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direct powder compression
相关语句
  粉末直接压片
     (2) drug release from HPMC hydrocolloid matrices prepared by wet granulation method with 1% HPMC K4M in 50% ethanol was comparable to those prepared by direct powder compression procedure;
     (2 )对于 HPMC亲水凝胶骨架片 ,用含1% HPMC K4 M的 5 0 %乙醇湿法制粒的效果与粉末直接压片相当 ;
短句来源
     Study on direct powder compression of aspirin tablet
     阿司匹林片剂粉末直接压片新工艺研究
短句来源
     Study on the technique of direct powder compression of Captopril Tablets
     卡托普利全粉末直接压片工艺研究
短句来源
     Preparation of Dosmalfate Dispersible Tablets by Direct Powder Compression Technique
     粉末直接压片法制备多司马酯分散片
短句来源
     Study on direct powder compression of Naoan tablet
     脑安片粉末直接压片新工艺研究
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  直接压片
     (2) drug release from HPMC hydrocolloid matrices prepared by wet granulation method with 1% HPMC K4M in 50% ethanol was comparable to those prepared by direct powder compression procedure;
     (2 )对于 HPMC亲水凝胶骨架片 ,用含1% HPMC K4 M的 5 0 %乙醇湿法制粒的效果与粉末直接压片相当 ;
短句来源
     Results: An ideal tablet model was obtained by direct powder compression. The release rate in vitro was about 2 5% at 1 hour and more than 90% at 12 hours.
     结果:直接压片可得到理想的片型,缓释片体外释药1 h释放度为25 0%左右,12 h在90. 0%以上。
短句来源
     Study on direct powder compression of aspirin tablet
     阿司匹林片剂粉末直接压片新工艺研究
短句来源
     Study on the technique of direct powder compression of Captopril Tablets
     卡托普利全粉末直接压片工艺研究
短句来源
     Preparation of Dosmalfate Dispersible Tablets by Direct Powder Compression Technique
     粉末直接压片法制备多司马酯分散片
短句来源
更多       
  粉末直接压片法
     Conclusion: The technique of direct powder compression is simple and useful, and the prep ared sustained-release tablets release well during 12 hours in vitro.
     结论:粉末直接压片法工艺简单可行,骨架片体外释放效果良好。
短句来源
  “direct powder compression”译为未确定词的双语例句
     Naoan tablets of direct powder compression compared with wet method manufacture pellet,product qualified rate enhances 30%.
     新工艺制备的脑安片比湿法制粒老工艺制备的脑安片一次合格率提高30%.
短句来源
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The effects of preparation parameters on the release of hydromorphone hydrochloride from six various of matrices were investigated. The results showed that: (1) combined use of HPMC with octadecanol or EC could remarkably decrease the effect of compression force on drug release; (2) drug release from HPMC hydrocolloid matrices prepared by wet granulation method with 1% HPMC K4M in 50% ethanol was comparable to those prepared by direct powder compression procedure; drug release from combined HPMC octadecanol...

The effects of preparation parameters on the release of hydromorphone hydrochloride from six various of matrices were investigated. The results showed that: (1) combined use of HPMC with octadecanol or EC could remarkably decrease the effect of compression force on drug release; (2) drug release from HPMC hydrocolloid matrices prepared by wet granulation method with 1% HPMC K4M in 50% ethanol was comparable to those prepared by direct powder compression procedure; drug release from combined HPMC octadecanol matrices prepared by wet granulation method was faster than those prepared by melt granulation method; (3) drug release from combined HPMC octadecanol matrices varied with tablet diameter or/and weight less than those from combined HPMC CMCNa octadecanol matrices; (4) film coating, granule size and scale up of process had little effect on drug release from combined HPMC octadecanol matrices.

以盐酸氢吗啡酮为模型药物 ,制备了 6种不同类型的骨架片 ,研究了工艺参数对骨架片释放行为的影响。结果表明 :(1) HPMC与十八醇或 EC合用能明显减小压片压力对释放的影响 ;(2 )对于 HPMC亲水凝胶骨架片 ,用含1% HPMC K4 M的 5 0 %乙醇湿法制粒的效果与粉末直接压片相当 ;对于 HPMC-十八醇混合骨架片 ,湿法制粒的释药快于熔融制粒法 ;(3) HPMC-十八醇混合骨架片释放受片径或 (和 )片重改变的影响小于 HPMC- CMC- Na-十八醇混合骨架片 ;(4)包薄膜衣、制粒大小及工艺放大对 HPMC-十八醇混合骨架片的释放基本无影响。

The properties such as granularity, fluidity and swelling capacity of domestic and imported microcrystalline cellulose (MCC) PH101 were investigated and compared. The disintegration and dissolution of metoprolol tartrate tablets and atenolol tablets prepared with six brands of MCC respectively and by direct powder compression method were determined. The results indicated that the profiles of some domestic MCC were comparable to the imported ones.

比较了 6种国产和进口微晶纤维素 PH10 1的粒径、流动性和溶胀性等 ,采用直接压片法 ,考察了两种不同模型药物压成片剂的崩解度和溶出度。结果表明 ,部分国产微晶纤维素的质量已达到或优于进口产品。

Objective:To establish a new method to make aspirin tablets by directly squashing aspirin and excipients powder.Methods:Choose new excipients which can be rapidly released,directly squashed and have good fluidity,mix them with aspirin powder and directly squash the mixed powder to produce aspirin tablets.Under stress test,accelerated test,room temperature environment,the following aspirin tablets' properties were assessed:appearance,aspirin's content, dissolution speed and salicylic acid's content.Result and...

Objective:To establish a new method to make aspirin tablets by directly squashing aspirin and excipients powder.Methods:Choose new excipients which can be rapidly released,directly squashed and have good fluidity,mix them with aspirin powder and directly squash the mixed powder to produce aspirin tablets.Under stress test,accelerated test,room temperature environment,the following aspirin tablets' properties were assessed:appearance,aspirin's content, dissolution speed and salicylic acid's content.Result and Conclusion:Aspirin tablets have good stability, their properties are correspondent with the requirements of Chinese Pharmcopeia 2000.The new direct powder compression method would not cause aspirin degradation.

目的 :建立阿司匹林粉末直接压片的新工艺。方法 :使用新型的速释直接压片辅料 ,筛选出可压性和流动性均好的稀释剂 ,建立粉末直接压片的新工艺。经影响因素试验、加速试验及室温贮存考察 ,检测制备的阿司匹林片的性状、溶出度、含量及色谱检查降解产物游离水杨酸。结果 :本工艺制备的阿司匹林片稳定性良好 ,其性状、溶出度、含量及游离水杨酸均符合 2 0 0 0版药典规定。结论 :粉末直接压片新工艺不会引起阿司匹林降解

 
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