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glutamine treatment
相关语句
  谷氨酰胺治疗
     Methods 50 male Wistar rats were randomly divided into three groups:control(SL,n=10),obstructive jaundice group(OJ,n=20) and glutamine treatment group(TG,n=20).
     方法:健康雄性Wistar大鼠50只,随机分成空白对照组(SL,n=10)、阻塞性黄疸组(OJ,n=20)和谷氨酰胺治疗组(TG,n=20)。
短句来源
     [Methods] Fifty male wistar rats were randomly divided into three groups: control group(n=10)、obstructive jaundice group(n=20) and glutamine treatment group(n=20).
     [方法]健康雄性Wistar大鼠50只,随机分成空白对照组(SL,n=10)、阻塞性黄疸组(OJ,n=20)和谷氨酰胺治疗组(TG,n=20)。
短句来源
     Methods Fifty male Wistar rats were randomly divided into three groups: Control group (n=10), obstructive jaundice group (n=20) and glutamine treatment group (n=20).
     方法健康雄性Wistar大鼠50只,按随机数字表随机分成空白对照组(n=10)、阻塞性黄疸组(n=20)和谷氨酰胺治疗组(n=20)。
短句来源
     METHODS:39 severe burn patients(total burn surface areas 30%~60%,full thickness burn areas 20%~50%) were randomly divided into two groups:control group(C group,19 patients) and glutamine treatment group(GLN group,20 patients).
     方法 :采用随机双盲对照法 ,将烧伤总面积在30 %~60 %、Ⅲ°烧伤面积在20 %~50 %的39例患者随机分为谷氨酰胺治疗组 (20例 )和安慰剂对照组 (19例 )。
短句来源
     Methods:39 severe burn patients (total burn surface area was 30%~60%,full thickness burns area was 10%~30%) were randomly divided into two groups:control group(C group,19 patients) and glutamine treatment group (Gln group,20 patients).
     方法 :采用随机双盲对照法 ,将烧伤总面积在 30 %~ 6 0 %、三度烧伤面积在 10 %~ 30 %的 39例病人 ,随机分为谷氨酰胺治疗组 (Gln组 2 0例 )和安慰剂对照组 (C组 19例 )。
短句来源
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  谷氨酰胺
     Methods 50 male Wistar rats were randomly divided into three groups:control(SL,n=10),obstructive jaundice group(OJ,n=20) and glutamine treatment group(TG,n=20).
     方法:健康雄性Wistar大鼠50只,随机分成空白对照组(SL,n=10)、阻塞性黄疸组(OJ,n=20)和谷氨酰胺治疗组(TG,n=20)。
短句来源
     [Methods] Fifty male wistar rats were randomly divided into three groups: control group(n=10)、obstructive jaundice group(n=20) and glutamine treatment group(n=20).
     [方法]健康雄性Wistar大鼠50只,随机分成空白对照组(SL,n=10)、阻塞性黄疸组(OJ,n=20)和谷氨酰胺治疗组(TG,n=20)。
短句来源
     Methods Fifty male Wistar rats were randomly divided into three groups: Control group (n=10), obstructive jaundice group (n=20) and glutamine treatment group (n=20).
     方法健康雄性Wistar大鼠50只,按随机数字表随机分成空白对照组(n=10)、阻塞性黄疸组(n=20)和谷氨酰胺治疗组(n=20)。
短句来源
     METHODS:39 severe burn patients(total burn surface areas 30%~60%,full thickness burn areas 20%~50%) were randomly divided into two groups:control group(C group,19 patients) and glutamine treatment group(GLN group,20 patients).
     方法 :采用随机双盲对照法 ,将烧伤总面积在30 %~60 %、Ⅲ°烧伤面积在20 %~50 %的39例患者随机分为谷氨酰胺治疗组 (20例 )和安慰剂对照组 (19例 )。
短句来源
     Methods:39 severe burn patients (total burn surface area was 30%~60%,full thickness burns area was 10%~30%) were randomly divided into two groups:control group(C group,19 patients) and glutamine treatment group (Gln group,20 patients).
     方法 :采用随机双盲对照法 ,将烧伤总面积在 30 %~ 6 0 %、三度烧伤面积在 10 %~ 30 %的 39例病人 ,随机分为谷氨酰胺治疗组 (Gln组 2 0例 )和安慰剂对照组 (C组 19例 )。
短句来源
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  “glutamine treatment”译为未确定词的双语例句
     Methods Forty-two patients were randomly divided into 2 groups,one was the control group,the other was the glutamine treatment group(glutamine 100 mg/d for 7 days).
     方法42例患者随机分成两组(对照组和Gln组),Gln组进行Gln治疗(100 mL/d,共7 d)。
短句来源
     The ratio of intestinal dysfunction in the glutamine treatment group(4.8%)was significantly lower compared with that in the control group(28.6%,P<0.05).
     肠功能不全的发生率Gln组为4.8%,显著低于对照组(28.6%,P<0.05)。
短句来源
     The albumin level,the grip strength and the GSH level in the glutamine treatment group after glutamine administration was very significantly higher than that before treatment(P<0.01),and there were not significant changes in the control group for the body weight,the GSH level,and the grip strength (P>0.05).
     白蛋白、握力和GSH Gln组治疗后非常显著高于治疗前(P<0.01);
短句来源
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  glutamine treatment
Glutamine treatment was associated with decreased MDA levels and caspase-3 activity and increased GSH levels in the colinic and pancreatic tissue.
      
