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zinc binding
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  锌结合
     The putative amino acid sequence shares the consensus zinc binding/gluzincin motif (HEXXHX (18)E) and a hydrophobic signal sequence with 20 amino acids in N-terminal region common to all aminopeptidases, but no glycosylphosphatidylinositol (GPI) anchor signal sequence in C-terminal region of APN1 was found.
     其推定的氨基酸序列具有氨肽酶N所共有的锌结合模体HEXXHX18E和N末端20个氨基酸的疏水性信号序列,但C末端没有糖基磷酯酰肌醇(glycosylphosphatidylinositol,GPI)锚添加信号序列。
短句来源
     (3)Serum zinc and activity of alkaline phosphatase in zinc depletion group were markedly lower than control group, but the serum zinc binding capa-city was lower than control group significantly.
     (3)严重缺锌组血清锌:碱性磷酸酶均显著低于正常对照组,而血清锌结合能力却明显高;
短句来源
     Hydrophobic signal sequence with 17 amino acids in N terminal region and a GPI anchor signal sequence with 22 amino acids in C terminal region were found in the deduced amino sequence which had the consensus zinc binding/gluzincin motif HEXXHX 18 E.
     其推定氨基酸序列具有锌结合模体HEXXHX18E ,N 末端具有 1 7个氨基酸的疏水性信号序列 ,C 末端还具有 2 2个氨基酸的糖基磷酯酰肌醇 (GPI)添加信号肽。
短句来源
     After exposure, the protein level of voltage-dependent anion channel, zinc binding oxidoreductase was down-regulated, while the protein level of S-adenosylmethionine synthetase and Actin was up-regulated. The effects of chromium on mitochondrial ion channel, cell stress response protein, amino acid biosynthesis and cytoskeleton and its relation were detected.
     结果表明,铬(Ⅵ)处理会导致细胞差异表达,其形成的蛋白质斑点有600多个,对其中改变明显的4个斑点进行肽指纹分析发现,电压依赖型阴离子通道和锌结合醌氧化还原酶表达量降低,而S-腺苷甲硫氨酸合成酶和肌动蛋白表达量上升,说明铬(Ⅵ)可能通过氧化胁迫应答、离子通道、氨基酸生物合成等发挥生物毒理作用.
短句来源
  “zinc binding”译为未确定词的双语例句
     Matrix metalloproteinases (MMPs) are a family of zinc binding, calcium-dependent endopeptidases that are expressed by various tissues and cell types and function by degrading extracellular matrix (ECM)components.
     基质金属蛋白酶(matrix metalloproteinases, MMPs)是一类结合锌离子、钙依赖的内肽酶家族,在多种组织和细胞存在,具有多种生物学功能:降解ECM及基底膜的有效成分,在ECM动态平衡中起着中心作用; 调节细胞粘附;
短句来源
     The putative amino acid sequences of the four cDNAs shared the consensus zinc binding/gluzincin motif HEXXHX18E and GAMEN sequence common to gluzincin aminopeptidases.
     这4个氨肽酶均具有锌离子结合模体(HEXXHX_(18)E)和GAMEN结构域,为典型的锌金属蛋白酶。
短句来源
     Pregnancy associate plasma protein A(PAPP A )is a zinc binding matrix metalloproteinase associated with insulin like growth factor (IGFs),which regulate IGFs positively,it also may be applicated in diagnosis,judgement prognoses and so on about acute coronary artery syndrome.
     妊娠相关血浆蛋白A(PAPP A)是胰岛素样生长因子相关的金属螯合蛋白酶 ,具有正向调节胰岛素样生长因子的作用 ,可用于急性冠脉综合征的诊断 ,判断预后等方面。
短句来源
     The metalloproteinase domain contained a conserved signature zinc binding motif HEXXHXXGXXH in the catalytic region and the CIM turn.
     金属蛋白酶区中含有典型的锌离子结合活性中心HEXXHXXGXXH序列及CIM转折 ;
短句来源
     Matrix metalloproteinases ( MMPs) are a family of zinc binding calcium dependent enzymes, whose main function is to degrade of ECM and prevent excessive matrix deposition.
     基质金属蛋白酶(MMPs)是一组降解细胞外基质(ECM)的内源性蛋白酶系。
短句来源
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  相似匹配句对
     ZINC
     锌
短句来源
     Zinc and Health
     锌与健康
短句来源
     A Research on Binding Mechanism of Sintered Zinc-Aluminum Coating
     烧结式锌铝涂层的粘结原理研究
短句来源
     protein binding;
     蛋白结合;
短句来源
     INDUCTION OF TESTIS METAL-BINDING PROTEIN OF RATS BY ZINC DEFICIENCY AND ITS
     缺锌对大鼠睾丸金属结合蛋白的诱导及其与睾酮水平的关系
短句来源
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  zinc binding
Furthermore, gel filtration studies using Sephadex G-75 and a 105,000 g supernatant fraction revealed two zinc binding protein peaks that bind 1.7 and 3.7 Μg Zn++/mg protein, respectively.
      
