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entered the analysis of results
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  进入结果分析
    RESULTS All the 16 patients with frontal lobe damage and 20 normal controls entered the analysis of results.
    结果:16例额叶损伤患者和20例正常人均进入结果分析
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    RESULTS: According to intention-to-treat analysis, all the 20 patietns entered the analysis of results.
    结果:按意向处理分析,实验纳入患者20例,全部进入结果分析
短句来源
    RESULTS According to intention-to-treat analysis24 patients all entered the analysis of results.
    结果:按意向处理分析,24例患者全部进入结果分析
短句来源
    . RESULTS: According to intention-to-treat analysis, 171 patients withtraumatic thoracolumbar fracture were involved, all of them finished the 1-year follow-up and entered the analysis of results.
    结果:按意向处理分析,实验纳入外伤性胸腰段脊柱骨折患者117例,全部完成1年随访而进入结果分析
短句来源
    RESULTS: All the 34 patients finished the test and entered the analysis of results.
    结果:34例患者均完成量表测试,全部进入结果分析
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AIM: To observe the changes of periopeative hemodynamics and various myocardial enzymes during orthotopic liver transplantation (OLT), and investigate the association between hemodynamics and myocardial damage.METHODS: Twenty patients with end disease of hepatism, whowere selected from the Third Affiliated Hospital of Sun Yat-sen University between June and September 2004, were scheduled for OLT under combined general anesthesia. The hepatic duct, left and right hepatic arteries and portal veins were ligated...

AIM: To observe the changes of periopeative hemodynamics and various myocardial enzymes during orthotopic liver transplantation (OLT), and investigate the association between hemodynamics and myocardial damage.METHODS: Twenty patients with end disease of hepatism, whowere selected from the Third Affiliated Hospital of Sun Yat-sen University between June and September 2004, were scheduled for OLT under combined general anesthesia. The hepatic duct, left and right hepatic arteries and portal veins were ligated routinely, the superior and inferior vena cavas were clipped to close from front to behind with the interruption claw of vena cava, supplied liver anastomosis was conducted after diseased liver was cut. The cava was anastomosed firstly, and the stoma was shaped as inverted triangle, and then portal veins were anastomosed, the liver blood supply was recovered to enter the new liver period, and then hepatic arteries and bile duct were anastomosed in order. Blood samples were drawn from central vein at preoperative stage, 30 minutes after anhepatic stage, 30 minutes after reperfusion stage, the end of surgery and 24 hour after operation respectively, the myocardial zymogram was determined, meanwhile, perioperative heart rate, cardiac output, central venous pressure and mean arterial blood pressure were measured. RESULTS: According to intention-to-treat analysis, all the 20 patietns entered the analysis of results. ① Postoperative recovery: All patients received orthotopic liver transplantation successfully. The duration of operation was (335.74±74.04) minutes, and the time of anhepatic phase was (36.37±7.90) minutes. 3 Patients suffered from heart failure among whom 2 died after OLT, the others all recovered very well. ② Changes of hemodynamics: The cardiac output and central venous pressure were decreased at the anhepatic stage (P < 0.01) and increased at the reperfusion stage (P < 0.01 or P < 0.05). The mean arterial blood pressure once decreased while blocking and opening the inferior vena cave, but it could keep stable after applying some vasoactive drugs. Heart rate increased while entering the anhepatic stage, when it came into the reperfusion stage, heart rate increased in the early period and rebounded to the preoperative level. ③Changes of myocardial zymogram: Compared with the preoperative stage: Only myohaemoglobin was significantly increased (P < 0.01) at 30 minutes after anhepatic stage, and others had no significant differences (P > 0.05) At 30 minutes after reperfusion and the end of the surgery, all of the values of myocardial zymogram were significant increased And at the phase of 24 hour after operation, all the values increased significantly (P < 0.05 or 0.01) except that lactate dehydrogenase isoenzyme had no obvious changes (P > 0.05). Compared with the stage of 30 minutes after reperfusion, aspartate aminotransferase, lactate dehydrogenase, lactate dehydrogenase isoenzyme and alpha-hydroxybutyrate dehydrogenase at 24 hour after operation were significantly decreased (P < 0.05), and creatine kinase was significantly increased (P < 0.05), and isoenzyme of creatine kinase and myohaemoglobin had no significant differences (P > 0.05). CONCLUSION: After reperfusion high hemodynamics occurred and myocardial zymogram increased generally, and myocardial zymogram recovered at 24 hours after OLT, which indicated that there is divergence phenomenon between hemodynamics and myocardial zymogram.