Liver biopsies from group III displayed typical changes of large duct obstruction that significantly improved after glutamine treatment, with decreased ductular proliferation.
      
We have used cytohistochemistry and transmission electron microscopy to study arm resorption in competent larvae of metamorphosing sea urchins, Hemicentrotus pulcherrimus, induced to metamorphose by L-glutamine treatment.
      
thaliana were determined as a control of the physiological status of the plants and remained unaffected by the glutamine treatment.
      
Improved long-term survival has been reported, which makes glutamine treatment one of the very few therapeutic strategies that improves outcome in intensive care.
      
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Objective To study the effect of glutamine on protein metabolism in severe burned patients. Methods Thirty nine severe burn patients with total burn surface area of 30%~60% and full thickness burn area of 20%~50% were randomly divided into 2 groups: control (C, 19 patients) and glutamine treatment group (GLN group, 20 patients). The former were give placebo 0 5 g·kg -1 ·d -1 for 7 d and the later received glutamine granules in a same way. The concentrations of plasma glutamine...

Objective To study the effect of glutamine on protein metabolism in severe burned patients. Methods Thirty nine severe burn patients with total burn surface area of 30%~60% and full thickness burn area of 20%~50% were randomly divided into 2 groups: control (C, 19 patients) and glutamine treatment group (GLN group, 20 patients). The former were give placebo 0 5 g·kg -1 ·d -1 for 7 d and the later received glutamine granules in a same way. The concentrations of plasma glutamine and proteins and urine nitrogen were determined. Wound healing rate 30 d after hospitalization and hospital duration were recorded. Results After 7 d of medication, the plasma concentrations of glutamine, prealbumin and transferrin were significant higher in the patients of GLN group than them before medication and those of C group ( P <0 01), and total protein and albumin concentrations were obviously higher in GLN group than in them before the treatment ( P <0 01), but had no difference with C group. On the other hand, the content of urinenitrogen was lower in GLN group than in C group. In addition, the wound healing became faster and hospital duration was shorter in GLN group than C group ( P <0.01). Conclusion Taking glutamine could promote protein synthesis, abate protein decompose, increase wound healing rate and reduce hospital duration obviously in burned patients.

目的 观察严重烧伤患者蛋白代谢的变化及口服谷氨酰胺对其的影响。方法 采用随机对照双盲试验 ,将烧伤总面积在 30 %~ 60 % ,Ⅲ度烧伤面积在 2 0 %~ 50 %的 39例患者随机分为谷氨酰胺治疗组 (GLN组 ,2 0例 )和安慰剂对照组 (C组 ,1 9例 )。GLN组每日服用谷氨酰胺颗粒剂 0 5g/kg。C组服用同等剂量的安慰剂 ,疗程为 7d。检测用药前后两组病人血中谷氨酰胺浓度、血浆蛋白含量、尿氮排量 ,并记录患者的一般情况及 30d创面愈合率和住院天数。结果GLN组病人用药 7d后 ,血浆谷氨酰胺、前白蛋白及转铁蛋白含量均显著高于用药前和C组 (P <0 0 1 ) ,血浆总蛋白、白蛋白明显高于用药前 ,但与C组相比无显著性差异 (P>0 0 5)。而GLN组的尿氮排量明显低于C组 ,且 30d创面愈合率和住院时间均优于C组。结论 服用谷氨酰胺能显著提高严重烧伤患者血中谷氨酰胺水平 ,促进机体蛋白合成 ,减少蛋白分解 ,提高 30d创面愈合率 ,缩短住院时间

Objectives:To study the protection effect of glutamine on intestinal mucosal barrier function in severe burned patients. Methods:39 severe burn patients (total burn surface area was 30%~60%,full thickness burns area was 10%~30%) were randomly divided into two groups:control group(C group,19 patients) and glutamine treatment group (Gln group,20 patients).Gln group patients had been given glutamine granules 0.5 g/kg daily for 7 days, and C group had been given same weight placebo for 7 days.The plasma...

