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   时间-效应 在 预防医学与卫生学 分类中 的翻译结果: 查询用时:0.177秒
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时间-效应
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  time-effect
    2. Formaldehyde could cause damage to embryonic development and there were dose-effect relationships and time-effect relationships in vitro.
    2.甲醛能影响体外器官形成期的昆明种小鼠胚胎生长发育,具有一定的胚胎毒性,呈剂量-效应关系和时间-效应关系,以神经管闭合不全、体位翻转不全、脑部形态异常、心脏发育迟缓等畸形为特征;
短句来源
    This showed that PM2.5 could induce the DNA damage in alveolar and aggravate with increase of particle concentration and prolongation of toxicosis time, emerging dearly the dosage-effect and time-effect relations.
    由此可见,PM2.5可引起大鼠肺泡巨噬细胞 DNA 的损伤,且随着 PM2.5浓度的增加及染毒时间的延长而加剧,呈明确的剂量-效应关系和时间-效应关系.
短句来源
    [Objective] To examine the dose/time-effect relationship of cytotoxicity of cadmium to human embryo nephridium cell (293 cell) and observe the effect of co-exposure to cadmium and zinc.
    [目的]分析镉对肾细胞毒作用的剂量-效应关系和时间-效应关系,并观察锌对镉所致损伤的保护作用。 [方法]实验采用人胚肾细胞(293细胞),设对照组、锌组、镉组、镉+锌组。
短句来源
    Conclusion There are dose-effects and time-effect in the damage of spermatogenic functions in mice exposed to manganese.
    结论锰对小鼠生精功能的损伤呈一定的剂量-效应和时间-效应关系。
短句来源
    The exposing dose at level of 1/2 MED,the UDS level of basal cells was inceaseel significantly. For time-effect study,at the levl of 1/8 MED each day,the ch- ange of UDS is not significant.
    对紫外线照射的时间-效应关系研究表明,大于1/2MED的紫外线照射,程序外DNA合成持续增加,而1/8MED组则无明显改变。
短句来源
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  time-response
    ACh and AChE in rat brains significantly changed after 20 min at every dose, showing certain dose-response and time-response relations.
    各剂量组大鼠脑组织ACh及AChE都在暴露20min后就出现显著变化,并显示一定的剂量-效应和时间-效应关系。
短句来源
  time-effect
    2. Formaldehyde could cause damage to embryonic development and there were dose-effect relationships and time-effect relationships in vitro.
    2.甲醛能影响体外器官形成期的昆明种小鼠胚胎生长发育,具有一定的胚胎毒性,呈剂量-效应关系和时间-效应关系,以神经管闭合不全、体位翻转不全、脑部形态异常、心脏发育迟缓等畸形为特征;
短句来源
    This showed that PM2.5 could induce the DNA damage in alveolar and aggravate with increase of particle concentration and prolongation of toxicosis time, emerging dearly the dosage-effect and time-effect relations.
    由此可见,PM2.5可引起大鼠肺泡巨噬细胞 DNA 的损伤,且随着 PM2.5浓度的增加及染毒时间的延长而加剧,呈明确的剂量-效应关系和时间-效应关系.
短句来源
    [Objective] To examine the dose/time-effect relationship of cytotoxicity of cadmium to human embryo nephridium cell (293 cell) and observe the effect of co-exposure to cadmium and zinc.
    [目的]分析镉对肾细胞毒作用的剂量-效应关系和时间-效应关系,并观察锌对镉所致损伤的保护作用。 [方法]实验采用人胚肾细胞(293细胞),设对照组、锌组、镉组、镉+锌组。
短句来源
    Conclusion There are dose-effects and time-effect in the damage of spermatogenic functions in mice exposed to manganese.
    结论锰对小鼠生精功能的损伤呈一定的剂量-效应和时间-效应关系。
短句来源
    The exposing dose at level of 1/2 MED,the UDS level of basal cells was inceaseel significantly. For time-effect study,at the levl of 1/8 MED each day,the ch- ange of UDS is not significant.
    对紫外线照射的时间-效应关系研究表明,大于1/2MED的紫外线照射,程序外DNA合成持续增加,而1/8MED组则无明显改变。
短句来源
更多       
  “时间-效应”译为未确定词的双语例句
    Objective To study on the indexes of 28d and 56d of manganese exposure on spermatogenic function of male mice,and to explore time-effects correlation of manganic toxity.
    目的研究染锰28d与56d小鼠生精功能相关指标的变化,探讨锰生殖毒性的时间-效应关系。
短句来源
    Conclusion It was suggested th at gene expression of MT-1F,MT-1G ,MT-1H and 1X in HPBLs could be used as potential exposure biomarker.
    结论 镉可诱导人外周血淋巴细胞MT-1F、MT -1G、MT- 1H、MT- 1XmRNA表达增加 ,并表现出剂量 -时间 -效应关系 ,可作为潜在的镉接触生物标志物。
短句来源
    [Results] Treatment with different levels of CdCl2(20 μmol/L and 40 μmol/L) for 48 h, significantly reduced the viability and heighten the activity of IDH in 293 cells.
    [结果]实验发现20和40μmol/L镉作用于细胞48h,细胞相对存活率明显降低,细胞上清液中的LDH明显增高,并且在2.5-40μmol/L范围内存在明显的时间-效应、剂量-效应关系。
短句来源
    Conclusion SiO_2 could induce PAI-1 expression of A549 in a time-dependent manner,and AP-1 activation can be observed in early time.
    结论SiO2能够诱导A549细胞PAI1的表达,呈现出明显的时间-效应关系,核转录因子AP1在SiO2刺激的早期被激活。
短句来源
    The Study of the Toxicity of DBP on the Testis in Rats I. Target cell and time-effect relation
    邻苯二甲酸二丁酯对大鼠睾丸毒性的研究 Ⅰ.形态学变化及时间-效应关系
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  time-effect
Time-effect relationship of acupuncture in improving cardiac vegetative nerve function in patients with type II DM
      
