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morphogenetic protein
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  形态发生蛋白
     The Q249R mutation(A746G) in bone morphogenetic protein receptor-ⅠB(BMPR-ⅠB) is associated with the high prolificacy of Booroola Merino sheep.
     骨形态发生蛋白受体ⅠB(BMPR-ⅠB)的Q249R(A746G)突变使Booroola Merino绵羊的繁殖性能提高。
短句来源
     Objective To study the expression of BMP(bone morphogenetic protein)-2,-3,-6,and-12 in osteosarcoma cell lines.
     目的研究骨形态发生蛋白(bone morphogenetic protein,BMP)-2、-3、-6和-12在骨肉瘤细胞株中的表达,为下一步研究BMPs在骨肉瘤发生发展中的作用奠定基础。
短句来源
     The method of PCR-SSCP to detect sheep inhibin a (INHA) gene、 bone morphogenetic protein 4(BMP4) gene and bone morphogenetic protein 7 (BMP7) gene mutations were established in this study.
     本研究建立了检测小尾寒羊抑制素α(inhibin α,INHA)、骨形态发生蛋白4(BMP4)和骨形态发生蛋白7(BMP7)三个基因的单核苷酸突变的PCR-SSCP方法。
短句来源
     Studieson Expressionof TGF β_1and bFGF during OsteogenesisInduced by Bone Morphogenetic Protein
     骨形态发生蛋白诱骨发生过程中TGF-β_1和bFGF的表达
短句来源
     In the study, deletion of growth differentiation factor 9 gene and bone morphogenetic protein 15 gene were served as examples for establishing these methods.
     并以牛生长分化因子9(growth differentiation factor 9,GDF9)基因和骨形态发生蛋白15(bone morphogenetic protein 15,BMP15)基因的缺失突变基因型的检测为例,对两种方法进行了探讨。
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  形成蛋白
     Objective To investigate the differentiation of the adipose-derived adult stem cell (ADASC) induced by the recombinant adenovirus's containing fibers derived from B-group serotype 35 (rAd5/F35)-mediated human bone morphogenetic protein 7 (hBMP-7) gene and to explore a new cell source for the bone tissue engineering. Methods The hBMP-7 gene was amplified with the pcDNA1.1/AMP-hBMP-7 plasmid as a formwork.
     目的在体外运用人骨形成蛋白7(human bone morphogenetic protein7,hBMP-7)基因重组35型腺病毒(recombinant adenovirus's containing fibers derived from B-group serotype35,rAd5/F35)诱导大鼠脂肪源性干细胞(adipose-derived adult stem cell,ADASC)向成骨细胞定向分化,为骨组织工程探索新的细胞来源。
短句来源
     Transforming Growth Factor β1 (TGFβ1) and Bone Morphogenetic Protein 2 (BMP2) Induce Odontoblast-like Cell Differentiation in vitro.
     转化生长因子β1(TGF-β1)和骨形成蛋白2(BMP2)体外联合诱导成牙本质细胞样细胞分化
短句来源
     Cloning of partial cDNA of human bone morphogenetic protein 3 (hBMP-3) gene by RT-PCR
     人骨形成蛋白3基因cDNA部分序列的RT-PCR克隆
短句来源
     The Experimental Study of Bone Formation Induced by NIH3T3 Cells Transfected with Bone Morphogenetic Protein 2 Gene
     骨形成蛋白2基因转染NIH3T3细胞诱导成骨的实验研究
     Objective:To investigate the effect of recombinant human bone morphogenetic protein(rhBMP-2), insulin-like growth factor -I(IGF-I) on rabbit osteoblastic cell proliferation.
     目的:研究人重组骨形成蛋白(recombinant human bone morphogenetic protein,rhBMP),胰岛素样生长因子-1(insulin-like growth factor-1,IGF-I) 单独及联合应用对兔成骨细胞增殖的影响。
短句来源
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  形态蛋白
     Experimental Study of Bone Morphogenetic Protein (BMP) in Conditioned Medium of Human Osteosarcoma Cell
     人骨肉瘤原代细胞条件培养基中骨形态蛋白(BMP)的实验研究
短句来源
     Conclusion Combination of bone morphogenetic protein complex with GTR was more effective than GTR only or OFD in the repair of periodontal bone defects.
     结论 骨形态蛋白复合物联合GTR技术修复牙周骨缺损 ,与传统的GTR术和牙周翻瓣术相比 ,更能有效促进牙周骨组织再生与修复。
短句来源
     Conclusions APBSC has an obvious osteogenic effect on the induction of bone morphogenetic protein derived from DB. APBSC/DB is superior to DB alone in the curative effect of repairing segmental bony defects.
     结论 APBSC在DB的骨形态蛋白诱导下具有明显的成骨作用 ,因此APBSC/DB复合移植治疗骨缺损的疗效优于单纯DB移植
短句来源
     Extraction, Purification and Identification of Bone Morphogenetic Protein in Conditioned Medium of Osteosarcoma Cell (MG-63)
     骨肉瘤细胞(MG-63)条件培养基中骨形态蛋白(BMP)的实验研究——BMP的分离、纯化、鉴定(英文)
短句来源
     Objective To observe the effect and influence of recombinant human bone morphogenetic protein 2 (rhBMP 2) on osteoporotic fracture healing in the rat and to expect to provide an effective therapy for osteoporotic fracture.
     目的观察基因重组人骨形态蛋白-2(rhBMP-2)对骨质疏松性骨折愈合的作用与影响。
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  “morphogenetic protein”译为未确定词的双语例句
     Inductive effect of bovinc bone morphogenetic protein on human dental pulp tissue in vitro
     Inductive effect of bovinc bone morphogenetic protein on human dental pulp tissue in vitro
短句来源
     AN IMMUNOCYTOCHEMICAL STUDY OF BONE MORPHOGENETIC PROTEIN IN EXPERIMENTAL FRACTURE HEALING OF THE RABBIT MANDIBLE
     AN IMMUNOCYTOCHEMICAL STUDY OF BONE MORPHOGENETIC PROTEIN IN EXPERIMENTAL FRACTURE HEALING OF THE RABBIT MANDIBLE
短句来源
     Immunohistochemical demonstration of transforming growth factor-β and bone morphogenetic protein in salivary gland tumors
     Immunohistochemical demonstration of transforming growth factor-β and bone morphogenetic protein in salivary gland tumors
短句来源
     SPECIFIC BINDING OF HUMAN BONE MORPHOGENETIC PROTEIN (2A) WITH MOUSE OSTEOBLASTIC CELLS
     SPECIFIC BINDING OF HUMAN BONEMORPHOGENETIC PROTEIN (2A) WITH MOUSEOSTEOBLASTIC CELLS
短句来源
     The Comparison of Expression of Bone Morphogenetic Protein 2(BMP-2)in COS Cells with That in B16F1 Cells
     骨多形性蛋白2cDNA在COS细胞和B16F1细胞中的表达差异
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  morphogenetic protein
As revealed more than ten years ago in experiments with Xenopus embryos, the major role in neural induction is played by suppression of the bone morphogenetic protein (BMP) signaling cascade in neural cell precursors.
      