目的:观察肝移植围术期血流动力学以及各种心肌酶的变化,探讨血流动力学变化与心肌损害的关系。方法:选取2004-06/09中山大学第三附属医院拟行原位肝移植术的终末期肝病患者20例,静吸复合全身麻醉下接受原位肝移植术。常规结扎切断肝管、肝左右动脉和门静脉,用肝上下腔静脉阻断钳从前至后夹闭肝上下腔静脉,切除病肝后进行供肝吻合。先吻合腔静脉,腔静脉吻合口为倒三角形,再吻合门静脉,恢复供肝血流,进入新肝期,再依次吻合肝动脉和胆管。分别在术前、无肝前、无肝期30min、新肝期30m in、术毕、术后24h各采中心静脉血3m L,测定心肌酶谱。同时测量围术期心率、心输出量、中心静脉压、平均动脉压。结果:按意向处理分析,实验纳入患者20例,全部进入结果分析。①全部患者术后转归情况:20例患者均成功接受原位肝移植术。手术时间(335.74±74.04)min,无肝期时间(36.37±7.90)m in。术后3例出现心脏衰竭,心脏衰竭患者中有2例最终死亡。其余患者术后均恢复良好。②全部患者肝移植围术期血流动力学的变化:心输出量和中心静脉压在无肝期下降(P<0.01),进入新肝期增高(P<0.01或0.05);平均动脉压在阻断和...

目的:观察肝移植围术期血流动力学以及各种心肌酶的变化,探讨血流动力学变化与心肌损害的关系。方法:选取2004-06/09中山大学第三附属医院拟行原位肝移植术的终末期肝病患者20例,静吸复合全身麻醉下接受原位肝移植术。常规结扎切断肝管、肝左右动脉和门静脉,用肝上下腔静脉阻断钳从前至后夹闭肝上下腔静脉,切除病肝后进行供肝吻合。先吻合腔静脉,腔静脉吻合口为倒三角形,再吻合门静脉,恢复供肝血流,进入新肝期,再依次吻合肝动脉和胆管。分别在术前、无肝前、无肝期30min、新肝期30m in、术毕、术后24h各采中心静脉血3m L,测定心肌酶谱。同时测量围术期心率、心输出量、中心静脉压、平均动脉压。结果:按意向处理分析,实验纳入患者20例,全部进入结果分析。①全部患者术后转归情况:20例患者均成功接受原位肝移植术。手术时间(335.74±74.04)min,无肝期时间(36.37±7.90)m in。术后3例出现心脏衰竭,心脏衰竭患者中有2例最终死亡。其余患者术后均恢复良好。②全部患者肝移植围术期血流动力学的变化:心输出量和中心静脉压在无肝期下降(P<0.01),进入新肝期增高(P<0.01或0.05);平均动脉压在阻断和开放下腔静脉后3min内有一过性下降,应用血管活性药后基本维持稳定;心率在无肝期增快,进入新肝期早期增高,以后逐渐恢复到术前水平。③全部患者肝移植围术期心肌酶谱的变化:与麻醉后术前比较:无肝期30min除肌红蛋白显著增高外(P<0.01),其余各种酶均基本相似(P>0.05);新肝期30m in、术毕的心肌酶谱各值均显著增高(P<0.05或0.01);术后24h除乳酸脱氢酶同工酶无明显变化外(P>0.05),其余各种酶均显著增高(P<0.05或0.01)。与新肝30m in比较:术后24h的谷草转氨酶、乳酸脱氢酶、乳酸脱氢酶同工酶、α-羟丁酸脱氢酶均显著降低(P<0.05),肌酸激酶则显著增高(P<0.05),肌酸激酶同工酶和肌红蛋白基本无变化(P>0.05)。结论:新肝期表现为高血流动力学,而心肌酶普遍增高,术后24h开始恢复,提示开放后血流动力学与心肌损害存在分离现象。

AIM To compare the differences of motor function and disease progress between patients with Parkinson disease treated with surgery plus medicine and those treated with medicine only after 1 year. METHODS Twenty-four patients with primary Parkinson disease were selected from the Department of Neurosurgery Tangdu Hospital of the Fourth Military Medical University of Chinese PLA between March 2003 and March 2005.They were all refractory to drug therapyand clinically evaluated to receive surgery for globus pallidus...