By calculating the area under the curve (AUC), of the time-effect curves of the prodrugs, a significantly improved duration of action was found for those prodrugs which have a slow in vitro hydrolysis rate.
      
From time-effect curves the area under the curve for separate time intervals was taken as a measure of dopaminergic activity during that interval.
      
Dose-response and time-effect curves were determined for morphine (1.0-30 mg/kg), levorphanol (0.1 to 3.0 mg/kg), methadone (0.1-3.0 mg/kg), meperidine (1.0-30 mg/kg), oxymorphone (0.03-1.0 mg/kg), and d-amphetamine (0.1-3.0 mg/kg).
      
Dose-response and time-effect curves were also determined for morphine (1.0-30 mg/kg) in rats that had received multiple injections of morphine over a period of 3 days.
      
更多          
  time-response
Aufbauend auf Real-Time-Response-Daten kann die zentrale Bedeutung deutlich gemacht werden, die bereits vor der Debatte vorhandene Einstellungen für die Wahrnehmung der Kandidaten haben.
      
Dieser Beitrag geht der Frage nach, ob Real-Time-Response-Messungen valide und reliable Ergebnisse liefern und damit den Anforderungen der empirischen Sozialforschung genügen.
      
Time-response curves were established and subjected to Arrhenius analysis.
      
In contrast to the time course of these cytokine mRNAs, c-fos and zif268 mRNAs, two early response genes, displayed a greater and earlier time-response profile.
      
In time-response studies, animals were administered 5 mg Hg/kg as HgCl2 and sacrificed after 3, 9, 18, 24, and 48 h.
      
