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    Study on the Clinical Risk Factors, Polymorphism of Lipoprotein Lipase Gene and Its Post-heparin Plasma Activity Among Patients with Premature Coronary Heart Disease
    早发冠心病患者临床危险因素、脂蛋白脂酶P,H基因多态性及其酶活性研究
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    The Expression of Adhesion Molecules in Serum of Patients with CHD and Intervention Study with AT_1 Receptor Antagonists
    粘附分子在冠心病患者血清中的表达及AT_1受体拮抗剂的干预研究
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    The Study on Vulnerable Blood in the Elderly Male Patients with CAD and Effect of Hcy on the Expression of TM and TFPI in ECV304 Cells
    老年男性冠心病患者脆性血液的临床研究及Hcy对内皮细胞表达TM和TFPI的影响
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    The Study of Angiographic Evaluation on Tissue Level Perfusion in Patients with Non-ST-eleva-tion Acute Coronary Syndrome
    非ST段抬高型急性冠脉综合征患者组织微灌注的冠脉造影评价研究
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    Clinical Trials of AngⅡ Blockers in Treating Patients with Both Type 2 Diabetes Mellitus and Atherosclerosis, and the Relationship between ACE (I/D), AT_1R (A1166C) Gene Polymorphism and Early Effectiveness of ACEI
    T2DM合并AS患者ACE(I/D)、AT_1R(A1166C)基因多态性与ACEI近期疗效相关性的研究
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    Study on Structural Remodeling and Ca~(2+)-CaMKⅡ-CREB Signaling Pathway in Atrial Myocardium of Pathway in Atrial Myocardium of Patients with Chronic Atrial Fibrillation
    慢性房颤病人心房肌组织重构及Ca~(2+)-CaMKⅡ-CREB信号通路的研究
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    Study of Serum Iron Level Change in Patients with Acute Myocardial Infarction
    急性心肌梗塞病人血清铁浓度变化的研究
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    THE EFFECTIVENESS OF THE DRUG "522" IN THE PREVENTION OF LEUCOPENIA IN CANCER PATIENTS RECEIVING HALF BODY IRRADIATION
    “522”对半身照射肿瘤病人白细胞的防护效果
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    THE RELATIONSHIP BETWEEN SERUM T_3, T_4 AND PRA, AII, PAC IN PATIENTS WITH HYPERTHYROIDISM
    甲亢病人T_3、T_4值与肾素、血管紧张素Ⅱ和醛固酮水平的关系
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    Epinephrine Induced Platlet Aggregation Function in Patients with Congestive Heart Failure after Alpha_2-receptor Blockade
    α_2受体阻滞后肾上腺素诱导的心衰病人血小板的聚集功能测定
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    A Clinical Study of Reversed Effect on the Formation of Ventricular Aneurysm by PCI and the Level Change of Myocardial Necrotic Inflammatory Markers in Patients with Acute Myocardial Infarction
    PCI对急性心肌梗死室壁瘤的逆转效应及其心肌坏死炎症标记物水平变化的临床研究
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    Mutations Profile in Chinese Patients with Hypertrophic Cardiomyopathy and Correlation between Genotype and Phenotype
    中国肥厚型心肌病的致病基因突变的筛查、基因型与表现型的关系、背景基因对表现型的影响研究
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    Study of Influence of Collagen Network Remodeling on Left Ventricular Hypertrophy and Diastolic Function in the Patients with Essential Hypertension
    高血压左室重构和舒张功能异常的临床研究
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    Clinical Study on Heart Rate Variability in Patients with Coronary Artery Disease
    心率变异性的临床研究
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    CTLA-4Ig or Anti-CD40LmAb (4F1) Regulate T Cell Anergy and Hematopoiesis Recovery of Aplastic Anemia Patients in Vitro
    CTLA-4Ig或抗CD40L单抗体外诱导再生障碍性贫血T细胞免疫无能和促进造血恢复的研究
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  patients
Genomic DNA was extracted from blood samples of healthy controls and from patients with HBV infection.
      
