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entered into the result analysis
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    ② the linguistic intelligence quotient, operation intelligence quotient and total intelligence quotient of patients in the two groupsRESULTS: Totally 94 patients were involved in the trial, there were 12 cases who dropped down because of not taking in the medicine properly during the trial, so 82 cases entered into the result analysis (42 cases in the yizhi capsule group and 40 in the control group).
    ②两组患者治疗前后言语智商、操作智商、全智商。 结果:参加实验94例,中途由于未按规定服药脱落12例,进入结果分析82例(益智胶囊组42例,对照组40例)。
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    RESULTS: Thirty-six patients in SA group were excluded due to incomplete data,thus there were 30 patients in SA group,62 patients in BA group and 15 controls entered into the result analysis.
    结果:头针组资料不完整患者36例未进入结果分析,最终进入结果分析头针组30例,体针组62例,正常对照组15人。
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    RESULTS: Totally 68 cases entered into the result analysis.
    结果:68例病例全部进入结果分析
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BACKGROUND: There have been researches showing that yizhi capsule can obviously improve the learning memory power of model rats with multi-infarct dementia. What is the effect of the yizhi capsule to multi-infarct dementia?芽 And whether it is effective to improvement of intelligence of patients with multi-infarct dementia. OBJECTIVE: To investigate the effect of yizhi capsule on patients with multi-infarct dementia and its influence to the intelligence, and to compare it with piracetamDESIGN: A randomized controlled...

BACKGROUND: There have been researches showing that yizhi capsule can obviously improve the learning memory power of model rats with multi-infarct dementia. What is the effect of the yizhi capsule to multi-infarct dementia?芽 And whether it is effective to improvement of intelligence of patients with multi-infarct dementia. OBJECTIVE: To investigate the effect of yizhi capsule on patients with multi-infarct dementia and its influence to the intelligence, and to compare it with piracetamDESIGN: A randomized controlled and double blind trial.SETTING: Department of Special Health of the Affiliated Hospital, and Cerebrovascular Disease Institute of Medical College, Qingdao University.PARTICIPANTS: Totally 94 patients, 51 males and 43 females, aged 45-79 years, who were diagnosed to have multi-infarct dementia at Department of Special Health of the Affiliated Hospital of Medical College, Qingdao University from October 1999 to October 2002, were involved in the trial. Informed consent was obtained from the patients. The patients were at random divided as yizhi capsule group (47 cases) and control group (47 cases)METHODS: Medicine for patients in the yizhi capsule group: Yizhi capsule, made from processed flowery knotweed 14 g, ginseng 4 g, acorus 8 g, polygala 6 g , leech 10 g, epimedium 10 g, anemarrhena 6 g, ligasticum 12 g, with each capsule contenting 0.228 g, which was consistent with 10 g raw drug, orally, 6 capsules, 3 time a day. Medicine for patients in the control group: Piracetam 0.9 g, three times a day, orally. The course for both groups was 3 months. The effect was estimated by effect judgment criteria in the guiding principles of clinical research on treatment of dementia with traditional Chinese new drugs issued in 1995 by the Ministry of Health, P.R. China (Markedly effective: The symptoms and signs were obviously improved; the reduction of syndrome integration ≥70%. Improved: The symptoms and signs were all improved, the reduction of syndrome integration ≥30%. Irresponsive: The symptoms and signs were not improved or even deteriorated, the reduction of syndrome integration < 30%). Wechsler Adult Intelligence Scale-Revised in China (WAIS-RC) was used for assay of intelligence, including two parts of linguistic scale and operation scale, altogether 11 tests.MAIN OUTCOME MEASURES: ① The effects for patients of two groups. ② the linguistic intelligence quotient, operation intelligence quotient and total intelligence quotient of patients in the two groupsRESULTS: Totally 94 patients were involved in the trial, there were 12 cases who dropped down because of not taking in the medicine properly during the trial, so 82 cases entered into the result analysis (42 cases in the yizhi capsule group and 40 in the control group). ① Therapeutic result: In the yizhi capsule group 21 cases were markedly effective, 14 cases effective, 7 cases irresponsive, total effective rate was 83 % (35/42); in the control group 7 cases were markedly effective, 15 cases effective, 18 cases irresponsive, total effective rate was 55 % (22/40). The total effective rate in the yizhi capsule group was obviously higher than that in the control group (Z=3.549, P < 0. 001). ② Comparison of data of the linguistic intelligence quotient, operation intelligence quotient and total intelligence quotient of patients in the two groups before and after treatment: Before treatment the data in the yizhi capsule group was basically the same as that in the control group (P > 0.05). After treatment the data in the yizhi capsule group was obviously higher than that in the control group (91.64±24.38, 81.42±19.32; 88.28±20.63, 73.18±18.04; 89.83±22.4, 74.62±20.20, t=5.198 -6.958, P < 0.001).CONCLUSION: Yizhi capsule had a good effect for treatment of multi-infarct dementia, it was better than piracetam in improving the intelligence of the patient with multi-infarct dementia.