更多          
  time-effect
Time-effect relationship of acupuncture in improving cardiac vegetative nerve function in patients with type II DM
      
By calculating the area under the curve (AUC), of the time-effect curves of the prodrugs, a significantly improved duration of action was found for those prodrugs which have a slow in vitro hydrolysis rate.
      
From time-effect curves the area under the curve for separate time intervals was taken as a measure of dopaminergic activity during that interval.
      
Dose-response and time-effect curves were determined for morphine (1.0-30 mg/kg), levorphanol (0.1 to 3.0 mg/kg), methadone (0.1-3.0 mg/kg), meperidine (1.0-30 mg/kg), oxymorphone (0.03-1.0 mg/kg), and d-amphetamine (0.1-3.0 mg/kg).
      
Dose-response and time-effect curves were also determined for morphine (1.0-30 mg/kg) in rats that had received multiple injections of morphine over a period of 3 days.
      
更多          


TNT was incubated with human erythrocytes and its toxicity was observed. It indicated that TNT induced tl:e simultaneous production of MetHb and O2 with GSH depletion, which demostra ted dramatic relationship of dose-effect and time-effect.

将TNT与离体人红细胞温育观察了TNT对红细胞的毒性。结果表明,TNT可诱发人红细胞高铁血红蛋白和超氧阴离子自由基,两者同时形成,并伴有还原型谷胱甘肽的耗竭。这些影响呈明显的剂量-效应时间-效应关系。

The result of this Study revealed the degeneration of Sertoli cell ultrastructurally, rise of activity of LDH, and reduction of the activity of SDH and ACP. But the testosterone level in serum, and Leidig cell and the tight function of Sertoli cell ultrastfuctrually have no change. So we think the effect of DBP is relative to energy metablism and some function of Sertoli cell, but no relative to the Leidig cell.

作者继DBP对睾丸生精细胞的损伤情况和时间效应关系的研究之后,进一步探讨了DBP对生精细胞毒性作用的机制。结果表明,DBP可损伤支持细胞多种细胞器,使SDH和ACP活性降低,LDH活性增高,但支持细胞紧密连接完整,间质细胞超微结构、睾酮的合成和分泌均无异常。因而认为,DBP对生精细胞的损伤主要是通过影响支持细胞的营养、调控功能而起作用的。

47 workers exposed to chromate for an average of 9 years were investigated.It wasfound that not only the skin,mucous membrane of respiratory tract were damagedshowing abnormal features on X-ray films of chest,but also an apparent increase oflysozyme,β_2-microglobulin and protein in urine,a decrease of GFR.increase ofChromium level in the body were also evident.Chromium concentration in urinemay reflect the chromium level in the body.and serve as a criterion for the detectionof renal damage induced by chromium.There...

47 workers exposed to chromate for an average of 9 years were investigated.It wasfound that not only the skin,mucous membrane of respiratory tract were damagedshowing abnormal features on X-ray films of chest,but also an apparent increase oflysozyme,β_2-microglobulin and protein in urine,a decrease of GFR.increase ofChromium level in the body were also evident.Chromium concentration in urinemay reflect the chromium level in the body.and serve as a criterion for the detectionof renal damage induced by chromium.There was a time-response relationship be-tween chromium and renal damage,and because of the close relation betweenlysozyme concentration and β_2-microglobulin concentration in urine,estimation oflysozyme concentration in urine instead of β_2-microglobulin can be used as an alter-native for the early detection of renal damage induced by chromate.

对47名接触铬尘平均9年的工人进行系统调查,发现除皮肤、粘膜受损和X 线胸片异常等临床症状外,尿lys、尿β_2-MG 和尿蛋白明显升高、GFR 下降;体内铬负荷水平明显升高.尿铬既可反映体铬负荷水平,又可作为慢性铬中毒性肾损害的检测指标.铬与肾损害间存在时间效应关系.尿lys 与尿β_2-MG 相关密切,可用尿lys 代替尿β_2-MG 测定,并可作为早期检测铬性肾损害的指标.

 
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