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cross reactive
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  交叉反应
     High resolution DNA typing for HLA B40 cross reactive groups
     HLA-B40交叉反应组高分辨度DNA分型
短句来源
     The horse IgG, isolated from a sample anti-human IgE antiserum by ion exchange chromatography on QAE-Sephadex A-50, was purified by affinity chromatography on Sepharose 4B coupled with human umbilical plasma and rabbit IgG anti-humansera for absorbing the cross reactive antigens.
     马抗人IgE血清通过QAE—Sephadex A-50离子交换层析提取马IgG,再用兔抗人全血清、人脐血浆交联的Sepharose 4B亲和层析吸附交叉反应抗原而纯化。
短句来源
     Objective To investigate the application and significance of human leukocyte antigen (HLA) and cross reactive groups(CREGs) matching in clinical renal transplantation.
     目的 探讨人白细胞抗原 (HLA)交叉反应组 (CREGs)配型原则在临床肾移植中的应用及意义。
短句来源
     A comparison of serological and high resolution DNA methods for HLA B40 cross reactive groups typing
     HLA-B40交叉反应组血清学与高分辨度DNA分型的比较研究
短句来源
     Clinical study of HLA and cross reactive groups matching in sensitized recipients of kidney transplantation
     HLA和交叉反应组配型在致敏受者肾移植中的临床应用研究
短句来源
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  交叉反应的
     Both HPV6b and HPV11 share neutralizing epitopes which are cross reactive and HPV6b VLP may be used in prophylactic and therapeutic vaccine for HPV6b and/or HPV 11 infections.
     HPV6b和 11型间确实存在交叉反应的中和表位 ,HPV6bVLP有可能用于防治HPV6b及HPV11感染的疫苗
短句来源
     Methods Peripheral blood monoclear cells (PBMCs) were isolated from healthy, SIV-negative rhesus monkeys (M.mulatta) using Ficoll-Hypaque density separation. DC precursors were identified and were sorted by 3 color rare-event cytometric flow analysis using human monoclonal antibodies cross reactive with rhesus monkey.
     方法 采集健康、SIV阴性的恒河猴外周血 ,用Ficoll Hypaque梯度离心法提取外周血单核细胞 (PBMC) ,利用与恒河猴有交叉反应的人单克隆抗体以及三色流式细胞仪分离 pDC1和pDC2 ,并对其进行细胞表现型的鉴定。
短句来源
     After 11 days,all animals were anesthetized with Ketamine and peripheral blood samples were collected. Ficoll-Hypaque density method was used to separate the mononuclear cells of peripheral blood. pDC 1 and pDC 2 were isolated by rare-event cytometric flow analysis using human monoclonal antibodies cross reactive with rhesus monkey and compared with those not treated with rhFlt3L in quantity and phenotypes.
     方法 健康猴艾滋病毒SIV阴性的恒河猴每日给予rhFlt3L 10 0 μg/kg体重皮下注射 ,于第 11天在氯胺硐全麻下采集静脉血 ,用Ficoll Hypaque梯度离心法提取外周血单核细胞 ,利用与恒河猴有交叉反应的人单克隆抗体以及三色流式细胞仪分离 pDC1和 pDC2 ,并与未经Flt3L作用的 pDC1和pDC2 在数量和细胞表现型上进行对比。
短句来源
  “cross reactive”译为未确定词的双语例句
     Objective To confirm human papillomavirus (HPV) 6b virus like particles (VLP) have strong immunogenicity and the protective antibody induced by HPV 6b VLP have cross reactive immunity against HPV11 VLP and bovine papillomavirus (BPV) 1 VLP.
     目的 了解人乳头瘤病毒 (HPV) 6b型病毒样颗粒 (VLP)的免疫活性及其诱导的保护性抗体对HPV11型VLP和牛乳头瘤病毒 1型 (BPV1)VLP的交叉免疫反应。
短句来源
     Results:1.Neutralization test in vitro showed that monoclonal antibody 5B 4 6 had a cross reactive neutralization activity to HSV 1 and HSV 2, the neutralization tiers to HSV 1 was significantly higher than that to HSV 2 and the neutralization titers in the presence of complements (fresh Guinea pig serum) significantly higher than that in the absence of complements.
     结果 :1 单抗腹水 5B4 6具有HSV 1及HSV 2交叉中和性 ,但对HSV 1的中和效应要强一些 ,其中和效价各为 1∶80 (豚鼠新鲜血清 (GPS)存在 ,HSV 1)、1∶2 0 (GPS缺乏 ,HSV 1)及1∶2 0 (GPS存在 ,HSV 2 )、1∶5 (GPS缺乏 ,HSV 2 )。
短句来源
     97 of 110 chronic schistosomiasis patients were positive,the positive rate was 88.18%), the cross reactive rate in 40 cases of clonorchiasis sinensis was 2. 5% (1/40), only one among 50 healthy pessons' sera was positive,the false positive rate was 2%.
     110例慢性血吸虫病人血清的阳性率为88.2%; 40例华支睾吸虫病人血清有1例出现阳性,交叉反应率为2.5%,50例健康人血清亦有1例出现阳性反应,假阳性率为2%.
短句来源
     Results A linear epitope consisting of amino acid (aa) 1 86 within nucleocapsid protein reading frame was determined and its core sequence consists of aa 15 66. Conclusion The linear epitope is a major and cross reactive antigenic epitope.
     结果 确定了S 基因产物———病毒核衣壳蛋白氨基端的一个B 细胞线性抗原表位,该表位覆盖aa1aa86 的范围,相当于S基因bp37294 ,其核心序列可能由aa1566 构成。
短句来源
     Results Among the 20 recipients,PRA was less than 20% in 12,and 20%~50% in the other 8. HLA A,B,DR from the doners and recipients were completely matched with cross reactive group(CREG) in 13,including A,B and DR was synchronally present in 6.Acute rejection occurred in 11 postoperative patients,in which 9 were reversed by impulsive therapy and 2 underwent renal resection (PRA 20% in 1 and 40% in the other).
     其中A、B、DR分别有一相同抗原的为 6例。 术后 11例发生急性排斥 ,经冲击治疗 9例逆转 ,2例肾脏摘除 (1例PRA为 2 0 % ,1例PRA为 40 % )。
短句来源
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  cross reactive
Two cross reactive antibodies neutralized the heterologous virus.
      
