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oncogen expression
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  “oncogen expression”译为未确定词的双语例句
     The effect of Helicobacter pylori infection on gastric epithelial cell apoptosis and oncogen expression
     幽门螺杆菌感染对胃上皮细胞凋亡及调节基因表达的影响
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     (2)The oncogen expression was mostly positive in the intima.
     (2)癌基因表达多位于血管斑块中的SMC;
短句来源
     These actions were not only due to the medium by the activity of vitamin A,but also due to its own activity. The mechanism of its action might be explained by its antioxidation,inhibition of the oncogen expression,damage of the nuclear structure etc.
     此作用不仅由于β-胡萝卜素的VitA活性,也由于其自身活性,其作用机制可能表现为抗氧化、抑制癌基因表达、损伤核结构等。
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  相似匹配句对
     Expression of E.
     将阳性重组质粒转化表达受体菌E.
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     The expression of E.
     研究了E.
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     (2)The oncogen expression was mostly positive in the intima.
     (2)癌基因表达多位于血管斑块中的SMC;
短句来源
     EXPRESSION OF ONCOGEN AND ANTI-ONCOGENE IN MOUSE LUNG CANCER INDUCED
     煤烟诱发的小鼠肺癌中c-myc及p53基因检测
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μm laser angioplasty(LA)was carried out on experimentally developed artherosclerotic stenosis of ab-dominal aorta in rabbits.The vascular tissues after AL were hybridized with probes of oncogenes labeled by ran-domly inserted digoxin-dUTP.The results showed that:(1)There was expression of oncogenes c-fos,c-jun,c-myc and N-ras in vascular wall after LA.(2)The oncogen expression was mostly positive in the intima.(3)c-fos and c-jun were expressed instantly and temporarily.while expression of c-myc and...

μm laser angioplasty(LA)was carried out on experimentally developed artherosclerotic stenosis of ab-dominal aorta in rabbits.The vascular tissues after AL were hybridized with probes of oncogenes labeled by ran-domly inserted digoxin-dUTP.The results showed that:(1)There was expression of oncogenes c-fos,c-jun,c-myc and N-ras in vascular wall after LA.(2)The oncogen expression was mostly positive in the intima.(3)c-fos and c-jun were expressed instantly and temporarily.while expression of c-myc and N-ras occurred later andpersisted for a longer time.It was concluded that expression of certain oncogenes in arterial smooth muscle cellscould be induced by laser irradiation.

通过建立兔腹主动脉粥样硬化性狭窄模型进行1.06μm激光血管成形术(LA),应用系列癌基因片段与地高辛-dUTP随机插入标记,进行血管组织的原位杂交。发现:(1)LA后血管壁可见c-fos、c-jun、C-myc和N-ras等癌基因表达;(2)癌基因表达多位于血管斑块中的SMC;(3)c-fos、c-jun表达迅速而短暂,c-myc和N-ras表达较迟,持续时间较长。结论:激光损伤可诱导动脉SMC中的某些癌基因表达。

Various doses of β-carotene(10-5,10-6 and 10-7 mol/L)could significantly inhibit the growth of human colorectal carcinoma cell line(SW1116) in-vitro and decrease its nuclear DNA contents.The distribution range of DNA-index(DI)value of cancer cells varied.These actions were not only due to the medium by the activity of vitamin A,but also due to its own activity. The mechanism of its action might be explained by its antioxidation,inhibition of the oncogen expression,damage of the nuclear structure etc.

不同剂量(10-5mol/L、10-6mol/L和10-7mol/L)β-胡萝卜素对体外人大肠癌细胞株SW1116增殖显示明显的抑制作用,癌细胞核DNA含量明显减少、分布改变。此作用不仅由于β-胡萝卜素的VitA活性,也由于其自身活性,其作用机制可能表现为抗氧化、抑制癌基因表达、损伤核结构等。

Objective To study the regulation mechanisms of bcl 2 oncogene in endometrial carcinoma. Methods A reverse transcription polymerase chain reaction (RT PCR) method was utilized to quantitate bcl 2 mRNA levels which regulated by estrogen(17 β estradiol) and tamoxifen in estrogen receptor (ER)(+) RL 952 endometrial carcinoma cells. Results bcl 2 mRNA level was detected in ER(+) RL 952 cells. 17 β estradiol stimulated a concentration dependent increase in bcl 2 mRNA level, while tamoxifen lead...

