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     Having been raised for one week, mice of D1+D2 group were given low dose radiation(D1:25、 50、 75anD100mGy, dose rate: 12.5mGy·min~(-1)), 6h later mice of D2 group and D1 +D2 group were given challenging dose radiation(D2:1.5Gy, dose rate:287mGy·min~(-1)).
     常规饲养一周后对D1+D2组给予低剂量照射(剂量分别为25、50、75和100mGy,剂量率12.5mGy·min~(-1)),6小时后对D2组和D1+D2组给予攻击剂量照射(剂量1.5Gy,剂量率287mGy·min~(-1))。
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     48 h later, it was centrifuged (10000r/min) for 1.5 h and then residues were removed.
     48小时后离心(10000r/min)约1.5小时,去渣。
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     (3) LPS+ Galn/LPS(ETT)group: LPS 2mg/kg was administered three consecutive intraperitoneal injections at 24-h intervals. All animals were treated with i.p injection of Galn 13 mg/LPS 3μg/mouse, 72h later.
     (3)内毒素耐受组(ETT):连续三次间隔24小时腹腔注射LPS 2mg/kg,于LPS第三次注射24小时后腹腔注射Galn/LPS,剂量与Galn/LPS组相同。
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     c. with OCT and NC-8-12. Results showed that cell proliferation ofHCT116 induced by insulin was obviously inhibited by OCT or NC-8-12 at 10~(-8)mol/L 24h later after the cellswere incubated with them.
     结果发现体外生长实验:10~(-8)mol/L的OCT或NC-8-12作用HCT116、LOVO细胞株24小时后,能明显抑制胰岛素引起的肿瘤细胞增殖作用。
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     Results The bleeding time was shortened significantly after transfusion(P<0. 05) and the Fn level was higher after transfusion of 0.5h and still higher even 2h later.
     结果患者输注血浆冷沉淀后与输注前相比,出血时间明显缩短(P<0.01); 血浆Fn水平在输注后0.5小时显著提高(P<0.05),2小时后仍维持在较高水平。
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  “h later”译为未确定词的双语例句
     96 h later,the conditioned medium of kidney contained SCF 142.96 ng/L,IL-3 295.34 ng/L,IL-6 249.72 ng/L,GM-CSF 126.72 ng/L,EPO 148.96 IU/L.
     肾组织培养96 h:SCF 142.96 ng/LI、L-3 295.34 ng/L、IL-6 249.72 ng/L、GM-CSF 126.72 ng/L、EPO 148.96 IU/L。
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     ② 24 h later,the conditioned medium of kidney contained SCF 147.61 ng/L,IL-3 298.67 ng/L,IL-6 385.44 ng/L,GM-CSF 91.55 ng/L,EPO 158.09 IU/L.
     ②肾组织培养24 h:SCF 147.61 ng/LI、L-3 298.67ng/LI、L-6 385.44 ng/L、GM-CSF 91.55 ng/L、EPO 158.09 IU/L;
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     IC 50 (50% inhibitory concentration for cell growing) was 0 144μmol/ml and 0 061 μmol/ml and the ratio of them was 2 36: 1 after the treatment of cisplatin 72h later.
     半数细胞生长抑制浓度 (IC5 0 )分别为0 .144和 0 .0 6 1μmol/ ml,二者相差 2 .36倍。
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     The mean tinidazole concentration in breast milk was (14. 17±5. 746) μg · mL-1 in 2 h after intravenous infusion and (9. 364 ±5. 123) μg · mL-1 8 h later.
     替硝唑乳汁药物浓度在2h时为(14.17±5.746)μg·mL~(-1),8h时尚可测得(9.364±5.123)μg·mL~(-1)。
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     HPV-16 E6 protein was undetectable with Western blot assay 72 h later after 4 HPV-16 E6 specific siRNA transfected into CaSki cell.
     West- ern blot分析表明,4个HPV-16 E6 siRNA作用72 h后,未能检测到宫颈癌细胞中HPV-16 E6蛋白。
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  相似匹配句对
     Later ,M.
     随后,M.
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     And the main is the later.
     研究重点主要在后者。
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     Later,in 1968,T.
     1968年,T.
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     In the later paper of J.
     在后来的文章【6】中J.
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We studied dynamics of leukocyte composition and corticosterone content in the peripheral blood of male Norway rats after long-term selection for tame or aggressive behavior immediately after 20 min restrain as well as 2 and 4 h later.
      