Of the YS8 cross-reactive antibodies the highest affinity (108 M-1) were also cross reactive with S81 (YGSLPQKAQGHRPQDEG) but not S49 (69-84-Gly), thus emphasizing the need for Tyr-68 for format stability of the determinant involved.
      
Cross reactive antigens shared by the host and the pathogen were detected first by immunodiffusion.
      
The 31 kD polypeptide is common to both species and immunologically cross reactive.
      
Compared to whole proteins, peptide subunits can focus immune responses on protective epitopes, and not on potentially harmful cross reactive antigens.
      
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The affinity column purified anti-DNP antibodies from secondary response of a single Wistar rat were used to immunize a rabbit. The serum of which was first absorbed with immunoglobulins of normal Wistar rats and then precipitate with ammonium sulphate. The anti-idiotypic specificities of the antibodies thus obtained were identified with ELISA, in which the walls of plate were coated with affinity column purified anti-DNP antibodies. With self Ig separated from preimmunized serum as control, the results showed...

The affinity column purified anti-DNP antibodies from secondary response of a single Wistar rat were used to immunize a rabbit. The serum of which was first absorbed with immunoglobulins of normal Wistar rats and then precipitate with ammonium sulphate. The anti-idiotypic specificities of the antibodies thus obtained were identified with ELISA, in which the walls of plate were coated with affinity column purified anti-DNP antibodies. With self Ig separated from preimmunized serum as control, the results showed that the antibodies were directed at the idiotypic determinants on anti-DNP antibodies of the Wistar rat. In order to test for cross reactive idiotypes on anti-DNP antibodies from other Wister rats, a reverse ELISA was used, i. e. the above characterized antiidiotypic antibodies rather than the anti-DNP antibodies were used to coat the plate. It was shown that the reverse ELISA could specifically detect and semiquantatively determine the idiotypes directly from serum. This reverse ELISA could afford facilities for researches in idiotype expression. The effect of blocking DNP combining site on the idiotype-antiidiotype reactions was also studied.