背景:已有实验表明益智胶囊可明显改善多发梗死性痴呆模型大鼠学习记忆能力,其对多发梗死性痴呆的疗效如何?对多发梗死性痴呆患者智力的改善是否有作用?目的:观察益智胶囊治疗多发梗死性痴呆患者的疗效及对智力的影响,并与吡拉西坦药物进行比较。设计:随机对照、双盲实验。单位:青岛大学医学院附属医院特需保健科,青岛大学医学院脑血管病研究所。对象:选择1999-10/2002-10青岛大学医学院附属医院特需保健科确诊为多发梗死性痴呆患者94例,男51例,女43例;年龄45~79岁。知情同意参加本实验。随机分为益智胶囊组47例和对照组47例。方法:益智胶囊组用药:益智胶囊成分为制何首乌14g,人参4g,石菖蒲8g,远志6g,水蛭10g,淫羊藿10g,知母6g,川芎12g,每粒胶囊含内容物0.228g,相当于生药10g。6粒/次,3次/d,口服。对照组用药:吡拉西坦,0.9g/次,3次/d,口服。两组均治疗3个月。参照卫生部1995年制定发布的中药新药治疗痴呆的临床研究指导原则中的疗效判定标准评估疗效(显效:症状、体征明显改善;证候积分减少≥70%;好转:症状、体征均有好转;证候积分减少≥30%;无效:症状、体征无明显改善,甚或...

背景:已有实验表明益智胶囊可明显改善多发梗死性痴呆模型大鼠学习记忆能力,其对多发梗死性痴呆的疗效如何?对多发梗死性痴呆患者智力的改善是否有作用?目的:观察益智胶囊治疗多发梗死性痴呆患者的疗效及对智力的影响,并与吡拉西坦药物进行比较。设计:随机对照、双盲实验。单位:青岛大学医学院附属医院特需保健科,青岛大学医学院脑血管病研究所。对象:选择1999-10/2002-10青岛大学医学院附属医院特需保健科确诊为多发梗死性痴呆患者94例,男51例,女43例;年龄45~79岁。知情同意参加本实验。随机分为益智胶囊组47例和对照组47例。方法:益智胶囊组用药:益智胶囊成分为制何首乌14g,人参4g,石菖蒲8g,远志6g,水蛭10g,淫羊藿10g,知母6g,川芎12g,每粒胶囊含内容物0.228g,相当于生药10g。6粒/次,3次/d,口服。对照组用药:吡拉西坦,0.9g/次,3次/d,口服。两组均治疗3个月。参照卫生部1995年制定发布的中药新药治疗痴呆的临床研究指导原则中的疗效判定标准评估疗效(显效:症状、体征明显改善;证候积分减少≥70%;好转:症状、体征均有好转;证候积分减少≥30%;无效:症状、体征无明显改善,甚或加重;证候积分减少不足30%)。智力测验使用中国修订的韦氏成人智力量表:包括语言量表和操作量表两部分,共11个分测验。主要观察指标:①两组患者治疗效果。②两组患者治疗前后言语智商、操作智商、全智商。结果:参加实验94例,中途由于未按规定服药脱落12例,进入结果分析82例(益智胶囊组42例,对照组40例)。①治疗效果:益智胶囊组显效21例,有效14例,无效7例,总有效率达83%(35/42);对照组显效7例,有效15例,无效18例,总有效率55%(22/40)。益智胶囊组总有效率明显高于对照组(Z=3.549,P<0.001)。②两组患者治疗前后言语智商、操作智商、全智商数据比较:治疗前益智胶囊组和对照组基本一致(P>0.05)。治疗后益智胶囊组明显高于对照组[91.64±24.38,81.42±19.32;88.28±20.63,73.18±18.04;89.83±22.4,74.62±20.20,(t=5.198~6.958,P<0.001)]。结论:益智胶囊治疗多发梗死性痴呆有良好的疗效,在改善多发梗死性痴呆患者的智力方面优于吡拉西坦。

AIM:To probe into the clinical curative effect of international standardized scheme of scalp acupuncture (SA) on apoplexy,and analyze the influence of SA on hemorheological index,levels of blood lipid and plasma endothelin in patients with apoplexy.METHODS: ①Totally 128 inpatients with apoplexy selected from the Department of Acupuncture and Moxibustion,Wuhan Hospital of Integrated Traditional Chinese and Western Medicine between May 2000 and June 2005 were randomly divided into SA group and body acupuncture...