Objective To study the regulation mechanisms of bcl 2 oncogene in endometrial carcinoma. Methods A reverse transcription polymerase chain reaction (RT PCR) method was utilized to quantitate bcl 2 mRNA levels which regulated by estrogen(17 β estradiol) and tamoxifen in estrogen receptor (ER)(+) RL 952 endometrial carcinoma cells. Results bcl 2 mRNA level was detected in ER(+) RL 952 cells. 17 β estradiol stimulated a concentration dependent increase in bcl 2 mRNA level, while tamoxifen lead to a concentration dependent decrease in bcl 2 mRNA level. Conclusions bcl 2 oncogen expression in ER(+) endometrial carcinoma is regulated by estrogen and antiestrogen. Estrogen may up regulate the cell bcl 2 level to inhibit cell apoptosis,while tamoxifen may down regulate the cell bcl 2 level and induce apotosis.

目的 探讨雌激素与三苯氧胺对子宫内膜癌bcl2 癌基因的调节机理。方法 采用逆转录- 聚合酶链反应(RTPCR) 法,检测子宫内膜癌细胞雌激素受体(ER) 阳性RL952 细胞中bcl2mRNA表达水平,及其与雌激素和三苯氧胺作用后的变化。结果 ER阳性RL952 细胞有bcl2 mRNA表达。经10-12 、10-10 、10-8 、10-7 mol/L17β雌二醇(E2)与RL952 细胞作用72 小时后,bcl2 与βactinmRNA的比值分别为6.94 ±0.03、7 .15 ±0 .02、7.47 ±0.01、8.44 ±0 .01 ,呈逐渐升高趋势;经10-8 、10-7 、10- 6、10-5 mol/L三苯氧胺与RL952 细胞作用72 小时后,bcl2 与βactin mRNA 的比值分别为3 .62±0.03 、2 .87 ±0.01、2.23±0 .01、1 .98 ±0 .02,呈逐渐下降趋势。结论 雌激素可通过促进bcl2的表达,抑制细胞凋亡,在ER阳性的子宫内膜癌发病中起了一定作用;三苯氧胺则降低bcl2 的表达水平,促进细胞凋亡,可能产生治疗子宫...

目的 探讨雌激素与三苯氧胺对子宫内膜癌bcl2 癌基因的调节机理。方法 采用逆转录- 聚合酶链反应(RTPCR) 法,检测子宫内膜癌细胞雌激素受体(ER) 阳性RL952 细胞中bcl2mRNA表达水平,及其与雌激素和三苯氧胺作用后的变化。结果 ER阳性RL952 细胞有bcl2 mRNA表达。经10-12 、10-10 、10-8 、10-7 mol/L17β雌二醇(E2)与RL952 细胞作用72 小时后,bcl2 与βactinmRNA的比值分别为6.94 ±0.03、7 .15 ±0 .02、7.47 ±0.01、8.44 ±0 .01 ,呈逐渐升高趋势;经10-8 、10-7 、10- 6、10-5 mol/L三苯氧胺与RL952 细胞作用72 小时后,bcl2 与βactin mRNA 的比值分别为3 .62±0.03 、2 .87 ±0.01、2.23±0 .01、1 .98 ±0 .02,呈逐渐下降趋势。结论 雌激素可通过促进bcl2的表达,抑制细胞凋亡,在ER阳性的子宫内膜癌发病中起了一定作用;三苯氧胺则降低bcl2 的表达水平,促进细胞凋亡,可能产生治疗子宫内膜癌的效应。

 
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