However, bone morphogenetic protein-2 (BMP-2) and vascular endothelial growth factor (VEGF), though their IEPs are higher than 7.0, were sorbed to the acidic gelatin hydrogel to a smaller extent than the two other growth factors.
      
Ewing's sarcoma can express bone morphogenetic protein
      
Bone morphogenetic protein and activin signaling in colorectal cancer
      
The roles in colon cancer pathogenesis of the transforming growth factor family members bone morphogenetic protein (BMP) and activin have only recently been studied but are increasingly recognized as key.
      
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Using decalcified bone matrix (DBM), bone matrix gelatin (BMG) and Undecalcified bone matrix(UDBM), the capacity of bone induction -was investigated respectively.the experiments were done on the adult rat skulls on which trephine defects of 8 mm in diameter were made, the implants were in form of discs of same size as the defects. BMG was found having the best bone induction capacity, while DBM the next, from the histo-pathological observation, it was suggested that during the process of resorption of BMG and...

Using decalcified bone matrix (DBM), bone matrix gelatin (BMG) and Undecalcified bone matrix(UDBM), the capacity of bone induction -was investigated respectively.the experiments were done on the adult rat skulls on which trephine defects of 8 mm in diameter were made, the implants were in form of discs of same size as the defects. BMG was found having the best bone induction capacity, while DBM the next, from the histo-pathological observation, it was suggested that during the process of resorption of BMG and DBM, bone morphogenetic Protein (BMP) was released by diffusion, which induced mesenchymal cells originating from the dura mater to differentiate into osteoblasts and form new bone repairing the bone defects

本文报告一组促进骨折愈合的实验结果,所用试验材料为骨基质明胶片、脱钙骨片和不脱钙骨片。在大鼠颅顶骨上制成8mm直径的圆形骨缺损,作为骨折不连接的动物模型。在此骨缺损内分别植入上述三种材料。结果表明它们都有不同程度的骨诱导作用,其中骨基质明胶片的骨诱导作用最强,脱钙骨片次之。病理组织学观察显示植入片在吸收的同时释放出骨形成性蛋白,诱发来源于硬脑膜的间充质细胞分化为成骨细胞,形成新生骨组织,修复骨缺损

Human bone morphogenetic protein ( hBMP ) was extracted and purified from human bone matrix by means of a conbination of differential precipitation, ultr-afiltration, and hydroxyapatite chromatography. The molecular weight of hBMP is 17000 U. 147 C3H mice were used in the experiment to identify the activity of hBMP. Osteoinduction rate of purified hBMP was 100%.

本实验采用差示沉积、超滤及羟基磷灰石柱层析法,提取和纯化了人骨基质内骨形态形成蛋白,得到纯化的人骨形态形成蛋白,分子量为17000U(约17000道尔顿).以C_3H小鼠147只为实验动物,纯化的骨形态形成蛋白的诱导成骨率为100%。

Sheep bone morphogenetic protein (sBMP) was chemically extracted from demineralized and gelatinized cortical bone by means of a CaCl_2-urea solvent, sBMP was isolated in quantity of 1,250mg/kg fresh bone. 5mg of the isolated protein implanted in muscle pouches of rats induced perivascular mesenchymal connective tissue cells which differentiated into cartilage by the 7th day and calcifying new bone by 21st day.

本文报道羊成骨蛋白(sBMP)的提取方法及其生物学活性试验结果。小鼠大腿肌肉内种植5mg sBMP后7天,局部形成软骨组织,14天形成骨样组织,28天出现板层骨结构。sBMP的骨诱导作用主要在于促使纤维母样间充质细胞定向分化成为软骨细胞和骨母细胞进而形成骨组织。文内还讨论了sBMP提取的有关问题及其对靶细胞作用的机制等问题。

 
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