The immunoassay was used to check the BALP of the blood serum that was from 42 primary osteosarcoma patients.
      
The patients were followed up from five months to 49 months with an average of 24.3 months.
      
Detection of abnormal myocardial perfusion is crucial to the prognosis of patients with coronary artery disease (CAD) after they have undergone percutaneous coronary intervention (PCI).
      
For those patients with acute or total occlusion, the levels of myocardial perfusion before and after PCI were similar, as determined by IC-MCE and visually analyzed from 61 segments (P >amp;lt; 0.05).
      
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The clinical features of 415 attacks of rheumatic fever observed in 365 adult patients are described, and some of the diagnostic problems are discussed, 102 of the attacks were considered to be initial and 313 recurrent attacks. Pre-existing chronic valvular disease was diagnosed in 184 cases. The attack rate of rheumatic fever by season was found to be highest in late Winter and Spring, with the peak incidence in the months of March and April. A history of preceding sore throat was elicited in 41% of...

The clinical features of 415 attacks of rheumatic fever observed in 365 adult patients are described, and some of the diagnostic problems are discussed, 102 of the attacks were considered to be initial and 313 recurrent attacks. Pre-existing chronic valvular disease was diagnosed in 184 cases. The attack rate of rheumatic fever by season was found to be highest in late Winter and Spring, with the peak incidence in the months of March and April. A history of preceding sore throat was elicited in 41% of the rheumatic attacks, and inflammatory signs in the pharynx and tonsils were observed in 58.6% of the attacks. The antistreptolysin O titer was above 250 units in 80% of the cases examined. Among the clinical manifestations arthritis and carditis were most common, occurring in 55.7% and 49.9% respectively, while arthralgia without frank inflammatory signs was noted in 30% of the attacks. The incidence of arthritis was lower in the cases with chronic valvular defects than in cases without. In 29% of the cases ECG abnormalities constituted the sole clinical evidence of carditis. Since prolongation of P-R interval or higher grades of atrioventricular block are relatively common in rheumatic fever and other manifestations of rheumatic carditis like murmurs, cardiac enlargement, pericarditis and heart failure are equally non-speclfic, it is suggested that a-v block be included as evidence of carditis rather than considered as a minor manifestation if one adopts Jones' criteria for the diagnosis of rheumatic fever. In the presence of chronic valvular disease frank arthritis was uncommon and signs of carditis were often masked by those of valvular defects so that in 38.5% of cases the diagnosis of rheumatic activity had to depend upon a combination of clinical and laboratory signs generally concidered as minor rheumatic manifestations according to Jones' criteria.

1.本文报告成人急性风湿热366例,經住院观察的急性发作共415次,其中102次診断为初发,313次为复发。发作見于已有慢性心瓣缺损者計184例(218次发作),无心瓣缺损証据者182例(197次发作)。对发病季节、与溶血性鏈球菌感染的关系、临床表現、实验室发見、病程及病死率等作了分析。重点討論了本病的診断问題。 2.风湿热在春冬二季的发病率較高,41%的风湿发作前有咽痛,58.6%的风湿发作时咽部尚有炎症表現,仅24.7%的风湿发作前后均无咽炎的証据。約有80%发作中抗鏈球菌溶血素“O”滴定度在250单位以上。以上数字有力地說明了风湿热和鏈球菌感染之间的密切关系。 3.临床表現中以关节炎最为常見,发生率为55.7%,仅有关节酸痛的有30%。已有慢性心瓣缺损的病例中仅37.6%有关节炎,其发生率远低于无慢性心瓣缺损的病例(75.6%)。 4.心炎見于49.9%的发作中,其临床表現有时颇不明显。仅在心电图檢查中发見者有41例,占所有經过心电图檢查的心炎病例的29%。由此可見心电图检查对診断心炎的独特价值。 5.在曾作心电图檢查的250次发作中有82次(32.8%)发見房窒傳导阻滞,其中68次为P-R间期延长。作...

