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preprandial glucose
相关语句
  餐前血糖
     (3) The relative contribution of postprandial glucose to overall glucose levels in the T2DM group was significantly higher than that of the NGR group (18.1%±0.8% vs 8.0%±0.7%, P<0.01), but both were significantly lower than those of preprandial glucose.
     (4)T2DM组餐后血糖对总体日内血糖的贡献百分比显著高于NGR组(18·1%±0·8%比8·0%±0·7%,P<0·01),但均显著低于其餐前血糖(P<0·01)。
短句来源
  “preprandial glucose”译为未确定词的双语例句
     After being adjusted by preprandial glucose, the partial correlation of HbA1c and IAUC disappeared (before r=0.29, P=0.03, after P=0.05).
     PPGE与IAUC呈显著正相关(r=0·93,P<0·01)。
短句来源
     Through 12 weeks' observation,comparing the two groups in fasting Blood glucose(FBG)、postprandial glucose(PPG)、preprandial glucose and HbA1c.
     应用12周,观察两组的空腹血糖、餐后血糖、中餐前血糖及糖化血红蛋白在治疗前后的变化。
短句来源
  相似匹配句对
     glucose 3;
     葡萄糖 ,3;
短句来源
     The nonreduced end is glucose.
     末端残基为Glc。
短句来源
     Comparied with the preprandial levels, the postprandial levels of insulin and glucose as well as SS were higher(P<0.01) in PEM group, the same as in control group.
     两组餐后与餐前比较,胰岛素、胰高血糖素、SS、胰岛素/胰高血糖素比值和血糖水平均明显升高(P均<0.01)。
短句来源
     However,the level of SS was higher(P<0.01),and the level of glucose significantly lower(P<0.01) in preprandial comparison and was significantly higher in postprandial comparison.
     血糖水平,餐前明显降低(P均<0.01); 餐后明显升高(P均<0.01)。
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  preprandial glucose
The measures of glycaemia that are initially targeted on a day-to-day basis are the fasting and preprandial glucose levels.
      
A preprandial glucose target of 90 to 150 mg per decili ter is recommended for most patients.
      


Objective To study the features of postprandial glucose state in individuals with normal glucose regulation (NGR) and type 2 diabetes (T2DM) and the relations between hemoglobin A1c (HbA1c) and postprandial glucose in T2DM.Methods 41 NGR individuals and 60 newly diagnosed T2DM patients without previous management in Shanghai were measured by continuous glucose monitoring system for 3 days. The postprandial glucose spike (PGS), time to PGS (△t), postprandial glucose excursion (PPGE), duration of postprandial...

Objective To study the features of postprandial glucose state in individuals with normal glucose regulation (NGR) and type 2 diabetes (T2DM) and the relations between hemoglobin A1c (HbA1c) and postprandial glucose in T2DM.Methods 41 NGR individuals and 60 newly diagnosed T2DM patients without previous management in Shanghai were measured by continuous glucose monitoring system for 3 days. The postprandial glucose spike (PGS), time to PGS (△t), postprandial glucose excursion (PPGE), duration of postprandial glucose (DUR) and incremental area under the curve of postprandial glucose (IAUC) were calculated in each individual.Results (1) The levels of PGS and △t in the T2DM group were significantly higher than those of the NGR group (all P<0.01). The levels of PPGE, DUR and IAUC of the T2DM group were 5.87 mmol/L±0.19 mmol/L, 14.1 h±0.3 h and 2.04 mmol·L~ -1 ·d±0.09 mmol·L~ -1 ·d respectively, all significantly higher than those of the NGR group (2.10 mmol/L±0.12 mmol/L, 8.3 h±0.4 h and 0.43 mmol·L~ -1 ·d±0.03 mmol·L~ -1 ·d respectively, all P<0.01). The breakfast had higher PGS and lower △t than those of lunch and dinner in the T2DM group (both P<0.01). The PPGE was arranged from high to low in the order of breakfast, dinner and lunch. The highest IAUC appeared during dinner.(2) There was a significantly correlation between PPGE and IAUC (r=0.93, P<0.01) in the T2DM group. After being adjusted by preprandial glucose, the partial correlation of HbA1c and IAUC disappeared (before r=0.29, P=0.03, after P=0.05).(3) The relative contribution of postprandial glucose to overall glucose levels in the T2DM group was significantly higher than that of the NGR group (18.1%±0.8% vs 8.0%±0.7%, P<0.01), but both were significantly lower than those of preprandial glucose.(4) Relative contribution of postprandial hyperglycemia to overall diurnal hyperglycemia decreased progressively from the lowest to the highest quarter of HbA1c. By contrast, the relative contribution of preprandial hyperglycemia showed a significant increase with increasing levels of HbA1c. Postprandial hyperglycemia played a major role when the HbA1c level below 7.5% (P<0.05). Conclusion (1) The features of postprandial glucose state in T2DM is representative in the delay of PGS and excessive glucose excursion for a long time after the ingestion of a meal.(2) HbA1c can′t reflect postprandial glucose excursions. PPGE can be used as a simple clinic index to evaluate the amplitude of postprandial glucose excursions.(3) Postprandial glucose excursions play a major role in T2DM suffering from mild or moderate hyperglycemia. The present results suggest that postprandial hyperglycemia is an important target for intervention when T2DM patients are approaching the ideal glycemic control.