AIM:To probe into the clinical curative effect of international standardized scheme of scalp acupuncture (SA) on apoplexy,and analyze the influence of SA on hemorheological index,levels of blood lipid and plasma endothelin in patients with apoplexy.METHODS: ①Totally 128 inpatients with apoplexy selected from the Department of Acupuncture and Moxibustion,Wuhan Hospital of Integrated Traditional Chinese and Western Medicine between May 2000 and June 2005 were randomly divided into SA group and body acupuncture (BA) group,with the consents of all the patients knowing the treatment scheme. Meanwhile,15 health examiners who were informed of detection index and consented were taken as control group. ②SA group: Anterior oblique line of vertex-temporal [from Qianshencong to Xuanli (GB 6)] and posterior oblique line of vertex-temporal [from Baihui (DU 20) to Qubin (GB 7)] were selected as the acupoints to perform acupuncture successively for 3 times. At approximately 30°angle,the needle was quickly inserted beneath the scalp. When the needlepoint reached the lower layer of galea aponeurotica and less resistance was felt by fingers,the needle was inserted horizontally as scalp for another 1.0-1.5 inches,then twirled rapidly and continuously at the speed of roughly 220 times per minute. Afterwards the needle was retained for 30 minutes and twirled once every five minutes,and every twirling lasted two or three minutes. During the retention,the affected part should be moved about either actively or passively. BA group: The acupoints were Jianyu (LI 15),Quchi (LI 11),Hegu (LI 14),Waiguan (SJ 5),Huantiao (GB 30),Yanglingquan (GB 34),Zusanli (ST 36) and Sanyinjiao (SP 6),etc,and eight to ten acupoints of them were inserted each time using acupuncture needles (3.3-13.3 inches). Having brought about the needling sensation in acupuncture treatment,uniform reinforcing-reducing method was conducted. The needles were also retained for 30 minutes with hand manipulating of the needles once every five minutes. Both groups received treatments once a day,and a course was comprised of six treatments. There was a one-day interval between two courses,continuously for 4 courses.③The Criteria for Diagnosis and Therapeutic Effect Evaluation of Apoplexy was applied to detect the curative effects of all the patients after 4 courses.