1.本文报告成人急性风湿热366例,經住院观察的急性发作共415次,其中102次診断为初发,313次为复发。发作見于已有慢性心瓣缺损者計184例(218次发作),无心瓣缺损証据者182例(197次发作)。对发病季节、与溶血性鏈球菌感染的关系、临床表現、实验室发見、病程及病死率等作了分析。重点討論了本病的診断问題。 2.风湿热在春冬二季的发病率較高,41%的风湿发作前有咽痛,58.6%的风湿发作时咽部尚有炎症表現,仅24.7%的风湿发作前后均无咽炎的証据。約有80%发作中抗鏈球菌溶血素“O”滴定度在250单位以上。以上数字有力地說明了风湿热和鏈球菌感染之间的密切关系。 3.临床表現中以关节炎最为常見,发生率为55.7%,仅有关节酸痛的有30%。已有慢性心瓣缺损的病例中仅37.6%有关节炎,其发生率远低于无慢性心瓣缺损的病例(75.6%)。 4.心炎見于49.9%的发作中,其临床表現有时颇不明显。仅在心电图檢查中发見者有41例,占所有經过心电图檢查的心炎病例的29%。由此可見心电图检查对診断心炎的独特价值。 5.在曾作心电图檢查的250次发作中有82次(32.8%)发見房窒傳导阻滞,其中68次为P-R间期延长。作者等认为,P-R间期延长或更高度的房室傳导阻滞,若发見于有鏈球菌感染之后的年青患者,应作为急性风湿性心炎的診断依据之一。 6.在已有慢性心瓣病的病例中,有38.5%得根据Jones氏診断标准中的几項次要表現而診断为风湿活动。 7.366例中58.5%有风湿热的复发,其中半数发生子初发以后的第一年內。住院期的当时病死率为6.5%。

Intracardiac phonocardiography was studied both in human beings and animals.The local- made microphone sealed in the tip of a Courn- and's cardiac catheter was used.The phonocar- diogram was recorded through N.E.P.mul- tichannel physiological recorder. Ten noncardiac patients were subjected to the study.To each of them a No.7 phonoca- theter was inserted through the peripheral vein to the right heart.Heart sounds were recorded in the pulmonary artery,the right ventricle and the right auricle.Ordinary phonocardiogram,...

Intracardiac phonocardiography was studied both in human beings and animals.The local- made microphone sealed in the tip of a Courn- and's cardiac catheter was used.The phonocar- diogram was recorded through N.E.P.mul- tichannel physiological recorder. Ten noncardiac patients were subjected to the study.To each of them a No.7 phonoca- theter was inserted through the peripheral vein to the right heart.Heart sounds were recorded in the pulmonary artery,the right ventricle and the right auricle.Ordinary phonocardiogram, limb leads electrocardiogram and carotid pulse tracing were recorded simultaneously.In the animal study,ten dogs were used.Under ex- perimental condition,eight dogs had their hearts exposed through open-chest,No.4 or No.7 phonocatheter was inserted in each heart cham- ber,the ascending aorta and the pulmonary artery either by direct puncture or through in- cision.Additional tracings were recorded when aortic stenosis and pulmonary stenosis had been artificially created.In the remaining two dogs, the phonocatheter being inserted through jugular vein,tracings from right heart were recorded only. All the intracardiac phonocardiographic tracings were carefully analyzed and compared with those ordinary phonocardiograms.The results are presented in detail. The authors believe that:(1) intracardiac phonocardiogram which has been obtained in each heart chamber or great vessel reflects the heart sound produced there;(2) the 2nd com- ponent of the 1st heart sound is likely produced by closure of the atrioventricular valves,while the 3rd component is produced by opening of the semilunar valves;(3) there is always a systolic murmur in the pulmonary artery;(4)cardiac murmur is transmitted in the direction of blood flow,and is not transmitted in the opposite direction of blood flow;(5)when intracardiac phonocardiogram is recorded care is taken not to include the sound produced by friction bet- ween microphone and endocardial surface of the heart.