In previous cell transfection experiments we have shown that the zinc finger region confers an about 3 fold metal inducibility of transcription, due to its differential zinc binding.
      
However, the putative zinc binding site in fibrolase lacks the additional glutamate ligand found in thermolysin and subtilisin.
      
Effect of Zinc Binding on the Structure and Stability of Fibrolase, a Fibrinolytic Protein from Snake Venom
      
The zinc binding property is conferred by the histidine residues since modification of these residues by diethyl-pyrocarbonate would abolish this activity.
      
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This experiment was conducted to study adequate supplemental levels of zinc in diets for the growing Rong Chang and crossbred barrow. Zinc-deficient basal diet (30ppm zn) resulted in deficiency symptoms in Landrace X Hampshire Rong Chang (L×HR), Landrace X Rong Chang (L×R) and Rong Chang(R). The severity of dificiency was in the order of L XR, L X HR and R. Parakeratosis could be prevented by a supplement of 30ppm zinc in the diets. Itseeros that zinc requirement of the two crossbreds which grow faster is higher...

This experiment was conducted to study adequate supplemental levels of zinc in diets for the growing Rong Chang and crossbred barrow. Zinc-deficient basal diet (30ppm zn) resulted in deficiency symptoms in Landrace X Hampshire Rong Chang (L×HR), Landrace X Rong Chang (L×R) and Rong Chang(R). The severity of dificiency was in the order of L XR, L X HR and R. Parakeratosis could be prevented by a supplement of 30ppm zinc in the diets. Itseeros that zinc requirement of the two crossbreds which grow faster is higher than that of Rong Chang barrows. The Changes of serum alkaline phosphatase activity, serum zinc concentration and the percent of unsaturated serum-zinc binding capacity were determined. The results showed that the percent of unsaturated serum-zinc binding capacity seemed to be a sensitive indicotor of zinc nutrient status of pigs.

试验用72头三种类型的断奶仔猪研究荣昌猪及其杂交猪生长期饲粮锌的适宜添加量。试验结果表明饲喂基础饲粮(含30ppm锌)的长×汉荣和长×荣杂交猪及荣昌猪都出现缺锌症状,以长×荣杂交猪最敏感,荣昌猪最次。在该饲粮中加30ppm锌可防止猪的皮肤不全角化症的产生,但为获得理想的成绩和保证锌的生物学功能,建议20—35公斤阶段的三元和二元杂交猪饲粮中添加90ppm锌,荣昌猪加60ppm锌为宜。35—60公斤阶段,三元和二元杂交猪加60ppm锌,荣昌猪加30ppm锌为宜。生长速度较快,瘦肉率较高的杂交猪的锌添加量似有比荣昌猪高的趋势。

Zinc bound to organic matter in soil can be effectively divided into that weaklybound to organic matter(WBO) and that strongly bound to orgnic matter (SBO) by anextractant with 0.1mol/L Na_4P_2O_7 at pH 9.5.The WBO-Zn is more sensitive to Zincloaded levels,incubation period and soil pH than the SBO-Zn.On the other hand,WBO-Zn is more available for plant than SBO-Zn.The transformation betweenWBO-Zn,SBO-Zn and even others is one of the important buffer systms whichdirectly controls soil Zinc...