④On one day before the treatment and after four courses of treatment,the hemorheological index was assayed with LBY-N6 hemorheological apparatus produced by Tianjin Techcomp Limited; And blood lipid was tested with automatic biochemistry analyzer,while radioimmunoassay (RIA) was utilized to measure the level of plasma endothelin.⑤Difference of ranked data were compared by means of Radit analysis. And u test was used for comparison between groups while t test was used for comparison of enumeration data.RESULTS: Thirty-six patients in SA group were excluded due to incomplete data,thus there were 30 patients in SA group,62 patients in BA group and 15 controls entered into the result analysis.①There was no significant difference in the curative effects between SA group and BA group (u=1.77,P > 0.05).②Compared with before treatment,there was an obvious decrease concerning the whole blood viscosity at high shear rate,plasma high shear rate,hematocrit,erythrocyte aggregation index and whole blood reduction viscosity of patients in SA group (t=2.156-1.783,P < 0.05-0.01); Whereas deformation index increased significantly after treatment (t=2.240,P < 0.05).③In addition,the levels of total cholesterol,triglyceride,low density lipoprotein along with apolipoprotein B were remarkably reduced in SA group after treatment (t=2.473-3.158,P < 0.05-0.01).Meanwhile,the ratio of apolipoprotein A and B was elevated (t=2.154,P < 0.05). ② Before treatment,the level of plasma endothelin was notably higher in SA group than in control group (t=7.345,P < 0.01),but declined dramatically after treatment compared with before treatment in SA group (t=5.943,P < 0.01).CONCLUSION: ①SA treatment has proved to have an affirmative curative effect on apoplexy,identical as BA treatment. ②Moreover,SA can improve hemorheological index,accommodate disturbances in lipid metabolism and reduce level of plasma endothelin.

目的:观察头针国际标准化方案治疗脑卒中的疗效,以及对脑卒中患者血液流变学指标、血脂、血浆内皮素水平的影响。方法:①选择2000-05/2005-06武汉市中西医结合医院针灸科住院的脑卒中患者128例。均对治疗方案知情同意。按编码随机抽取方法分为2组:头针组66例和体针组62例。选择同期本院健康体检者15人为正常对照组,均对检测指标知情同意。②头针组:取健侧顶颞前斜线穴前神聪至悬厘雪、顶颞后斜线穴百会至曲鬓雪,从顶颞前斜线、顶颞后斜线从上至下连刺3针,针尖与头皮呈30°左右夹角,快速刺入头皮下,当针尖抵达帽状腱膜下层、指下感到阻力减少时使针与头皮平行,刺入1.0~1.5寸,然后快速连续捻转,捻针速度保持在220次/min左右,留针30min,留针期间每隔5min捻针1次,每次两三分钟,留针期间需配合主动或被动活动患肢。体针组:选穴肩、曲池、合谷、外关、环跳、阳陵泉、足三里、三阴交等,每次8~10个穴位,用3.3~13.3寸毫针刺入,得气后施以平补平泻手法,留针30min,每隔5min行针1次。2组治疗均1次/d,6次1个疗程,疗程间隔1d,连续治疗4个疗程。③参考《中风病诊断与疗效评定标准》评定标准判定2组治疗...

