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   cell period 在 眼科与耳鼻咽喉科 分类中 的翻译结果: 查询用时:0.201秒
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cell period
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  cell period
During this two-prothallial cell period before the third mitosis, plastids had large and complex fibrillar assemblies shown to be modified starch grains.
      
Comparisons of the entrainment properties of the model with experimental results show good agreement with similar modes and different entrainment ratios occurring for similar basic cycle lengths (as functions of the unperturbed cell period).
      
The duration of a one-cell period lasts about 6 hours.
      
Temporal variation of the peripheral cell period and maximum diastolic potential are also seen.
      
If s is large enough, the single-cell period distribution will be bimodal with mostly fast and slow cells, as was the case using curve D.
      
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Objective: To study the ability of Cisplatin, Mitoxantrone and Cytosine Arabinoside on inhibiting the proliferation of rabbit lens epithelial cells(RLECs). Methods: Lens epithelium was isolated and cultured, and 2~3 passage RLECs were placed in 96-well flat bottomed tissue culture plates and incubated for 24 hours, then exposed to different concentrations of Cisplatin, Mitoxantrone and Cytosine Arabinoside for 24 and 72 hours and the effect of RLECs were measured with methyl thiazolyl tetrazolium (MTT) assay....

Objective: To study the ability of Cisplatin, Mitoxantrone and Cytosine Arabinoside on inhibiting the proliferation of rabbit lens epithelial cells(RLECs). Methods: Lens epithelium was isolated and cultured, and 2~3 passage RLECs were placed in 96-well flat bottomed tissue culture plates and incubated for 24 hours, then exposed to different concentrations of Cisplatin, Mitoxantrone and Cytosine Arabinoside for 24 and 72 hours and the effect of RLECs were measured with methyl thiazolyl tetrazolium (MTT) assay. The apoptosis of cells were observed with transmission electron microscope (TEM) .The changes of cell period were observed with flow cytometer (FCM). Results: The IC50 of cisplatin and mitoxantrone exposed to RLECs for 24 hours were 38.92μg/ml 、8.92μg/ml and those of 72 hour were 6.71μg/ml、2.04μg/ml respectively. Conclusion: Cisplatin and Mitoxantrone were dose- dependent and time-dependent inhibitors. Both of them inhibited the proliferation of RLECs effectively , Cytosine Arabinoside, however, had no obvious effect on RLECs in this experimental condition.

目的:研究顺铂(Cisplatin ,PDD),米托蒽醌(Mitoxantrone, Mit),阿糖胞苷(Cytosine Arabinoside, Ara-C)对兔晶体上皮细胞(rabbit lens epithelial cells, RLECs)増殖的抑制作用。方法:分离兔晶体囊膜行组织细胞培养,传代的2~3代RLECs在96孔板培养24h,然后用不同浓度的PDD、Mit及Ara-c作用细胞24h及72h,用MTT(methyl thiazolyl tetrazolium)比色法进行测定。电镜观察细胞超微结构,流式细胞仪观察细胞周期的变化。结果:PDD及Mit作用于传代培养RLECs 24h IC50分别为38.92μg/ml 、8.92μg/ml ;72h 的 IC50 分别为6.71μg/ml、2.04μg/ml。结论:PDD及Mit均为剂量依赖型和时间依赖型药物,均能有效抑制兔晶体上皮细胞的生长,在此试验条件下Ara-C对兔晶体上皮细胞增殖无明显抑制作用。

 
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