The period of the maximum synthesis of plasmin-like enzymes was observed 6 h later than the period of the maximum growth rate ofB.
      
firmus 44b, and 3 h later than the maximum growth rate period ofB.
      
The content of the radionuclide had decreased to 17% 6 h later.
      
Previously, we demonstrated that severe hypobaric hypoxia (SHH) resulted in some enhancement of the content of Mn-SOD in rat hippocampal neurons 3 h later.
      
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The authors have established amethod for testing the thyroid func-tion of rats and made a study of thyroidfunction of normal rats. In this arti-cle, the method and result of the studyare reported. The thyroidal ~(125)I uptake: 50 maleand female normal Wistar rats about200 grams in weight were chosen forthis study. Less than 1 microcurie ofcarrier free ~(125)I was administered toeach rat by intraperitoneal injection.At the time of injection, an equalamount of ~(125)I solution was placedin a small rubber dish...

The authors have established amethod for testing the thyroid func-tion of rats and made a study of thyroidfunction of normal rats. In this arti-cle, the method and result of the studyare reported. The thyroidal ~(125)I uptake: 50 maleand female normal Wistar rats about200 grams in weight were chosen forthis study. Less than 1 microcurie ofcarrier free ~(125)I was administered toeach rat by intraperitoneal injection.At the time of injection, an equalamount of ~(125)I solution was placedin a small rubber dish of 0.3cm indiameter. This was used as a standard. It was measured by the external neckcounting technique. Fundamentally,the technique consisted in placing theanimal thyroid region under a scintil-lation detector using 5×5cm NaI(TI)scintillation crystal in a properlyshielded enclosure and the ~(125)I activitywas determined by a scaler (ModelGN 104) 4,6,24h after the injection of~(125)I. A collimator with upper hole5cm in diameter was used. The areacovered was a circle of approximately2.5cm in diameter. Counting was donewith the rat lying on its back withthe neck hyperextended, and the colli-mator touching the skin overlying thethyroid gland. After the external measurements werecompleted, the animals were killedand the two lobes of the thyroid glandwith intact isthmus were freed fromthe adjacent tissues and counted in atube in a scintillation well type counter(Model FH 408). Standard ~(125)I wasalso counted in 0.5ml saline in thewell type counter and the thyroidalradioactivity in vitro was also expres-sed as percentage of administereddose. This technique enables thyroidal ~(125)Imeasurement to be made with accu-racy and reproducibility in the rat. Invivo thyroid ~(125)I determination hasbeen compared against in vitro thyroid~(125)I determination in 20 rats undervarious levels of ~(125)I activity in verygood agreement with correspondingdetermination (r=+0.97). The thyroiduptake percent in control rats was38.5±11.1%(24h) and the uptake percentof dose/mg tissue was 1.78±0.6%.The maximal thyroid radioiodine up-take occurred in 24h. Serum thyroxine (T_4) concentration:The serum samples were assayed by acompetitive protein binding assay. Themean serum concentration of T_4 in 40rats was 5.56±1.24μg/100ml (3.4-8.5 μg/100ml). Serum triiodothyronine (T_3) and thy-rotropin (TSH) concentration: Theserum samples were assayed by radio-immunoassay. The mean serum concen-tration of T_3 in 26 rats was 58.8±22.6ng/100ml and the TSH was 2.2±0.6μIU/ml (43 rats). The quantity of ~3H-Leucine incor-porated into the thyroid protein wasdetermined in 35 rats which recieveda single intraperitoneal injection of 0.5microcurie DL-Leucine-4, 5-~3H pergm body weight and the animals werekilled 36h later. The radioactivity ofthyroid tissue was determined by aliquid scintillation system(Model FJ-353). The mean value of incorporationwas 143.7±51.8cpm per mg. The authors believe that the appli-cation of thyroid function tests report-ed here may be useful in the study oftoxicology and other subjects.