Zinc bound to organic matter in soil can be effectively divided into that weaklybound to organic matter(WBO) and that strongly bound to orgnic matter (SBO) by anextractant with 0.1mol/L Na_4P_2O_7 at pH 9.5.The WBO-Zn is more sensitive to Zincloaded levels,incubation period and soil pH than the SBO-Zn.On the other hand,WBO-Zn is more available for plant than SBO-Zn.The transformation betweenWBO-Zn,SBO-Zn and even others is one of the important buffer systms whichdirectly controls soil Zinc availability and toxicity for plant.

用 pH9.5 0.1mol/L Na_4P_2O_7和 H_2O_2有效地将土壤有机态锌区分为松结有机态及紧结有机态。松结有机态对负荷水平、培养时间及土壤 pH 等环境因子的反应较紧结有机态更为敏感;同时松结有机态锌对活性锌的贡献远远大于后者。土壤中松结有机态锌与紧结有机态锌的相互转化是直接影响土壤锌的营养供应或污染致毒程度的重要缓冲体系之一。

he effect of zinc deficient diet on growth,hematological Paramenters serum zinc,alkaline phosphatase and blood lipids of growing male rats was observed.Fifty male Sprague-Dawley rats with average body weight of 42±4g were divided into 5 groups of 10 animals each.Group 1 received a control diet(32.2mg Zn/kg).Croup 2 was given a zinc depletion diet(3.4mgZn/kg),group 3 with a zinc sufficient diet(84.9mg Zn/kg).Group 4 with zinc marginal deficient diet(5.5mg Zn/kg).Group 3,4,5were pair-fed to group 2.The experimental...

he effect of zinc deficient diet on growth,hematological Paramenters serum zinc,alkaline phosphatase and blood lipids of growing male rats was observed.Fifty male Sprague-Dawley rats with average body weight of 42±4g were divided into 5 groups of 10 animals each.Group 1 received a control diet(32.2mg Zn/kg).Croup 2 was given a zinc depletion diet(3.4mgZn/kg),group 3 with a zinc sufficient diet(84.9mg Zn/kg).Group 4 with zinc marginal deficient diet(5.5mg Zn/kg).Group 3,4,5were pair-fed to group 2.The experimental period was 26 days.The results showed: (1)The food intake and body weight gain in zinc depletion group were lower than control group significantly. Meantime the symptoms of zinc deficiency appeared such as loss of appetite.(2)Erythrocytes.hematocrit and her-moglobin in zinc depletion group were all significantly higher than control group,but there is no significant change among the pair-fed groups.(3)Serum zinc and activity of alkaline phosphatase in zinc depletion group were markedly lower than control group, but the serum zinc binding capa-city was lower than control group significantly.(4)The concentrations of cholesterol,triglyceride and phosphorus iipids in serum and lipid proteins were lower than control group.but there is no difference among pair fed-groups.

本文观察缺锌饲料对雄性SD幼鼠的生长、血液学多数、血清锌、碱性磷酸酶及血脂的影响。实验分五组:1组为正常对照组(饲料含锌量32.2μg/g);2组为严重缺锌组(饲料合锌量3.4μg/g),两组均自由进食;3组为锌足量组(饲料含锌84.9μg/g);4组为锌缺乏组(饲料含锌4.4μg/g);5组为锌边缘缺乏组(饲料含锌5.5μg/g)。后三组动物均与2组对喂。实验期26天。结果表明:(1)严重缺锌组体重和食物摄入量显著低于正常对照组,并且出现缺锌症状,最突出的是丧失食欲;(2)严重缺锌组红细胞数、血细胞容积、血红蛋白均明显高于正常对照组,而平均红细胞容积却显著低于正常对照组,但对喂组之间未见有意义的改变;(3)严重缺锌组血清锌:碱性磷酸酶均显著低于正常对照组,而血清锌结合能力却明显高;(4)严重缺锌组血清和脂蛋白中胆固醇、甘油三酯、磷脂浓度均显著低于正常对照组,但对喂组之间差别不明显。

 
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