本文报告应用国产微型心音图微音器,通过心脏插管检查,进行人及狗心腔内心音图检查的结果。认为此微音器可以记录人的一侧心脏腔内的心音,对杂音的起源有定位作用,是诊断心脏病中的一项有价值的工具。文中对10例正常人右心各腔与10只狗左右心各腔的心音图进行分析,并就正常人右心各腔心昔图的特点、第一音的第二、三部分的发生机制、心腔内杂音的传播情况以及本检查应注意的事项等方面,加以讨论。

In this paper, a preliminary assessment of hyperlipoproteinemia classification is presented. Hyperlipoproteinemia patients were screened by noting the appearance of the serum left overnight at 4℃ and measuring serum oholesterol and triglyceride concentrations. The lipoprotein was determined concurrently by a paper electrophoretic procedure involving prestaining.

本文目的在于通过血清外观(包括乳糜微粒试验)、血脂水平和脂蛋白分型电泳图谱的综合分析,对我国人高脂蛋白血症分型提出初步认识。一、33例正常人血清外观,有3例轻度混浊,乳糜微粒试验全部阴性。二、43例男性和28例女性的胆固醇相应为166.6±23.5和176,4±29毫克/100毫升;34例男性和28例女性的甘油三酯分别为107.42±41和104.4±29毫克/100毫升,两者在性别上均无统计学显著差异。三、采用累加频数分布曲线计算出胆固醇、甘油三酯和各个脂蛋白的正常高限:胆固醇为198毫克/100毫升,甘油三酯137毫克/100毫升,α-脂蛋白240毫克/100毫升(44.5%),β-脂蛋白309毫克/100毫升(57%),前β-脂蛋白124毫克/100毫升(22.5%)。四、通过测定胆固醇、甘油三酯浓度及血清外观可将高脂血症按高脂蛋白血症分型。在所测33名正常人中血清胆固醇的升高与β-脂蛋白的相符率达85.4%,甘油三酯与前β-脂蛋白的相符率亦达2/3以上。五、鉴于血清外观、血脂浓度通常与一定脂蛋白的浓度有关,因此可用血清外观及血脂测定来筛选高脂蛋白血症及初步预测其类型;相反,依据脂蛋白电泳图谱,不仅可对...

本文目的在于通过血清外观(包括乳糜微粒试验)、血脂水平和脂蛋白分型电泳图谱的综合分析,对我国人高脂蛋白血症分型提出初步认识。一、33例正常人血清外观,有3例轻度混浊,乳糜微粒试验全部阴性。二、43例男性和28例女性的胆固醇相应为166.6±23.5和176,4±29毫克/100毫升;34例男性和28例女性的甘油三酯分别为107.42±41和104.4±29毫克/100毫升,两者在性别上均无统计学显著差异。三、采用累加频数分布曲线计算出胆固醇、甘油三酯和各个脂蛋白的正常高限:胆固醇为198毫克/100毫升,甘油三酯137毫克/100毫升,α-脂蛋白240毫克/100毫升(44.5%),β-脂蛋白309毫克/100毫升(57%),前β-脂蛋白124毫克/100毫升(22.5%)。四、通过测定胆固醇、甘油三酯浓度及血清外观可将高脂血症按高脂蛋白血症分型。在所测33名正常人中血清胆固醇的升高与β-脂蛋白的相符率达85.4%,甘油三酯与前β-脂蛋白的相符率亦达2/3以上。五、鉴于血清外观、血脂浓度通常与一定脂蛋白的浓度有关,因此可用血清外观及血脂测定来筛选高脂蛋白血症及初步预测其类型;相反,依据脂蛋白电泳图谱,不仅可对高脂蛋白血症的类型作出初步判断,也可对血脂水平作出大致估计,两者互相补充,彼此对照,再结合临床资料,无疑会增强辨别高脂蛋白血症类型的可靠性。最后,按照我们的初步认识,对四个高脂蛋白血症的病例作了分型的尝试。

 
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