目的探讨正常糖调节(NGR)及2型糖尿病(T2DM)个体餐后血糖状态的特征以及T2DM患者餐前、餐后血糖与糖化血红蛋白(HbA1c)的关系。方法采用动态血糖监测系统对上海地区41例NGR及60例新诊断T2DM个体进行连续3d的血糖监测,分析比较餐后血糖峰值与达峰时间,以及餐后血糖漂移的幅度(PPGE)、时间和曲线下面积增值(IAUC)。结果(1)三餐后血糖峰值、达峰时间及PPGE在T2DM组(早餐16·45mmol/L±0·43mmol/L、93·1min±4·7min、6·84mmol/L±0·28mmol/L,中餐14·75mmol/L±0·50mmol/L、107·4min±6·5min、4·93mmol/L±0·31mmol/L,晚餐14·91mmol/L±0·45mmol/L、109·3min±4·9min、5·84mmol/L±0·28mmol/L)显著高于NGR组(早餐6·90mmol/L±0·21mmol/L、40·8min±2·9min、2·02±0·17mmol/L,中餐6·74mmol/L±0·16mmol/L、43·7min±3·1min、2·03±0·12mmol/L,晚餐6·94m...

目的探讨正常糖调节(NGR)及2型糖尿病(T2DM)个体餐后血糖状态的特征以及T2DM患者餐前、餐后血糖与糖化血红蛋白(HbA1c)的关系。方法采用动态血糖监测系统对上海地区41例NGR及60例新诊断T2DM个体进行连续3d的血糖监测,分析比较餐后血糖峰值与达峰时间,以及餐后血糖漂移的幅度(PPGE)、时间和曲线下面积增值(IAUC)。结果(1)三餐后血糖峰值、达峰时间及PPGE在T2DM组(早餐16·45mmol/L±0·43mmol/L、93·1min±4·7min、6·84mmol/L±0·28mmol/L,中餐14·75mmol/L±0·50mmol/L、107·4min±6·5min、4·93mmol/L±0·31mmol/L,晚餐14·91mmol/L±0·45mmol/L、109·3min±4·9min、5·84mmol/L±0·28mmol/L)显著高于NGR组(早餐6·90mmol/L±0·21mmol/L、40·8min±2·9min、2·02±0·17mmol/L,中餐6·74mmol/L±0·16mmol/L、43·7min±3·1min、2·03±0·12mmol/L,晚餐6·94mmol/L±0·19mmol/L、53·5min±3·8min、2·25mmol/L±0·18mmol/L,均P<0·01)。日内餐后血糖漂移时间及IAUC在T2DM组(14·1h±0·3h,2·04mmol·L-1·d±0·09mmol·L-1·d)亦显著高于NGR组(8·3h±0·4h,0·43mmol·L-1·d±0·03mmol·L-1·d,均P<0·01)。(2)T2DM组早餐后血糖较快达到尖峰(P<0·05),且峰值显著高于中、晚餐(P<0·01),PPGE从高到低的顺序分别为早、晚及中餐(P<0·05),晚餐的IAUC显著高于早、中餐(P<0·01)。(3)HbA1c与IAUC的相关性(r=0·29,P=0·03)在调整餐前血糖的因素后消失(P=0·05);PPGE与IAUC呈显著正相关(r=0·93,P<0·01)。(4)T2DM组餐后血糖对总体日内血糖的贡献百分比显著高于NGR组(18·1%±0·8%比8·0%±0·7%,P<0·01),但均显著低于其餐前血糖(P<0·01)。(5)当HbA1c<7·5%时,餐后血糖升高部分对总体日内高血糖的贡献大于餐前血糖(P<0·05),当HbA1c≥7·5%时,餐前高血糖的相对作用逐渐增加并占主要作用(P<0·01)。结论(1)T2DM患者表现为餐后血糖的过度漂移并持续较长时间,同时伴有血糖尖峰的延迟,其餐后急性高血糖状态以早餐最明显。(2)HbA1c不能反映餐后血糖的漂移变化,PPGE可作为估测餐后血糖漂移程度的简易临床参数。(3)在轻、中度高血糖的患者中,餐后高血糖起主要作用,提示血糖控制越接近达标,餐后血糖的控制越重要。