本文报告正常大鼠甲状腺功能状态的测定方法,计有甲状腺吸碘百分率,单位重量甲状腺吸碘百分率,~3H—亮氨酸掺入量,血清甲状腺素(T_4),血清三碘甲状腺原氨酸(T_3),和血清促甲状腺素(TSH)六项指标。并讨论了这些指标的意义及其可靠性。

The interaction between toosendanin (Toes) and botulinus toxin (BoTx) was examined with electron microscope. When Toes (9.0 mg/kg) was injected (sc) to mice and followed immediately or 1 h later by challenge of type A BoTx (1.7 LD 50 per mouse), the ultrastructural changes of NMJ were similar to those seen in the mice treated with Toes alone. The main changes included an obvious decrease in synaptic vesicle number and an increase in elongated vesicle number, In addition, myeloid body or phagosome-like...

The interaction between toosendanin (Toes) and botulinus toxin (BoTx) was examined with electron microscope. When Toes (9.0 mg/kg) was injected (sc) to mice and followed immediately or 1 h later by challenge of type A BoTx (1.7 LD 50 per mouse), the ultrastructural changes of NMJ were similar to those seen in the mice treated with Toes alone. The main changes included an obvious decrease in synaptic vesicle number and an increase in elongated vesicle number, In addition, myeloid body or phagosome-like structure can be seen more frequently. When Toes was administrated 5 or 24 h after the challenge of BoTx, however, the average density of synaptic vesicles in areas within 2500 from the presynaptic membrane of NMJ was approximately 90% higher as compared with the average density of synaptic vesicles of the mice treated with Toes alone. The results suggest that once BoTx has already acted on NMJ, it may prevent, in some manner, the vesicle-releasing process evolved by Toes subsequently administerted.

本实验用电子显微镜观察了小鼠在不同时间给以川楝素和肉毒毒素后,膈肌神经肌肉接头超微结构的改变。给川楝素后立即或1小时后给毒素,其改变与单给川楝素小鼠的相似。主要是突触小泡明显减少,长管形泡较多,髓膜样或自噬体样结构经常可见等变化。但是,如果先给毒素,5小时或24小时后再给川楝素,则突触小泡平均密度比单给川楝素小鼠的高约90%。表明预先作用于神经肌肉接头的肉毒毒素对川楝素引起的突触小泡减少有阻碍效应。其他改变与单给川楝素的相似。

This paper deals with the preparation and evaluation of sustained-release Doxycyeline hydrochloride in tablets(S-RDHT)by means of in vitro/invivo tests.The serum levels of healthy adult volunteers following the singleoral dose(200 mg)of both conventional tablets(4 subjects)and S-RDHT(4 subjects)were determined by a modified fluorimetry.The pharmacokineticparameters were fitted by non-linear least square method with TRS-80computer on the basis of one compartment model.The results showed thatthe peak time of S-RDHT...

This paper deals with the preparation and evaluation of sustained-release Doxycyeline hydrochloride in tablets(S-RDHT)by means of in vitro/invivo tests.The serum levels of healthy adult volunteers following the singleoral dose(200 mg)of both conventional tablets(4 subjects)and S-RDHT(4 subjects)were determined by a modified fluorimetry.The pharmacokineticparameters were fitted by non-linear least square method with TRS-80computer on the basis of one compartment model.The results showed thatthe peak time of S-RDHT appeared 2 h later than that of conventionaltablet,and both maintained the time of serum leve effective similarly.The acute gastric-irritation test on 9 volunteers demonstrated that S-RDHTcould reduce adverse reaction.

本文对自制的盐酸强力霉素缓释片进行了研究。测定了体外溶出速率,并用荧光法测定了8名健康受试者单剂量(200mg)口服缓释片(4人)和普通片(4人)(200mg)后的体内血药浓度。实验数据按单室模型并采用TRS-80型计算机和非线性最小二乘法模型嵌合程序进行迭代处理,求得动力学参数。结果表明:缓释片达峰时间较普通片晚2小时,而体内维特有效血浓时间基本相同。9名健康受试者进行的急性胃刺激试验证实:缓释片可减少药物对胃的刺激。

 
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