AIM To compare the differences of motor function and disease progress between patients with Parkinson disease treated with surgery plus medicine and those treated with medicine only after 1 year. METHODS Twenty-four patients with primary Parkinson disease were selected from the Department of Neurosurgery Tangdu Hospital of the Fourth Military Medical University of Chinese PLA between March 2003 and March 2005.They were all refractory to drug therapyand clinically evaluated to receive surgery for globus pallidus impairment.Twelve cases received unilateral surgery for globus pallidus impairment and had follow-up data after 1 year were taken as the surgery group still received drug therapy after 1 yearanother 12 cases could not accept surgery for different reasons and only received drug therapy as the non-surgery group.The disease condition and progress were assessed with the unified Parkinson disease rating scale motor score UPDRSin the surgery group at the first diagnosis and at 1 week and 1 year after surgery and in the non-surgery group at the first diagnosis and at 1 year after surgery respectively. RESULTS According to intention-to-treat analysis24 patients all entered the analysis of results.The score of UPDRS at the first diagnosis had no significant difference between the surgery group and non-surgery group 30.41±5.6529.30±5.50P > 0.05it was significantly decreased in the surgery group at 1 week after surgery20.17±2.31it was significantly lower I the surgery group than in the non-surgery group at 1 year after surgery 25.66±3.1536.12±5.22P=0.000. The score had no difference in the surgery group at 1 week and 1 month after surgery also in the non-surgery before and after 1 year t= -0.352P=0.726. CONCLUSION The follow-up observation proves that the ameliorated degree of motor function in the patients accepted surgery for globus pallidus impairment is obviously superior to that in those did not accepted but there is no difference in the velocity of postoperative disease process between the patients accepted the surger or not. So when the effect of drug therapy is no so good surgery can obviously ameliorate the symptoms and improve their quality of life.

目的:比较手术加药物治疗的帕金森病患者和单纯药物治疗的患者1年后运动功能以及病情进展速度的差异。方法:选择2003-03/2005-03解放军第四军医大学唐都医院神经外科收治的原发性帕金森病患者24例,均为药物难治性,经临床评估可以接受苍白球毁损术者。其中12例接受单侧苍白球毁损术治疗并且有1年后随访资料者为手术组(术后1年仍接受药物治疗),另12例因各种原因不能接受手术仅进行单纯药物治疗者为非手术组。手术组首诊、术后1周及1年后,非手术组首诊及1年后均进行统一帕金森病评定量表运动部分评分(总分108分,评分越高,运动功能越差)评估病情和进展。结果:按意向处理分析,24例患者全部进入结果分析。首诊时手术组和非手术组患者统一帕金森病评定量表运动部分评分比较无差异(30.41±5.65,29.30±5.50,P>0.05),术后1周手术组评分显著下降(20.17±2.31);1年后手术组评分显著低于于非手术组(25.66±3.15,36.12±5.22,P=0.000);而手术组术后1周与术后1年的评分差值与非手术组1年前后的评分差值比较无差异(t=-0.352,P=0.726)。结论:随访观察证明,接受了苍白球...

目的:比较手术加药物治疗的帕金森病患者和单纯药物治疗的患者1年后运动功能以及病情进展速度的差异。方法:选择2003-03/2005-03解放军第四军医大学唐都医院神经外科收治的原发性帕金森病患者24例,均为药物难治性,经临床评估可以接受苍白球毁损术者。其中12例接受单侧苍白球毁损术治疗并且有1年后随访资料者为手术组(术后1年仍接受药物治疗),另12例因各种原因不能接受手术仅进行单纯药物治疗者为非手术组。手术组首诊、术后1周及1年后,非手术组首诊及1年后均进行统一帕金森病评定量表运动部分评分(总分108分,评分越高,运动功能越差)评估病情和进展。结果:按意向处理分析,24例患者全部进入结果分析。首诊时手术组和非手术组患者统一帕金森病评定量表运动部分评分比较无差异(30.41±5.65,29.30±5.50,P>0.05),术后1周手术组评分显著下降(20.17±2.31);1年后手术组评分显著低于于非手术组(25.66±3.15,36.12±5.22,P=0.000);而手术组术后1周与术后1年的评分差值与非手术组1年前后的评分差值比较无差异(t=-0.352,P=0.726)。结论:随访观察证明,接受了苍白球毁损术的患者运动功能改善程度明显优于未接受手术的患者;但是手术组患者术后的病情进展速度与非手术组患者无差别。因此,当患者药物治疗效果欠佳时,选择手术治疗可明显改善症状,提高生活质量。

AIM: To observe the effect on the recovery of the height of damagedvertebrae and correction of angulated deformity by AF pedicle of vertebralarch nail system reduce fixation and implant fusion in thoracolumbarfracture and dislocation.METHODS: Totally 117 patients with traumatic thoracolumbar fracturewere selected from the Department of Orthopaedics, Luocun People'sHospital of Nanhai City, the Department of Surgery, Baiyun District TaiheTown Hospital of Guangzou City and the Department of Orthopaedics,Zhujiang...