Objectives:To study the protection effect of glutamine on intestinal mucosal barrier function in severe burned patients. Methods:39 severe burn patients (total burn surface area was 30%~60%,full thickness burns area was 10%~30%) were randomly divided into two groups:control group(C group,19 patients) and glutamine treatment group (Gln group,20 patients).Gln group patients had been given glutamine granules 0.5 g/kg daily for 7 days, and C group had been given same weight placebo for 7 days.The plasma glutamine concentration,the activity of diamine oxidase(DAO) and intestinal mucosal permeability were determined,wound healing rate of burn area was observed,and then hospital stay was recorded. Results:After 7 days of oral glutamine intake, plasma glutamine concentration in Gln group was significantly higher than that in C group( P <0.01).On the other hand,the degree of intestine damage and intestinal mucosa permeability in Gln group were lower than those in C group.In addition,the wound healing was faster and hospital stay days was shorter than in C group( P <0.01). Conclusions:Taking L glutamine could abate the degree of intestine injury,lessen intestinal mucosal permeability,ameliorate wound healing rate and reduce hospital stay obviously.

目的 :观察严重烧伤病人肠粘膜屏障功能的变化及口服谷氨酰胺颗粒剂对它的影响。 方法 :采用随机双盲对照法 ,将烧伤总面积在 30 %~ 6 0 %、三度烧伤面积在 10 %~ 30 %的 39例病人 ,随机分为谷氨酰胺治疗组 (Gln组 2 0例 )和安慰剂对照组 (C组 19例 )。Gln组每天服用谷氨酰胺颗粒剂 0 .5 g/kg。C组服用同等剂量的安慰剂 ,疗程为 7天。检测用药前后两组病人血中谷氨酰胺浓度、二胺氧化酶 (DAO)活性、内毒素含量及肠粘膜通透性的变化 ,并记录一般情况和住院日。 结果 :Gln组病人用药 7天后 ,血中谷氨酰胺含量明显高于C组 (P <0 .0 1) ,而血浆DAO活性、内毒素含量及肠粘膜通透性均显著低于C组 (P <0 .0 1) ,住院日显著短于C组。 结论 :服用谷氨酰胺颗粒剂能显著提高严重烧伤病人血中谷氨酰胺水平 ,减轻伤后肠道受损程度 ,保护肠粘膜屏障 ,并有助于缩短住院日。

OBJECTIVE:To evaluate the clinical therapeutic effect of L-glutamine granules on intestinal damage of severe burn patients and the safty of the drug METHODS:Thirty-nine severe burn patients were randomly divided into two groups:control group(C group,nineteen patients)and L-glutamine treatment group(GLN group,twenty patients) GLN group patients were given L-glutamine in a dose of 30g per day for 7 days,and C group patients were given the same dosage of placebo for 7 days The plasma L-glutamine...

OBJECTIVE:To evaluate the clinical therapeutic effect of L-glutamine granules on intestinal damage of severe burn patients and the safty of the drug METHODS:Thirty-nine severe burn patients were randomly divided into two groups:control group(C group,nineteen patients)and L-glutamine treatment group(GLN group,twenty patients) GLN group patients were given L-glutamine in a dose of 30g per day for 7 days,and C group patients were given the same dosage of placebo for 7 days The plasma L-glutamine concentration,the degree of intestinal mucosa damage,blood biochemistry and complication were observed and wound healing rate of burn area was determined,then the length of hospital stay was recorded RESULTS:After 7 days of taking L-glutamine orally,plasma L-glutamine concentration in GLN group was significant higher than that in C group(P<0 01) The degree of intestine damage and intestinal mucosal permeability in GLN group were lower than those in C group In addition,the wound healing rate was faster and the length of hospital stay was shorter in GLN group than those in C group CONCLUSION:Administration of L-glutamine could abate the degree of intestine damage obviously,lessen intestinal mucosal permeability,ameliorate wound healing rate and reduce the length of hospital stay

目的 :评价谷氨酰胺颗粒剂对严重烧伤后肠道损害的疗效及安全性。方法 :采用随机双盲对照法 ,将受试患者分为治疗组 (20例 )和对照组 (19例 ) ,治疗组口服谷氨酰胺颗粒剂30g/天 ,每天3次 ,对照组口服同等剂量的安慰剂。观察两组患者血浆谷氨酰胺含量、肠粘膜受损程度、肝肾功能及并发症等 ,并比较患者创面愈合情况和住院天数。结果 :治疗组患者用药7天后 ,血中谷氨酰胺含量分别较用药前和对照组升高了37 87 %和37 86 % (P<0 01)。治疗组与对照组相比 ,一般情况较好 ,肠道损害程度明显减轻 ,肠粘膜通透性降低 ,创面愈合较快 ,住院天数明显缩短。所有受试者无1例因不良反应而停药 ,无1例死亡。结论 :服用谷氨酰胺颗粒剂能显著减轻烧伤后患者肠道受损程度 ,保护肠粘膜屏障 ,促进创面愈合 ,且无明显不良反应。

 
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