目的:观察头针国际标准化方案治疗脑卒中的疗效,以及对脑卒中患者血液流变学指标、血脂、血浆内皮素水平的影响。方法:①选择2000-05/2005-06武汉市中西医结合医院针灸科住院的脑卒中患者128例。均对治疗方案知情同意。按编码随机抽取方法分为2组:头针组66例和体针组62例。选择同期本院健康体检者15人为正常对照组,均对检测指标知情同意。②头针组:取健侧顶颞前斜线穴前神聪至悬厘雪、顶颞后斜线穴百会至曲鬓雪,从顶颞前斜线、顶颞后斜线从上至下连刺3针,针尖与头皮呈30°左右夹角,快速刺入头皮下,当针尖抵达帽状腱膜下层、指下感到阻力减少时使针与头皮平行,刺入1.0~1.5寸,然后快速连续捻转,捻针速度保持在220次/min左右,留针30min,留针期间每隔5min捻针1次,每次两三分钟,留针期间需配合主动或被动活动患肢。体针组:选穴肩、曲池、合谷、外关、环跳、阳陵泉、足三里、三阴交等,每次8~10个穴位,用3.3~13.3寸毫针刺入,得气后施以平补平泻手法,留针30min,每隔5min行针1次。2组治疗均1次/d,6次1个疗程,疗程间隔1d,连续治疗4个疗程。③参考《中风病诊断与疗效评定标准》评定标准判定2组治疗4个疗程后疗效。④于治疗前1d和治疗4个疗程后采用中国天津天美公司生产的LBY-N6型血液流变仪检测血液流变学指标;采用全自动生化分析仪检测血脂水平;用放射免疫法测定血浆内皮素水平。⑤等级资料差异比较采用Ridit分析,组间比较u检验;计量资料差异比较采用t检验。结果:头针组资料不完整患者36例未进入结果分析,最终进入结果分析头针组30例,体针组62例,正常对照组15人。①头针组与体针组疗效差异不明显(u=1.77,P>0.05)。②头针组治疗后,全血黏度高切变率、血浆高切变率、红细胞压积、红细胞聚集指数、全血还原黏度较治疗前明显降低(t=2.156~1.783,P<0.05~0.01);红细胞变形指数较治疗前明显升高穴t=2.240,P<0.05雪。③头针治疗后,血总胆固醇、三酰甘油、低密度脂蛋白胆固醇、载脂蛋白B水平较治疗前明显降低(t=2.473~3.158,P<0.05~0.01),载脂蛋白A/B较治疗前明显升高(t=2.154,P<0.05)。④头针组治疗前血浆中内皮素水平明显高于正常对照组穴t=7.345,P<0.01雪鸦头针组治疗后血浆内皮素水平较治疗前明显下降穴t=5.943,P<0.01雪。骨禺结论:①头针治疗脑卒中疗效较好,且与体针治疗效果相当。②头针治疗可改善脑卒中患者血液流变学指标、调节脂类代谢异常、降低血浆内皮素水平。

AIM: To observe the analgesic effect of electroacupuncture (EA) at Jiaji (Extra) in patients with lumbar disc herniation (LDH), and the therapeutic effect on the levels of plasma β-endorphin (β-EP), nitric oxide (NO), superoxide dismutase (SOD) and malondialdehyde (MDA) by EA. METHODS: ①Totally 68 inpatients with LDH selected from the Department of Acupuncture and Moxibustion, Institute of Integrated Traditional Chinese and Western Medicine Affiliated to Tongji Medical College, Huazhong University of Science...

AIM: To observe the analgesic effect of electroacupuncture (EA) at Jiaji (Extra) in patients with lumbar disc herniation (LDH), and the therapeutic effect on the levels of plasma β-endorphin (β-EP), nitric oxide (NO), superoxide dismutase (SOD) and malondialdehyde (MDA) by EA. METHODS: ①Totally 68 inpatients with LDH selected from the Department of Acupuncture and Moxibustion, Institute of Integrated Traditional Chinese and Western Medicine Affiliated to Tongji Medical College, Huazhong University of Science and Technology between May 2003 and May 2006 were randomly divided into treatment group (n=36) and control group (n=32), with their informed consents of the treatment scheme.②The following acupoints were selected: Jiaji (Extra) of double side corresponding to the protrusion and Huantiao (GB 30) on the affected side of protrusion as well as Yanglingquan (GB 34) L4-5 and Weizhong (BL 40) L5-S1 in the treatment group. After deqi sign featured as electric shock conducted to lower limb, HANS acupoint neurostimulator was connected in wave of modulated frequency. The general electric intensity ranged from 10 to 20 mA in current constant which could be accepted by patients. Thirty minutes every day, ten days for a treatment course and at interval of three days. Acupoints such as Shenshu (BL 23), Dachangshu (BL 25), Zhibian (BL 54), Huantiao (GB 30), Chengfu (BL 36), Yinmen (BL 37), Weizhong (BL 40) and Yanglingquan (GB 34) were selected in the control group according to Acupucture and Moxibustion, the stimulation parameter and course were the same as those of treatment group.