本文以“逆向”ELISA 测定 Wistar 大鼠抗 DNP抗血清中抗体的独特型,即以抗独特型抗体为涂布物来测定抗血清的效价。实验结果表明“逆向”ELISA可以专一地半定量测定大鼠抗 DNP抗血清的独特型,为进一步研究抗独特型抗体对抗体独特型表达的调节作用打下基础。同时,DNP-BSA封闭大鼠抗 DNP抗体的实验初步表明,这抗体的独特型决定簇位于抗体分子的抗原结合部位,至少十分接近抗原结合部位。

Monoclonal antibodies against H241 strain of dengue-4 virus were obtained from lymphocyte hybri-domas produced by fusing immune mouse lymphocytes with mouse myeloma cells. Hybridoma cell culture supernatants were screened by indirect immunofluorescent antibody technique. Monoclonal antibodies in mouse ascitic fluid induced by five selected hybridomas were characterized also by the immuno-fluorescence test. Two hybridoma-producing antibodies were type-specific for dengue-4. Their titers were 1:10,240-1:20,480...

Monoclonal antibodies against H241 strain of dengue-4 virus were obtained from lymphocyte hybri-domas produced by fusing immune mouse lymphocytes with mouse myeloma cells. Hybridoma cell culture supernatants were screened by indirect immunofluorescent antibody technique. Monoclonal antibodies in mouse ascitic fluid induced by five selected hybridomas were characterized also by the immuno-fluorescence test. Two hybridoma-producing antibodies were type-specific for dengue-4. Their titers were 1:10,240-1:20,480 and 1:2,560 respectively. The other two hybridoma antibodies were cross-reactive with dengue-2 virus. Another preparation was cross-reactive with dengue-1 virus.

用登革4型H241株病毒免疫的小鼠脾细胞与小鼠骨髓瘤细胞融合,获得了5个产生抗登革4型病毒单克隆抗体的杂交瘤细胞系。这些杂交瘤细胞的上清液及小鼠腹水抗体均用间接免疫荧光法检测。其中两个杂交瘤细胞系产生的抗体对登革4型病毒具有型特异性,它们的荧光抗体滴度分别为1:10,240~1:20,480和1:2,560。另两个细胞系产生的抗体对登革2型病毒有交叉;另1个对登革1型病毒有交叉。

Anti Beijing-duck-thyinocytes antiserum was obtained from rabbits immunized with Beijing duck thymocytes. After having absorbed the antiserum with cells from liver, bursa of Fabricins and red blood cells, there occurred no cross reactions with duck brain and Harderian gland cells. And the absorbed anti-duck-brain antiserum did not cross react with duck thymocytes either. Antiserum against Beijing duck thymocytes was cross reactive, with thymocytes from Beijing duck, chicken and Japanese quail, but not...

Anti Beijing-duck-thyinocytes antiserum was obtained from rabbits immunized with Beijing duck thymocytes. After having absorbed the antiserum with cells from liver, bursa of Fabricins and red blood cells, there occurred no cross reactions with duck brain and Harderian gland cells. And the absorbed anti-duck-brain antiserum did not cross react with duck thymocytes either. Antiserum against Beijing duck thymocytes was cross reactive, with thymocytes from Beijing duck, chicken and Japanese quail, but not with the thymocytes from pigeon, mouse and guinea pig. These results indicated that the antigen determinant(s) detected by the antiserum probably represents a common antigen detcrminant(s) shared by a part of birds.The first appearence of this antigen determinant(s) on the thymus and spleen colls of Beijing duck during ontogenesis was the 14th and the 15th day respectively.

从1日龄北京鸭胸腺细胞免疫的兔抗血清经适当吸收后,与鸭脑无交叉反应。反之,用鸭脑匀浆免疫的兔抗血清也不与鸭胸腺细胞起交叉反应,初步结果表明鸭脑与胸腺细胞上无共同抗原。该抗血清与鸭哈德尔氏腺细胞不起反应。抗鸭胸腺血清与鸭、来杭鸡与日本鹌鹑的胸腺细胞起交叉反应,但与鸽、小鼠、豚鼠的胸腺细胞不起反应表明是针对部分禽类胸腺细胞上的共同抗原决定簇。就个体发育中的鸭胚胸腺和脾细胞上的分布进行研究的结果表明该抗原最早出现在14天的鸭胚胸腺细胞和15天的鸭胚脾细胞上。

 
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