过程中异常增高的NF κB活性 ,进一步防止动脉瘤的发生。
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  “abnormally increased”译为未确定词的双语例句
     Results ①p-STAT3 protein was abnormally increased in SCC (P<0.001).
     结果①p-STAT3的水平在SCC中呈明显上调(P<0.001);
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     Conclusion:The apoptosis of SLE T lymphocytes abnormally increased,especially of CD4 + subpopulation,which resulted in the decrease of CD4/CD8 ratio.
     结论 :SLE患者体内T细胞凋亡增多 ,以CD4 + T细胞凋亡增加更为显著 ,导致CD4 CD8比值下降 ;
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     Results ① The positive rate of p-STAT3 protein expression was abnormally increased in SCC and BCC as compared to normal skin and SK (p < 0.01).
     结果 ①p-STAT3在皮肤SCC、BCC中表达的阳性率与正常皮肤和皮肤SK相比明显增高(p<0.01);
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     Results ①The peak velocity of MCA of the damaged side was abnormally increased by 35.1% and decreased by 40.5% .
     结果 ①常规经颅彩色多普勒检查脑梗死患侧MCA峰值流速表现为异常加快(35. 1% )、降低(40. 5% )、正常(24. 4% )。
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     the chronical CIF-administration to the model rats could decrease the B_ max of 5-HT_1 and 5-HT_2 receptors in the frontal cortices ( P <0.01),which implied a decrease in the abnormally increased numbers of the receptors.
     柴地合方慢性治疗可使慢性应激抑郁大鼠前额皮层 5 HT1、5 HT2 受体的Bmax 降低 (P <0 0 1) ,使抑郁大鼠异常增加的受体数目减少。
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  abnormally increased
The possibility to use riluzole for correction of abnormally increased hyperexcitability of the spinal neuronal systems is discussed.
      
Suppression of abnormally increased excitability of monosynaptic spinal reflex arcs by riluzole
      
In these cases, immediately after the MRD peak had been reached, abnormally increased responses (AIR) developed, whose amplitude was 2-2.5 times higher than the amplitude of highly facilitated MRD.
      
Both meal-stimulated and nocturnal acid secretions have been shown to be abnormally increased in patients with duodenal ulcer.
      
This study suggests that lesions of the intramural nervous system of the gut in Chagas' disease do not appear to be associated with abnormally increased duodenogastric reflux.
      
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Muscle biopsies of 3 patients and 3 carriers in a family with Becker type muscular dystrophy were performed.Myopathological changes could be demonstrated in all 3 carriers. The changes of myonuclei were more prominent than the changes of contractile element, and were progressive along with their age. However, the muscle power remained normal because the pathological changes were less extensive and not severe. It is perhaps reasonable to consider the carriers as subclinical cases. The myopathology of the 3 patients...

Muscle biopsies of 3 patients and 3 carriers in a family with Becker type muscular dystrophy were performed.Myopathological changes could be demonstrated in all 3 carriers. The changes of myonuclei were more prominent than the changes of contractile element, and were progressive along with their age. However, the muscle power remained normal because the pathological changes were less extensive and not severe. It is perhaps reasonable to consider the carriers as subclinical cases. The myopathology of the 3 patients included abnormally increased variation of fiber size, degenertive changes of muscle fibers, formation of sarcolemmal tubes, phagocytosis of necrotic muscle fibers, muscle fiber fibrosis and infiltration of adipose tissue etc.For finding out the earliest pathological changes it is important to understand the pathogenesis of the disease. In this respect, attention should be paid on changes of myonuclei.