③The improvement of pain was rated comprehensively using the internationally recognized Multiple Pain Quantity which described and measured pain. The acting time of analgesic effect and the effect-lasting time after the first treatment were observed, and visual analogue scale was adopted to examine and compare the mean pain score before treatment, after the first treatment (instant effect) and before last treatment (long effect). The therapeutic effects were assessed using Yangshi quantitative evaluation scale.④The level of plasma β-EP was measured one day after hospitalization, after the first, one-course and two-course treatments by radioimmunoassay. One day after hospitalization and after the whole treatment, the level of plasma NO was detected with nitrate reductase, plasma SOD with oxyammonia oxidation, and plasma MDA with thiobarbituric acid. RESULTS: Totally 68 cases entered into the result analysis.①There were significant differences in the number of positive words, score of sense and total pain rating index, visual analogue scale and pain intensity between two groups (t=4.52-6.64, P < 0.01).②The time of analgesic effect was shorter, and the effect-lasting time was longer in the treatment group, with significant differences compared with the control group (t=36.63-75.93, P < 0.01).③The score of pain in the treatment group was decreased 48 percent after the first treatment and 88 percent after last treatment. Meanwhile, the score of pain was decreased 30 percent after the first treatment and 69 percent after last treatment in the control group, with statistical significance (t=17.57-67.6, P < 0. 01). And there was dramatic difference between the two groups (t=7.24-7.57, P < 0.01).④The improvement of quantitative evaluation scale was obviously better than the routine intervention for patients with LDH (χ2=5.99, P < 0.05).⑤The levels of plasma β-EP was increased significantly after treatment compared with before treatment (t=2.90-13.86, P < 0.01). Moreover, the increase was more apparent in treatment group and there were significant differences between the two groups (t=124.53-304.40, P < 0.01).⑥The levels of plasma NO and MDA were decreased significantly (t=2.05-8.77, P < 0.05), while the levels of plasma SOD were increased significantly (t=2.39-5.47, P < 0.05) in the two groups after treatment. As compared with the control group, the levels of plasma SOD, NO and MDA were significantly different in the treatment group (t=10.73-22.96, P < 0.01).⑦The therapeutic effects were significant for the youths whereas worse for the elders (χ2=9.88, P < 0.01). CONCLUSION: EA at Jiaji (Extra) can increase the activities of plasma β-EP and SOD, decrease the levels of NO and MDA, display the better instant as well as long-term analgesic effects in patients with LDH, increase the antioxidization capacity and alleviate the damage by oxygen free radicals.

目的:观察电针夹脊穴对腰椎间盘突出症的镇痛时效及其对血浆β-内啡肽、一氧化氮和自由基代谢的影响。方法:①选择2003-05/2006-05华中科技大学同济医学院附属中西医结合医院针灸科腰椎间盘突出症住院患者68例。均对治疗方案知情同意。按编码随机抽取方法分为2组:治疗组36例和对照组32例。②治疗组:选取突出部位相对应的双侧夹脊、患侧环跳,L4~5配患侧阳陵泉,L5~S1配患侧委中。各穴以触电感向下肢传导为得气征象,并接以韩氏穴位神经刺激仪,刺激参数均为调频波、刺激强度(恒流输出)为患者所能接受而不引起痛苦的最大强度,一般为10~20mA。1次/d,每次30min,10d为1疗程,疗程之间间隔3d,共观察2个疗程。对照组:参照《针灸学》选取患侧肾俞、大肠俞、秩边、环跳、承扶、殷门、委中、阳陵泉,刺激参数和疗程同治疗组。③采用国际公认的疼痛询问量表进行疼痛综合评定;观察两组的镇痛起效时间、首次治疗后维持时间,并通过目测类比定级法比较治疗开始前、首次治疗后(代表即刻效应)及最后一次治疗前(代表远期效应)的平均疼痛分数;采用杨氏评分法评定疗效。④于入院第2天、治疗1次后、治疗1疗程后及治疗2疗程后采用放射免疫分析法...