AIM: To observe the effect on the recovery of the height of damagedvertebrae and correction of angulated deformity by AF pedicle of vertebralarch nail system reduce fixation and implant fusion in thoracolumbarfracture and dislocation.METHODS: Totally 117 patients with traumatic thoracolumbar fracturewere selected from the Department of Orthopaedics, Luocun People'sHospital of Nanhai City, the Department of Surgery, Baiyun District TaiheTown Hospital of Guangzou City and the Department of Orthopaedics,Zhujiang Hospital affiliated to Southern Medical University between July1997 and June 2004. The patients were treated by routine implant of AFpedicle of vertebral arch nail system reduce fixation after anesthesia. Ifthere was no nerve injury, autologous iliac bone or allogeneic bone werefetched directly for posterior fusion of grafted bone. If there were neverinjuries, exploration by fenestration of vertebral lamina was conductedfirstly, and then if the fracture block was reduced, the posterior fusion ofgrafted bone was performed as above_ if the fracture block was not reducedor the reduce was no satisfactory, further decompression was needed. Ifthere was still obvious compression after AF pedicle of vertebral arch nailsystem reduce fixation, secondary annular decompression of fracturedvertebra was conducted by biting out one lateral pedicle of vertebral arch.For those with greater defect after decompression, interbody fusion andintrapyramidal implant were performed at the same time. For those withfracture dislocation, interbody fusion of grafted bone was conducted fromposterior through vertebral canal. The percentage of damaged vertebralheight and change of Cobb angle were measured before and after operationas well as 1 year after operation. .RESULTS: According to intention-to-treat analysis, 171 patients withtraumatic thoracolumbar fracture were involved, all of them finished the 1-year follow-up and entered the analysis of results. As compared with beforeoperation, the percentages of vertebral height were obviously increased[(58.32±7.82), (96.14±9.46), (92.65±10.48)%, P all < 0.01], but the Cobbangles were markedly decreased [(15.58±5.68), (4.26±2.85), (5.47±2.24)°,P all < 0.01] immediately and 1 year after operation in all the patients.CONCLUSION: AF system can effectively recover the height of damagedvertebrae and Cobb angle, and it is a spinal short segmental fixator withsimple manipulation, powerful reduction force, the fine therapeutic efficacycan be achieved by integration with reasonable bone fusion.

目的:观察应用AF椎弓根钉系统复位固定加植骨融合治疗胸腰椎骨折脱位恢复伤椎高度纠正成角畸形的效应。方法:选取1997-07/2004-06南海市罗村人民医院骨科、广州市白云区太和镇医院外科、南方医科大学附属珠江医院骨科收治的外伤性胸腰段椎骨骨折患者117例。患者麻醉后常规植入AF椎弓根钉系统复位固定,如无神经损伤直接取自体髂骨或同种异体骨行后路植骨融合术。若有神经损伤,则先行椎板开窗探查,若骨折块已复位,同上行后路植骨融合。骨折块未复位或复位不理想,则需进一步减压;若经AF椎弓根钉系统复位固定后仍有明显压迫,则需通过咬除一侧椎弓根行骨折脊椎次环状减压术。对减压后缺损较大者,同时行椎间融合加椎体内植骨,对骨折脱位者从后路经椎管行椎间植骨融合术。测量术前、术后及术后1年伤椎椎体高度百分比及Cobb角的变化。结果:按意向处理分析,实验纳入外伤性胸腰段脊柱骨折患者117例,全部完成1年随访而进入结果分析。与术前比较,全部患者的椎高百分比于术后即刻、术后1年均明显提高[(58.32±7.82),(96.14±9.46),(92.65±10.48)%,P均<0.01],Cobb角均明显降低[(15.58±5.68),(4...

目的:观察应用AF椎弓根钉系统复位固定加植骨融合治疗胸腰椎骨折脱位恢复伤椎高度纠正成角畸形的效应。方法:选取1997-07/2004-06南海市罗村人民医院骨科、广州市白云区太和镇医院外科、南方医科大学附属珠江医院骨科收治的外伤性胸腰段椎骨骨折患者117例。患者麻醉后常规植入AF椎弓根钉系统复位固定,如无神经损伤直接取自体髂骨或同种异体骨行后路植骨融合术。若有神经损伤,则先行椎板开窗探查,若骨折块已复位,同上行后路植骨融合。骨折块未复位或复位不理想,则需进一步减压;若经AF椎弓根钉系统复位固定后仍有明显压迫,则需通过咬除一侧椎弓根行骨折脊椎次环状减压术。对减压后缺损较大者,同时行椎间融合加椎体内植骨,对骨折脱位者从后路经椎管行椎间植骨融合术。测量术前、术后及术后1年伤椎椎体高度百分比及Cobb角的变化。结果:按意向处理分析,实验纳入外伤性胸腰段脊柱骨折患者117例,全部完成1年随访而进入结果分析。与术前比较,全部患者的椎高百分比于术后即刻、术后1年均明显提高[(58.32±7.82),(96.14±9.46),(92.65±10.48)%,P均<0.01],Cobb角均明显降低[(15.58±5.68),(4.26±2.85),(5.47±2.24)°,P均<0.01]。结论:AF椎弓根钉系统复位力强,可有效恢复伤椎椎体的高度并纠正成角畸形,提示在良好复位基础上的坚强固定与确实有效的植骨融合是取得理想效果的根本所在。

 
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