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    Polarized Populations and Natural Killer Cells of T Helper Cells in Patients with Chronic Hepatitis B Virus Infection
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  patients
Genomic DNA was extracted from blood samples of healthy controls and from patients with HBV infection.
      
The immunoassay was used to check the BALP of the blood serum that was from 42 primary osteosarcoma patients.
      
The patients were followed up from five months to 49 months with an average of 24.3 months.
      
Detection of abnormal myocardial perfusion is crucial to the prognosis of patients with coronary artery disease (CAD) after they have undergone percutaneous coronary intervention (PCI).
      
For those patients with acute or total occlusion, the levels of myocardial perfusion before and after PCI were similar, as determined by IC-MCE and visually analyzed from 61 segments (P >amp;lt; 0.05).
      
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Recent studies on viral hepatitis showed that the pathogenesis and the out-come of viral hepatitis are closely related to the immunologic reactions of the patients.Since 1974 we have observed the immunologic states of normal subject, acute hepatitis, chronic hepatitis and cirrhosis with 7 different immunologic tests including those of cellular immunity, humoral immunity and auto-immunity. The results were as follows: Acute hepatitis had a relative good immunologic conditions. While that of chronic hepatitis...

Recent studies on viral hepatitis showed that the pathogenesis and the out-come of viral hepatitis are closely related to the immunologic reactions of the patients.Since 1974 we have observed the immunologic states of normal subject, acute hepatitis, chronic hepatitis and cirrhosis with 7 different immunologic tests including those of cellular immunity, humoral immunity and auto-immunity. The results were as follows: Acute hepatitis had a relative good immunologic conditions. While that of chronic hepatitis were rather complex (effect of virus, formation of antigen-antibody complex, auto immune reactions, immuno-pathologic lesions act to different extents on the mechanism and pathogenesis of chronic hepatitis.) Cirrhosis showed depression of cellular immunity and disterbances of humoral immunity.

近年来关于病毒性肝炎的研究表明,其发病机理及转归与机体的免疫反应密切相关。五年来我们应用七项免疫学检查指标(包括细胞免疫、体液免疫、自家免疫),对正常人、急性肝炎、慢性肝炎,肝硬化患者的机体免疫状态进行了观察。其结果:急性肝炎患者机体免疫状况尚好,慢性肝炎患者机体免疫情况较复杂。病毒的作用,免疫复合物的产生,自身免疫反应,免疫病理损害不同程度地参与慢性肝炎的发病;肝硬化患者是细胞免疫低下,体液免疫失调。

117 cases of psychosis patients were treated mainly with tradittonal Chinese Medicine. Among the 117 eases, the cure rate were 77.3%, and over 80% of patients attained cure in short period. 98.2% of patients attained iniprovement in total

本文总结了以中医为主治疗精神病117例的经验,治愈率77.3%,近期治愈率80%以上,总有效率98.2%。作者认为:用中药调整患者脏腑功能及消除其病理产物,用针刺激发和增强机体的抗病能力及调整中枢神经的调节功能,同时配合小剂量的西药镇静,这种综合方法安全有效,简便易行。本文是1976年的原稿,其中结合作者当时的体会就如何分型及治疗等问题仅进行了初步探讨;所附病例已俱三年以上的随访观察,患者愈后一直工作如常人,并无后遗症。

~3H-Tdr incorporation in lymphocyte transformation test (~3H-Tdr. LCT) with PHA as stimulating antigen was used to study the cellular immunity patterns in 90 cases of various types of viral hepatitis, 13 asymptomatic HBsAg carriers and 41 normal adults. The mean value of ~3H-Tdr. LCT in 18 cases of chronic active hepatitis, 13 carriers, and 5 gravis form were 86.9±9.3, 74.9±8.7 and 23.4±4.8, respectively. As compared with that of normal adults (105.5±10.2), there was a significant difference (p<0.01). The mean...

~3H-Tdr incorporation in lymphocyte transformation test (~3H-Tdr. LCT) with PHA as stimulating antigen was used to study the cellular immunity patterns in 90 cases of various types of viral hepatitis, 13 asymptomatic HBsAg carriers and 41 normal adults. The mean value of ~3H-Tdr. LCT in 18 cases of chronic active hepatitis, 13 carriers, and 5 gravis form were 86.9±9.3, 74.9±8.7 and 23.4±4.8, respectively. As compared with that of normal adults (105.5±10.2), there was a significant difference (p<0.01). The mean value of ~3H-Tdr. LCT in acute icteric form was significantly lower than that of acute anicteric form (p<0.05), and the mean value in the early stage of 5 acute icteric hepatitis was significantly lower than that of the late stage (p<0.01). 4 of these 5 were re-examined during the course of disease, 3 returned to normal level associated with a complete clinical recovery, the other one with persistent low level progressed into gravis form. 4 of the 5 gravis form died, the only survived patient was one whose ~3H-Tdr. LCT value returned to normal level. The results indicated that there was a positive correlation between the cellular immunologic response of the patient and the clinical manifestation and the outcome of the disease. When the individual was infected by the hepatitis virus, his cellular immunity was significantly inhibited. If the immunity was rapidly restored, the disease ended in recovery, whereas if the immunity was seriously inhibited, the patient could be prompted to death ultimately, and if inhibition of cellular immunity persisted or if the patient had pre-existing lowered cellular immunity, the test reaction would reveal a subnormal level for a long time, and a chronic form of hepatitis may develop. However, the mean value of lymphocyte transformation test presented no significent difference between the various types of hepatitis patients and the carriers. Though the erythrocyte rosette cycle formation test may also be used to study the immunity, it is not so sensitive as ~3H-Tdr. LCT.

本文报道应用植物血凝素(PHA)为刺激原的氚化胸腺嘧啶核苷掺入淋巴细胞转化试验(~3H-TdR·LCT)检测90例各型肝炎、13例无症状HBsAg携带者,以及41名正常人的细胞免疫状况,并与形态学淋巴细胞转化试验(LCT)、玫瑰花环形成试验(E·RFC)相比较.结果提示,细胞免疫状态与病情预后关系密切.机体受肝炎病毒感染后,细胞免疫受明显抑制,若能迅速恢复,则病程终止;若抑制非常严重,终将促使患者死亡;若受持续抑制或原来机体细胞免疫功能较差,长期未能恢复正常者,则导致慢性化.在各型肝炎及携带者中,LCT均值无明显差异;E·RFC的结果虽与~3H—TdR·LCT相近,但灵敏性不及后者.本文并讨论了细胞免疫增强剂的可能适应证。

 
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