目的:观察电针夹脊穴对腰椎间盘突出症的镇痛时效及其对血浆β-内啡肽、一氧化氮和自由基代谢的影响。方法:①选择2003-05/2006-05华中科技大学同济医学院附属中西医结合医院针灸科腰椎间盘突出症住院患者68例。均对治疗方案知情同意。按编码随机抽取方法分为2组:治疗组36例和对照组32例。②治疗组:选取突出部位相对应的双侧夹脊、患侧环跳,L4~5配患侧阳陵泉,L5~S1配患侧委中。各穴以触电感向下肢传导为得气征象,并接以韩氏穴位神经刺激仪,刺激参数均为调频波、刺激强度(恒流输出)为患者所能接受而不引起痛苦的最大强度,一般为10~20mA。1次/d,每次30min,10d为1疗程,疗程之间间隔3d,共观察2个疗程。对照组:参照《针灸学》选取患侧肾俞、大肠俞、秩边、环跳、承扶、殷门、委中、阳陵泉,刺激参数和疗程同治疗组。③采用国际公认的疼痛询问量表进行疼痛综合评定;观察两组的镇痛起效时间、首次治疗后维持时间,并通过目测类比定级法比较治疗开始前、首次治疗后(代表即刻效应)及最后一次治疗前(代表远期效应)的平均疼痛分数;采用杨氏评分法评定疗效。④于入院第2天、治疗1次后、治疗1疗程后及治疗2疗程后采用放射免疫分析法测定患者血浆β-内啡肽;于入院第2天及疗程结束后用硝酸还原酶法测定血浆中一氧化氮含量,羟胺氧化法测定超氧化物歧化酶活性,硫代巴比妥酸法测定丙二醛含量。结果:68例病例全部进入结果分析。①两组在选词阳性项目数、疼痛分级指数感觉分、疼痛分级指数总分、视觉模拟尺度、疼痛强度上差异均有显著性意义(t=4.52~6.64,P<0.01)。②治疗组的镇痛起效时间短、镇痛维持时间长,与对照组比较差异有显著性意义(t=36.63~75.93,P<0.01)。③治疗组首次治疗后疼痛评分下降48%,治疗结束时共下降88%;同时,对照组首次治疗后的疼痛评分下降30%,治疗结束时下降69%,均有统计学意义(t=17.57~67.6,P<0.01),两组之间差异有显著性意义(t=7.24~7.57,P<0.01)。④治疗组优良率明显优于对照组(χ2=5.99,P<0.05)。⑤治疗后两组β-内啡肽含量均呈明显上升趋势(t=2.90~13.86,P<0.01)。且治疗组上升明显(t=124.53~304.40,P<0.01)。⑥两组治疗后一氧化氮、丙二醛含量均较治疗前显著降低(t=2.05~8.77,P<0.05)、超氧化物歧化酶较治疗前显著增高(t=2.39~5.47,P<0.05)。两组治疗前后一氧化氮、超氧化物歧化酶、丙二醛差值相互比较,差异有显著性意义(t=10.73~22.96,P<0.01)。⑦两种疗法对年轻者疗效显著,对年老者疗效略差(χ2=9.88,P<0.01)。结论:电针夹脊穴可提高腰椎间盘突出症患者血浆β-内啡肽和超氧化物歧化酶活性,具有良好的即时和远期镇痛效应,且维持时间长,并能降低一氧化氮和丙二醛水平,增强机体抗氧化能力,减轻自由基的损害。

 
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