作者等对一个Becker型肌营养不良症家系中的3名患者与3名递体进行了肌肉活组织检查。3例递体均有肌肉病理改变。肌核变化比收缩部份变化明显,其病变随年龄增长而加重,提示递体的肌肉病变也是缓慢进行的,因病变不重,范围不广,而不足以引起肌力减退。从而或可将递体认为是亚临床病例。患者的病肌变化包括肌纤维粗细不匀、变性、肌管形成、坏死、被噬、纤维化与脂肪浸润等。肌核变化也明显。包括肌核增生,中央肌核,链状排列与成簇等。递体的肌肉,早期出现肌核变化。寻找病损的最早部位,有利于了解病机,在这方面,除肌膜外尚需注意肌核。

Comparison between A method in which HGG was emeioyed as substrate and Liyuan method was made for estimation of serum anglotension cenvetiong enzyme (SACE) activity. Significant correlation between the two methods was found (r=0.87; P<0.01) . No difference was found between the percentage of abnormally-increased SACE estimated by two methods in patients with sarcoidosis, hyperthyroidism, etc. So two methods had the same diagnostic significance in some diseases.Because of the excellent linear relation...

Comparison between A method in which HGG was emeioyed as substrate and Liyuan method was made for estimation of serum anglotension cenvetiong enzyme (SACE) activity. Significant correlation between the two methods was found (r=0.87; P<0.01) . No difference was found between the percentage of abnormally-increased SACE estimated by two methods in patients with sarcoidosis, hyperthyroidism, etc. So two methods had the same diagnostic significance in some diseases.Because of the excellent linear relation and reproducibility, ease of obtaining and inexpensiveness of the agents used in method A, it might be regarded as one of the reliable methods for estimation of SACE.

本文应用以马尿酰甘氨酰甘氨酸(HGG)为底物的紫外分光光度法与笠原法对血清血管紧张素转换酶(ACE)活性测定进行比较。对结节病、甲亢等血清ACE活性增高患者阳性率无差异。两法相关良好(r=0.87,P<0.01)有同等参考价值。该法的直线性、重复性良好。

With a double-blind,placebo-controlled design,we observed the changes of white blood cell system and platelelet among the EHF patients(91 cases treated with ribavirin and 74 with placebo).We noticed a very rapid down-back of white blood cell count and up-back of platelet in the ribavirin- treated patients,which had abnormally increased and decreased respective- ly in the course of disease.On the 2nd,4th and 6th illness day,there are significant differences between the two groups of patients in two parameters,ie:P<0.05(WBC)and...

With a double-blind,placebo-controlled design,we observed the changes of white blood cell system and platelelet among the EHF patients(91 cases treated with ribavirin and 74 with placebo).We noticed a very rapid down-back of white blood cell count and up-back of platelet in the ribavirin- treated patients,which had abnormally increased and decreased respective- ly in the course of disease.On the 2nd,4th and 6th illness day,there are significant differences between the two groups of patients in two parameters,ie:P<0.05(WBC)and P<0.01(Plat.)respectively.As to the leukemia-like reaction its occurrence in ribavirin-treated group is statistic- ally less than that in the placebo group.Both percentages of lymphocytes and the atypical lymphocyte count in the ribavirin group are smaller than those in the placebo group.The significant difference was observed on the 4th,11th(the percentage of lymphocytes) and the 2nd(aty- pical lymphocyte count)treatment day,respectively(P<0.05).These results indicate that ribavirin has the preventive effect on the EHF virus infection.The usage of it in the early phase of this disease will block the development of the illness,decrease the severity and the mortality of this disease.

用双盲、对照法,观察病毒唑对发病4天以内的165例流行性出血热患者(治疗组91例、对照组74例)病程中外周血白细胞及血小板的变化。用药后,病毒唑组增高的白细胞的下降,降低的血小板的回升,在第2,4、6研究日,较对照组明显(P<0.05及<0.01)。类白血病反应,亦较对照组低(P<0.01)。淋巴细胞百分数及异型淋巴数,分别在第2、4、10研究日较对照组低(P<0.05)。表明:病毒唑具有抗-EHF病毒感染的作用。如在病程早期应用,可阻断病情的发展,减轻疾病的严重程度,从而降低病死率。

 
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