Objective To observe BIAsp30's clinical application in patients with type 2 diabetes.Methods 52 patients with type 2 diabetes using insulin were randomly divided into the treatment group(26 patients) and the control group(26 patients).The treatment group were treated with BIAsp30 and the control group were treated with BHI30 twice daily in morning and evening.Through 12 weeks' observation,comparing the two groups in fasting Blood glucose(FBG)、postprandial glucose(PPG)、preprandial glucose and HbA1c.Results...

Objective To observe BIAsp30's clinical application in patients with type 2 diabetes.Methods 52 patients with type 2 diabetes using insulin were randomly divided into the treatment group(26 patients) and the control group(26 patients).The treatment group were treated with BIAsp30 and the control group were treated with BHI30 twice daily in morning and evening.Through 12 weeks' observation,comparing the two groups in fasting Blood glucose(FBG)、postprandial glucose(PPG)、preprandial glucose and HbA1c.Results The two groups blood glucoses and HbA1c had decreased distinctly after treatment(P<0.05).The FBG and HbA1c's descendent level of the two groups had not distinct difference(P>0.05).The PPG descendent level of treatment group had distinct difference(P<0.05).Conclusion The PPG of the treatment group distinctly descend.The low glucoses' occurrence rate of the treatment group was much lower than the control group.The FBG and HbA1c also descend.BIAsp30 is more suitable for patients with type 2 diabetes,especially patients with high PPG.

目的观察诺和锐30(双时相门冬胰岛素)在2型糖尿病患者中的临床应用。方法将52例需用胰岛素的2型糖尿病患者随机分成治疗组(26例)和对照组(26例)。治疗组应用诺和锐30,对照组应用诺和灵30R,均为每日两次皮下注射。应用12周,观察两组的空腹血糖、餐后血糖、中餐前血糖及糖化血红蛋白在治疗前后的变化。结果两组的空腹血糖、餐后血糖、中餐前血糖及糖化血红蛋白较治疗前明显下降(P<0.05)。两组的空腹血糖、中餐前血糖、糖化血红蛋白下降值差异不明显(P>0.05),而餐后血糖的下降值有明显差别(P<0.05)。结论治疗组的餐后血糖有明显降低,而且低血糖发生率较低,对空腹血糖、中餐前血糖及糖化血红蛋白亦有降低,是2型糖尿病尤其以餐后血糖高为主的患者更适合应用。

 
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